PL3573617T3 - Związki na bazie pirazolu do stosowania w leczeniu nash i marskości wątroby - Google Patents

Związki na bazie pirazolu do stosowania w leczeniu nash i marskości wątroby

Info

Publication number
PL3573617T3
PL3573617T3 PL18871904.1T PL18871904T PL3573617T3 PL 3573617 T3 PL3573617 T3 PL 3573617T3 PL 18871904 T PL18871904 T PL 18871904T PL 3573617 T3 PL3573617 T3 PL 3573617T3
Authority
PL
Poland
Prior art keywords
pyrazol
cirrhosis
based compounds
treating nash
nash
Prior art date
Application number
PL18871904.1T
Other languages
English (en)
Inventor
Sung Hwan Moon
Soo Jin Lee
Sung Chan Lee
Yun Soo Bae
Original Assignee
Aptabio Therapeutics Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aptabio Therapeutics Inc. filed Critical Aptabio Therapeutics Inc.
Publication of PL3573617T3 publication Critical patent/PL3573617T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL18871904.1T 2017-11-01 2018-09-14 Związki na bazie pirazolu do stosowania w leczeniu nash i marskości wątroby PL3573617T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020170144911A KR101840702B1 (ko) 2017-11-01 2017-11-01 간질환 치료제
PCT/KR2018/010857 WO2019088444A1 (en) 2017-11-01 2018-09-14 Therapeutic agent for liver diseases

Publications (1)

Publication Number Publication Date
PL3573617T3 true PL3573617T3 (pl) 2024-07-15

Family

ID=61901100

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18871904.1T PL3573617T3 (pl) 2017-11-01 2018-09-14 Związki na bazie pirazolu do stosowania w leczeniu nash i marskości wątroby

Country Status (15)

Country Link
US (1) US10966969B2 (pl)
EP (1) EP3573617B1 (pl)
JP (1) JP6812564B2 (pl)
KR (1) KR101840702B1 (pl)
CN (1) CN110248659B (pl)
AU (1) AU2018358496B2 (pl)
BR (1) BR112019015715A2 (pl)
CA (1) CA3050865C (pl)
CL (1) CL2019002172A1 (pl)
CO (1) CO2019008053A2 (pl)
ES (1) ES2984413T3 (pl)
MX (1) MX386033B (pl)
PL (1) PL3573617T3 (pl)
RU (1) RU2723686C1 (pl)
WO (1) WO2019088444A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101840702B1 (ko) * 2017-11-01 2018-03-22 압타바이오 주식회사 간질환 치료제
KR102191180B1 (ko) * 2019-05-31 2020-12-15 삼진제약주식회사 안질환 치료용 조성물
AU2021253243B2 (en) * 2020-04-08 2024-01-18 Aptabio Therapeutics Inc. Agent for treating contrast-induced acute kidney injury
KR102386097B1 (ko) * 2020-04-13 2022-04-14 압타바이오 주식회사 피라졸 유도체의 폐섬유증 치료제
AU2021255160B2 (en) * 2020-04-13 2024-02-01 Aptabio Therapeutics Inc. Pulmonary fibrosis medicine containing pyrazole derivative
KR102481705B1 (ko) * 2020-08-04 2022-12-27 연세대학교 산학협력단 트리아졸 유도체를 유효성분으로 포함하는 간 섬유증의 예방 또는 치료용 조성물
IL303390A (en) 2020-12-03 2023-08-01 Battelle Memorial Institute Compositions of polymer nanoparticles and DNA nanostructures and methods for non-viral transport
KR102589130B1 (ko) * 2021-03-24 2023-10-13 삼진제약주식회사 N-옥소 피리딘 화합물 발생을 억제하는 안질환 예방 또는 치료용 점안 조성물
WO2022216977A1 (en) 2021-04-07 2022-10-13 Batelle Memorial Institute Rapid design, build, test, and learn technologies for identifying and using non-viral carriers
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
AU2024393766A1 (en) 2023-12-08 2026-06-18 Battelle Memorial Institute Use of dna origami nanostructures for molecular information based data storage systems
WO2026134549A1 (ko) * 2024-12-19 2026-06-25 서울대학교산학협력단 피라졸 유도체를 포함하는 혈전성 질환의 예방 또는 치료용 약학 조성물

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JP2007210978A (ja) 2006-02-13 2007-08-23 Hiroshima Univ 耐糖能障害、ｉｉ型糖尿病、高脂血症、メタボリックシンドローム、内臓脂肪型肥満、脂肪肝または非アルコール性脂肪性肝炎の予防・治療剤
US7994094B2 (en) * 2006-09-01 2011-08-09 Otsuka Agritechno Co., Ltd. N-pyridylpiperidine compound, method for producing the same, and pest control agent
KR100942382B1 (ko) * 2008-03-25 2010-02-12 이화여자대학교 산학협력단 피라졸 유도체를 포함하는 골다공증 예방 및 치료용 조성물
KR101280160B1 (ko) * 2009-09-02 2013-06-28 이화여자대학교 산학협력단 피라졸 유도체, 이의 제조방법 및 이를 포함하는 골다공증 예방 및 치료용 조성물
SMT201700581T1 (it) 2009-12-21 2018-01-11 Samumed Llc 1h-pirazolo[3,4-b]piridine e loro usi terapeutici
JP2013249256A (ja) 2010-09-15 2013-12-12 Astellas Pharma Inc 脂肪性肝疾患治療薬
KR20120098489A (ko) 2011-02-28 2012-09-05 이화여자대학교 산학협력단 피라졸 유도체를 포함하는 심혈관 질환 예방 및 치료용 조성물
KR20120098462A (ko) * 2011-02-28 2012-09-05 이화여자대학교 산학협력단 피라졸 유도체, 이의 제조방법 및 이를 포함하는 골다공증 예방 및 치료용 조성물
CN103459383B (zh) 2011-09-30 2016-06-22 财团法人国家卫生研究院 吡唑类化合物
KR101633957B1 (ko) * 2012-08-27 2016-06-27 이화여자대학교 산학협력단 피라졸 유도체를 포함하는 신장질환 예방 또는 치료용 조성물
US9695127B2 (en) 2012-11-08 2017-07-04 University of Pittsburgh—of the Commonwealth System of Higher Education Compounds for treating HIV and methods for using the compounds
CN104288149B (zh) 2014-10-22 2017-02-15 山东大学 4‑氯‑2‑(5‑苯基‑1‑(吡啶‑2‑基)‑4,5‑二氢‑1h‑吡唑‑3‑基)苯酚在制药中的应用
JP2019077615A (ja) 2016-03-09 2019-05-23 公立大学法人和歌山県立医科大学 非アルコール性脂肪性肝疾患／非アルコール性脂肪性肝炎の治療剤
KR101856444B1 (ko) * 2017-04-20 2018-05-10 압타바이오 주식회사 3-페닐-4-프로필-1-(피리딘-2-일)-1ｈ-피라졸-5-올 염산염의 신규 결정형 고체 화합물
KR101840702B1 (ko) * 2017-11-01 2018-03-22 압타바이오 주식회사 간질환 치료제

Also Published As

Publication number Publication date
JP6812564B2 (ja) 2021-01-13
AU2018358496B2 (en) 2020-12-10
CN110248659B (zh) 2022-08-19
RU2723686C1 (ru) 2020-06-17
EP3573617A4 (en) 2020-04-22
MX2019008870A (es) 2020-01-20
WO2019088444A1 (en) 2019-05-09
BR112019015715A2 (pt) 2020-03-24
ES2984413T3 (es) 2024-10-29
CA3050865A1 (en) 2019-05-09
AU2018358496A1 (en) 2019-08-08
CA3050865C (en) 2022-07-12
CL2019002172A1 (es) 2019-10-25
US20200390752A1 (en) 2020-12-17
MX386033B (es) 2025-03-18
EP3573617A1 (en) 2019-12-04
US10966969B2 (en) 2021-04-06
JP2020506917A (ja) 2020-03-05
CO2019008053A2 (es) 2019-10-21
CN110248659A (zh) 2019-09-17
EP3573617B1 (en) 2024-04-03
KR101840702B1 (ko) 2018-03-22

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