PL3386531T3 - Zastosowanie wariantów peptydu natriuretycznego typu c w leczeniu choroby zwyrodnieniowej stawów - Google Patents

Zastosowanie wariantów peptydu natriuretycznego typu c w leczeniu choroby zwyrodnieniowej stawów

Info

Publication number
PL3386531T3
PL3386531T3 PL16852866T PL16852866T PL3386531T3 PL 3386531 T3 PL3386531 T3 PL 3386531T3 PL 16852866 T PL16852866 T PL 16852866T PL 16852866 T PL16852866 T PL 16852866T PL 3386531 T3 PL3386531 T3 PL 3386531T3
Authority
PL
Poland
Prior art keywords
degrous
treatment
type
natriuretic peptide
joint disease
Prior art date
Application number
PL16852866T
Other languages
English (en)
Inventor
Charles A. O'neill
Todd M. Oppeneer
Jason K. Pinkstaff
Original Assignee
Biomarin Pharmaceutical Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomarin Pharmaceutical Inc. filed Critical Biomarin Pharmaceutical Inc.
Publication of PL3386531T3 publication Critical patent/PL3386531T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728Hyaluronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/2242Atrial natriuretic factor complex: Atriopeptins, atrial natriuretic protein [ANP]; Cardionatrin, Cardiodilatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL16852866T 2015-12-08 2016-12-08 Zastosowanie wariantów peptydu natriuretycznego typu c w leczeniu choroby zwyrodnieniowej stawów PL3386531T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562264682P 2015-12-08 2015-12-08
PCT/US2016/065520 WO2017100400A2 (en) 2015-12-08 2016-12-08 Use of c-type natriuretic peptide variants to treat osteoarthritis
EP16852866.9A EP3386531B1 (en) 2015-12-08 2016-12-08 Use of c-type natriuretic peptide variants to treat osteoarthritis

Publications (1)

Publication Number Publication Date
PL3386531T3 true PL3386531T3 (pl) 2022-02-28

Family

ID=59013378

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16852866T PL3386531T3 (pl) 2015-12-08 2016-12-08 Zastosowanie wariantów peptydu natriuretycznego typu c w leczeniu choroby zwyrodnieniowej stawów

Country Status (17)

Country Link
US (2) US11202819B2 (pl)
EP (2) EP3386531B1 (pl)
JP (1) JP7104625B2 (pl)
KR (1) KR102941538B1 (pl)
CN (1) CN108697766A (pl)
AU (2) AU2016365751B2 (pl)
CA (1) CA3007315A1 (pl)
DK (1) DK3386531T3 (pl)
ES (1) ES2901769T3 (pl)
HR (1) HRP20211908T1 (pl)
HU (1) HUE057083T2 (pl)
IL (1) IL259690B2 (pl)
MX (1) MX2018006986A (pl)
PL (1) PL3386531T3 (pl)
PT (1) PT3386531T (pl)
RU (1) RU2759679C2 (pl)
WO (1) WO2017100400A2 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3008017C (en) 2016-01-08 2024-01-02 Ascendis Pharma Growth Disorders A/S Controlled-release cnp agonists with reduced side-effects
AU2017205688C1 (en) 2016-01-08 2022-03-10 Ascendis Pharma Growth Disorders A/S Cnp prodrugs with carrier attachment at the ring moiety
NZ743488A (en) 2016-01-08 2023-02-24 Ascendis Pharma Growth Disorders As Controlled-release cnp agonists with low initial npr-b activity
US10835578B2 (en) 2016-01-08 2020-11-17 Ascendis Pharma Growth Disorders A/S CNP prodrugs with large carrier moieties
AU2017205694B2 (en) 2016-01-08 2022-05-26 Ascendis Pharma Growth Disorders A/S Controlled-release CNP agonists with low NPR-C binding
AU2017205690B2 (en) 2016-01-08 2022-04-28 Ascendis Pharma Growth Disorders A/S Controlled-release CNP agonists with increased NEP stability
HRP20230385T1 (hr) 2016-09-29 2023-06-23 Ascendis Pharma Growth Disorders A/S Kombinirana terapija sa cnp agonistima s kontroliranim oslobađanjem
CN112752556A (zh) * 2018-04-27 2021-05-04 雷米生物科学公司 新的医疗装置、递送运载体及其制造
EP3923906A1 (en) * 2019-02-11 2021-12-22 Ascendis Pharma Growth Disorders A/S Dry pharmaceutical formulations of cnp conjugates
JP7837333B2 (ja) * 2020-11-25 2026-03-30 プロリンクス エルエルシー C-ナトリウム利尿ペプチドの徐放性ヒドロゲルコンジュゲート
US20240238428A1 (en) * 2021-05-11 2024-07-18 Texas Tech University System Targeted selenium conjugates as countermeasures for viral and cellular pathogens
CN119013035A (zh) * 2021-12-07 2024-11-22 生物马林药物股份有限公司 骨相关病症的c型利钠肽疗法
US12077561B2 (en) 2022-11-02 2024-09-03 Novo Nordisk A/S CNP compounds
WO2024104922A1 (en) 2022-11-14 2024-05-23 Ascendis Pharma Growth Disorders A/S Method of improving skeletal muscle function
JP2026510974A (ja) 2023-03-20 2026-04-10 アセンディス ファーマ グロース ディスオーダーズ エー/エス 軟骨形成不全症のヒト対象における胸腰椎奇形の治療の方法
KR20250098109A (ko) * 2023-12-21 2025-07-01 주식회사 펩트론 나트륨이뇨 펩타이드 유사체 및 이의 용도
CN117801123B (zh) * 2024-02-29 2024-05-03 天津凯莱英生物科技有限公司 沃索利肽可溶性中间体、中间体制备方法及沃索利肽的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252714A (en) 1990-11-28 1993-10-12 The University Of Alabama In Huntsville Preparation and use of polyethylene glycol propionaldehyde
JP2809533B2 (ja) 1991-01-31 1998-10-08 壽之 松尾 Cnp類似体ペプチド
US5824784A (en) 1994-10-12 1998-10-20 Amgen Inc. N-terminally chemically modified protein compositions and methods
IL142118A0 (en) 2001-03-20 2002-03-10 Prochon Biotech Ltd Method and composition for treatment of skeletal dysplasias
WO2005094889A1 (ja) * 2004-03-31 2005-10-13 Chugai Seiyaku Kabushiki Kaisha 関節炎症治療剤又は予防剤
EP3620530A1 (en) * 2004-03-31 2020-03-11 Kazuwa Nakao Composition for increasing body height
EP2217620A2 (en) 2007-11-21 2010-08-18 BioMarin Pharmaceutical Inc. Variants of c-type natriuretic peptide
HUE032582T2 (en) 2009-05-20 2017-09-28 Biomarin Pharm Inc Variants of c-type natriuretic peptide
EP2658979B1 (en) * 2010-12-27 2018-02-14 Alexion Pharmaceuticals, Inc. Compositions comprising natriuretic peptides and methods of use thereof

Also Published As

Publication number Publication date
KR20180088459A (ko) 2018-08-03
HRP20211908T1 (hr) 2022-03-04
PT3386531T (pt) 2021-12-29
ES2901769T3 (es) 2022-03-23
IL259690B (en) 2022-10-01
JP2019505486A (ja) 2019-02-28
EP3386531B1 (en) 2021-10-13
AU2016365751A1 (en) 2018-06-21
IL259690A (en) 2018-07-31
HUE057083T2 (hu) 2022-04-28
US12214015B2 (en) 2025-02-04
KR102941538B1 (ko) 2026-03-19
US20190247467A1 (en) 2019-08-15
RU2018124600A (ru) 2020-01-13
CN108697766A (zh) 2018-10-23
RU2759679C2 (ru) 2021-11-16
AU2016365751B2 (en) 2023-12-21
JP7104625B2 (ja) 2022-07-21
EP3386531A2 (en) 2018-10-17
MX2018006986A (es) 2018-09-05
RU2018124600A3 (pl) 2020-01-13
RU2021132347A (ru) 2022-03-24
DK3386531T3 (da) 2022-01-03
EP4019038A2 (en) 2022-06-29
CA3007315A1 (en) 2017-06-15
US11202819B2 (en) 2021-12-21
WO2017100400A2 (en) 2017-06-15
EP4019038A3 (en) 2022-09-28
AU2024201852A1 (en) 2024-04-11
WO2017100400A3 (en) 2017-10-26
IL259690B2 (en) 2023-02-01
US20220160836A1 (en) 2022-05-26

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