PL354044A1 - Bicykliczni agoniści wazopresynyBicykliczni agoniści wazopresyny - Google Patents

Bicykliczni agoniści wazopresynyBicykliczni agoniści wazopresyny

Info

Publication number
PL354044A1
PL354044A1 PL00354044A PL35404400A PL354044A1 PL 354044 A1 PL354044 A1 PL 354044A1 PL 00354044 A PL00354044 A PL 00354044A PL 35404400 A PL35404400 A PL 35404400A PL 354044 A1 PL354044 A1 PL 354044A1
Authority
PL
Poland
Prior art keywords
alkyl
bicyclic
vasopressin agonists
agonists
independently
Prior art date
Application number
PL00354044A
Other languages
English (en)
Other versions
PL206211B1 (pl
Inventor
Doreen M.Ashworth Doreen M. Ashworth
Gary R.W.Pitt Gary R.W. Pitt
PeterHudson Peter Hudson
Christopher M.Yea Christopher M. Yea
Richard J.Franklin Richard J. Franklin
Original Assignee
Ferring Bvferring Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ferring Bvferring Bv filed Critical Ferring Bvferring Bv
Publication of PL354044A1 publication Critical patent/PL354044A1/pl
Publication of PL206211B1 publication Critical patent/PL206211B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D223/00Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16Benzazepines; Hydrogenated benzazepines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/12Antidiuretics, e.g. drugs for diabetes insipidus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D267/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/02Seven-membered rings
    • C07D267/08Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D267/12Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D267/14Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL354044A 1999-10-20 2000-10-20 N-acylowe pochodne tetrahydroazepiny, kompozycja farmaceutyczna i zastosowanie tych pochodnych PL206211B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9924836A GB2355454A (en) 1999-10-20 1999-10-20 Antidiuretic agents
PCT/GB2000/004055 WO2001029005A1 (en) 1999-10-20 2000-10-20 Bicyclic vasopressin agonists

Publications (2)

Publication Number Publication Date
PL354044A1 true PL354044A1 (pl) 2003-12-15
PL206211B1 PL206211B1 (pl) 2010-07-30

Family

ID=10863070

Family Applications (1)

Application Number Title Priority Date Filing Date
PL354044A PL206211B1 (pl) 1999-10-20 2000-10-20 N-acylowe pochodne tetrahydroazepiny, kompozycja farmaceutyczna i zastosowanie tych pochodnych

Country Status (22)

Country Link
US (1) US6664249B1 (pl)
EP (1) EP1226122B1 (pl)
JP (1) JP4694747B2 (pl)
KR (1) KR100725555B1 (pl)
CN (1) CN1144788C (pl)
AT (1) ATE284871T1 (pl)
AU (1) AU777092B2 (pl)
CA (1) CA2387886A1 (pl)
CZ (1) CZ304069B6 (pl)
DE (1) DE60016786T2 (pl)
ES (1) ES2234684T3 (pl)
GB (1) GB2355454A (pl)
HK (1) HK1044155B (pl)
HU (1) HU229357B1 (pl)
IL (2) IL148548A0 (pl)
MX (1) MXPA02003779A (pl)
NO (1) NO322920B1 (pl)
NZ (1) NZ517611A (pl)
PL (1) PL206211B1 (pl)
PT (1) PT1226122E (pl)
RU (1) RU2254332C2 (pl)
WO (1) WO2001029005A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0000079D0 (en) 2000-01-05 2000-02-23 Ferring Bv Novel antidiuretic agents
GB0015601D0 (en) 2000-06-26 2000-08-16 Ferring Bv Novel antidiuretic agents
GB0210397D0 (en) 2002-05-07 2002-06-12 Ferring Bv Pharmaceutical formulations
EP1530967B1 (en) * 2003-11-13 2006-05-03 Ferring B.V. Blister pack and solid dosage form comprising desmopressin
EP1632494A1 (en) 2004-08-24 2006-03-08 Ferring B.V. Vasopressin v1a antagonists
EP2392571A3 (en) * 2005-07-29 2012-03-14 F. Hoffmann-La Roche AG Indol-3-yl-carbonyl-piperidin and piperazin derivatives
SE528446C2 (sv) * 2006-03-02 2006-11-14 Ferring Int Ct Sa Farmaceutisk sammansättning innefattande desmopressin, kiseldioxid och stärkelse
RU2342949C1 (ru) * 2007-03-26 2009-01-10 Юрий Георгиевич Жуковский Применение [дезамино-1, изолейцин-3, аргинин-8]вазопрессина в качестве средства для увеличения выведения почкой солей натрия и усиления обратного избирательного всасывания из почечных канальцев в кровь воды-растворителя
AU2008283929B2 (en) 2007-08-06 2013-10-10 Serenity Pharmaceuticals, Llc Methods and devices for desmopressin drug delivery
US11963995B2 (en) 2008-05-21 2024-04-23 Ferring B.V. Methods comprising desmopressin
US20100286045A1 (en) 2008-05-21 2010-11-11 Bjarke Mirner Klein Methods comprising desmopressin
PL2712622T3 (pl) 2008-05-21 2017-01-31 Ferring B.V. Ulegająca rozpadowi w ustach desmopresyna do zwiększania początkowego okresu snu niezakłócanego przez nokturię
CN102942558B (zh) * 2012-05-18 2014-04-16 天津药物研究院 一种苯并氮杂卓衍生物的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2905909B2 (ja) * 1991-04-19 1999-06-14 大塚製薬株式会社 バソプレシン拮抗剤
US5753677A (en) * 1989-10-20 1998-05-19 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds
DK0450097T3 (da) 1989-10-20 1996-05-20 Otsuka Pharma Co Ltd Benzoheterocykliske forbindelser
TW198715B (pl) * 1991-04-19 1993-01-21 Dtsuka Seiyaku Kk
JPH05320135A (ja) * 1992-05-19 1993-12-03 Yamanouchi Pharmaceut Co Ltd テトラヒドロベンズアゼピン誘導体
AU657431B2 (en) 1992-08-20 1995-03-09 Otsuka Pharmaceutical Co., Ltd. Benzoheterocyclic compounds as oxytocin and vasopressin antagonists
JP2913082B2 (ja) * 1992-10-16 1999-06-28 大塚製薬株式会社 バソプレシン拮抗剤及びオキシトシン拮抗剤
TW270927B (pl) 1992-10-16 1996-02-21 Otsuka Pharma Co Ltd
WO1994012476A1 (fr) 1992-11-25 1994-06-09 Yamanouchi Pharmaceutical Co., Ltd. Derive de benzanilide
WO1994020473A1 (fr) * 1993-03-11 1994-09-15 Yamanouchi Pharmaceutical Co., Ltd. Compose avec action antagoniste de la vasopressine
RU2137760C1 (ru) * 1993-08-26 1999-09-20 Яманоути Фармасьютикал Ко., Лтд. Производное бензазепина, фармацевтическая композиция, производное дифторбензазепина и производное (замещенного) аминобензоилдифторбензазепина
JP2926335B2 (ja) * 1997-06-13 1999-07-28 大塚製薬株式会社 医薬組成物

Also Published As

Publication number Publication date
NO20021879D0 (no) 2002-04-19
CN1382125A (zh) 2002-11-27
HUP0203622A2 (hu) 2003-02-28
WO2001029005A1 (en) 2001-04-26
EP1226122A1 (en) 2002-07-31
JP4694747B2 (ja) 2011-06-08
HUP0203622A3 (en) 2005-01-28
KR20020029794A (ko) 2002-04-19
NO322920B1 (no) 2006-12-18
IL148548A0 (en) 2002-09-12
GB9924836D0 (en) 1999-12-22
AU1037401A (en) 2001-04-30
US6664249B1 (en) 2003-12-16
CZ304069B6 (cs) 2013-09-18
IL148548A (en) 2007-02-11
HK1044155A1 (en) 2002-10-11
PT1226122E (pt) 2005-04-29
DE60016786D1 (de) 2005-01-20
HK1044155B (en) 2005-05-06
DE60016786T2 (de) 2005-12-22
ATE284871T1 (de) 2005-01-15
KR100725555B1 (ko) 2007-06-08
RU2254332C2 (ru) 2005-06-20
GB2355454A (en) 2001-04-25
NZ517611A (en) 2002-11-26
ES2234684T3 (es) 2005-07-01
CA2387886A1 (en) 2001-04-26
HU229357B1 (en) 2013-11-28
JP2003512356A (ja) 2003-04-02
CN1144788C (zh) 2004-04-07
MXPA02003779A (es) 2002-09-30
CZ20021339A3 (cs) 2002-09-11
EP1226122B1 (en) 2004-12-15
PL206211B1 (pl) 2010-07-30
NO20021879L (no) 2002-04-19
AU777092B2 (en) 2004-09-30

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