PL355811A1 - Nowe, rozgałęzione, podstawione aminopochodne 3-amino-1-fenylo-1H-[1,2,4] triazolu, sposób ich wytwarzania i zawierające je środki farmaceutyczne - Google Patents

Nowe, rozgałęzione, podstawione aminopochodne 3-amino-1-fenylo-1H-[1,2,4] triazolu, sposób ich wytwarzania i zawierające je środki farmaceutyczne

Info

Publication number
PL355811A1
PL355811A1 PL00355811A PL35581100A PL355811A1 PL 355811 A1 PL355811 A1 PL 355811A1 PL 00355811 A PL00355811 A PL 00355811A PL 35581100 A PL35581100 A PL 35581100A PL 355811 A1 PL355811 A1 PL 355811A1
Authority
PL
Poland
Prior art keywords
amino
phenyl
branched substituted
derivatives
novel branched
Prior art date
Application number
PL00355811A
Other languages
English (en)
Other versions
PL203819B1 (pl
Inventor
Michel Geslin
Danielle Gully
Jean-Pierre Maffrand
Pierre Roger
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of PL355811A1 publication Critical patent/PL355811A1/pl
Publication of PL203819B1 publication Critical patent/PL203819B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Rheumatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Pregnancy & Childbirth (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL355811A 1999-12-17 2000-12-14 Aminopochodne 3-amino-1-fenylo-1H-[1,2,4]triazolu, sposób ich wytwarzania, środek farmaceutyczny, zastosowanie tych związków i sposób wytwarzania związków pośrednich PL203819B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9915935A FR2802530B1 (fr) 1999-12-17 1999-12-17 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2,4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant
PCT/FR2000/003536 WO2001044207A2 (fr) 1999-12-17 2000-12-14 Nouveaux derives amino substitues ramifies du 3-amino-1-phenyl-1h[1,2 4]triazole, procedes pour leur preparation et compositions pharmaceutiques les contenant

Publications (2)

Publication Number Publication Date
PL355811A1 true PL355811A1 (pl) 2004-05-17
PL203819B1 PL203819B1 (pl) 2009-11-30

Family

ID=9553380

Family Applications (1)

Application Number Title Priority Date Filing Date
PL355811A PL203819B1 (pl) 1999-12-17 2000-12-14 Aminopochodne 3-amino-1-fenylo-1H-[1,2,4]triazolu, sposób ich wytwarzania, środek farmaceutyczny, zastosowanie tych związków i sposób wytwarzania związków pośrednich

Country Status (33)

Country Link
US (1) US6806282B2 (pl)
EP (1) EP1242389B1 (pl)
JP (1) JP4146641B2 (pl)
KR (1) KR100705525B1 (pl)
CN (1) CN1293061C (pl)
AR (1) AR031837A1 (pl)
AT (1) ATE264847T1 (pl)
AU (1) AU780711B2 (pl)
BR (1) BR0017023A (pl)
CA (1) CA2398772C (pl)
CO (1) CO5251379A1 (pl)
CZ (1) CZ302460B6 (pl)
DE (1) DE60010126T2 (pl)
DK (1) DK1242389T3 (pl)
EA (1) EA004957B1 (pl)
EE (1) EE04778B1 (pl)
ES (1) ES2219436T3 (pl)
FR (1) FR2802530B1 (pl)
HU (1) HUP0204080A3 (pl)
IL (2) IL150037A0 (pl)
IS (1) IS2315B (pl)
ME (1) MEP12108A (pl)
MX (1) MXPA02006033A (pl)
NO (1) NO20022828L (pl)
PL (1) PL203819B1 (pl)
PT (1) PT1242389E (pl)
RS (1) RS50289B (pl)
SK (1) SK285994B6 (pl)
TR (2) TR200201600T2 (pl)
TW (1) TWI289554B (pl)
UA (1) UA73333C2 (pl)
WO (1) WO2001044207A2 (pl)
ZA (1) ZA200204422B (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005013982A1 (en) * 2003-08-06 2005-02-17 Vertex Pharmaceuticals Incorporated Aminotriazole compounds useful as inhibitors of protein kinases
JO3019B1 (ar) 2006-04-19 2016-09-05 Janssen Pharmaceutica Nv ثلاثي مستبدل 4،2،1-ثلاثي زولات
CA2697974C (en) 2007-10-18 2015-06-30 Janssen Pharmaceutica Nv Trisubstituted 1,2,4-triazoles
JO2784B1 (en) 2007-10-18 2014-03-15 شركة جانسين فارماسوتيكا ان. في 5,3,1 - Triazole substitute derivative
WO2009115547A1 (en) 2008-03-19 2009-09-24 Janssen Pharmaceutica Nv Trisubstituted 1, 2, 4 -triazoiies as nicotinic acetylcholine receptor modulators
AR071763A1 (es) 2008-05-09 2010-07-14 Janssen Pharmaceutica Nv Pirazoles trisustituidos, composiciones farmaceuticas que los contienen, y usos de los mismos en el tratamiento de trastornos neurologicos y psiquiatricos
EP2629616A4 (en) * 2010-10-21 2014-03-26 Merck Sharp & Dohme SUBSTITUTED AMINO-TRIAZOLYL-PDE10-HEMMER
RS65839B1 (sr) 2014-01-21 2024-09-30 Neurocrine Biosciences Inc Crf1 receptor antagonisti za tretman kongenitalne adrenalne hiperplazije
CN104059027B (zh) * 2014-07-01 2015-10-28 河北大学 一类含1,2,4-三唑的(e)-甲氧基亚氨基苯乙酸甲酯类化合物及其制备方法和用途
US20220023266A1 (en) 2018-12-07 2022-01-27 Neurocrine Biosciences, Inc. Crf1 receptor antagonist, pharmaceutical formulations and solid forms thereof for the treatment of congenital adrenal hyperplasia
MX2022002881A (es) * 2019-09-25 2022-06-08 Oncoarendi Therapeutics Sa Proceso para la produccion de 5-(4-((2s,5s)-5-(4-clorobencil)-2-me tilmorfolino)piperidin-1-il)-1h-1,2,4-triazol-3-amina.
JP7623365B2 (ja) 2019-09-27 2025-01-28 ニューロクライン バイオサイエンシーズ，インコーポレイテッド Ｃｒｆ受容体アンタゴニストおよび使用方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3869167D1 (de) * 1987-03-27 1992-04-23 Kumiai Chemical Industry Co Phenyltriazol-derivate und insectizid.
US5795905A (en) * 1995-06-06 1998-08-18 Neurocrine Biosciences, Inc. CRF receptor antagonists and methods relating thereto
FR2763337B1 (fr) * 1997-05-13 1999-08-20 Sanofi Sa Nouveaux derives du triazole, un procede pour leur preparation et compositions pharmaceutiques les contenant

Also Published As

Publication number Publication date
TR200401775T4 (tr) 2004-09-21
CZ302460B6 (cs) 2011-06-01
EE04778B1 (et) 2007-02-15
JP4146641B2 (ja) 2008-09-10
PL203819B1 (pl) 2009-11-30
JP2003516975A (ja) 2003-05-20
US20030162771A1 (en) 2003-08-28
CN1434808A (zh) 2003-08-06
AU2525901A (en) 2001-06-25
HUP0204080A3 (en) 2005-01-28
PT1242389E (pt) 2004-08-31
EE200200331A (et) 2003-06-16
TWI289554B (en) 2007-11-11
BR0017023A (pt) 2002-12-03
CA2398772C (fr) 2011-07-05
KR100705525B1 (ko) 2007-04-10
KR20020061002A (ko) 2002-07-19
UA73333C2 (en) 2005-07-15
NO20022828L (no) 2002-08-19
AR031837A1 (es) 2003-10-08
FR2802530B1 (fr) 2002-02-22
ES2219436T3 (es) 2004-12-01
DE60010126T2 (de) 2005-04-28
WO2001044207B1 (fr) 2002-06-06
EA004957B1 (ru) 2004-10-28
EP1242389B1 (fr) 2004-04-21
MXPA02006033A (es) 2003-01-28
US6806282B2 (en) 2004-10-19
SK8502002A3 (en) 2003-02-04
IL150037A (en) 2007-02-11
IS2315B (is) 2007-11-15
SK285994B6 (sk) 2008-01-07
WO2001044207A8 (fr) 2001-07-12
HUP0204080A2 (hu) 2003-04-28
FR2802530A1 (fr) 2001-06-22
YU43902A (sh) 2005-03-15
MEP12108A (en) 2010-06-10
IS6402A (is) 2002-05-28
IL150037A0 (en) 2002-12-01
TR200201600T2 (tr) 2002-10-21
ATE264847T1 (de) 2004-05-15
DK1242389T3 (da) 2004-08-09
WO2001044207A3 (fr) 2001-12-20
AU780711B2 (en) 2005-04-14
NO20022828D0 (no) 2002-06-13
EP1242389A2 (fr) 2002-09-25
CA2398772A1 (fr) 2001-06-21
WO2001044207A2 (fr) 2001-06-21
DE60010126D1 (de) 2004-05-27
ZA200204422B (en) 2003-11-26
CN1293061C (zh) 2007-01-03
CO5251379A1 (es) 2003-02-28
HK1055947A1 (en) 2004-01-30
RS50289B (sr) 2009-09-08
EA200200523A1 (ru) 2002-12-26
CZ20022099A3 (cs) 2002-09-11

Similar Documents

Publication Publication Date Title
GB9907263D0 (en) Amino acid derivatives
PL339551A1 (en) Derivatives of rezorcin
PL350451A1 (en) Amide derivatives
PL337773A1 (en) Derivatives of benzimidazoles
EG23070A (en) Novel propargylether derivatives
IL148058A0 (en) Substituted 2-dialkylaminoalkylbiphenyl derivatives
PL352296A1 (en) Crystalline derivatives of 1-methylocarbapeneme
PL342817A1 (en) Novel derivatives of dihydroxyhexanic acid
PL340461A1 (en) Derivatives of isothiazocarboxylic acid
IL139884A0 (en) N-substituted derivatives of 5-oximinobarbituric acid
PL355811A1 (pl) Nowe, rozgałęzione, podstawione aminopochodne 3-amino-1-fenylo-1H-[1,2,4] triazolu, sposób ich wytwarzania i zawierające je środki farmaceutyczne
EG22530A (en) Preparation of substituted piperidin-4-ones
AU5919900A (en) Cyclized amino acid derivatives
PL351884A1 (en) Novel indole derivatives
PL334769A1 (en) Derivatives of 5-aroylnaphtene
IL150336A0 (en) Novel indole derivatives
HUP0102444A3 (en) Protein c derivatives
PL352409A1 (en) Derivatives of 1-trifluorometyl-4-hydroxy-7-piperidinyl-aminomethylochromane
HUP0204217A3 (en) Novel a-500359 derivatives
IL149534A0 (en) Preparation of 3-substituted-4-arylquinolin-2-one derivatives
EP1218407A4 (en) USES OF KAPPA-CONOTOXIN PVIIA
ZA985064B (en) Derivatives of pentaerythrits
HUP0201610A2 (en) Derivatives of 4'-demycarosyl-8a-aza-8a-homotylosin
PL325816A1 (en) Novel derivatives of naphtylpiperazine
HU9904011D0 (en) Novel salts of dipeptid derivatives

Legal Events

Date Code Title Description
RECP Rectifications of patent specification
RECP Rectifications of patent specification
LAPS Decisions on the lapse of the protection rights

Effective date: 20121214