PL3416658T3 - Funkcjonalna ludzka komórka śródbłonka rogówki i jej zastosowanie - Google Patents
Funkcjonalna ludzka komórka śródbłonka rogówki i jej zastosowanieInfo
- Publication number
- PL3416658T3 PL3416658T3 PL17709487.7T PL17709487T PL3416658T3 PL 3416658 T3 PL3416658 T3 PL 3416658T3 PL 17709487 T PL17709487 T PL 17709487T PL 3416658 T3 PL3416658 T3 PL 3416658T3
- Authority
- PL
- Poland
- Prior art keywords
- application
- endothelial cell
- corneal endothelial
- human functional
- functional corneal
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
- A61L27/38—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells
- A61L27/3804—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix containing added animal cells characterised by specific cells or progenitors thereof, e.g. fibroblasts, connective tissue cells, kidney cells
- A61L27/3808—Endothelial cells
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Wood Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Neurology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Materials For Medical Uses (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016026426 | 2016-02-15 | ||
| JP2016026424 | 2016-02-15 | ||
| JP2016026423 | 2016-02-15 | ||
| JP2016026425 | 2016-02-15 | ||
| JP2016077450 | 2016-04-07 | ||
| PCT/JP2017/005386 WO2017141926A1 (en) | 2016-02-15 | 2017-02-14 | Human functional corneal endothelial cell and application thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3416658T3 true PL3416658T3 (pl) | 2023-09-04 |
Family
ID=58261691
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17709487.7T PL3416658T3 (pl) | 2016-02-15 | 2017-02-14 | Funkcjonalna ludzka komórka śródbłonka rogówki i jej zastosowanie |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20190083543A1 (pl) |
| EP (2) | EP4218773A1 (pl) |
| JP (6) | JP7008337B2 (pl) |
| ES (1) | ES2947826T3 (pl) |
| PL (1) | PL3416658T3 (pl) |
| WO (1) | WO2017141926A1 (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3178138A1 (en) | 2011-12-06 | 2013-06-13 | Astellas Institute For Regenerative Medicine | Method of directed differentiation producing corneal endothelial cells, compositions thereof, and uses thereof |
| JP7008337B2 (ja) | 2016-02-15 | 2022-02-10 | 京都府公立大学法人 | ヒト機能性角膜内皮細胞およびその応用 |
| CN107629999A (zh) * | 2017-10-18 | 2018-01-26 | 清华大学深圳研究生院 | 一种增加间充质干细胞外泌体产生及分泌的方法 |
| US12350294B2 (en) | 2018-01-16 | 2025-07-08 | Keio University | Medium comprising serum replacement, IGF1, STAT3 activator and adrenal gland hormone without BFGF or rock inhibitor for producing corneal endothelial substitute cells from iPS cells and a method thereof |
| US12553027B2 (en) | 2018-12-12 | 2026-02-17 | The Johns Hopkins University | Generation and cryopreservation of pluripotent stem cell-derived clinical grade corneal endothelial cells |
| WO2020213969A2 (ko) * | 2019-04-17 | 2020-10-22 | 연세대학교 산학협력단 | 각막 내피 세포의 기능 부전 진단용 바이오마커 |
| JP2020200296A (ja) * | 2019-06-13 | 2020-12-17 | 久貴 藤本 | 角膜内皮障害の予防及び/又は治療のための薬剤 |
| US12230397B2 (en) * | 2019-08-21 | 2025-02-18 | Case Western Reserve University | Assessment of endothelial cells and corneas at risk from ophthalmological images |
| US20230257700A1 (en) * | 2020-02-27 | 2023-08-17 | Kyoto Prefectural Public University Corporation | Functional human corneal endothelial cells and application thereof |
| WO2022025239A1 (ja) * | 2020-07-31 | 2022-02-03 | 学校法人同志社 | 角膜内皮細胞注入療法の治療効果増強法 |
| JP7361431B2 (ja) * | 2020-10-22 | 2023-10-16 | 京都府公立大学法人 | ヒト角膜内皮細胞及び/又はヒト角膜内皮前駆細胞の保存方法 |
| CN112538458B (zh) * | 2020-11-26 | 2025-10-31 | 北京孟眸生物科技有限公司 | 用于重编程细胞的方法 |
| WO2023282337A1 (ja) | 2021-07-07 | 2023-01-12 | 株式会社セルージョン | 角膜内皮代替細胞を含有する治療用組成物 |
| EP4368181A4 (en) | 2021-07-07 | 2025-06-25 | Cellusion Inc. | Cell seeding agent and substrate for cell transplantation use |
| CN114507635B (zh) * | 2022-01-24 | 2024-03-22 | 上海纽仁生物医药科技有限公司 | 一种动物神经系统内皮细胞单细胞的分离方法 |
| WO2023190941A1 (ja) * | 2022-03-31 | 2023-10-05 | 学校法人同志社 | 培養由来成分を含まない角膜内皮細胞製剤及びその製造法 |
| WO2023230171A2 (en) * | 2022-05-24 | 2023-11-30 | University Of Pittsburgh - Of Thecommonwealth System Of Highereducation | Compositions and methods of treating corneal scarring |
| EP4655392A2 (en) * | 2023-01-27 | 2025-12-03 | Universiteit Maastricht | Methods for selecting cultured corneal endothelial cells |
| WO2024182683A1 (en) * | 2023-03-01 | 2024-09-06 | The Regents Of The University Of California | Rapid, accurate, and reproducible screening of endothelial cell morphology in diseased and healthy corneas |
| KR20250024502A (ko) * | 2023-08-11 | 2025-02-18 | 재단법인 아산사회복지재단 | 분화 유도된 각막 내피 세포를 포함하는 각막 질환 예방 또는 치료용 약학적 조성물 |
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| US4678783B1 (en) | 1983-11-04 | 1995-04-04 | Asahi Chemical Ind | Substituted isoquinolinesulfonyl compounds |
| EP1195372A1 (en) | 1994-04-18 | 2002-04-10 | Mitsubishi Pharma Corporation | N-heterocyclic substituted benzamide derivatives with antihypertensive activity |
| JP3421217B2 (ja) | 1995-11-20 | 2003-06-30 | 麒麟麦酒株式会社 | Rho標的タンパク質Rhoキナーゼ |
| WO1999020620A1 (en) | 1997-10-22 | 1999-04-29 | Nippon Shinyaku Co Ltd | Isoquinoline derivative and drug |
| DE69931051D1 (de) | 1998-05-25 | 2006-06-01 | Santen Pharmaceutical Co Ltd | Neue vinylbenzolderivate |
| US6410278B1 (en) | 1998-11-09 | 2002-06-25 | Eiken Kagaku Kabushiki Kaisha | Process for synthesizing nucleic acid |
| AU2878200A (en) | 1999-02-11 | 2000-08-29 | Schepens Eye Research Institute, Inc., The | Growth medium for human corneal endothelial cells |
| TWI336328B (en) | 2001-03-23 | 2011-01-21 | Bayer Healthcare Llc | Rho-kinase inhibitors |
| JP4329003B2 (ja) | 2001-03-23 | 2009-09-09 | バイエル コーポレイション | Rhoキナーゼ阻害剤 |
| CA2707827A1 (en) | 2001-04-11 | 2002-10-24 | Senju Pharmaceutical Co., Ltd. | Visual function disorder improving agents containing rho kinase inhibitors |
| US7199147B2 (en) | 2001-06-12 | 2007-04-03 | Dainippon Sumitomo Pharma Co., Ltd. | Rho kinase inhibitors |
| JP4505228B2 (ja) | 2002-01-10 | 2010-07-21 | バイエル・シェーリング・ファルマ・アクチェンゲゼルシャフト | Rho−キナーゼ阻害剤 |
| US6690307B2 (en) | 2002-01-22 | 2004-02-10 | Nokia Corporation | Adaptive variable length coding of digital video |
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| JPWO2004009555A1 (ja) | 2002-07-22 | 2005-11-17 | 旭化成ファーマ株式会社 | 5−置換イソキノリン誘導体 |
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| US7160894B2 (en) | 2003-06-06 | 2007-01-09 | Asahi Kasei Pharma Corporation | Tricyclic compound |
| EP1644365A2 (en) | 2003-07-02 | 2006-04-12 | Biofocus Discovery Ltd | Pyrazine and pyridine derivatives as rho kinase inhibitors |
| WO2005039564A1 (en) | 2003-10-02 | 2005-05-06 | Vertex Pharmaceuticals Incorporated | Phthalimide compounds useful as protein kinase inhibitors |
| WO2005037198A2 (en) | 2003-10-06 | 2005-04-28 | Glaxo Group Limited | Preparation of 1,7-disubstituted azabenzimidazoles as kinase inhibitors |
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| JP4764823B2 (ja) | 2003-10-06 | 2011-09-07 | グラクソ グループ リミテッド | キナーゼ阻害剤としての1,6−二置換アザベンゾイミダゾールの調製 |
| EP2468729B1 (en) | 2003-10-15 | 2013-12-25 | Ube Industries, Ltd. | Novel indazole derivative |
| JP2007015928A (ja) | 2003-10-15 | 2007-01-25 | Ube Ind Ltd | 新規オレフィン誘導体 |
| JP2007008816A (ja) | 2003-10-15 | 2007-01-18 | Ube Ind Ltd | 新規イソキノリン誘導体 |
| WO2005080394A1 (en) | 2004-02-24 | 2005-09-01 | Bioaxone Therapeutique Inc. | 4-substituted piperidine derivatives |
| WO2005103050A2 (en) | 2004-04-02 | 2005-11-03 | Vertex Pharmaceuticals Incorporated | Azaindoles useful as inhibitors of rock and other protein kinases |
| JPWO2006057270A1 (ja) | 2004-11-26 | 2008-06-05 | 旭化成ファーマ株式会社 | 含窒素3環化合物 |
| EP1932841B1 (en) | 2005-08-30 | 2014-01-01 | Asahi Kasei Pharma Corporation | Sulfonamide compound |
| KR20180031066A (ko) | 2007-08-29 | 2018-03-27 | 센주 세이야꾸 가부시키가이샤 | 각막 내피 세포 접착 촉진제 |
| US9078932B2 (en) * | 2008-02-04 | 2015-07-14 | Emmetrope, Inc. | Magnetic cells for localizing delivery and tissue repair |
| US8606848B2 (en) | 2009-09-10 | 2013-12-10 | Opentv, Inc. | Method and system for sharing digital media content |
| WO2011080984A1 (en) * | 2009-12-29 | 2011-07-07 | Senju Pharmaceutical Co., Ltd. | Therapeutic agent (y - 39983 ) for corneal endothelial dysfunction |
| JP5835693B2 (ja) * | 2010-02-05 | 2015-12-24 | 株式会社角膜再生研究所 | 角膜内皮細胞の培養方法、移植用角膜内皮細胞シートの製造方法および角膜内皮細胞培養キット |
| EP2547082B1 (en) | 2010-03-08 | 2019-06-26 | Nec Corporation | Mobile communication terminal apparatus, method for controlling power consumption of mobile communication terminal apparatus, and recording medium |
| KR102124149B1 (ko) | 2010-05-12 | 2020-06-18 | 인터디지탈 매디슨 페이튼트 홀딩스 | 통합된 유효성 맵 코딩을 위한 방법 및 장치 |
| WO2013051722A1 (ja) | 2011-10-06 | 2013-04-11 | 学校法人 慶應義塾 | 角膜内皮細胞の製造方法 |
| EP2799537B1 (en) * | 2011-12-28 | 2021-09-22 | Kyoto Prefectural Public University Corporation | Normalization of culture of corneal endothelial cells |
| WO2014007402A1 (ja) * | 2012-07-06 | 2014-01-09 | 京都府公立大学法人 | 眼細胞の分化マーカーおよび分化制御 |
| EP2875124B1 (en) | 2012-07-18 | 2019-03-27 | Singapore Health Services Pte Ltd | Cell culture of corneal endothelial cells |
| WO2014038639A1 (ja) * | 2012-09-07 | 2014-03-13 | 日本ケミカルリサーチ株式会社 | 間葉系幹細胞の馴化培地を含有する角膜内皮細胞培養用培地 |
| WO2015016371A1 (ja) * | 2013-07-30 | 2015-02-05 | 京都府公立大学法人 | 角膜内皮細胞マーカー |
| CA2928626C (en) | 2013-11-14 | 2023-03-14 | The Doshisha | Drug for treating corneal endothelium by promoting cell proliferation or inhibiting cell damage |
| JP2016077450A (ja) | 2014-10-15 | 2016-05-16 | タツタ電線株式会社 | 医療用チューブ |
| JP7008337B2 (ja) | 2016-02-15 | 2022-02-10 | 京都府公立大学法人 | ヒト機能性角膜内皮細胞およびその応用 |
-
2017
- 2017-02-14 JP JP2018561784A patent/JP7008337B2/ja active Active
- 2017-02-14 WO PCT/JP2017/005386 patent/WO2017141926A1/en not_active Ceased
- 2017-02-14 EP EP23160003.2A patent/EP4218773A1/en active Pending
- 2017-02-14 PL PL17709487.7T patent/PL3416658T3/pl unknown
- 2017-02-14 EP EP17709487.7A patent/EP3416658B1/en active Active
- 2017-02-14 ES ES17709487T patent/ES2947826T3/es active Active
- 2017-02-14 US US16/078,002 patent/US20190083543A1/en active Pending
-
2020
- 2020-02-13 JP JP2020022799A patent/JP6954682B2/ja active Active
- 2020-02-13 JP JP2020022800A patent/JP7453669B2/ja active Active
- 2020-10-20 US US17/074,912 patent/US20210046124A1/en active Pending
-
2023
- 2023-12-06 JP JP2023205812A patent/JP2024019306A/ja active Pending
-
2025
- 2025-07-03 US US19/259,859 patent/US20260034177A1/en active Pending
- 2025-10-29 JP JP2025182944A patent/JP2026021433A/ja active Pending
- 2025-10-29 JP JP2025182943A patent/JP2026012325A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2026012325A (ja) | 2026-01-23 |
| EP3416658B1 (en) | 2023-03-22 |
| JP2024019306A (ja) | 2024-02-08 |
| JP2020073602A (ja) | 2020-05-14 |
| WO2017141926A1 (en) | 2017-08-24 |
| JP2019510509A (ja) | 2019-04-18 |
| US20190083543A1 (en) | 2019-03-21 |
| JP2020072753A (ja) | 2020-05-14 |
| EP3416658A1 (en) | 2018-12-26 |
| JP7453669B2 (ja) | 2024-03-21 |
| US20210046124A1 (en) | 2021-02-18 |
| EP4218773A1 (en) | 2023-08-02 |
| JP2026021433A (ja) | 2026-02-10 |
| JP7008337B2 (ja) | 2022-02-10 |
| JP6954682B2 (ja) | 2021-10-27 |
| ES2947826T3 (es) | 2023-08-21 |
| US20260034177A1 (en) | 2026-02-05 |
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