PL355484A1 - Związek przeciwzakrzepowy - Google Patents

Związek przeciwzakrzepowy

Info

Publication number
PL355484A1
PL355484A1 PL00355484A PL35548400A PL355484A1 PL 355484 A1 PL355484 A1 PL 355484A1 PL 00355484 A PL00355484 A PL 00355484A PL 35548400 A PL35548400 A PL 35548400A PL 355484 A1 PL355484 A1 PL 355484A1
Authority
PL
Poland
Prior art keywords
antithrombotic compound
antithrombotic
compound
Prior art date
Application number
PL00355484A
Other languages
English (en)
Other versions
PL202840B1 (pl
Inventor
Boeckel Constant Adriaan Anton Van
Cornelia Maria Tromp
Tamara Theodora Maria Geertsen
Original Assignee
Akzo Nobel N.V.
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel N.V., Sanofi-Synthelabo filed Critical Akzo Nobel N.V.
Publication of PL355484A1 publication Critical patent/PL355484A1/pl
Publication of PL202840B1 publication Critical patent/PL202840B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL355484A 1999-12-07 2000-12-01 Związki o aktywności przeciwzakrzepowej, sposób wytwarzania tych związków, kompozycja farmaceutyczna i zastosowanie tych związków PL202840B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99204172 1999-12-07
PCT/EP2000/012155 WO2001042262A2 (en) 1999-12-07 2000-12-01 Antithrombotic compound

Publications (2)

Publication Number Publication Date
PL355484A1 true PL355484A1 (pl) 2004-05-04
PL202840B1 PL202840B1 (pl) 2009-07-31

Family

ID=8240976

Family Applications (1)

Application Number Title Priority Date Filing Date
PL355484A PL202840B1 (pl) 1999-12-07 2000-12-01 Związki o aktywności przeciwzakrzepowej, sposób wytwarzania tych związków, kompozycja farmaceutyczna i zastosowanie tych związków

Country Status (23)

Country Link
US (1) US6875755B2 (pl)
EP (1) EP1237897B1 (pl)
JP (1) JP4820517B2 (pl)
KR (1) KR100776607B1 (pl)
CN (1) CN1195767C (pl)
AR (1) AR026726A1 (pl)
AU (1) AU781846B2 (pl)
BR (1) BR0016217A (pl)
CA (1) CA2393042C (pl)
CO (1) CO5251449A1 (pl)
CZ (1) CZ303385B6 (pl)
HK (1) HK1047593A1 (pl)
HU (1) HUP0203471A3 (pl)
IL (2) IL149628A0 (pl)
NO (1) NO323059B1 (pl)
NZ (1) NZ519100A (pl)
PE (1) PE20010935A1 (pl)
PL (1) PL202840B1 (pl)
RU (1) RU2266913C2 (pl)
SK (1) SK287682B6 (pl)
TW (1) TWI289566B (pl)
WO (1) WO2001042262A2 (pl)
ZA (1) ZA200203799B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1440077B1 (en) * 2001-09-07 2013-05-01 Alchemia Limited Synthetic heparin pentasaccharides
US7208498B2 (en) 2002-07-15 2007-04-24 Merck & Co., Inc. Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes
ATE370141T1 (de) 2002-10-07 2007-09-15 Merck & Co Inc Antidiabetische heterocyclische beta- aminoverbindungen als inhibitoren von dipeptidylpeptidase
CA2504735C (en) * 2002-11-07 2009-06-23 Merck & Co., Inc. Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
EP1589969A4 (en) 2003-01-17 2008-08-13 Merck & Co Inc 3-AMINO-4-PHENYLBUTANEAN DERIVATEALS DIPEPTIDYLPEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES
CA2513684A1 (en) 2003-01-31 2004-08-19 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
US7560455B2 (en) 2003-05-14 2009-07-14 Merck & Co., Inc. 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
CN1798556A (zh) 2003-06-06 2006-07-05 麦克公司 作为治疗或者预防糖尿病的二肽基肽酶抑制剂的稠合吲哚
CN1809544A (zh) 2003-06-17 2006-07-26 麦克公司 作为二肽基肽酶抑制剂用于治疗或预防糖尿病的环己基甘氨酸衍生物
US7259160B2 (en) 2003-07-31 2007-08-21 Merck & Co., Inc. Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
EP1574516A1 (en) 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
TW200621794A (en) * 2004-10-06 2006-07-01 Akzo Nobel Nv Pulmonary administration of an antithrombotic compound
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
MY145269A (en) * 2005-10-10 2012-01-13 Organon Nv Antithrombotic dual inhibitors comprising a biotin label
JP6109574B2 (ja) 2009-12-18 2017-04-05 カタラン、フランス、バインハイム、ソシエテ、アノニムＣａｔａｌｅｎｔ Ｆｒａｎｃｅ Ｂｅｉｎｈｅｉｍ Ｓａ 合成オリゴサッカリドを含有する医薬経口剤形

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
DE4206858A1 (de) * 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
NZ264340A (en) * 1993-09-01 1995-04-27 Akzo Nobel Nv Bisconjugate comprising two saccharides and a spacer, use in pharmaceutical compositions
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
WO1999065934A1 (en) * 1998-06-17 1999-12-23 Akzo Nobel N.V. Antithrombotic compounds

Also Published As

Publication number Publication date
US20030114361A1 (en) 2003-06-19
WO2001042262A2 (en) 2001-06-14
RU2266913C2 (ru) 2005-12-27
NO20022689D0 (no) 2002-06-06
CA2393042A1 (en) 2001-06-14
SK7942002A3 (en) 2002-09-10
IL149628A0 (en) 2002-11-10
AU2003801A (en) 2001-06-18
JP2003520208A (ja) 2003-07-02
KR100776607B1 (ko) 2007-11-16
US6875755B2 (en) 2005-04-05
SK287682B6 (sk) 2011-06-06
TWI289566B (en) 2007-11-11
HUP0203471A2 (hu) 2003-02-28
HUP0203471A3 (en) 2003-03-28
NZ519100A (en) 2004-09-24
EP1237897B1 (en) 2015-01-14
ZA200203799B (en) 2003-10-29
IL149628A (en) 2010-04-29
EP1237897A2 (en) 2002-09-11
JP4820517B2 (ja) 2011-11-24
CA2393042C (en) 2011-06-28
CO5251449A1 (es) 2003-02-28
CZ303385B6 (cs) 2012-08-29
PL202840B1 (pl) 2009-07-31
KR20020070988A (ko) 2002-09-11
NO323059B1 (no) 2006-12-27
PE20010935A1 (es) 2001-09-20
NO20022689L (no) 2002-06-06
HK1047593A1 (zh) 2003-02-28
CN1407989A (zh) 2003-04-02
CZ20021958A3 (cs) 2002-08-14
WO2001042262A3 (en) 2001-12-13
CN1195767C (zh) 2005-04-06
AR026726A1 (es) 2003-02-26
AU781846B2 (en) 2005-06-16
BR0016217A (pt) 2002-09-10

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Legal Events

Date Code Title Description
LAPS Decisions on the lapse of the protection rights

Effective date: 20131201