PL3523639T3 - Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania - Google Patents

Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania

Info

Publication number
PL3523639T3
PL3523639T3 PL17858856.2T PL17858856T PL3523639T3 PL 3523639 T3 PL3523639 T3 PL 3523639T3 PL 17858856 T PL17858856 T PL 17858856T PL 3523639 T3 PL3523639 T3 PL 3523639T3
Authority
PL
Poland
Prior art keywords
methods
well
same
diagnostic test
detection reagents
Prior art date
Application number
PL17858856.2T
Other languages
English (en)
Inventor
Harvey Buck
Terry A. Beaty
Stacy Hunt Duvall
Original Assignee
F. Hoffmann-La Roche Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F. Hoffmann-La Roche Ag filed Critical F. Hoffmann-La Roche Ag
Publication of PL3523639T3 publication Critical patent/PL3523639T3/pl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/004—Enzyme electrodes mediator-assisted
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • C12Q1/005—Enzyme electrodes involving specific analytes or enzymes
    • C12Q1/006—Enzyme electrodes involving specific analytes or enzymes for glucose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3272—Test elements therefor, i.e. disposable laminated substrates with electrodes, reagent and channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3273—Devices therefor, e.g. test element readers, circuitry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3275—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction
    • G01N27/3276—Sensing specific biomolecules, e.g. nucleic acid strands, based on an electrode surface reaction being a hybridisation with immobilised receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
PL17858856.2T 2016-10-05 2017-08-16 Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania PL3523639T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201662404258P 2016-10-05 2016-10-05
PCT/US2017/047048 WO2018067235A1 (en) 2016-10-05 2017-08-16 Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same

Publications (1)

Publication Number Publication Date
PL3523639T3 true PL3523639T3 (pl) 2025-03-17

Family

ID=61831464

Family Applications (1)

Application Number Title Priority Date Filing Date
PL17858856.2T PL3523639T3 (pl) 2016-10-05 2017-08-16 Odczynniki wykrywające i układy elektrod do elementów diagnostycznych testów wieloanalitowych oraz sposoby ich zastosowania

Country Status (10)

Country Link
US (3) US11230727B2 (pl)
EP (2) EP3523639B1 (pl)
JP (2) JP2019529935A (pl)
KR (1) KR102372113B1 (pl)
CN (2) CN121955122A (pl)
CA (2) CA3250966A1 (pl)
ES (1) ES3009739T3 (pl)
PL (1) PL3523639T3 (pl)
TW (1) TWI661048B (pl)
WO (1) WO2018067235A1 (pl)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP4325222A3 (en) 2016-03-04 2024-05-01 Abbott Diabetes Care Inc. Nad(p)-dependent responsive enzymes, electrodes and sensors, and methods for making and using the same
JP2019529935A (ja) 2016-10-05 2019-10-17 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 多検体診断用試験エレメントのための検出試薬および電極配置、ならびにそれらを使用する方法
US10258295B2 (en) * 2017-05-09 2019-04-16 LifePod Solutions, Inc. Voice controlled assistance for monitoring adverse events of a user and/or coordinating emergency actions such as caregiver communication
US11250942B1 (en) * 2017-12-27 2022-02-15 Invoy Holdings Inc. Health monitoring and coaching system
US20210231598A1 (en) * 2018-05-18 2021-07-29 Nanobio Systems Inc. Detection of 1, 5-anhydroglucitol (1, 5-ag) in saliva
AU2020214230B2 (en) 2019-01-28 2023-03-02 Abbott Diabetes Care Inc. Analyte sensors employing multiple enzymes and methods associated therewith
CN113518584B (zh) 2019-01-28 2024-11-08 美国雅培糖尿病护理公司 检测肌酐的分析物传感器和感测方法
EP4574038A3 (en) 2019-01-28 2025-08-27 Abbott Diabetes Care, Inc. Analyte sensors and sensing methods featuring dual detection of glucose and ketones
CN114554955B (zh) * 2019-08-30 2024-12-03 美国雅培糖尿病护理公司 用于检测醇的分析物传感器和感测方法
CN214749932U (zh) 2020-01-14 2021-11-16 利多(香港)有限公司 一种电化学测试条
WO2022182344A1 (en) * 2021-02-25 2022-09-01 Nova Biomedical Corporation Disposable electrochemical biosensor based on nad(p)-dependent dehydrogenase and diaphorase
US11404062B1 (en) 2021-07-26 2022-08-02 LifePod Solutions, Inc. Systems and methods for managing voice environments and voice routines
US11410655B1 (en) 2021-07-26 2022-08-09 LifePod Solutions, Inc. Systems and methods for managing voice environments and voice routines
JP7781686B2 (ja) * 2022-03-17 2025-12-08 アークレイ株式会社 バイオセンサを用いた酸化還元酵素の電気化学的測定方法及びそれに用いるバイオセンサ
EP4779299A1 (en) * 2023-09-14 2026-07-22 Leadway (HK) Limited Measurement method for biosensor, and analysis system
TWI835702B (zh) * 2023-09-15 2024-03-11 立寶光電股份有限公司 設置於體外試劑檢測儀的檢測結構
GB2703866A (en) * 2024-10-15 2026-08-12 Early Health Ltd A sample testing device

Family Cites Families (201)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4008448A (en) 1975-10-03 1977-02-15 Polaroid Corporation Solenoid with selectively arrestible plunger movement
US4233029A (en) 1978-10-25 1980-11-11 Eastman Kodak Company Liquid transport device and method
US4225410A (en) 1978-12-04 1980-09-30 Technicon Instruments Corporation Integrated array of electrochemical sensors
US4323536A (en) 1980-02-06 1982-04-06 Eastman Kodak Company Multi-analyte test device
DE3228542A1 (de) 1982-07-30 1984-02-02 Siemens AG, 1000 Berlin und 8000 München Verfahren zur bestimmung der konzentration elektrochemisch umsetzbarer stoffe
US5509410A (en) 1983-06-06 1996-04-23 Medisense, Inc. Strip electrode including screen printing of a single layer
US5682884A (en) 1983-05-05 1997-11-04 Medisense, Inc. Strip electrode with screen printing
DE3321783A1 (de) 1983-06-16 1984-12-20 Boehringer Mannheim Gmbh, 6800 Mannheim Anordnung zum auswerten eines teststreifens
JPH0779694B2 (ja) 1985-07-09 1995-08-30 カドラント バイオリソ−シズ リミテツド 蛋白質および同類品の保護
DE3725766A1 (de) 1987-08-04 1989-02-16 Boehringer Mannheim Gmbh Testtraeger zur bestimmung eines analyten aus blut und verfahren zu seiner herstellung
US5128015A (en) 1988-03-15 1992-07-07 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
USRE36268E (en) 1988-03-15 1999-08-17 Boehringer Mannheim Corporation Method and apparatus for amperometric diagnostic analysis
US5108564A (en) 1988-03-15 1992-04-28 Tall Oak Ventures Method and apparatus for amperometric diagnostic analysis
DE68924026T3 (de) 1988-03-31 2008-01-10 Matsushita Electric Industrial Co., Ltd., Kadoma Biosensor und dessen herstellung.
DE3826922A1 (de) 1988-08-09 1990-02-22 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen bestimmung eines analyten mittels enzymatischer oxidation
US5053199A (en) 1989-02-21 1991-10-01 Boehringer Mannheim Corporation Electronically readable information carrier
DE3940010A1 (de) 1989-12-02 1991-06-06 Boehringer Mannheim Gmbh Verwendung eines schwer loeslichen salzes einer heteropolysaeure zur bestimmung eines analyts, entsprechendes bestimmungsverfahren sowie hierfuer geeignetes mittel
CA2069946C (en) 1989-12-15 1999-01-26 Klaus H. Pollmann Redox mediator reagent and biosensor
US5243516A (en) 1989-12-15 1993-09-07 Boehringer Mannheim Corporation Biosensing instrument and method
US4999632A (en) 1989-12-15 1991-03-12 Boehringer Mannheim Corporation Analog to digital conversion with noise reduction
US4963814A (en) 1989-12-15 1990-10-16 Boehringer Mannheim Corporation Regulated bifurcated power supply
US4999582A (en) 1989-12-15 1991-03-12 Boehringer Mannheim Corp. Biosensor electrode excitation circuit
US5508171A (en) 1989-12-15 1996-04-16 Boehringer Mannheim Corporation Assay method with enzyme electrode system
US5286362A (en) 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
DE4003194A1 (de) 1990-02-03 1991-08-08 Boehringer Mannheim Gmbh Verfahren und sensorelektrodensystem zur elektrochemischen bestimmung eines analyts oder einer oxidoreduktase sowie verwendung hierfuer geeigneter verbindungen
JP3251583B2 (ja) 1991-02-27 2002-01-28 ロシュ ダイアグノスティックス コーポレーション マイクロコンピュータ制御の器械と通信する方法
US5271895A (en) 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
DE4123348A1 (de) 1991-07-15 1993-01-21 Boehringer Mannheim Gmbh Elektrochemisches analysesystem
TW227042B (pl) 1991-12-19 1994-07-21 Eastman Kodak Co
ES2145054T3 (es) 1992-07-02 2000-07-01 Roche Diagnostics Corp Un reactivo estabilizado por sales de metal bivalente.
US5371687A (en) 1992-11-20 1994-12-06 Boehringer Mannheim Corporation Glucose test data acquisition and management system
CH685458A5 (de) 1993-03-01 1995-07-14 Disetronic Ag Sensorarray zur selektiven Feststellung oder Messung mindestens einer Stoffkomponente in einer wässerigen Lösung.
DE4311464A1 (de) 1993-04-08 1994-10-13 Boehringer Mannheim Gmbh Verfahren zur kolorimetrischen Bestimmung eines Analyten mit einer PQQ-abhängigen Dehydrogenase
US5385846A (en) 1993-06-03 1995-01-31 Boehringer Mannheim Corporation Biosensor and method for hematocrit determination
EP0702789B8 (en) 1993-06-08 2006-06-14 Roche Diagnostics Operations, Inc. Biosensing meter which detects proper electrode engagement and distinguishes sample and check strips
US5405511A (en) 1993-06-08 1995-04-11 Boehringer Mannheim Corporation Biosensing meter with ambient temperature estimation method and system
US5366609A (en) 1993-06-08 1994-11-22 Boehringer Mannheim Corporation Biosensing meter with pluggable memory key
US5352351A (en) 1993-06-08 1994-10-04 Boehringer Mannheim Corporation Biosensing meter with fail/safe procedures to prevent erroneous indications
ES2154249T3 (es) 1993-06-21 2001-12-16 Roche Diagnostics Corp Estabilizador de reactivos de diagnostico.
US5413690A (en) 1993-07-23 1995-05-09 Boehringer Mannheim Corporation Potentiometric biosensor and the method of its use
US5526111A (en) 1993-08-31 1996-06-11 Boehringer Mannheim Corporation Method and apparatus for calculating a coagulation characteristic of a sample of blood a blood fraction or a control
US5393615A (en) 1994-02-03 1995-02-28 Miles Inc. Mediators suitable for the electrochemical regeneration of NADH, NADPH or analogs thereof
US5762770A (en) 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
US5437999A (en) 1994-02-22 1995-08-01 Boehringer Mannheim Corporation Electrochemical sensor
DE19521019A1 (de) 1995-06-13 1996-12-19 Boehringer Mannheim Gmbh Verfahren und Mittel zur gleichzeitigen kolorimetrischen und elektrochemischen Messung eines Analyten
US5628890A (en) 1995-09-27 1997-05-13 Medisense, Inc. Electrochemical sensor
JP3365184B2 (ja) 1996-01-10 2003-01-08 松下電器産業株式会社 バイオセンサ
WO1997048979A1 (en) 1996-06-17 1997-12-24 Mercury Diagnostics Inc. Electrochemical test device and related methods
DE19629655A1 (de) 1996-07-23 1998-01-29 Boehringer Mannheim Gmbh Diagnostischer Testträger und Verfahren zur Bestimmung eines Analyts mit dessen Hilfe
DE19639169A1 (de) 1996-09-24 1998-04-02 Boehringer Mannheim Gmbh Redoxaktive Verbindungen und deren Anwendung
EP1258728B1 (en) 1996-10-30 2012-05-30 F. Hoffmann-La Roche AG Synchronized analyte testing system
US5801006A (en) 1997-02-04 1998-09-01 Specialty Assays, Inc. Use of NADPH and NADH analogs in the measurement of enzyme activities and metabolites
AU6157898A (en) 1997-02-06 1998-08-26 E. Heller & Company Small volume (in vitro) analyte sensor
US5798031A (en) * 1997-05-12 1998-08-25 Bayer Corporation Electrochemical biosensor
US5948695A (en) 1997-06-17 1999-09-07 Mercury Diagnostics, Inc. Device for determination of an analyte in a body fluid
US6054039A (en) 1997-08-18 2000-04-25 Shieh; Paul Determination of glycoprotein and glycosylated hemoglobin in blood
US6001239A (en) 1998-09-30 1999-12-14 Mercury Diagnostics, Inc. Membrane based electrochemical test device and related methods
US6144922A (en) 1997-10-31 2000-11-07 Mercury Diagnostics, Incorporated Analyte concentration information collection and communication system
WO1999023597A2 (en) 1997-10-31 1999-05-14 Amira Medical Analyte concentration information collection and communication s ystem
DE19753849A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytisches Testelement mit sich verjüngendem Kapillarkanal
DE19753847A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Analytisches Testelement mit Kapillarkanal
NZ524206A (en) 1997-12-04 2004-05-28 Roche Diagnostics Corp Instrument for determining the concentration of a medically significant component of a sample
DE19753848A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Modifikation von Oberflächen zur Steigerung der Oberflächenspannung
DE19753850A1 (de) 1997-12-04 1999-06-10 Roche Diagnostics Gmbh Probennahmevorrichtung
US5997817A (en) 1997-12-05 1999-12-07 Roche Diagnostics Corporation Electrochemical biosensor test strip
JP2001527216A (ja) 1997-12-19 2001-12-25 アミラ メディカル エンボス加工されたテストストリップシステム
US7407811B2 (en) 1997-12-22 2008-08-05 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC excitation
JP3260739B2 (ja) 1997-12-22 2002-02-25 ロシュ ダイアグノスティックス コーポレーション 生物学的流体の医学的に有意な成分の濃度を測定する装置および方法
US7494816B2 (en) 1997-12-22 2009-02-24 Roche Diagnostic Operations, Inc. System and method for determining a temperature during analyte measurement
US7390667B2 (en) 1997-12-22 2008-06-24 Roche Diagnostics Operations, Inc. System and method for analyte measurement using AC phase angle measurements
US5975153A (en) 1998-02-13 1999-11-02 Roche Diagnostics Corporation Capillary fill test device with improved fluid delivery
DE19814219A1 (de) 1998-03-31 1999-10-07 Roche Diagnostics Gmbh Verfahren zur Kontrolle der Insulinmedikation
US6505059B1 (en) 1998-04-06 2003-01-07 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US7899518B2 (en) 1998-04-06 2011-03-01 Masimo Laboratories, Inc. Non-invasive tissue glucose level monitoring
DE19815684A1 (de) 1998-04-08 1999-10-14 Roche Diagnostics Gmbh Verfahren zur Herstellung von analytischen Hilfsmitteln
US6945955B1 (en) 1998-05-20 2005-09-20 Disetronic Licensing Ag Sensor system including a port body
DE19840952C1 (de) 1998-09-08 2000-03-23 Roche Diagnostics Gmbh LC-Display mit Ausfallkontrolle
US6338790B1 (en) * 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
DE19849008A1 (de) 1998-10-23 2000-04-27 Roche Diagnostics Gmbh Spreitschichten, Netzmittel zu ihrer Herstellung und deren Verwendung in Teststreifen
US6380380B1 (en) 1999-01-04 2002-04-30 Specialty Assays, Inc. Use of nicotinamide adenine dinucleotide (NAD) and nicotinamide adenine dinucliotide phosphate (NADP) analogs to measure enzyme activities metabolites and substrates
US7208119B1 (en) 2000-03-01 2007-04-24 Roche Diagnostics Operations, Inc. Hospital meter system
US7045054B1 (en) 1999-09-20 2006-05-16 Roche Diagnostics Corporation Small volume biosensor for continuous analyte monitoring
DE19945828B4 (de) 1999-09-24 2011-06-01 Roche Diagnostics Gmbh Analysenelement und Verfahren zur Bestimmung eines Analyten in Flüssigkeit
US7276146B2 (en) 2001-11-16 2007-10-02 Roche Diagnostics Operations, Inc. Electrodes, methods, apparatuses comprising micro-electrode arrays
US6662439B1 (en) 1999-10-04 2003-12-16 Roche Diagnostics Corporation Laser defined features for patterned laminates and electrodes
US6767440B1 (en) 2001-04-24 2004-07-27 Roche Diagnostics Corporation Biosensor
US7073246B2 (en) 1999-10-04 2006-07-11 Roche Diagnostics Operations, Inc. Method of making a biosensor
US6319719B1 (en) 1999-10-28 2001-11-20 Roche Diagnostics Corporation Capillary hematocrit separation structure and method
US6413395B1 (en) 1999-12-16 2002-07-02 Roche Diagnostics Corporation Biosensor apparatus
US6627057B1 (en) 1999-12-23 2003-09-30 Roche Diagnostic Corporation Microsphere containing sensor
US6780296B1 (en) 1999-12-23 2004-08-24 Roche Diagnostics Corporation Thermally conductive sensor
US6562210B1 (en) 1999-12-30 2003-05-13 Roche Diagnostics Corporation Cell for electrochemical anaylsis of a sample
US6451264B1 (en) 2000-01-28 2002-09-17 Roche Diagnostics Corporation Fluid flow control in curved capillary channels
US6406672B1 (en) 2000-01-28 2002-06-18 Roche Diagnostics Plasma retention structure providing internal flow
US20030146113A1 (en) 2000-02-21 2003-08-07 Volker Unkrig Electrochemical sensor for determining blood clotting, corresponding system for measuring blood clotting and method for determining blood clotting
US6858433B1 (en) 2000-04-03 2005-02-22 Roche Diagnostics Operations, Inc. Biosensor electromagnetic noise cancellation
US6413213B1 (en) 2000-04-18 2002-07-02 Roche Diagnostics Corporation Subscription based monitoring system and method
US6428664B1 (en) 2000-06-19 2002-08-06 Roche Diagnostics Corporation Biosensor
DE10032015A1 (de) 2000-07-01 2002-01-10 Roche Diagnostics Gmbh Testelement-Analysegerät
US6488828B1 (en) 2000-07-20 2002-12-03 Roche Diagnostics Corporation Recloseable biosensor
AU1596602A (en) 2000-10-27 2002-05-06 Peter Kratzsch Variants of soluble pyrroloquinoline quinone-dependent glucose dehydrogenase
US6814843B1 (en) 2000-11-01 2004-11-09 Roche Diagnostics Corporation Biosensor
US6540890B1 (en) 2000-11-01 2003-04-01 Roche Diagnostics Corporation Biosensor
US6447657B1 (en) 2000-12-04 2002-09-10 Roche Diagnostics Corporation Biosensor
AT410601B (de) 2000-12-29 2003-06-25 Hoffmann La Roche Sensor zur lumineszenz-optischen bestimmung eines analyten sowie reagens, das nach dem fret-prinzip arbeitet
DE10119036C1 (de) 2001-04-18 2002-12-12 Disetronic Licensing Ag Tauchsensor zur Messung der Konzentration eines Analyten mit Hilfe einer Oxidase
US8226814B2 (en) * 2001-05-11 2012-07-24 Abbott Diabetes Care Inc. Transition metal complexes with pyridyl-imidazole ligands
US7473398B2 (en) 2001-05-25 2009-01-06 Roche Diagnostics Operations, Inc. Biosensor
US6814844B2 (en) 2001-08-29 2004-11-09 Roche Diagnostics Corporation Biosensor with code pattern
US6984307B2 (en) 2001-10-05 2006-01-10 Stephen Eliot Zweig Dual glucose-hydroxybutyrate analytical sensors
US6755949B1 (en) 2001-10-09 2004-06-29 Roche Diagnostics Corporation Biosensor
US7018843B2 (en) 2001-11-07 2006-03-28 Roche Diagnostics Operations, Inc. Instrument
US20030116447A1 (en) 2001-11-16 2003-06-26 Surridge Nigel A. Electrodes, methods, apparatuses comprising micro-electrode arrays
AU2003201901B2 (en) 2001-12-28 2006-09-21 Arkray, Inc. Method of colorimetry and reagent for use therein
US6863800B2 (en) * 2002-02-01 2005-03-08 Abbott Laboratories Electrochemical biosensor strip for analysis of liquid samples
US6866758B2 (en) 2002-03-21 2005-03-15 Roche Diagnostics Corporation Biosensor
US6743635B2 (en) * 2002-04-25 2004-06-01 Home Diagnostics, Inc. System and methods for blood glucose sensing
US20040040868A1 (en) * 2002-06-19 2004-03-04 Denuzzio John D. Microfabricated sensor arrays for multi-component analysis in minute volumes
US9017544B2 (en) 2002-10-04 2015-04-28 Roche Diagnostics Operations, Inc. Determining blood glucose in a small volume sample receiving cavity and in a short time period
EP1467206A1 (en) 2003-04-08 2004-10-13 Roche Diagnostics GmbH Biosensor system
KR100785670B1 (ko) 2003-06-20 2007-12-14 에프. 호프만-라 로슈 아게 폭이 좁은 균질한 시약 시트립을 제조하는 방법 및 시약
US7488601B2 (en) 2003-06-20 2009-02-10 Roche Diagnostic Operations, Inc. System and method for determining an abused sensor during analyte measurement
US7452457B2 (en) 2003-06-20 2008-11-18 Roche Diagnostics Operations, Inc. System and method for analyte measurement using dose sufficiency electrodes
US8148164B2 (en) 2003-06-20 2012-04-03 Roche Diagnostics Operations, Inc. System and method for determining the concentration of an analyte in a sample fluid
US7597793B2 (en) 2003-06-20 2009-10-06 Roche Operations Ltd. System and method for analyte measurement employing maximum dosing time delay
US8506775B2 (en) 2003-06-20 2013-08-13 Roche Diagnostics Operations, Inc. Devices and methods relating to electrochemical biosensors
US8071030B2 (en) * 2003-06-20 2011-12-06 Roche Diagnostics Operations, Inc. Test strip with flared sample receiving chamber
MXPA06001719A (es) 2003-08-11 2006-05-19 Codexis Inc Polipeptidos de glucosa deshidrogenasa mejorados, y polinucleotidos relacionados.
ES2341963T3 (es) 2003-09-30 2010-06-30 F. Hoffmann-La Roche Ag Detector con biocompatibilidad mejorada.
DE10346417A1 (de) 2003-10-07 2005-06-02 Roche Diagnostics Gmbh Analytisches Testelement umfassend ein Netzwerk zur Bildung eines Kapillarkanals
DE102004007983A1 (de) 2004-02-18 2005-09-08 Roche Diagnostics Gmbh Testelement mit Einschicht-Reaktionsfilm
AU2005201576B2 (en) 2004-05-07 2010-06-24 F. Hoffmann-La Roche Ag Process and device for producing an analytical tape for liquid samples
US7569126B2 (en) 2004-06-18 2009-08-04 Roche Diagnostics Operations, Inc. System and method for quality assurance of a biosensor test strip
US7601299B2 (en) 2004-06-18 2009-10-13 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7556723B2 (en) 2004-06-18 2009-07-07 Roche Diagnostics Operations, Inc. Electrode design for biosensor
GB2417323A (en) 2004-08-17 2006-02-22 Oxford Biosensors Ltd A method of operating an electrochemical sensor by applying a time variable potential between the electrodes.
US7291107B2 (en) 2004-08-26 2007-11-06 Roche Diagnostics Operations, Inc. Insulin bolus recommendation system
ATE369562T1 (de) * 2004-09-09 2007-08-15 Analyticon Biotechnologies Ag Lateralflussmessvorrichtung und messverfahren für analyten
DE102005035461A1 (de) 2005-07-28 2007-02-15 Roche Diagnostics Gmbh Stabile NAD/NADH-Derivate
JP4786451B2 (ja) 2005-07-28 2011-10-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト Ｎａｄ／ｎａｄｈの安定化
CN103048442B (zh) * 2005-09-30 2015-04-08 拜尔健康护理有限责任公司 门控伏特安培法
US7429865B2 (en) 2005-10-05 2008-09-30 Roche Diagnostics Operations, Inc. Method and system for error checking an electrochemical sensor
CA2564666A1 (en) 2005-10-25 2007-04-25 F. Hoffmann-La Roche Ag Fluorescence spectroscopy in absorbing media
US7638095B2 (en) 2006-02-10 2009-12-29 Roche Diagnostics Operations, Inc. Personal portable blood glucose meter with replaceable cartridge of test strips
PL3246402T3 (pl) 2006-04-13 2020-10-19 F. Hoffmann-La Roche Ag Ulepszone mutanty rozpuszczalnej dehydrogenazy glukozowej zależnej od pirolochinolinochinonu
US7951271B2 (en) 2006-06-12 2011-05-31 David Brent Thompson System for recovering oil from used automobile tires
BRPI0717430A2 (pt) * 2006-09-22 2013-11-12 Bayer Healthcare Llc Sistema de biossensor tendo estabilidade e desempenho de hematócritos maiores
US7312042B1 (en) 2006-10-24 2007-12-25 Abbott Diabetes Care, Inc. Embossed cell analyte sensor and methods of manufacture
TWI385472B (zh) 2006-11-17 2013-02-11 Hon Hai Prec Ind Co Ltd 鏡頭模組及鏡頭模組調焦機構
US7751864B2 (en) 2007-03-01 2010-07-06 Roche Diagnostics Operations, Inc. System and method for operating an electrochemical analyte sensor
EP2022859A1 (de) 2007-08-01 2009-02-11 Roche Diagnostics GmbH Verfahren und Vorrichtung zur Bestimmung der Konzentration eines Analyten mittels Fluoreszenzmessung
MX2010003205A (es) * 2007-09-24 2010-04-09 Bayer Healthcare Llc Sensores de prueba multi-region y multi-potenciales, metodos y sistemas.
KR100980115B1 (ko) 2008-01-07 2010-09-07 서울대학교산학협력단 발광 다이오드 코팅 방법
US7678250B2 (en) 2008-01-22 2010-03-16 Home Diagnostics, Inc. Reagent compositions for use in electrochemical detection
EP2090996A1 (en) 2008-02-16 2009-08-19 Roche Diagnostics GmbH Medical device
EP2093284A1 (de) 2008-02-19 2009-08-26 F.Hoffmann-La Roche Ag Stabilisierung von Dehydrogenasen mit stabilen Coenzymen
US8008037B2 (en) 2008-03-27 2011-08-30 Roche Diagnostics Operations, Inc. Matrix composition with alkylphenazine quaternary salt and a nitrosoaniline
CA2750474C (en) 2009-02-19 2017-07-25 F. Hoffmann-La Roche Ag Fast reaction kinetics of enzymes having low activity in dry chemistry layers
EP2398909B1 (de) 2009-02-19 2015-07-22 F. Hoffmann-La Roche AG Schnelle reaktionskinetik von enzymen mit niedriger aktivität in trockenen chemieschichten
EP2226008A1 (de) 2009-02-19 2010-09-08 Roche Diagnostics GmbH Verfahren zur Herstellung eines analytischen Magazins
CN102325496B (zh) 2009-02-19 2015-10-07 霍夫曼-拉罗奇有限公司 分析辅助工具的节省空间的储存
EP2435579A4 (en) 2009-05-29 2013-04-17 Univ Mcmaster BIOSENSORS WITH INK JET PRINTED BIOMOLECULENTAL CARPETS AND APPLICATIONS THEREOF
US9218453B2 (en) 2009-06-29 2015-12-22 Roche Diabetes Care, Inc. Blood glucose management and interface systems and methods
JP5544423B2 (ja) 2009-07-27 2014-07-09 エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト Ｎ置換ピリジニウム化合物の調製のための方法及び物質
WO2011012269A2 (en) 2009-07-27 2011-02-03 Roche Diagnostics Gmbh Method and substances for preparation of n-substituted pyridinium compounds
CN102471793B (zh) 2009-07-27 2014-04-30 霍夫曼-拉罗奇有限公司 Carba-nad的酶促合成
EP2292751A1 (de) 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
US20110048972A1 (en) * 2009-08-31 2011-03-03 Lifescan Scotland Limited Multi-analyte test strip with shared counter/reference electrode and inline electrode configuration
US8357276B2 (en) * 2009-08-31 2013-01-22 Abbott Diabetes Care Inc. Small volume test strips with large sample fill ports, supported test strips, and methods of making and using same
MX2012014620A (es) * 2010-06-30 2013-02-07 Hoffmann La Roche Metodos para fabricar una tira reactiva de biosensor dual.
US20130092536A1 (en) 2010-07-23 2013-04-18 Roche Diagnostics Operations, Inc. Zwitterion buffer containing compositions and uses in electroanalytical methods
US8431408B2 (en) 2010-10-15 2013-04-30 Roche Diagnostics Operations, Inc. Handheld diabetes managing device with light pipe for enhanced illumination
US9717452B2 (en) 2010-12-30 2017-08-01 Roche Diabetes Care, Inc. Handheld medical diagnostic devices with lancing speed control
US8852123B2 (en) 2010-12-30 2014-10-07 Roche Diagnostics Operations, Inc. Handheld medical diagnostic devices housing with sample transfer
US8771793B2 (en) 2011-04-15 2014-07-08 Roche Diagnostics Operations, Inc. Vacuum assisted slot die coating techniques
US9754708B2 (en) 2011-07-29 2017-09-05 Roche Diabetes Care, Inc. Encoded biosensors and methods of manufacture and use thereof
US8888973B2 (en) 2011-07-29 2014-11-18 Roche Diagnostics Operations, Inc. Encoded biosensors and methods of manufacture and use thereof
EP2760825B1 (de) 2011-09-28 2016-09-14 F.Hoffmann-La Roche Ag Azomediatoren
EP2636750A1 (en) 2012-03-06 2013-09-11 Roche Diagniostics GmbH Compatible solute ectoine as well as derivatives thereof for enzyme stabilization
US8992750B1 (en) 2012-07-02 2015-03-31 Roche Diagnostics Operations, Inc. Biosensor and methods for manufacturing
KR20150052868A (ko) 2012-09-06 2015-05-14 에프. 호프만-라 로슈 아게 개선된 매트릭스 안정성 조성물 및 방법
US8921061B2 (en) * 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Reagent materials and associated test elements
US8920628B2 (en) 2012-11-02 2014-12-30 Roche Diagnostics Operations, Inc. Systems and methods for multiple analyte analysis
EP2770064A1 (de) * 2013-02-22 2014-08-27 F. Hoffmann-La Roche AG Hocheffiziente Herstellung von Blutglucose-Teststreifen
WO2014140718A2 (en) 2013-03-11 2014-09-18 Lincoln Global, Inc. Auto steering in a weld joint
CA2949909C (en) 2013-03-15 2019-10-01 F. Hoffmann-La Roche Ag Methods of scaling data used to construct biosensor algorithms as well as devices, apparatuses and systems incorporating the same
KR101771829B1 (ko) 2013-03-15 2017-08-25 에프. 호프만-라 로슈 아게 분석물질을 전기화학적으로 측정하는 디스크립터-기반 방법들 및 그것을 통합한 디바이스들, 장치들 및 시스템들
JP6352954B2 (ja) 2013-03-15 2018-07-04 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 電気化学的な分析物測定において回復パルスからの情報を使用する方法およびデバイス、装置とそれらを組み込むシステム
CA2900885C (en) 2013-03-15 2017-12-19 F. Hoffmann-La Roche Ag Methods of electrochemically measuring an analyte with a test sequence having a pulsed dc block as well as devices, apparatuses and systems incorporating the same
JP6412027B2 (ja) 2013-03-15 2018-10-24 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 分析物のフェイルセーフ電気化学的測定の方法、並びにそれを組み込んだデバイス、装置及びシステム
EP2972269B1 (en) * 2013-03-15 2018-07-11 Roche Diabetes Care GmbH Methods of detecting high antioxidant levels during electrochemical measurements and failsafing an analyte concentration therefrom
WO2015057933A1 (en) 2013-10-16 2015-04-23 Asset Intertech, Inc. Method of presenting trace data with improved efficiency by using hosted formatted output commands
TWI588286B (zh) 2013-11-26 2017-06-21 烏翠泰克股份有限公司 經改良的電漿強化原子層沉積方法、周期及裝置
CN106164054B (zh) * 2014-04-14 2019-05-07 豪夫迈·罗氏有限公司 吩嗪介导剂
KR102190203B1 (ko) 2014-06-05 2020-12-14 에프. 호프만-라 로슈 아게 테스트 엘리먼트 무결성을 위한 전극 배열체들
JP6639479B2 (ja) * 2014-08-25 2020-02-05 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 干渉補償型の２電極テストストリップ
JP6526193B2 (ja) * 2014-11-03 2019-06-05 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 電気化学的テストエレメントのための電極配置およびその使用方法
GB201507508D0 (en) * 2015-04-30 2015-06-17 Inside Biometrics Ltd Electrochemical Test Device
GB201507510D0 (en) * 2015-04-30 2015-06-17 Inside Biometrics Ltd Electrochemical Test Device
CN108882893A (zh) 2016-03-29 2018-11-23 豪夫迈·罗氏有限公司 操作用于接收分析物数据的接收器的方法，接收器和计算机程序产品
JP2019529935A (ja) 2016-10-05 2019-10-17 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 多検体診断用試験エレメントのための検出試薬および電極配置、ならびにそれらを使用する方法

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