PL3455351T3 - Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach - Google Patents

Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach

Info

Publication number
PL3455351T3
PL3455351T3 PL17726562.6T PL17726562T PL3455351T3 PL 3455351 T3 PL3455351 T3 PL 3455351T3 PL 17726562 T PL17726562 T PL 17726562T PL 3455351 T3 PL3455351 T3 PL 3455351T3
Authority
PL
Poland
Prior art keywords
microalgae
fatty acids
polyunsaturated fatty
acids production
increasing omega
Prior art date
Application number
PL17726562.6T
Other languages
English (en)
Inventor
Anne-Cecile V. Bayne
Ross E. Zirkle
Original Assignee
Dsm Ip Assets B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Ip Assets B.V. filed Critical Dsm Ip Assets B.V.
Publication of PL3455351T3 publication Critical patent/PL3455351T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01HNEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H5/00Angiosperms, i.e. flowering plants, characterised by their plant parts; Angiosperms characterised otherwise than by their botanic taxonomy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C12N15/8247Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine involving modified lipid metabolism, e.g. seed oil composition
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • C12N9/1025Acyltransferases (2.3)
    • C12N9/1029Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409Fatty acids
    • C12P7/6427Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432Eicosapentaenoic acids [EPA]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/64Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436Fatty acid esters
    • C12P7/6445Glycerides
    • C12P7/6472Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y203/00Acyltransferases (2.3)
    • C12Y203/01Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C12Y203/01085Fatty-acid synthase (2.3.1.85)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
PL17726562.6T 2016-05-12 2017-05-11 Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach PL3455351T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662335498P 2016-05-12 2016-05-12
PCT/EP2017/061347 WO2017194683A1 (en) 2016-05-12 2017-05-11 Method of increasing omega-3 polyunsaturated fatty acids production in microalgae

Publications (1)

Publication Number Publication Date
PL3455351T3 true PL3455351T3 (pl) 2022-11-21

Family

ID=58800789

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17726562.6T PL3455351T3 (pl) 2016-05-12 2017-05-11 Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach

Country Status (8)

Country Link
US (1) US11987819B2 (pl)
EP (1) EP3455351B1 (pl)
JP (1) JP6966040B2 (pl)
KR (1) KR102442450B1 (pl)
CN (1) CN109477079A (pl)
ES (1) ES2930078T3 (pl)
PL (1) PL3455351T3 (pl)
WO (1) WO2017194683A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20250340910A1 (en) * 2021-10-20 2025-11-06 University Of Puerto Rico Fatty acid production in escherichia coli
CN121511310A (zh) * 2023-07-14 2026-02-10 帝斯曼知识产权资产管理有限公司 具有高epa含量的微生物油及其制备方法

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5380831A (en) 1986-04-04 1995-01-10 Mycogen Plant Science, Inc. Synthetic insecticidal crystal protein gene
US4743546A (en) 1985-02-13 1988-05-10 Biotechnica International, Inc. Controlled gene excision
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5130242A (en) 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
CN1176577C (zh) 1995-10-13 2004-11-24 陶氏农业科学有限公司 编码杀虫性晶体蛋白的核苷酸序列及其应用
JP2002510205A (ja) 1997-06-04 2002-04-02 カルジーン エルエルシー ポリケチド様合成遺伝子を植物内で発現させることによる多不飽和脂肪酸の製造
US6566583B1 (en) 1997-06-04 2003-05-20 Daniel Facciotti Schizochytrium PKS genes
IL134242A (en) 1997-08-01 2003-06-24 Martek Biosciences Corp Dha-containing nutritional compositions and methods for their production
US20070244192A1 (en) 1999-01-14 2007-10-18 Martek Biosciences Corporation Plant seed oils containing polyunsaturated fatty acids
US7211418B2 (en) 1999-01-14 2007-05-01 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
US7247461B2 (en) 1999-01-14 2007-07-24 Martek Biosciences Corporation Nucleic acid molecule encoding ORFA of a PUFA polyketide synthase system and uses thereof
US8003772B2 (en) 1999-01-14 2011-08-23 Martek Biosciences Corporation Chimeric PUFA polyketide synthase systems and uses thereof
US7217856B2 (en) 1999-01-14 2007-05-15 Martek Biosciences Corporation PUFA polyketide synthase systems and uses thereof
KR101429236B1 (ko) 2000-01-19 2014-08-12 마텍 바이오싸이언스스 코포레이션 무용매 추출 방법
TWI377253B (en) 2001-04-16 2012-11-21 Martek Biosciences Corp Product and process for transformation of thraustochytriales microorganisms
JP4280158B2 (ja) 2002-12-27 2009-06-17 富士フイルム株式会社 ドコサヘキサエン酸生産能を有する微生物及びその利用
US20040172682A1 (en) 2003-02-12 2004-09-02 Kinney Anthony J. Production of very long chain polyunsaturated fatty acids in oilseed plants
KR101234199B1 (ko) 2003-03-26 2013-02-20 마텍 바이오싸이언스스 코포레이션 Pufa 폴리케타이드 신타제 시스템 및 이의 용도
US7208590B2 (en) 2003-07-15 2007-04-24 Abbott Laboratories Genes involved in polyketide synthase pathways and uses thereof
DE102004017370A1 (de) 2004-04-08 2005-10-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh PUFA-PKS Gene aus Ulkenia
US7348473B2 (en) 2004-09-30 2008-03-25 Dow Agrosciences Llc Canola cultivar NQC02CNX25
US7456340B2 (en) 2005-04-04 2008-11-25 Dow Agrosciences Llc Canola cultivar NQC02CNX21
US7355100B2 (en) 2004-09-30 2008-04-08 Dow Agrosciences Llc Canola cultivar NQC02CNX12
WO2006135866A2 (en) 2005-06-10 2006-12-21 Martek Biosciences Corporation Pufa polyketide synthase systems and uses thereof
US7868228B2 (en) 2006-01-31 2011-01-11 Monsanto Technology Llc Phosphopantetheinyl transferases from bacteria
WO2008142562A1 (en) 2007-04-30 2008-11-27 Michael Brailsford Paint remover
CN102648207A (zh) 2009-03-16 2012-08-22 马太克生物科学公司 在网粘菌门微生物中产生蛋白质
EP2408797B1 (en) * 2009-03-19 2017-03-15 DSM IP Assets B.V. Polyunsaturated fatty acid synthase nucleic acid molecules and polypeptides, compositions, and methods of making and uses thereof
NZ601757A (en) 2010-01-19 2015-01-30 Dsm Ip Assets Bv Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
TW201144442A (en) 2010-05-17 2011-12-16 Dow Agrosciences Llc Production of DHA and other LC-PUFAs in plants
JP5911479B2 (ja) * 2010-06-01 2016-04-27 ディーエスエム アイピー アセッツ ビー.ブイ. 細胞からの脂質の抽出およびそれに由来する生産物
EP2652027A2 (en) 2010-12-13 2013-10-23 DSM IP Assets B.V. Polymer composition containing a polymer, which polymer contains monomer units of a dimerised fatty acid
TW201307553A (zh) 2011-07-26 2013-02-16 Dow Agrosciences Llc 在植物中生產二十二碳六烯酸(dha)及其他長鏈多元不飽和脂肪酸(lc-pufa)之技術
CN104871255A (zh) 2012-12-18 2015-08-26 帝斯曼知识产权资产管理有限公司 本发明涉及包含电缆套的电缆
BR102014029437A2 (pt) * 2013-11-26 2015-07-07 Dow Agrosciences Llc Produção de ácidos graxos ômega-3 polinsaturados de cadeia longa em culturas oleaginosas por uma pufa sintase de traustoquitrídio

Also Published As

Publication number Publication date
WO2017194683A1 (en) 2017-11-16
JP6966040B2 (ja) 2021-11-10
KR20190004798A (ko) 2019-01-14
KR102442450B1 (ko) 2022-09-14
BR112018073164A2 (pt) 2019-04-30
CN109477079A (zh) 2019-03-15
JP2019514382A (ja) 2019-06-06
ES2930078T3 (es) 2022-12-07
US11987819B2 (en) 2024-05-21
EP3455351A1 (en) 2019-03-20
EP3455351B1 (en) 2022-08-24
US20190144838A1 (en) 2019-05-16

Similar Documents

Publication Publication Date Title
ZA201704820B (en) Process for increasing the stability of a composition comprising polyunsaturated omega-3 fatty acids
ZA201704821B (en) Process for increasing the stability of a composition comprising polyunsaturated omega-6 fatty acids
SG10201507002PA (en) Production Of Fatty Acids Esters
PL3613833T3 (pl) Kompozycja długołańcuchowych jednonienasyconych kwasów tłuszczowych i długołańcuchowy wielonienasycony kwas tłuszczowy oraz sposób ich wytwarzania
EP3710591A4 (en) PRODUCTION OF POLYUNSATURATED FATTY ACIDS EXTRACTED FROM SEAWEED
EP3191577A4 (en) Methods for efficient production of polyunsaturated fatty acids (pufa) in rhodosporidium and rhodotorula species
EP3208261A4 (en) Method for preparing glyceride type polyunsaturated fatty acids
EP3290499A4 (en) Method for manufacturing long chain polyunsaturated fatty acid-containing fat
IL245787A0 (en) Production of long-chain omega-3 polyunsaturated fatty acids in oilseed crops by triosteocitride synthase pufa
ZA201806415B (en) Method of producing fatty acids
EP3109315A4 (en) Method for the enrichment of microalgae biomass in polyunsaturated fatty acids
EP2928314A4 (en) OXIDIZED STABILIZED FATS CONTAINING OMEGA 3 POLYUNSATURATED FATTY ACIDS AND THEIR USES
ZA201800636B (en) Lower fatty carboxylic acid alkyl ester production method
SG10201912618XA (en) Free polyunsaturated fatty acid-containing composition and manufacturing method therefor
SG10201914018UA (en) Process of omega-hydroxyl fatty acid production
EP3040415A4 (en) Omega-3 UNSATURATED FATTY ACID ENZYME AND METHOD FOR PRODUCING EICOSAPENTAENOIC ACID
PL3455351T3 (pl) Sposób zwiększania wytwarzania wielonienasyconych kwasów tłuszczowych omega-3 w mikroalgach
GB2528618B (en) Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP3076961A4 (en) Omega-3 fatty acid articles of manufacture, and methods and apparatus for making same
EP3099782A4 (en) Factors for the production and accumulation of polyunsaturated fatty acids (pufas) derived from pufa synthases
PL3302032T3 (pl) Wytwarzanie wielonienasyconych kwasów tłuszczowych (PUFA) z zastosowaniem nowej, modularnej syntazy kwasu dokozaheksaenowego (DHA)
ZA201705670B (en) Combination of a retinoid and a diol and polyunsaturated fatty acid ester
GB2558977B8 (en) Method for production of fatty acids
AU2014902471A0 (en) Production of increased levels of long chain polyunsaturated fatty acids in plant cells
GB201222184D0 (en) Production of omega-3 long chain polyunsaturated fatty acids