PL352374A1 - Inhibitors of integrine o v beta 6 - Google Patents

Inhibitors of integrine o v beta 6

Info

Publication number: PL352374A1
Authority: PL; Poland
Prior art keywords: integrine; inhibitors; beta
Prior art date: 1999-06-26

Application number

PL00352374A

Inventor

Alfred Jonczyk

Beate Diefenbach

Ulrich Groth

Gunther Zischinsky

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-26

Filing date

2000-06-13

Publication date

2003-08-25

2000-06-13 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2003-08-25 Publication of PL352374A1 publication Critical patent/PL352374A1/en

Links

239000003112 inhibitor Substances 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Physical Education & Sports Medicine (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Orthopedic Medicine & Surgery (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Hematology (AREA)
Neurology (AREA)
Communicable Diseases (AREA)
Heart & Thoracic Surgery (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Oncology (AREA)
Diabetes (AREA)
Urology & Nephrology (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

PL00352374A 1999-06-26 2000-06-13 Inhibitors of integrine o v beta 6 PL352374A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19929410A DE19929410A1 (en)	1999-06-26	1999-06-26	New octapepide compounds as alpha v beta 6 integrin inhibitors useful for treating and diagnosing heart disease, tumors, osteoporosis, fibrosis, inflammation, infection and psoriasis
PCT/EP2000/005404 WO2001000660A1 (en)	1999-06-26	2000-06-13	INHIBITORS OF THE INTEGRIN αvβ¿6?

Publications (1)

Publication Number	Publication Date
PL352374A1 true PL352374A1 (en)	2003-08-25

Family

ID=7912712

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL00352374A PL352374A1 (en)	1999-06-26	2000-06-13	Inhibitors of integrine o v beta 6

Country Status (17)

Country	Link
EP (1)	EP1189930A1 (en)
JP (1)	JP2003503422A (en)
KR (1)	KR20020015704A (en)
CN (1)	CN1358195A (en)
AR (1)	AR024472A1 (en)
AU (1)	AU771099B2 (en)
BR (1)	BR0011954A (en)
CA (1)	CA2377224A1 (en)
CZ (1)	CZ20014484A3 (en)
DE (1)	DE19929410A1 (en)
HU (1)	HUP0201729A3 (en)
MX (1)	MXPA01013247A (en)
NO (1)	NO20016341L (en)
PL (1)	PL352374A1 (en)
SK (1)	SK18722001A3 (en)
WO (1)	WO2001000660A1 (en)
ZA (1)	ZA200200673B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6972296B2 (en)	1999-05-07	2005-12-06	Encysive Pharmaceuticals Inc.	Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
DE502004007051D1 (en) *	2003-02-06	2008-06-19	Merck Patent Gmbh	PEPTIDIC SULFONAMIDE
GB0520068D0 (en)	2005-10-03	2005-11-09	Cancer Res Technology	av peptide ligand
EP2064244B1 (en)	2006-08-03	2019-06-05	MedImmune Limited	ANTIBODIES DIRECTED TO alphaVbeta6 AND USES THEREOF
SI3535397T1 (en)	2016-11-01	2022-04-29	Arrowhead Pharmaceuticals, Inc.	Alpha-v beta-6 integrin ligands and uses thereof
WO2019089765A1 (en)	2017-11-01	2019-05-09	Arrowhead Pharmcaceuticals, Inc.	Integrin ligands and uses thereof
JP2024516096A (en)	2021-04-08	2024-04-12	アローヘッドファーマシューティカルズインコーポレイテッド	RNAi agents for inhibiting expression of receptor for advanced glycation end products, compositions thereof, and methods of use

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2029392A (en) *	1991-05-14	1992-12-30	Board Of Regents Of The University Of Oklahoma, The	Peptide inhibitors of inflammation
ATE511850T1 (en) *	1997-08-08	2011-06-15	Univ California	TREATMENT OF BLADDER FIBROSIS WITH ANTIBODIES TO ALPHA-V BETA-6 INTEGRIN
CZ20012212A3 (en) *	1998-12-19	2001-09-12	Merck Patent Gmbh	Peptidic compound, use thereof and pharmaceutical preparation in which the compound is comprised

1999
- 1999-06-26 DE DE19929410A patent/DE19929410A1/en not_active Withdrawn
2000
- 2000-06-13 MX MXPA01013247A patent/MXPA01013247A/en unknown
- 2000-06-13 CN CN00809493A patent/CN1358195A/en active Pending
- 2000-06-13 KR KR1020017016580A patent/KR20020015704A/en not_active Withdrawn
- 2000-06-13 CZ CZ20014484A patent/CZ20014484A3/en unknown
- 2000-06-13 BR BR0011954-7A patent/BR0011954A/en not_active IP Right Cessation
- 2000-06-13 EP EP00949177A patent/EP1189930A1/en not_active Withdrawn
- 2000-06-13 WO PCT/EP2000/005404 patent/WO2001000660A1/en not_active Ceased
- 2000-06-13 PL PL00352374A patent/PL352374A1/en unknown
- 2000-06-13 JP JP2001507066A patent/JP2003503422A/en active Pending
- 2000-06-13 HU HU0201729A patent/HUP0201729A3/en unknown
- 2000-06-13 SK SK1872-2001A patent/SK18722001A3/en unknown
- 2000-06-13 CA CA002377224A patent/CA2377224A1/en not_active Abandoned
- 2000-06-13 AU AU62630/00A patent/AU771099B2/en not_active Ceased
- 2000-06-23 AR ARP000103177A patent/AR024472A1/en not_active Application Discontinuation
2001
- 2001-12-21 NO NO20016341A patent/NO20016341L/en not_active Application Discontinuation
2002
- 2002-01-24 ZA ZA200200673A patent/ZA200200673B/en unknown

Also Published As

Publication number	Publication date
AU6263000A (en)	2001-01-31
AR024472A1 (en)	2002-10-02
JP2003503422A (en)	2003-01-28
ZA200200673B (en)	2003-04-24
CZ20014484A3 (en)	2002-04-17
EP1189930A1 (en)	2002-03-27
NO20016341L (en)	2002-02-25
KR20020015704A (en)	2002-02-28
DE19929410A1 (en)	2000-12-28
CN1358195A (en)	2002-07-10
HUP0201729A3 (en)	2005-01-28
HUP0201729A2 (en)	2002-08-28
CA2377224A1 (en)	2001-01-04
MXPA01013247A (en)	2002-07-02
SK18722001A3 (en)	2002-05-09
BR0011954A (en)	2002-05-07
AU771099B2 (en)	2004-03-11
WO2001000660A1 (en)	2001-01-04
NO20016341D0 (en)	2001-12-21

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HUP0201610A3 (en)	2003-03-28	Derivatives of 4'-demycarosyl-8a-aza-8a-homotylosin
GB9700233D0 (en)	1997-02-26	Use of glycosidase inhibitors
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