PL348920A1 - Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia - Google Patents

Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia

Info

Publication number
PL348920A1
PL348920A1 PL99348920A PL34892099A PL348920A1 PL 348920 A1 PL348920 A1 PL 348920A1 PL 99348920 A PL99348920 A PL 99348920A PL 34892099 A PL34892099 A PL 34892099A PL 348920 A1 PL348920 A1 PL 348920A1
Authority
PL
Poland
Prior art keywords
utilization
preventing
pyrimidine derivatives
treating cerebral
cerebral ischaemia
Prior art date
Application number
PL99348920A
Inventor
Gerd Steiner
Kurt Schellhaas
Wilfried Lubisch
Uta Holzenkamp
Dorothea Starck
Monika Knopp
Laszlo Szabo
Franz Emling
Francisco Javier Garcia-Ladona
Hans-Peter Hofmann
Liliane Unger
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of PL348920A1 publication Critical patent/PL348920A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL99348920A 1999-01-11 1999-12-24 Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia PL348920A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19900545A DE19900545A1 (en) 1999-01-11 1999-01-11 Use of pyrimidine derivatives for the prophylaxis and therapy of cerebral ischemia

Publications (1)

Publication Number Publication Date
PL348920A1 true PL348920A1 (en) 2002-06-17

Family

ID=7893836

Family Applications (1)

Application Number Title Priority Date Filing Date
PL99348920A PL348920A1 (en) 1999-01-11 1999-12-24 Utilization of pyrimidine derivatives for preventing and treating cerebral ischaemia

Country Status (24)

Country Link
US (1) US6387912B1 (en)
EP (1) EP1140096A1 (en)
JP (1) JP2002534465A (en)
KR (1) KR20010101442A (en)
CN (1) CN1334732A (en)
AU (1) AU2433800A (en)
BG (1) BG105689A (en)
BR (1) BR9916887A (en)
CA (1) CA2359253A1 (en)
CZ (2) CZ20012484A3 (en)
DE (1) DE19900545A1 (en)
HK (1) HK1042649A1 (en)
HU (1) HUP0201149A3 (en)
ID (1) ID30022A (en)
IL (1) IL144146A0 (en)
MX (1) MXPA01006967A (en)
MY (1) MY133107A (en)
NO (1) NO20013409L (en)
NZ (1) NZ512767A (en)
PL (1) PL348920A1 (en)
SK (1) SK9692001A3 (en)
TR (1) TR200102008T2 (en)
WO (1) WO2000041695A1 (en)
ZA (1) ZA200105475B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19900673A1 (en) 1999-01-11 2000-07-13 Basf Ag Use of binding partners for 5-HT5 receptors for the treatment of neurodegenerative and neuropsychiatric disorders
US6988199B2 (en) * 2000-07-07 2006-01-17 Message Secure Secure and reliable document delivery
JP4548882B2 (en) * 1999-11-30 2010-09-22 興和創薬株式会社 4,5,6,7-tetrahydrothieno [2,3-c] pyridine compound
DE10031389A1 (en) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidine derivatives and their use for the prophylaxis and therapy of cerebral ischemia
DE10031390A1 (en) * 2000-07-03 2002-01-17 Knoll Ag Pyrimidine derivatives and their use for the prophylaxis and therapy of cerebral ischemia
DE10259382A1 (en) * 2002-12-18 2004-07-01 Abbott Gmbh & Co. Kg 3-Substituted 3,4-dihydro-thieno [2,3-d] pyrimidin-4-one derivatives, their preparation and use
WO2008138126A1 (en) * 2007-05-09 2008-11-20 Neuromed Pharmaceuticals Ltd. Bicyclic pyrimidine derivatives as calcium channel blockers
US8927718B2 (en) 2009-08-26 2015-01-06 Takeda Pharmaceutical Company Limited Fused heterocyclic ring derivative and use thereof
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
WO2021257863A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Pyrrolotriazine compounds as jak2 v617f inhibitors
SMT202500271T1 (en) 2020-07-02 2025-09-12 Incyte Corp Tricyclic urea compounds as jak2 v617f inhibitors
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
WO2022140231A1 (en) 2020-12-21 2022-06-30 Incyte Corporation Deazaguaine compounds as jak2 v617f inhibitors
AR125273A1 (en) 2021-02-25 2023-07-05 Incyte Corp SPIROCYCLIC LACTAMS AS JAK2 INHIBITORS V617F
CN119173514A (en) 2022-03-17 2024-12-20 因赛特公司 Tricyclic urea compounds as JAK2 V617F inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670560A (en) 1986-04-28 1987-06-02 Ortho Pharmaceutical Corporation Thienopyrimidine-2,4-dione derivatives and intermediates thereof
DE19636769A1 (en) 1996-09-10 1998-03-12 Basf Ag 3-Substituted pyrido [4 ', 3': 4,5] thieno [2,3-d] pyrimidine derivatives, their preparation and use
DE19724980A1 (en) 1997-06-13 1998-12-17 Basf Ag 3-Substituted 3,4-dihydro-thieno [2,3-d] pyrimidine derivatives, their preparation and use
DE19724979A1 (en) 1997-06-13 1998-12-17 Basf Ag 3-Substituted pyrido [3,4,5] thieno [2,3-d] pyrimidine derivatives, their preparation and use

Also Published As

Publication number Publication date
SK9692001A3 (en) 2002-05-09
US6387912B1 (en) 2002-05-14
JP2002534465A (en) 2002-10-15
CA2359253A1 (en) 2000-07-20
HUP0201149A3 (en) 2003-07-28
BG105689A (en) 2002-02-28
HK1042649A1 (en) 2002-08-23
ID30022A (en) 2001-11-01
CZ20012484A3 (en) 2002-05-15
KR20010101442A (en) 2001-11-14
HUP0201149A2 (en) 2002-07-29
CN1334732A (en) 2002-02-06
MXPA01006967A (en) 2002-04-10
CZ20012485A3 (en) 2002-04-17
IL144146A0 (en) 2002-05-23
MY133107A (en) 2007-10-31
AU2433800A (en) 2000-08-01
BR9916887A (en) 2001-11-20
NZ512767A (en) 2003-05-30
TR200102008T2 (en) 2001-12-21
EP1140096A1 (en) 2001-10-10
DE19900545A1 (en) 2000-07-13
NO20013409D0 (en) 2001-07-10
WO2000041695A1 (en) 2000-07-20
NO20013409L (en) 2001-08-30
ZA200105475B (en) 2002-10-03

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Legal Events

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