PL3391041T3 - Automatyczny kliniczny układ i sposób diagnostyczny - Google Patents

Automatyczny kliniczny układ i sposób diagnostyczny

Info

Publication number
PL3391041T3
PL3391041T3 PL16819054T PL16819054T PL3391041T3 PL 3391041 T3 PL3391041 T3 PL 3391041T3 PL 16819054 T PL16819054 T PL 16819054T PL 16819054 T PL16819054 T PL 16819054T PL 3391041 T3 PL3391041 T3 PL 3391041T3
Authority
PL
Poland
Prior art keywords
diagnostic system
clinical diagnostic
automated clinical
automated
diagnostic
Prior art date
Application number
PL16819054T
Other languages
English (en)
Inventor
Tobias Franz
Uwe Kobold
Peter Kupser
Roland THIELE
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3391041T3 publication Critical patent/PL3391041T3/pl

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1885—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/24—Automatic injection systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/466—Flow patterns using more than one column with separation columns in parallel
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/60—Construction of the column
    • G01N30/6034—Construction of the column joining multiple columns
    • G01N30/6039—Construction of the column joining multiple columns in series
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/62—Detectors specially adapted therefor
    • G01N30/72—Mass spectrometers
    • G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
    • G01N30/724—Nebulising, aerosol formation or ionisation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584—Control arrangements for automatic analysers
    • G01N35/0092—Scheduling
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/40—Concentrating samples
    • G01N1/405—Concentrating samples by adsorption or absorption
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N2030/022—Column chromatography characterised by the kind of separation mechanism
    • G01N2030/027—Liquid chromatography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8804—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 automated systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
PL16819054T 2015-12-18 2016-12-16 Automatyczny kliniczny układ i sposób diagnostyczny PL3391041T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15201395 2015-12-18
EP16819054.4A EP3391041B1 (en) 2015-12-18 2016-12-16 Automated clinical diagnostic system and method
PCT/EP2016/081538 WO2017103180A1 (en) 2015-12-18 2016-12-16 Automated clinical diagnostic system and method

Publications (1)

Publication Number Publication Date
PL3391041T3 true PL3391041T3 (pl) 2020-03-31

Family

ID=55070729

Family Applications (1)

Application Number Title Priority Date Filing Date
PL16819054T PL3391041T3 (pl) 2015-12-18 2016-12-16 Automatyczny kliniczny układ i sposób diagnostyczny

Country Status (8)

Country Link
US (1) US10775355B2 (pl)
EP (2) EP3614138B1 (pl)
JP (2) JP6694509B2 (pl)
KR (1) KR102658086B1 (pl)
CN (1) CN108291896B (pl)
ES (1) ES2761822T3 (pl)
PL (1) PL3391041T3 (pl)
WO (1) WO2017103180A1 (pl)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP1500616A2 (en) 2015-12-14 2017-07-28 Pecsi Tudomanyegyetem Data collecting and processing method and arrangement for soft-tomographic examinations
ES2894840T3 (es) * 2017-07-04 2022-02-16 Hoffmann La Roche Sistema y procedimiento de diagnóstico clínico automatizado
CA3076601C (en) * 2017-10-19 2022-08-16 Tl Genomics Inc. Chip for cell classification
EP3594681B1 (en) * 2018-07-10 2024-08-28 Alpha M.O.S. Device for characterising a fluid sample
ES2999149T3 (en) * 2018-08-27 2025-02-24 Hoffmann La Roche Sample injector with sample loop and buffer loop
JP6964065B2 (ja) 2018-12-10 2021-11-10 株式会社日立ハイテク 液体クロマトグラフ質量分析装置
CN113330314A (zh) 2019-01-17 2021-08-31 豪夫迈·罗氏有限公司 用于关于完整蛋白质水平的基于LC-MS的HbA1c测量的自动化样品工作流程
KR20210117268A (ko) * 2019-01-17 2021-09-28 에프. 호프만-라 로슈 아게 Lc-ms 기초된 hba1c 계측을 위한 고속 표본 작업 흐름
US11730358B2 (en) * 2019-02-15 2023-08-22 California Institute Of Technology Tear flow measurement device
CN113396328B (zh) 2019-02-22 2024-09-10 株式会社日立高新技术 分析装置
EP3748354B1 (en) 2019-06-04 2022-04-06 F. Hoffmann-La Roche AG Quick liquid exchange in liquid chromatography
CN110672864B (zh) * 2019-06-26 2023-05-02 北京华视诺维医疗科技有限公司 临床医疗体液检测质控方法、设备及系统
EP3760292B1 (en) 2019-07-01 2023-04-12 F. Hoffmann-La Roche AG Liquid chromatography systems
US12529709B2 (en) 2019-07-04 2026-01-20 Hitachi High-Tech Corporation Automatic analysis device
CN114846326B (zh) * 2019-12-17 2025-02-11 豪夫迈·罗氏有限公司 用于校准具有多个重复硬件组件的至少一个分析装置的方法
ES3056969T3 (en) * 2019-12-19 2026-02-25 Hoffmann La Roche Techniques for monitoring an analyzer including multiple liquid chromatography streams
EP3896443B1 (en) * 2020-04-15 2024-05-01 F. Hoffmann-La Roche AG Analytical system and method including switching between liquid chromatography fluidic streams
WO2021248124A1 (en) 2020-06-05 2021-12-09 Snapdragon Chemistry, Inc. Automated online chromatographic sample dilution and preparation system
EP3992627B1 (en) 2020-10-28 2025-01-22 Roche Diagnostics GmbH Liquid chromatography - stream equivalence by single stream calibration
CN116670514A (zh) * 2020-12-16 2023-08-29 株式会社日立高新技术 检体预处理装置的控制方法
EP4729935A2 (en) * 2020-12-22 2026-04-22 F. Hoffmann-La Roche AG Automated clinical diagnostic system and method
EP4272006A4 (en) * 2020-12-30 2025-02-26 Beckman Coulter, Inc. Clinical laboratory automation system with single calibrator
JP2023117671A (ja) * 2022-02-14 2023-08-24 東ソー株式会社 キャリブレーターの測定方法および液体クロマトグラフ装置
CN118671205A (zh) * 2023-03-15 2024-09-20 北京华大吉比爱生物技术有限公司 用于液相色谱和质谱分析的样品处理方法
JP2024165957A (ja) * 2023-05-18 2024-11-28 アークレイ株式会社 分析システム
WO2025009341A1 (ja) * 2023-07-04 2025-01-09 株式会社日立ハイテク 液体クロマトグラフ装置、及び、その制御方法
GB202408176D0 (en) * 2024-06-07 2024-07-24 Micromass Ltd automated clinical analysis
WO2025253132A1 (en) * 2024-06-07 2025-12-11 Micromass Uk Limited Automated clinical analysis
US20260079136A1 (en) 2024-09-18 2026-03-19 Dionex Softron Gmbh Method for optimizing a liquid chromatography system and system for liquid chromatography
WO2026074076A1 (en) 2024-10-04 2026-04-09 Roche Diagnostics Gmbh Method for derivatizing and method for determining an analyte of interest

Family Cites Families (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4364263A (en) * 1980-09-15 1982-12-21 Burroughs Wellcome Co. High pressure liquid chromatographic system
EP0255026A3 (en) * 1986-07-23 1988-10-19 Takeda Chemical Industries, Ltd. Automatic analysis method and apparatus for enzyme reaction
US5800784A (en) * 1996-07-09 1998-09-01 Horn; Marcus J. Chemical sample treatment system and cassette, and methods for effecting multistep treatment process
US6436292B1 (en) * 1999-04-02 2002-08-20 Symyx Technologies, Inc. Parallel high-performance liquid chromatography with post-separation treatment
US6296771B1 (en) 1999-04-02 2001-10-02 Symyx Technologies, Inc. Parallel high-performance liquid chromatography with serial injection
AU4450900A (en) * 1999-04-23 2000-11-10 Advanced Bioanalytical Services, Inc. High-throughput parallel liquid chromatography system
US20030044846A1 (en) * 2001-04-03 2003-03-06 Gary Eldridge Screening of chemical compounds purified from biological sources
US6881540B2 (en) * 2000-02-23 2005-04-19 Rensselaer Polytechnic Institute High throughtput screening of potential displacer molecules
US6635173B2 (en) 2000-12-28 2003-10-21 Cohesive Technologies, Inc. Multi column chromatography system
US7691645B2 (en) * 2001-01-09 2010-04-06 Agilent Technologies, Inc. Immunosubtraction method
US7244961B2 (en) * 2002-08-02 2007-07-17 Silicon Valley Scientific Integrated system with modular microfluidic components
US7132650B1 (en) * 2003-09-26 2006-11-07 Nanostream, Inc. High throughput multi-dimensional sample analysis
US6812458B2 (en) * 2002-08-08 2004-11-02 Nanostream, Inc. Systems and methods for high-throughput microfluidic sample analysis
US6936167B2 (en) * 2002-10-31 2005-08-30 Nanostream, Inc. System and method for performing multiple parallel chromatographic separations
WO2004040295A1 (en) * 2002-10-31 2004-05-13 Nanostream, Inc. Parallel detection chromatography systems
US6987263B2 (en) * 2002-12-13 2006-01-17 Nanostream, Inc. High throughput systems and methods for parallel sample analysis
WO2004101151A1 (en) * 2003-05-08 2004-11-25 Nanostream, Inc. Sample preparation for parallel chromatography
US6962658B2 (en) * 2003-05-20 2005-11-08 Eksigent Technologies, Llc Variable flow rate injector
DE112004000997B4 (de) * 2003-06-06 2018-04-12 Waters Technologies Corp. (N.D.Ges.D. Staates Delaware) Vorrichtung und Verfahren zum Durchführen paralleler Prozesse
CN1773288A (zh) * 2004-11-09 2006-05-17 盛进生物工程(深圳)有限公司 侧流分析系统和方法
EP1874424A2 (en) * 2005-04-14 2008-01-09 California Institute of Technology Integrated chromatography devices and systems for monitoring analytes in real time and methods for manufacturing the same
JP5156738B2 (ja) * 2006-06-06 2013-03-06 エフ．ホフマン−ラ ロシュ アーゲー 全血試料の特異的溶血
US20080020469A1 (en) * 2006-07-20 2008-01-24 Lawrence Barnes Method for scheduling samples in a combinational clinical analyzer
TW200813430A (en) * 2006-08-01 2008-03-16 Brooks Rand Llc Automated system for detection of chemical compounds
US7815803B2 (en) 2007-06-14 2010-10-19 Roche Diagnostics Operations, Inc. Preparation of samples for LC-MS/MS using magnetic particles
US8133451B2 (en) * 2008-08-28 2012-03-13 Microfluidic Systems, Inc. Sample preparation apparatus
JP5591742B2 (ja) * 2010-06-30 2014-09-17 シスメックス株式会社 検体検査装置の処理能力情報生成装置、検体検査装置、検体検査装置の処理能力情報生成方法、及びコンピュータプログラム
CN103370627B (zh) * 2010-10-29 2016-05-11 恩姆菲舍尔科技公司 用于样品制备和分析的自动化系统的系统布局
US20130206653A1 (en) * 2010-10-29 2013-08-15 John E. Brann Modular Multiple-Column Chromatography Cartridge
WO2012058619A1 (en) * 2010-10-29 2012-05-03 Cohesive Technologies Inc. Lc-ms configuration for purification and detection of analytes having a broad range of hydrophobicities
US10054569B2 (en) * 2010-10-29 2018-08-21 Thermo Finnigan Llc Method and system for liquid chromatography fluidic monitoring
EP2652513A2 (en) * 2010-12-17 2013-10-23 F.Hoffmann-La Roche Ag Automatically controlling a plurality of devices of a separation and detection process for quantitative sample analysis
WO2013151920A1 (en) * 2012-04-02 2013-10-10 Siemens Healthcare Diagnostics Inc. Virtual sample queues
CN103308611B (zh) * 2012-09-07 2017-02-22 五行通医疗科技（武汉）有限公司 一种多通道进样的泌尿系结石病因诊断系统及应用方法
US9404900B2 (en) * 2012-12-21 2016-08-02 Thermo Finnigan Llc System for analysis of phase-I and phase-II metabolites and parent compounds without hydrolysis
CN104111341B (zh) * 2013-04-16 2017-10-17 深圳迈瑞生物医疗电子股份有限公司 自动分析装置及其分析方法和分析系统
EP3825697B1 (en) * 2014-06-11 2025-07-30 F. Hoffmann-La Roche AG In-vitro diagnostic analysis method and system
US9857339B2 (en) * 2015-01-06 2018-01-02 Waters Technologies Corporation Automated sampling and reaction system for high pressure liquid chromatography and other types of detection

Also Published As

Publication number Publication date
US20180292368A1 (en) 2018-10-11
JP6900542B2 (ja) 2021-07-07
US10775355B2 (en) 2020-09-15
EP3391041B1 (en) 2019-10-16
CN108291896A (zh) 2018-07-17
EP3614138B1 (en) 2021-04-21
ES2761822T3 (es) 2020-05-21
JP2020128990A (ja) 2020-08-27
JP6694509B2 (ja) 2020-05-13
KR20180093944A (ko) 2018-08-22
WO2017103180A1 (en) 2017-06-22
EP3391041A1 (en) 2018-10-24
EP3614138A1 (en) 2020-02-26
KR102658086B1 (ko) 2024-04-16
JP2019505773A (ja) 2019-02-28
CN108291896B (zh) 2020-11-20

Similar Documents

Publication Publication Date Title
PL3391041T3 (pl) Automatyczny kliniczny układ i sposób diagnostyczny
ZA201803907B (en) System and method of determining the health & gender of a chick
EP3001196B8 (en) Blood testing system and method
IL260678B (en) Systems and methods to improve diagnosis of diseases
IL253567A0 (en) Method and system for automatic vision testing
EP3317428A4 (en) Method and system for diagnostic testing
IL250855A0 (en) A system and method for analyzing a motor task
IL247540A0 (en) System and method for endoscopic measurement
EP3347495A4 (en) METHOD AND SYSTEM FOR MICROBIOMY-DERIVED DIAGNOSES AND THERAPEUTIC AGENTS FOR DISEASES ASSOCIATED WITH GASTROINTESTINAL HEALTH
SG11201706341RA (en) Systems and methods for biological analysis
GB201908185D0 (en) Reductant concentration diagnostic system and methods
GB201600873D0 (en) System and method for endoscope callibration
ZA201800288B (en) System and method for tokenization
EP3299918A4 (en) Abnormality diagnosis system and abnormality diagnosis method
EP3229093A4 (en) Abnormality diagnosis method and abnormality diagnosis system
IL258063A (en) Test system and test method
GB201700935D0 (en) Nox sensor diagnosis system and method
TWI559897B (en) System and method for measuring physiological parameters
SG11201700087UA (en) On-site diagnostic system and the method thereof
IL251134B (en) A system and method for monitoring and managing laboratory procedures
IL252690A0 (en) Method and system for improving physiological response
SG10201407018YA (en) System and method for processing heartbeat information
GB201500665D0 (en) Patient handling system and method
GB201718691D0 (en) Clinical support system and method
SG11201706222PA (en) Attaching System And Attaching Method