PL3455213T3 - Sposób oczyszczania związków kannabinoidowych przez symulowaną chromatografię z ruchomym złożem - Google Patents
Sposób oczyszczania związków kannabinoidowych przez symulowaną chromatografię z ruchomym złożemInfo
- Publication number
- PL3455213T3 PL3455213T3 PL16728841T PL16728841T PL3455213T3 PL 3455213 T3 PL3455213 T3 PL 3455213T3 PL 16728841 T PL16728841 T PL 16728841T PL 16728841 T PL16728841 T PL 16728841T PL 3455213 T3 PL3455213 T3 PL 3455213T3
- Authority
- PL
- Poland
- Prior art keywords
- moving bed
- simulated moving
- bed chromatography
- compounds via
- cannabinoid compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/78—Ring systems having three or more relevant rings
- C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
- B01D15/185—Simulated moving beds characterised by the components to be separated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/001—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain
- C07C37/002—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by modification in a side chain by transformation of a functional group, e.g. oxo, carboxyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/02—Preparation of carboxylic acid esters by interreacting ester groups, i.e. transesterification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Sustainable Development (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pyrane Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2016/060905 WO2017194173A1 (en) | 2016-05-13 | 2016-05-13 | Method for purifying cannabinoid compounds |
| EP16728841.4A EP3455213B1 (en) | 2016-05-13 | 2016-05-13 | Method for purifying cannabinoid compounds via simulated moving bed chromatography |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3455213T3 true PL3455213T3 (pl) | 2022-04-04 |
Family
ID=56121022
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL16728841T PL3455213T3 (pl) | 2016-05-13 | 2016-05-13 | Sposób oczyszczania związków kannabinoidowych przez symulowaną chromatografię z ruchomym złożem |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10647691B2 (pl) |
| EP (1) | EP3455213B1 (pl) |
| CN (1) | CN109153661B (pl) |
| CA (1) | CA3023760C (pl) |
| DK (1) | DK3455213T3 (pl) |
| ES (1) | ES2907623T3 (pl) |
| PL (1) | PL3455213T3 (pl) |
| PT (1) | PT3455213T (pl) |
| WO (1) | WO2017194173A1 (pl) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10239808B1 (en) | 2016-12-07 | 2019-03-26 | Canopy Holdings, LLC | Cannabis extracts |
| US11213558B2 (en) | 2017-05-17 | 2022-01-04 | Orochem Technologies, Inc. | CBX extraction-isolation process |
| US10189762B1 (en) | 2017-07-07 | 2019-01-29 | Orochem Technologies, Inc. | Process for purification and separation of cannabinoids, from dried hemp and cannabis leaves |
| WO2019152736A1 (en) | 2018-01-31 | 2019-08-08 | Canopy Holdings, LLC | Hemp powder |
| CN112105606A (zh) * | 2018-03-07 | 2020-12-18 | 索卡蒂科技俄勒冈有限公司 | 大麻素的连续分离以及大麻素向δ8-四氢大麻酚和δ9-四氢大麻酚的转化 |
| US11192870B2 (en) | 2018-03-07 | 2021-12-07 | Socati Technologies—Oregon, Llc | Continuous isolation of cannabidiol and conversion of cannabidiol to delta 8-tetrahydrocannabinol and delta 9-tetrahydrocannabinol |
| US11851415B2 (en) * | 2018-03-07 | 2023-12-26 | Cleen Technology Inc. | Continuous isolation of cannabidiol and cannabinoids and conversion of cannabidiol to delta 8-tetrahydrocannabinol and delta 9-tetrahydrocannabinol |
| WO2020001770A1 (en) * | 2018-06-28 | 2020-01-02 | Symrise Ag | Synthesis of (+)-cannabinoids and their therapeutic effects |
| WO2020028198A1 (en) | 2018-08-03 | 2020-02-06 | Biomass Oil Separation Solutions, Llc | Processes and apparatus for extraction of substances and enriched extracts from plant material |
| CA3110208A1 (en) * | 2018-08-20 | 2020-02-27 | Bessor Pharma, Llc | Applications of known and novel cannabinoids |
| US11324718B2 (en) * | 2018-10-09 | 2022-05-10 | Sartorius Chromatography Equipment | Method for purifying cannabinoids |
| WO2020077153A1 (en) | 2018-10-10 | 2020-04-16 | Canopy Holdings, LLC | Synthesis of cannabigerol |
| WO2020117688A2 (en) * | 2018-12-04 | 2020-06-11 | Orochem Technologies Inc. | Process for purifying tetrahydrocannabinol using a chromatographic stationary phase |
| US10413845B1 (en) | 2018-12-14 | 2019-09-17 | Socati Technologies | Processes for solvent extraction of cannabinoids, terpenes and flavonoids from biomass |
| CN109734591A (zh) * | 2018-12-26 | 2019-05-10 | 江苏暨明医药科技有限公司 | 一种大麻二酚中间体及其制备方法与及应用 |
| CN113950467A (zh) * | 2019-05-10 | 2022-01-18 | 贝努维亚制造有限责任公司 | 生产大麻二酚或次大麻二酚的方法以及生产大麻二酚或次大麻二酚的中间体 |
| CN111943813B (zh) * | 2019-05-17 | 2023-04-14 | 上海特化医药科技有限公司 | 大麻二酚类化合物的制备方法 |
| CA3179235A1 (en) * | 2019-05-23 | 2020-11-26 | Kare Chemical Technologies Inc. | Catalytic cannabinoid processes and precursors |
| CN110270134A (zh) * | 2019-05-31 | 2019-09-24 | 江苏哈工药机科技股份有限公司 | 一种高纯度cbd分离纯化装置及其分离纯化方法 |
| US10799546B1 (en) | 2019-07-26 | 2020-10-13 | Biomass Oil Separation Solutions, Llc | Modular, integrated process and apparatus for extracting, refining and remediating active substances from plant material |
| CN110724589B (zh) * | 2019-08-27 | 2023-01-10 | 桂林莱茵生物科技股份有限公司 | 一种制备大麻二酚联产大麻全谱油的方法 |
| US11542243B1 (en) | 2019-09-26 | 2023-01-03 | FusionFarms, LLC | Method of converting delta9-THC to delta10-THC and the purification of the delta10-THC by crystallization |
| WO2021068053A1 (en) * | 2019-10-11 | 2021-04-15 | Compassionate Analytics Inc. | Test kits and methods for identification of cannabinoid compounds |
| CN110746275A (zh) * | 2019-11-08 | 2020-02-04 | 河南汉麻生物科技有限公司 | 一种利用连续色谱系统分离大麻二酚的方法 |
| CN113896616A (zh) * | 2020-07-06 | 2022-01-07 | 复旦大学 | 一种大麻二酚的制备方法 |
| CN114432187A (zh) * | 2020-11-03 | 2022-05-06 | 北京东方淼森生物科技有限公司 | 一种桃花油的制备方法及在化妆品中的应用 |
| WO2022125966A1 (en) * | 2020-12-10 | 2022-06-16 | Orochem Technologies Inc. | Process for removing thc from cannabinoids |
| CN112843788B (zh) * | 2021-01-19 | 2022-10-28 | 温州大学新材料与产业技术研究院 | 一种采用流动相独立环外置换的温度梯度模拟移动床装置及其分离方法 |
| CN113135885A (zh) * | 2021-04-07 | 2021-07-20 | 上海同田生物技术有限公司 | 一种高速逆流色谱分离纯化四氢次大麻酚的方法 |
| LU500093B1 (de) * | 2021-04-27 | 2022-10-31 | K D Pharma Bexbach Gmbh | Verfahren zum Trennen einer Stoffmischung |
| JP2024518338A (ja) * | 2021-04-27 | 2024-05-01 | カーデー・ファルマ・ベクスバッハ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 物質混合物を分離するための方法 |
| CN113683490B (zh) * | 2021-08-02 | 2022-03-25 | 云南翰谷生物科技有限公司 | 一种次大麻二酚晶体的制备方法 |
| CN115010690B (zh) * | 2022-06-06 | 2023-03-21 | 云南翰谷生物科技有限公司 | 一种高纯大麻酚晶体制备方法 |
| CN115385780B (zh) * | 2022-08-26 | 2024-02-27 | 晨光生物科技集团股份有限公司 | 一种次大麻二酚结晶多晶型物及其制备方法和应用 |
| WO2025213198A1 (en) | 2024-04-05 | 2025-10-09 | Council For Scientific And Industrial Research | Chemistry process for the production of cannabinoid compounds |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5342971A (en) | 1992-12-29 | 1994-08-30 | The Australian National University | Process for the preparation of dibenzo[b,d]pyrans |
| WO2002045115A1 (en) | 2000-11-28 | 2002-06-06 | Orion Electric Co., Ltd. | Color plasma display panel with an improvement of color temperature and brightness |
| DE10106024B4 (de) | 2001-02-09 | 2004-10-14 | Thc Pharm Gmbh | Verfahren zur Herstellung von Dronabinol |
| GB0112752D0 (en) * | 2001-05-25 | 2001-07-18 | Johnson Matthey Plc | Synthesis of cannabinoids |
| GB0329635D0 (en) | 2003-12-23 | 2004-01-28 | Johnson Matthey Plc | Process for purifying trans-tetrahydrocannabinol |
| CA2573859A1 (en) | 2004-07-19 | 2006-01-26 | Cilag Ltd. | Method for obtaining pure tetrahydrocannabinol |
| TWI369203B (en) | 2004-11-22 | 2012-08-01 | Euro Celtique Sa | Methods for purifying trans-(-)-△9-tetrahydrocannabinol and trans-(+)-△9-tetrahydrocannabinol |
| DE102005028937B4 (de) | 2005-06-22 | 2009-07-23 | Bionorica Ag | Verfahren zur Herstellung von Dronabinol |
| CA2623723A1 (en) * | 2005-09-29 | 2007-04-12 | Amr Technology, Inc. | Process for production of delta-9-tetrahydrocannabinol |
| GB0807915D0 (en) | 2008-05-01 | 2008-06-04 | Resolution Chemicals Ltd | Production of delta 9 tetrahydrocannabinol |
| DE102009019322A1 (de) | 2009-04-30 | 2010-11-11 | The Health Concept Gmbh | Verfahren zur Herstellung von Synthetischen Cannabinoiden |
| CA2866787C (en) | 2011-09-29 | 2021-05-18 | Thc Pharm Gmbh The Health Concept | Cannabinoid carboxylic acids, salts of cannabinoid carboxylic acids, and the production and uses of same |
| ES2547354T3 (es) * | 2013-09-03 | 2015-10-05 | Symrise Ag | Mezclas de compuestos cannabinoides, su preparación y uso |
-
2016
- 2016-05-13 EP EP16728841.4A patent/EP3455213B1/en active Active
- 2016-05-13 US US16/300,205 patent/US10647691B2/en active Active
- 2016-05-13 WO PCT/EP2016/060905 patent/WO2017194173A1/en not_active Ceased
- 2016-05-13 ES ES16728841T patent/ES2907623T3/es active Active
- 2016-05-13 PL PL16728841T patent/PL3455213T3/pl unknown
- 2016-05-13 CA CA3023760A patent/CA3023760C/en active Active
- 2016-05-13 DK DK16728841.4T patent/DK3455213T3/da active
- 2016-05-13 PT PT167288414T patent/PT3455213T/pt unknown
- 2016-05-13 CN CN201680085631.5A patent/CN109153661B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| CN109153661A (zh) | 2019-01-04 |
| US20190144414A1 (en) | 2019-05-16 |
| EP3455213B1 (en) | 2021-11-24 |
| US10647691B2 (en) | 2020-05-12 |
| ES2907623T3 (es) | 2022-04-25 |
| PT3455213T (pt) | 2022-03-01 |
| EP3455213A1 (en) | 2019-03-20 |
| CA3023760A1 (en) | 2017-11-16 |
| WO2017194173A1 (en) | 2017-11-16 |
| CA3023760C (en) | 2023-10-03 |
| CN109153661B (zh) | 2023-01-17 |
| DK3455213T3 (da) | 2022-03-07 |
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