PL3573988T3 - Sposób wytwarzania pochodnych puryny - Google Patents

Sposób wytwarzania pochodnych puryny

Info

Publication number
PL3573988T3
PL3573988T3 PL18702530.9T PL18702530T PL3573988T3 PL 3573988 T3 PL3573988 T3 PL 3573988T3 PL 18702530 T PL18702530 T PL 18702530T PL 3573988 T3 PL3573988 T3 PL 3573988T3
Authority
PL
Poland
Prior art keywords
purine derivatives
preparing purine
preparing
derivatives
purine
Prior art date
Application number
PL18702530.9T
Other languages
English (en)
Inventor
Ben SKEAD
Robert Westwood
Derek Londesbrough
Julian Northen
Chris ATHERTON
Original Assignee
Cyclacel Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1701319.4A external-priority patent/GB201701319D0/en
Priority claimed from GBGB1701318.6A external-priority patent/GB201701318D0/en
Priority claimed from GBGB1701397.0A external-priority patent/GB201701397D0/en
Priority claimed from GBGB1701398.8A external-priority patent/GB201701398D0/en
Application filed by Cyclacel Limited filed Critical Cyclacel Limited
Publication of PL3573988T3 publication Critical patent/PL3573988T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/02Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52Purines, e.g. adenine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D473/00Heterocyclic compounds containing purine ring systems
    • C07D473/40Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL18702530.9T 2017-01-26 2018-01-25 Sposób wytwarzania pochodnych puryny PL3573988T3 (pl)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB1701319.4A GB201701319D0 (en) 2017-01-26 2017-01-26 Process
GBGB1701318.6A GB201701318D0 (en) 2017-01-26 2017-01-26 Process
GBGB1701397.0A GB201701397D0 (en) 2017-01-27 2017-01-27 Process
GBGB1701398.8A GB201701398D0 (en) 2017-01-27 2017-01-27 Process
PCT/GB2018/050208 WO2018138500A1 (en) 2017-01-26 2018-01-25 Process for preparing purine derivatives

Publications (1)

Publication Number Publication Date
PL3573988T3 true PL3573988T3 (pl) 2023-05-08

Family

ID=61132821

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18702530.9T PL3573988T3 (pl) 2017-01-26 2018-01-25 Sposób wytwarzania pochodnych puryny

Country Status (10)

Country Link
US (1) US10927113B2 (pl)
EP (2) EP4212533A1 (pl)
JP (2) JP7122759B2 (pl)
KR (1) KR102524773B1 (pl)
CN (1) CN110248943B (pl)
AU (1) AU2018213119B2 (pl)
CA (1) CA3050061A1 (pl)
ES (1) ES2939049T3 (pl)
PL (1) PL3573988T3 (pl)
WO (1) WO2018138500A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102524773B1 (ko) * 2017-01-26 2023-04-21 싸이클라셀 리미티드 퓨린 유도체의 제조 방법
GB202000901D0 (en) * 2020-01-22 2020-03-04 Cyclacel Ltd Process
WO2024105159A1 (en) * 2022-11-16 2024-05-23 University Of Zurich Ligands of the m6a-rna readers
WO2026024674A1 (en) 2024-07-22 2026-01-29 Genesis Therapeutics, Inc. Methods of treating skp2-associated cancers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60205376T2 (de) 2001-06-27 2006-04-06 Cyclacel Ltd. 2,6,9-substituierte purinderivate und ihre verwendung bei der behandlung proliferativer krankheiten
GB0219054D0 (en) 2002-08-15 2002-09-25 Cyclacel Ltd New purine derivatives
TW200624435A (en) * 2004-08-12 2006-07-16 Merck Patent Gmbh Process for preparing iridium(Ⅲ) ketoketonates
US20080125404A1 (en) 2004-08-27 2008-05-29 Cyclacel Limited Purine and Pyrimidine Cdk Inhitbitors and Their use for The Treatment of Autoimmune Diseases
CL2007002994A1 (es) * 2006-10-19 2008-02-08 Wyeth Corp Compuestos derivados heterociclicos que contienen sulfamoilo, inhibidores de hsp90; composicion farmaceutica; y uso para el tratamiento del cancer, tal como cancer de mama, de colon y prostata, entre otros.
JP5151167B2 (ja) 2007-01-31 2013-02-27 住友化学株式会社 Dnaメチル化測定方法
GB0706632D0 (en) * 2007-04-04 2007-05-16 Cyclacel Ltd New purine derivatives
AU2009271634A1 (en) * 2008-07-14 2010-01-21 Cropsolution, Inc. Modulators of acetyl-coenzyme a carboxylase and methods of use thereof
GB201001075D0 (en) * 2010-01-22 2010-03-10 Cyclacel Ltd Crystalline forms
ES2689103T3 (es) 2010-06-30 2018-11-08 Fujifilm Corporation Nuevo derivado de nicotinamida o sal del mismo
KR102524773B1 (ko) 2017-01-26 2023-04-21 싸이클라셀 리미티드 퓨린 유도체의 제조 방법

Also Published As

Publication number Publication date
US20190389863A1 (en) 2019-12-26
CN110248943B (zh) 2022-09-20
WO2018138500A1 (en) 2018-08-02
JP2022163113A (ja) 2022-10-25
AU2018213119A1 (en) 2019-07-25
JP7492765B2 (ja) 2024-05-30
JP7122759B2 (ja) 2022-08-22
US10927113B2 (en) 2021-02-23
AU2018213119B2 (en) 2021-10-28
CN110248943A (zh) 2019-09-17
CA3050061A1 (en) 2018-08-02
KR102524773B1 (ko) 2023-04-21
EP3573988B1 (en) 2022-12-28
EP4212533A1 (en) 2023-07-19
ES2939049T3 (es) 2023-04-18
EP3573988A1 (en) 2019-12-04
JP2020505348A (ja) 2020-02-20
KR20190111043A (ko) 2019-10-01

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