PL3573988T3 - Sposób wytwarzania pochodnych puryny - Google Patents

Sposób wytwarzania pochodnych puryny

Info

Publication number
PL3573988T3
PL3573988T3 PL18702530.9T PL18702530T PL3573988T3 PL 3573988 T3 PL3573988 T3 PL 3573988T3 PL 18702530 T PL18702530 T PL 18702530T PL 3573988 T3 PL3573988 T3 PL 3573988T3
Authority
PL
Poland
Prior art keywords
purine derivatives
preparing purine
preparing
derivatives
purine
Prior art date
Application number
PL18702530.9T
Other languages
English (en)
Inventor
Ben SKEAD
Robert Westwood
Derek Londesbrough
Julian Northen
Chris ATHERTON
Original Assignee
Cyclacel Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1701319.4A external-priority patent/GB201701319D0/en
Priority claimed from GBGB1701318.6A external-priority patent/GB201701318D0/en
Priority claimed from GBGB1701398.8A external-priority patent/GB201701398D0/en
Priority claimed from GBGB1701397.0A external-priority patent/GB201701397D0/en
Application filed by Cyclacel Limited filed Critical Cyclacel Limited
Publication of PL3573988T3 publication Critical patent/PL3573988T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL18702530.9T 2017-01-26 2018-01-25 Sposób wytwarzania pochodnych puryny PL3573988T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1701319.4A GB201701319D0 (en) 2017-01-26 2017-01-26 Process
GBGB1701318.6A GB201701318D0 (en) 2017-01-26 2017-01-26 Process
GBGB1701398.8A GB201701398D0 (en) 2017-01-27 2017-01-27 Process
GBGB1701397.0A GB201701397D0 (en) 2017-01-27 2017-01-27 Process
PCT/GB2018/050208 WO2018138500A1 (en) 2017-01-26 2018-01-25 Process for preparing purine derivatives

Publications (1)

Publication Number Publication Date
PL3573988T3 true PL3573988T3 (pl) 2023-05-08

Family

ID=61132821

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18702530.9T PL3573988T3 (pl) 2017-01-26 2018-01-25 Sposób wytwarzania pochodnych puryny

Country Status (10)

Country Link
US (1) US10927113B2 (pl)
EP (2) EP4212533A1 (pl)
JP (2) JP7122759B2 (pl)
KR (1) KR102524773B1 (pl)
CN (1) CN110248943B (pl)
AU (1) AU2018213119B2 (pl)
CA (1) CA3050061A1 (pl)
ES (1) ES2939049T3 (pl)
PL (1) PL3573988T3 (pl)
WO (1) WO2018138500A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102524773B1 (ko) * 2017-01-26 2023-04-21 싸이클라셀 리미티드 퓨린 유도체의 제조 방법
GB202000901D0 (en) 2020-01-22 2020-03-04 Cyclacel Ltd Process
WO2024105159A1 (en) * 2022-11-16 2024-05-23 University Of Zurich Ligands of the m6a-rna readers
WO2026024674A1 (en) 2024-07-22 2026-01-29 Genesis Therapeutics, Inc. Methods of treating skp2-associated cancers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1399446B1 (en) 2001-06-27 2005-08-03 Cyclacel Limited 2,6,9-substituted purine derivatives and their use in the treatment of proliferative disorders
GB0219054D0 (en) 2002-08-15 2002-09-25 Cyclacel Ltd New purine derivatives
TW200624435A (en) 2004-08-12 2006-07-16 Merck Patent Gmbh Process for preparing iridium(Ⅲ) ketoketonates
CA2576159A1 (en) 2004-08-27 2006-03-02 Cyclacel Limited Purine and pyrimidine cdk inhibitors and their use for the treatment of autoimmune diseases
CL2007002994A1 (es) * 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
JP5151167B2 (ja) 2007-01-31 2013-02-27 住友化学株式会社 Ｄｎａメチル化測定方法
GB0706632D0 (en) 2007-04-04 2007-05-16 Cyclacel Ltd New purine derivatives
EP2310015A4 (en) * 2008-07-14 2011-10-26 Cropsolution Inc ACETYL-COENZYME-CARBOXYLASE MODULATORS AND METHODS OF USE THEREOF
GB201001075D0 (en) * 2010-01-22 2010-03-10 Cyclacel Ltd Crystalline forms
JP5744021B2 (ja) 2010-06-30 2015-07-01 富士フイルム株式会社 新規なニコチンアミド誘導体またはその塩
KR102524773B1 (ko) 2017-01-26 2023-04-21 싸이클라셀 리미티드 퓨린 유도체의 제조 방법

Also Published As

Publication number Publication date
CN110248943A (zh) 2019-09-17
AU2018213119A1 (en) 2019-07-25
EP4212533A1 (en) 2023-07-19
JP7492765B2 (ja) 2024-05-30
EP3573988B1 (en) 2022-12-28
US20190389863A1 (en) 2019-12-26
JP2020505348A (ja) 2020-02-20
AU2018213119B2 (en) 2021-10-28
EP3573988A1 (en) 2019-12-04
ES2939049T3 (es) 2023-04-18
CN110248943B (zh) 2022-09-20
JP2022163113A (ja) 2022-10-25
KR20190111043A (ko) 2019-10-01
CA3050061A1 (en) 2018-08-02
KR102524773B1 (ko) 2023-04-21
WO2018138500A1 (en) 2018-08-02
US10927113B2 (en) 2021-02-23
JP7122759B2 (ja) 2022-08-22

Similar Documents

Publication Publication Date Title
IL274439A (en) Process for making Tapinaroff
IL292429B2 (en) An improved process for the preparation of aminopyrimidine derivatives
ZA201708142B (en) Process for preparing 4-amino-pyridazines
EP3325443A4 (en) PROCESS FOR THE PREPARATION OF PRIDOPIDINE
IL275216A (en) A process for the preparation of anthelmintic 4-aminoquinoline-3-carboxamide
PL3526229T3 (pl) Sposób wytwarzania glukopiranozylo-podstawionych pochodnych benzylo-benzenu
IL253381A0 (en) History of h9-pyrrolo-dipyridine
PL3364800T3 (pl) Sposób wytwarzania zasadniczo cylindrycznych artykułów
IL272114A (en) A process for the preparation of phosphorus-containing alpha-aminonitriles
IL253877B (en) Process for the preparation of 3-chloro-2-vinylphenylsulfonates
IL248565B (en) A process for the preparation of thiazole derivatives
PT3253743T (pt) Processo sintetico para preparar derivados do acido 2-furoico
ZA201801650B (en) Process for producing novel 4-benzoazonine derivatives
IL248568B (en) A process for the preparation of dihydroisoxazole derivatives
ZA201908452B (en) Improved process for preparing imetelstat
IL271512B (en) A method for the preparation of modified 4-aminoindan derivatives
IL273639A (en) A process for the preparation of pyrrolidine alpha-carboxamide derivatives
IL273695A (en) A process for preparing Spiro histories
ZA201807441B (en) Process for preparing oxathiazin-like compounds
IL253630B (en) A process for the preparation of modified phenylisoxazoline derivatives
HK40036649A (en) Process for preparing tapinarof
IL253830B (en) Process for the preparation of piperidine-4-carbothioamide hydrochloride
HUP1700275A2 (en) Process for self-host
GB201414880D0 (en) Process for making phosphate derivatives