PL352758A1 - Odpowiedź immunologiczna blokująca na obcy antygen stosując antagonistę, który wiąże się z CD 20 - Google Patents
Odpowiedź immunologiczna blokująca na obcy antygen stosując antagonistę, który wiąże się z CD 20Info
- Publication number
- PL352758A1 PL352758A1 PL00352758A PL35275800A PL352758A1 PL 352758 A1 PL352758 A1 PL 352758A1 PL 00352758 A PL00352758 A PL 00352758A PL 35275800 A PL35275800 A PL 35275800A PL 352758 A1 PL352758 A1 PL 352758A1
- Authority
- PL
- Poland
- Prior art keywords
- antagonist
- binds
- immune response
- foreign antigen
- blocking immune
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2887—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD20
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39541—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against normal tissues, cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
- A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
- A61K51/1027—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody against receptors, cell-surface antigens or cell-surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14440599P | 1999-07-12 | 1999-07-12 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL352758A1 true PL352758A1 (pl) | 2003-09-08 |
| PL201086B1 PL201086B1 (pl) | 2009-03-31 |
Family
ID=22508442
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL352758A PL201086B1 (pl) | 1999-07-12 | 2000-07-10 | Zastosowanie przeciwciał wiążących się z antygenem CD20 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US20100003252A1 (pl) |
| EP (1) | EP1216056A1 (pl) |
| JP (1) | JP2003528805A (pl) |
| KR (2) | KR20020027490A (pl) |
| CN (2) | CN101264324A (pl) |
| AU (2) | AU778863B2 (pl) |
| BR (1) | BR0013201A (pl) |
| CA (1) | CA2379274A1 (pl) |
| HK (1) | HK1047702A1 (pl) |
| HU (1) | HUP0202238A3 (pl) |
| IL (1) | IL147547A0 (pl) |
| MX (1) | MXPA02000419A (pl) |
| NO (1) | NO20020128L (pl) |
| NZ (1) | NZ516491A (pl) |
| PL (1) | PL201086B1 (pl) |
| WO (1) | WO2001003734A1 (pl) |
| ZA (1) | ZA200200272B (pl) |
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| BRPI0315295C1 (pt) | 2002-10-17 | 2021-05-25 | Genmab As | anticorpo monoclonal humano isolado, célula hospedeira procariótica, composição farmacêutica, molécula biespecífica, usos de um anticorpo, métodos in vitro de detectar a presença de antígeno de cd20 ou uma célula que expressa cd20 em uma amostra, kit, e, vetor de expressão |
| TWI335821B (en) | 2002-12-16 | 2011-01-11 | Genentech Inc | Immunoglobulin variants and uses thereof |
| EP1613350B1 (en) | 2003-04-09 | 2009-03-18 | Genentech, Inc. | Therapy of autoimmune disease in a patient with an inadequate response to a tnf-alpha inhibitor |
| CN1802388B (zh) | 2003-05-09 | 2011-01-05 | 杜克大学 | Cd20特异抗体及使用它们的方法 |
| US8088387B2 (en) | 2003-10-10 | 2012-01-03 | Immunogen Inc. | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
| JP2007526220A (ja) | 2003-06-05 | 2007-09-13 | ジェネンテック・インコーポレーテッド | B細胞疾患の併用療法 |
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| US9296820B2 (en) | 2003-11-05 | 2016-03-29 | Roche Glycart Ag | Polynucleotides encoding anti-CD20 antigen binding molecules with increased Fc receptor binding affinity and effector function |
| KR20060107555A (ko) * | 2003-12-19 | 2006-10-13 | 제넨테크, 인크. | 이식 거부에서 cd20의 검출 |
| US7850962B2 (en) | 2004-04-20 | 2010-12-14 | Genmab A/S | Human monoclonal antibodies against CD20 |
| AU2005249566B2 (en) | 2004-06-04 | 2010-11-11 | Genentech, Inc. | Method for treating multiple sclerosis |
| AU2005274905B2 (en) | 2004-08-04 | 2010-12-23 | Mentrik Biotech, Llc | Variant Fc regions |
| JO3000B1 (ar) | 2004-10-20 | 2016-09-05 | Genentech Inc | مركبات أجسام مضادة . |
| ZA200709956B (en) | 2005-05-20 | 2009-02-25 | Genentech Inc | Pretreatment of a biological sample from an autoimmune disease subject |
| RU2421242C2 (ru) | 2005-07-25 | 2011-06-20 | Трабьон Фармасьютикалз, Инк. | Применение однократной дозы cd20-специфических связывающих молекул |
| RU2423381C2 (ru) | 2005-07-25 | 2011-07-10 | Трабьон Фармасьютикалз, Инк. | Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| ES2618543T3 (es) | 2005-11-23 | 2017-06-21 | Genentech, Inc. | Métodos y composiciones relacionados con ensayos de linfocitos B |
| NZ573646A (en) | 2006-06-12 | 2012-04-27 | Wyeth Llc | Single-chain multivalent binding proteins with effector function |
| KR102055873B1 (ko) | 2007-07-09 | 2019-12-13 | 제넨테크, 인크. | 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지 |
| CN101113459A (zh) * | 2007-07-16 | 2008-01-30 | 东莞太力生物工程有限公司 | 一种重组复制缺陷型病毒、含有该病毒的药物组合物及其应用 |
| HUE030134T2 (en) | 2007-10-16 | 2017-04-28 | Zymogenetics Inc | Combination of transmembrane activator and calcium modulator and cyclophilin ligand interactor (TACI) and anti-CD20 agents for the treatment of autoimmune diseases |
| US7914785B2 (en) | 2008-01-02 | 2011-03-29 | Bergen Teknologieverforing As | B-cell depleting agents, like anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| EP2077281A1 (en) | 2008-01-02 | 2009-07-08 | Bergen Teknologioverforing AS | Anti-CD20 antibodies or fragments thereof for the treatment of chronic fatigue syndrome |
| RU2531754C2 (ru) | 2008-04-11 | 2014-10-27 | ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US | Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством |
| AR073295A1 (es) | 2008-09-16 | 2010-10-28 | Genentech Inc | Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion. |
| WO2010075249A2 (en) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | A method for treating rheumatoid arthritis with b-cell antagonists |
| HRP20200768T4 (hr) | 2009-08-11 | 2025-03-28 | F. Hoffmann - La Roche Ag | Proizvodnja proteina u mediju za uzgoj stanica bez glutamina |
| DK3305813T3 (da) * | 2009-11-11 | 2020-04-20 | Astellas Pharma Inc | Antistoffer, der er specifikke for claudin 6 (cldn6) |
| KR20130009760A (ko) | 2010-02-10 | 2013-01-23 | 이뮤노젠 아이엔씨 | Cd20 항체 및 이의 용도 |
| EP3134113A4 (en) * | 2014-04-25 | 2017-11-29 | University of Florida Research Foundation, Inc. | Methods of permitting a subject to receive multiple doses of recombinant adeno-associated virus |
| EP3303373B1 (en) | 2015-05-30 | 2020-04-08 | Molecular Templates, Inc. | De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same |
| HUE057952T2 (hu) | 2015-06-24 | 2022-06-28 | Hoffmann La Roche | Anti-transzferrin receptor antitestek testreszabott affinitással |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| TWI873952B (zh) | 2015-10-02 | 2025-02-21 | 瑞士商赫孚孟拉羅股份公司 | 雙特異性抗‐人類cd20/人類轉鐵蛋白受體抗體及使用方法 |
| AR106189A1 (es) | 2015-10-02 | 2017-12-20 | Hoffmann La Roche | ANTICUERPOS BIESPECÍFICOS CONTRA EL A-b HUMANO Y EL RECEPTOR DE TRANSFERRINA HUMANO Y MÉTODOS DE USO |
| IL313608A (en) * | 2015-12-09 | 2024-08-01 | Hoffmann La Roche | Antibody against CD20 type II to reduce the formation of antibodies against drugs |
| TW202337494A (zh) | 2021-11-16 | 2023-10-01 | 美商建南德克公司 | 用莫蘇妥珠單抗治療全身性紅斑狼瘡(sle)之方法及組成物 |
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-
2000
- 2000-07-10 KR KR1020027000481A patent/KR20020027490A/ko not_active Ceased
- 2000-07-10 CA CA002379274A patent/CA2379274A1/en not_active Abandoned
- 2000-07-10 CN CNA200710169320XA patent/CN101264324A/zh active Pending
- 2000-07-10 JP JP2001509208A patent/JP2003528805A/ja not_active Withdrawn
- 2000-07-10 IL IL14754700A patent/IL147547A0/xx unknown
- 2000-07-10 MX MXPA02000419A patent/MXPA02000419A/es not_active Application Discontinuation
- 2000-07-10 AU AU60825/00A patent/AU778863B2/en not_active Ceased
- 2000-07-10 EP EP00947170A patent/EP1216056A1/en not_active Withdrawn
- 2000-07-10 KR KR1020087018967A patent/KR20080075044A/ko not_active Ceased
- 2000-07-10 NZ NZ516491A patent/NZ516491A/en unknown
- 2000-07-10 CN CN00812608A patent/CN1373672A/zh active Pending
- 2000-07-10 WO PCT/US2000/018776 patent/WO2001003734A1/en not_active Ceased
- 2000-07-10 HK HK02109138.2A patent/HK1047702A1/zh unknown
- 2000-07-10 HU HU0202238A patent/HUP0202238A3/hu unknown
- 2000-07-10 PL PL352758A patent/PL201086B1/pl not_active IP Right Cessation
- 2000-07-10 BR BR0013201-2A patent/BR0013201A/pt not_active Application Discontinuation
-
2002
- 2002-01-11 NO NO20020128A patent/NO20020128L/no not_active Application Discontinuation
- 2002-01-11 ZA ZA200200272A patent/ZA200200272B/xx unknown
-
2005
- 2005-03-18 AU AU2005201189A patent/AU2005201189B2/en not_active Ceased
-
2009
- 2009-09-08 US US12/555,177 patent/US20100003252A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU6082500A (en) | 2001-01-30 |
| CN1373672A (zh) | 2002-10-09 |
| NO20020128D0 (no) | 2002-01-11 |
| EP1216056A1 (en) | 2002-06-26 |
| NZ516491A (en) | 2004-11-26 |
| US20100003252A1 (en) | 2010-01-07 |
| AU2005201189B2 (en) | 2008-04-03 |
| HUP0202238A2 (en) | 2002-10-28 |
| IL147547A0 (en) | 2002-08-14 |
| PL201086B1 (pl) | 2009-03-31 |
| JP2003528805A (ja) | 2003-09-30 |
| MXPA02000419A (es) | 2004-09-10 |
| CN101264324A (zh) | 2008-09-17 |
| BR0013201A (pt) | 2002-04-30 |
| NO20020128L (no) | 2002-02-28 |
| HUP0202238A3 (en) | 2004-05-28 |
| CA2379274A1 (en) | 2001-01-18 |
| WO2001003734A1 (en) | 2001-01-18 |
| AU778863B2 (en) | 2004-12-23 |
| KR20080075044A (ko) | 2008-08-13 |
| HK1047702A1 (zh) | 2003-03-07 |
| AU2005201189A1 (en) | 2005-04-14 |
| KR20020027490A (ko) | 2002-04-13 |
| ZA200200272B (en) | 2003-03-26 |
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| LAPS | Decisions on the lapse of the protection rights |
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