PL3555074T3 - Aminopirazole jako selektywne inhibitory kinaz janusowych - Google Patents
Aminopirazole jako selektywne inhibitory kinaz janusowychInfo
- Publication number
- PL3555074T3 PL3555074T3 PL17821530.7T PL17821530T PL3555074T3 PL 3555074 T3 PL3555074 T3 PL 3555074T3 PL 17821530 T PL17821530 T PL 17821530T PL 3555074 T3 PL3555074 T3 PL 3555074T3
- Authority
- PL
- Poland
- Prior art keywords
- aminopyrazoles
- selective inhibitors
- janus kinases
- janus
- kinases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662434154P | 2016-12-14 | 2016-12-14 | |
| PCT/EP2017/082529 WO2018108969A1 (en) | 2016-12-14 | 2017-12-13 | Aminopyrazoles as selective janus kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3555074T3 true PL3555074T3 (pl) | 2022-11-07 |
Family
ID=60812050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17821530.7T PL3555074T3 (pl) | 2016-12-14 | 2017-12-13 | Aminopirazole jako selektywne inhibitory kinaz janusowych |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US10875847B2 (pl) |
| EP (2) | EP4095135A1 (pl) |
| JP (1) | JP7116063B2 (pl) |
| CN (2) | CN117756789A (pl) |
| AU (1) | AU2017376398B2 (pl) |
| CA (1) | CA3045951A1 (pl) |
| DK (1) | DK3555074T3 (pl) |
| ES (1) | ES2926545T3 (pl) |
| FI (1) | FIC20253009I1 (pl) |
| FR (1) | FR25C1047I1 (pl) |
| NL (1) | NL301349I2 (pl) |
| PL (1) | PL3555074T3 (pl) |
| RU (1) | RU2757218C2 (pl) |
| WO (1) | WO2018108969A1 (pl) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7497357B2 (ja) * | 2018-12-13 | 2024-06-10 | インターベット インターナショナル ベー． フェー． | １－［（３ｒ，４ｓ）－４－シアノテトラヒドロピラン－３－イル］－３－［（２－フルオロ－６－メトキシ－４－ピリジル）アミノ］ピラゾール－４－カルボキサミドの調製方法 |
| CN113195476A (zh) * | 2018-12-13 | 2021-07-30 | 英特维特国际股份有限公司 | 1-[(3r,4s)-4-氰基四氢吡喃-3-基]-3-[(2-氟-6-甲氧基-4-吡啶基)氨基]吡唑-4-甲酰胺的结晶形式 |
| WO2020118597A1 (en) * | 2018-12-13 | 2020-06-18 | Intervet International B.V. | Process for making 1- [ (3r, 4s) -4-cyanotetrahydropyran-3-yl] -3- [ (2-fluoro-6-methoxy-4-pyridyl) amino] pyrazole-4-carboxamide |
| KR102899382B1 (ko) | 2019-05-02 | 2025-12-12 | 인터벳 인터내셔널 비.브이. | 라세미 혼합물의 키랄 분리를 통한 에틸 3-아미노-1-[(3r,4s)-4-시아노테트라히드로피란-3-일]피라졸-4-카르복실레이트의 제조 방법 |
| KR20220119024A (ko) * | 2019-12-20 | 2022-08-26 | 인터벳 인터내셔널 비.브이. | 피라졸 제약 조성물 |
| MX2022007580A (es) * | 2019-12-20 | 2022-07-19 | Intervet Int Bv | Una composicion farmaceutica de un compuesto de pirazol dispersado en una matriz polimerica. |
| MX2022007676A (es) | 2019-12-20 | 2022-07-19 | Intervet Int Bv | Anticuerpos caninizados biespecificos para tratar dermatitis atopica. |
| JP2023545182A (ja) | 2020-10-15 | 2023-10-26 | インターベット インターナショナル ベー． フェー． | イヌインターロイキン－３１受容体アルファに対するイヌ化ラット抗体 |
| MX2023007150A (es) | 2020-12-18 | 2023-09-04 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de pirazol que contienen boro, composiciones que los comprenden, métodos y usos de los mismos. |
| JP2024532158A (ja) | 2021-08-20 | 2024-09-05 | インターベット インターナショナル ベー． フェー． | アトピー性皮膚炎を治療するためのホモ二量体融合タンパク質 |
| MX2024007090A (es) | 2021-12-16 | 2024-08-22 | Intervet Int Bv | Anticuerpos caninizados para el receptor alfa ii de interleucina-31 canino. |
| CN118541364A (zh) | 2021-12-24 | 2024-08-23 | 英特维特国际股份有限公司 | 氨基吡唑化合物的用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166452A (en) | 1976-05-03 | 1979-09-04 | Generales Constantine D J Jr | Apparatus for testing human responses to stimuli |
| US4256108A (en) | 1977-04-07 | 1981-03-17 | Alza Corporation | Microporous-semipermeable laminated osmotic system |
| US4265874A (en) | 1980-04-25 | 1981-05-05 | Alza Corporation | Method of delivering drug with aid of effervescent activity generated in environment of use |
| SK286640B6 (sk) | 1998-06-19 | 2009-03-05 | Pfizer Products Inc. | Pyrol [2,3-d] pyrimidínová zlúčenina, jej použitie na výrobu liečiva, farmaceutická kompozícia s jej obsahom, použitie jej kombinácie s ďalšími činidlami a súpravy s jej obsahom na výrobu liečiva |
| MX2008005814A (es) * | 2005-11-03 | 2008-10-15 | Vertex Pharma | Aminopirimidinas utiles como inhibidores de cinasa. |
| KR101335843B1 (ko) | 2008-08-20 | 2013-12-02 | 조에티스 엘엘씨 | 피롤로[2,3-ｄ]피리미딘 화합물 |
| CA2849168A1 (en) * | 2011-09-22 | 2013-03-28 | Merck Sharp & Dohme Corp. | Cycloalkylnitrile pyrazole carboxamides as janus kinase inhibitors |
| WO2014146246A1 (en) | 2013-03-19 | 2014-09-25 | Merck Sharp & Dohme Corp. | Cycloalkyl nitrile pyrazolo pyridones as janus kinase inhibitors |
| EP3286178A1 (en) * | 2015-04-21 | 2018-02-28 | Almirall S.A. | Amino-substituted heterocyclic derivatives as sodium channel inhibitors |
-
2017
- 2017-12-13 JP JP2019531369A patent/JP7116063B2/ja active Active
- 2017-12-13 CN CN202311769143.4A patent/CN117756789A/zh active Pending
- 2017-12-13 AU AU2017376398A patent/AU2017376398B2/en active Active
- 2017-12-13 CA CA3045951A patent/CA3045951A1/en active Pending
- 2017-12-13 DK DK17821530.7T patent/DK3555074T3/da active
- 2017-12-13 EP EP22178697.3A patent/EP4095135A1/en not_active Withdrawn
- 2017-12-13 CN CN201780077566.6A patent/CN110062754B/zh active Active
- 2017-12-13 ES ES17821530T patent/ES2926545T3/es active Active
- 2017-12-13 EP EP17821530.7A patent/EP3555074B1/en active Active
- 2017-12-13 RU RU2019121667A patent/RU2757218C2/ru active
- 2017-12-13 PL PL17821530.7T patent/PL3555074T3/pl unknown
- 2017-12-13 WO PCT/EP2017/082529 patent/WO2018108969A1/en not_active Ceased
- 2017-12-13 US US16/468,548 patent/US10875847B2/en active Active
-
2025
- 2025-11-21 NL NL301349C patent/NL301349I2/nl unknown
- 2025-11-25 FI FIC20253009C patent/FIC20253009I1/fi unknown
- 2025-11-28 FR FR25C1047C patent/FR25C1047I1/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2018108969A1 (en) | 2018-06-21 |
| EP3555074B1 (en) | 2022-07-27 |
| AU2017376398B2 (en) | 2021-07-15 |
| DK3555074T3 (da) | 2022-10-03 |
| FIC20253009I1 (fi) | 2025-11-25 |
| NL301349I2 (nl) | 2026-03-02 |
| FR25C1047I1 (fr) | 2026-01-02 |
| CN110062754A (zh) | 2019-07-26 |
| US20200115367A1 (en) | 2020-04-16 |
| AU2017376398A1 (en) | 2019-05-30 |
| ES2926545T3 (es) | 2022-10-26 |
| CA3045951A1 (en) | 2018-06-21 |
| RU2019121667A (ru) | 2021-01-15 |
| RU2757218C2 (ru) | 2021-10-12 |
| US10875847B2 (en) | 2020-12-29 |
| JP2020503288A (ja) | 2020-01-30 |
| JP7116063B2 (ja) | 2022-08-09 |
| RU2019121667A3 (pl) | 2021-02-25 |
| BR112019011835A2 (pt) | 2019-10-22 |
| EP4095135A1 (en) | 2022-11-30 |
| EP3555074A1 (en) | 2019-10-23 |
| CN110062754B (zh) | 2024-01-02 |
| CN117756789A (zh) | 2024-03-26 |
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