PL3495505T3 - Ocena ilościowa wydajności czapeczki informacyjnego rna - Google Patents
Ocena ilościowa wydajności czapeczki informacyjnego rnaInfo
- Publication number
- PL3495505T3 PL3495505T3 PL18207398.1T PL18207398T PL3495505T3 PL 3495505 T3 PL3495505 T3 PL 3495505T3 PL 18207398 T PL18207398 T PL 18207398T PL 3495505 T3 PL3495505 T3 PL 3495505T3
- Authority
- PL
- Poland
- Prior art keywords
- messenger rna
- quantitative assessment
- cap efficiency
- cap
- efficiency
- Prior art date
Links
- 108020004999 messenger RNA Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Chemical Kinetics & Catalysis (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784253P | 2013-03-14 | 2013-03-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3495505T3 true PL3495505T3 (pl) | 2025-01-13 |
Family
ID=50625146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18207398.1T PL3495505T3 (pl) | 2013-03-14 | 2014-03-14 | Ocena ilościowa wydajności czapeczki informacyjnego rna |
Country Status (15)
| Country | Link |
|---|---|
| US (4) | US10626439B2 (pl) |
| EP (2) | EP2971098B1 (pl) |
| JP (1) | JP2016515216A (pl) |
| CN (1) | CN105209633A (pl) |
| AU (1) | AU2014239264A1 (pl) |
| BR (1) | BR112015022141A2 (pl) |
| CA (1) | CA2903488A1 (pl) |
| DK (1) | DK2971098T3 (pl) |
| EA (1) | EA201591286A1 (pl) |
| ES (2) | ES2997341T3 (pl) |
| HU (1) | HUE069140T2 (pl) |
| MX (1) | MX2015011945A (pl) |
| PL (1) | PL3495505T3 (pl) |
| TR (1) | TR201901396T4 (pl) |
| WO (1) | WO2014152673A1 (pl) |
Families Citing this family (84)
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| KR102311614B1 (ko) | 2013-03-14 | 2021-10-08 | 샤이어 휴먼 지네틱 테라피즈 인크. | Cftr mrna 조성물 및 관련 방법 및 사용 |
| EA201591283A1 (ru) | 2013-03-14 | 2016-02-29 | Шир Хьюман Дженетик Терапис, Инк. | Количественная оценка эффективности кэп матричной рнк |
| EA201591229A1 (ru) | 2013-03-14 | 2016-01-29 | Шир Хьюман Дженетик Терапис, Инк. | Способы очистки матричной рнк |
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| ES2862412T3 (es) | 2015-10-14 | 2021-10-07 | Translate Bio Inc | Modificación de enzimas relacionados con el ARN para producción mejorada |
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| PL3458083T3 (pl) | 2016-05-18 | 2023-03-13 | Modernatx, Inc. | Polinukleotydy kodujące interleukinę-12 (il12) i ich zastosowania |
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| IL270631B2 (en) | 2017-05-16 | 2024-03-01 | Translate Bio Inc | Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr |
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| KR102773542B1 (ko) * | 2017-06-30 | 2025-02-25 | 코덱시스, 인코포레이티드 | T7 rna 폴리머라제 변이체 |
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| AU2019384557B2 (en) | 2018-11-21 | 2025-07-17 | Translate Bio, Inc. | Treatment of cystic fibrosis by delivery of nebulized mRNA encoding CFTR |
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| EP3986452A1 (en) | 2019-06-18 | 2022-04-27 | CureVac AG | Rotavirus mrna vaccine |
| WO2021028439A1 (en) | 2019-08-14 | 2021-02-18 | Curevac Ag | Rna combinations and compositions with decreased immunostimulatory properties |
| CA3155003A1 (en) | 2019-09-20 | 2021-03-25 | Translate Bio, Inc. | Mrna encoding engineered cftr |
| CN112626177A (zh) * | 2019-10-09 | 2021-04-09 | 华中科技大学 | 一种快速定量检测rna加帽效率的方法 |
| DE202021004130U1 (de) | 2020-02-04 | 2022-10-26 | Curevac Ag | Coronavirus-Vakzine |
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| MX2022015888A (es) * | 2020-06-26 | 2023-03-28 | Carisma Therapeutics Inc | Transfección de ácido ribonucleico mensajero (arnm) de células inmunitarias. |
| EP4172194A1 (en) | 2020-07-31 | 2023-05-03 | CureVac SE | Nucleic acid encoded antibody mixtures |
| CN113122596B (zh) * | 2020-08-20 | 2023-01-24 | 深圳市瑞吉生物科技有限公司 | 一种Cap2结构5′帽子类似物及其制备方法和应用 |
| WO2022043551A2 (en) | 2020-08-31 | 2022-03-03 | Curevac Ag | Multivalent nucleic acid based coronavirus vaccines |
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| MX2023007574A (es) | 2020-12-22 | 2023-09-29 | CureVac SE | "vacuna de arn contra variantes de sars-cov-2. |
| US20240299309A1 (en) | 2020-12-22 | 2024-09-12 | CureVac SE | Pharmaceutical composition comprising lipid-based carriers encapsulating rna for multidose administration |
| CA3170747A1 (en) | 2021-01-27 | 2022-08-04 | Moritz THRAN | Method of reducing the immunostimulatory properties of in vitro transcribed rna |
| EP4313152A1 (en) | 2021-03-26 | 2024-02-07 | GlaxoSmithKline Biologicals S.A. | Immunogenic compositions |
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| WO2022261050A1 (en) * | 2021-06-07 | 2022-12-15 | The University Of Massachusetts | Apparatus and method for continuous production of rna |
| IL309502A (en) | 2021-09-03 | 2024-02-01 | CureVac SE | Lipid nanoparticles for nucleic acid delivery involving phosphatidylserine |
| EP4416304A4 (en) * | 2021-10-14 | 2025-08-27 | Indevr Inc | NUCLEIC ACID ARRAYS FOR MRNA CHARACTERIZATION |
| CN115260264B (zh) * | 2022-02-28 | 2023-06-09 | 广州市恒诺康医药科技有限公司 | 用于rna加帽的化合物及其应用 |
| JP7699240B2 (ja) * | 2022-04-15 | 2025-06-26 | サーモ フィニガン リミテッド ライアビリティ カンパニー | Ｍｒｎａキャッピング効率の定量的モニタリング方法 |
| CN115896239A (zh) * | 2022-07-25 | 2023-04-04 | 四川康德赛医疗科技有限公司 | 一种rna修饰效率的定量方法、试剂盒及其应用 |
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| WO2024161314A1 (en) * | 2023-01-31 | 2024-08-08 | Seqirus Inc. | Capping assay |
| WO2024160936A1 (en) | 2023-02-03 | 2024-08-08 | Glaxosmithkline Biologicals Sa | Rna formulation |
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| CN116640833B (zh) * | 2023-06-01 | 2024-11-26 | 中国医学科学院医学生物学研究所 | 一种利用毛细管电泳技术自动化批量检测mRNA加帽率的方法 |
| CN116426610B (zh) * | 2023-06-08 | 2024-01-05 | 启辰生生物科技(珠海)有限公司 | 一种LC-MS法准确定量mRNA加帽效率的方法 |
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-
2014
- 2014-03-14 MX MX2015011945A patent/MX2015011945A/es unknown
- 2014-03-14 TR TR2019/01396T patent/TR201901396T4/tr unknown
- 2014-03-14 WO PCT/US2014/027602 patent/WO2014152673A1/en not_active Ceased
- 2014-03-14 CA CA2903488A patent/CA2903488A1/en not_active Abandoned
- 2014-03-14 DK DK14720376.4T patent/DK2971098T3/en active
- 2014-03-14 JP JP2016502491A patent/JP2016515216A/ja not_active Withdrawn
- 2014-03-14 EA EA201591286A patent/EA201591286A1/ru unknown
- 2014-03-14 BR BR112015022141A patent/BR112015022141A2/pt not_active IP Right Cessation
- 2014-03-14 EP EP14720376.4A patent/EP2971098B1/en active Active
- 2014-03-14 EP EP18207398.1A patent/EP3495505B1/en active Active
- 2014-03-14 ES ES18207398T patent/ES2997341T3/es active Active
- 2014-03-14 US US14/775,844 patent/US10626439B2/en active Active
- 2014-03-14 CN CN201480010108.7A patent/CN105209633A/zh active Pending
- 2014-03-14 AU AU2014239264A patent/AU2014239264A1/en not_active Withdrawn
- 2014-03-14 PL PL18207398.1T patent/PL3495505T3/pl unknown
- 2014-03-14 ES ES14720376T patent/ES2708562T3/es active Active
- 2014-03-14 HU HUE18207398A patent/HUE069140T2/hu unknown
-
2020
- 2020-01-16 US US16/744,985 patent/US11104934B2/en active Active
-
2021
- 2021-05-19 US US17/325,092 patent/US11920182B2/en active Active
-
2024
- 2024-02-01 US US18/430,247 patent/US12421538B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| ES2708562T3 (es) | 2019-04-10 |
| US20240417774A1 (en) | 2024-12-19 |
| US11920182B2 (en) | 2024-03-05 |
| EP3495505B1 (en) | 2024-09-11 |
| US11104934B2 (en) | 2021-08-31 |
| HUE069140T2 (hu) | 2025-02-28 |
| EP3495505C0 (en) | 2024-09-11 |
| EA201591286A1 (ru) | 2016-02-29 |
| US20210371900A1 (en) | 2021-12-02 |
| WO2014152673A1 (en) | 2014-09-25 |
| AU2014239264A1 (en) | 2015-08-27 |
| JP2016515216A (ja) | 2016-05-26 |
| TR201901396T4 (tr) | 2019-02-21 |
| US12421538B2 (en) | 2025-09-23 |
| EP2971098A1 (en) | 2016-01-20 |
| MX2015011945A (es) | 2015-12-01 |
| EP3495505A1 (en) | 2019-06-12 |
| BR112015022141A2 (pt) | 2017-08-29 |
| US10626439B2 (en) | 2020-04-21 |
| CA2903488A1 (en) | 2014-09-25 |
| DK2971098T3 (en) | 2019-02-18 |
| US20160002705A1 (en) | 2016-01-07 |
| CN105209633A (zh) | 2015-12-30 |
| EP2971098B1 (en) | 2018-11-21 |
| US20200318156A1 (en) | 2020-10-08 |
| ES2997341T3 (en) | 2025-02-17 |
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