PL357547A1 - Pochodne 8,8a-dihydro-indeno [1,2-d] tiazolu, podstawione w pozycji 8a, sposób ich wytwarzania orazich zastosowanie jako leku, na przykład jako anorektyków - Google Patents

Pochodne 8,8a-dihydro-indeno [1,2-d] tiazolu, podstawione w pozycji 8a, sposób ich wytwarzania orazich zastosowanie jako leku, na przykład jako anorektyków

Info

Publication number
PL357547A1
PL357547A1 PL01357547A PL35754701A PL357547A1 PL 357547 A1 PL357547 A1 PL 357547A1 PL 01357547 A PL01357547 A PL 01357547A PL 35754701 A PL35754701 A PL 35754701A PL 357547 A1 PL357547 A1 PL 357547A1
Authority
PL
Poland
Prior art keywords
indeno
medicaments
dihydro
substituted
production
Prior art date
Application number
PL01357547A
Other languages
English (en)
Inventor
Gerhard Jaehne
Matthias Gossel
Martin Bickel
Original Assignee
Aventis Pharma Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland Gmbh filed Critical Aventis Pharma Deutschland Gmbh
Publication of PL357547A1 publication Critical patent/PL357547A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Fuses (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Indole Compounds (AREA)
PL01357547A 2000-02-23 2001-02-12 Pochodne 8,8a-dihydro-indeno [1,2-d] tiazolu, podstawione w pozycji 8a, sposób ich wytwarzania orazich zastosowanie jako leku, na przykład jako anorektyków PL357547A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10008275 2000-02-23

Publications (1)

Publication Number Publication Date
PL357547A1 true PL357547A1 (pl) 2004-07-26

Family

ID=7631989

Family Applications (1)

Application Number Title Priority Date Filing Date
PL01357547A PL357547A1 (pl) 2000-02-23 2001-02-12 Pochodne 8,8a-dihydro-indeno [1,2-d] tiazolu, podstawione w pozycji 8a, sposób ich wytwarzania orazich zastosowanie jako leku, na przykład jako anorektyków

Country Status (26)

Country Link
US (1) US6403624B1 (pl)
EP (1) EP1259498B1 (pl)
JP (1) JP4898052B2 (pl)
KR (1) KR20020079891A (pl)
CN (1) CN1195747C (pl)
AT (1) ATE283265T1 (pl)
AU (1) AU781003B2 (pl)
BR (1) BR0108605A (pl)
CA (1) CA2400698A1 (pl)
CZ (1) CZ20022838A3 (pl)
DE (1) DE50104600D1 (pl)
EE (1) EE200200466A (pl)
ES (1) ES2231482T3 (pl)
HR (1) HRP20020688A2 (pl)
HU (1) HUP0300140A3 (pl)
IL (1) IL151327A0 (pl)
MX (1) MXPA02007021A (pl)
NO (1) NO20023978L (pl)
NZ (1) NZ520926A (pl)
PL (1) PL357547A1 (pl)
PT (1) PT1259498E (pl)
RU (1) RU2261860C2 (pl)
SK (1) SK12162002A3 (pl)
WO (1) WO2001062746A1 (pl)
YU (1) YU56302A (pl)
ZA (1) ZA200206487B (pl)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10142660A1 (de) * 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von Derivaten von C2-substituierten Indan-1-ol-Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
DE10142659A1 (de) 2001-08-31 2003-03-20 Aventis Pharma Gmbh Verwendung von mehrfach substituierten Indan-1-ol. Systemen zur Herstellung von Medikamenten zur Prophylaxe oder Behandlung von Obesitas
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
EP1734963A4 (en) 2004-04-02 2008-06-18 Merck & Co Inc METHOD FOR TREATING PEOPLE WITH METABOLIC AND ANTHROPOMETRIC DISORDER
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
MX354786B (es) 2007-06-04 2018-03-21 Synergy Pharmaceuticals Inc Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos.
ES2522968T3 (es) 2008-06-04 2014-11-19 Synergy Pharmaceuticals Inc. Agonistas de guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros trastornos
AU2009270833B2 (en) 2008-07-16 2015-02-19 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
EP2348857B1 (en) 2008-10-22 2016-02-24 Merck Sharp & Dohme Corp. Novel cyclic benzimidazole derivatives useful anti-diabetic agents
US8329914B2 (en) 2008-10-31 2012-12-11 Merck Sharp & Dohme Corp Cyclic benzimidazole derivatives useful as anti-diabetic agents
JP2013520502A (ja) 2010-02-25 2013-06-06 メルク・シャープ・エンド・ドーム・コーポレイション 有用な抗糖尿病薬である新規な環状ベンズイミダゾール誘導体
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
SG192941A1 (en) 2011-02-25 2013-09-30 Merck Sharp & Dohme Novel cyclic azabenzimidazole derivatives useful as anti-diabetic agents
DK2681236T3 (en) 2011-03-01 2018-04-16 Synergy Pharmaceuticals Inc PROCEDURE FOR MANUFACTURING GUANYLATE CYCLASE-C-AGONISTS
RU2015106909A (ru) 2012-08-02 2016-09-27 Мерк Шарп И Доум Корп. Антидиабетические трициклические соединения
KR20150118158A (ko) 2013-02-22 2015-10-21 머크 샤프 앤드 돔 코포레이션 항당뇨병 비시클릭 화합물
WO2014139388A1 (en) 2013-03-14 2014-09-18 Merck Sharp & Dohme Corp. Novel indole derivatives useful as anti-diabetic agents
AU2014235209B2 (en) 2013-03-15 2018-06-14 Bausch Health Ireland Limited Guanylate cyclase receptor agonists combined with other drugs
AU2014235215A1 (en) 2013-03-15 2015-10-01 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
BR112015030326A2 (pt) 2013-06-05 2017-08-29 Synergy Pharmaceuticals Inc Agonistas ultrapuros de guanilato ciclase c, método de fabricar e usar os mesmos
WO2015051496A1 (en) 2013-10-08 2015-04-16 Merck Sharp & Dohme Corp. Antidiabetic tricyclic compounds
US11072602B2 (en) 2016-12-06 2021-07-27 Merck Sharp & Dohme Corp. Antidiabetic heterocyclic compounds
EP3558298B1 (en) 2016-12-20 2026-03-11 Merck Sharp & Dohme LLC Antidiabetic spirochroman compounds

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3507868A (en) * 1968-10-21 1970-04-21 Sandoz Ag Imidazo(2,1-b)thiazoles and thiazolo(3,2-a)pyrimidines
DE2640358A1 (de) 1976-09-08 1978-03-16 Hoechst Ag Thiazolidinderivate und verfahren zu ihrer herstellung
CA1292226C (en) * 1986-01-16 1991-11-19 Terumi Hachiya Indenothiazole derivative and process for preparing the same
GB9517381D0 (en) * 1995-08-24 1995-10-25 Pharmacia Spa Aryl and heteroaryl piperazine derivatives
DE19844547C2 (de) * 1998-09-29 2002-11-07 Aventis Pharma Gmbh Polycyclische Dihydrothiazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
DE19908539A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Dihydrothiazolsysteme, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
KR20020079891A (ko) 2002-10-19
JP4898052B2 (ja) 2012-03-14
MXPA02007021A (es) 2003-03-27
HK1055117A1 (en) 2003-12-24
CZ20022838A3 (cs) 2002-11-13
NZ520926A (en) 2004-08-27
US20020058658A1 (en) 2002-05-16
AU781003B2 (en) 2005-04-28
BR0108605A (pt) 2002-11-19
IL151327A0 (en) 2003-04-10
EP1259498A1 (de) 2002-11-27
US6403624B1 (en) 2002-06-11
NO20023978D0 (no) 2002-08-21
ZA200206487B (en) 2003-10-16
WO2001062746A1 (de) 2001-08-30
RU2261860C2 (ru) 2005-10-10
EP1259498B1 (de) 2004-11-24
ES2231482T3 (es) 2005-05-16
HUP0300140A2 (en) 2003-05-28
AU5615301A (en) 2001-09-03
ATE283265T1 (de) 2004-12-15
JP2003528825A (ja) 2003-09-30
CA2400698A1 (en) 2001-08-30
EE200200466A (et) 2003-12-15
RU2002125460A (ru) 2004-01-10
NO20023978L (no) 2002-10-18
SK12162002A3 (sk) 2003-02-04
CN1195747C (zh) 2005-04-06
CN1423640A (zh) 2003-06-11
HRP20020688A2 (en) 2004-12-31
PT1259498E (pt) 2005-02-28
DE50104600D1 (de) 2004-12-30
HUP0300140A3 (en) 2004-10-28
YU56302A (sh) 2005-11-28

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