PL357780A1 - Pochodne hydroksyfenylopiperydyn-4-ylidenometylobenzamidu do leczenia bólu - Google Patents
Pochodne hydroksyfenylopiperydyn-4-ylidenometylobenzamidu do leczenia bóluInfo
- Publication number
- PL357780A1 PL357780A1 PL01357780A PL35778001A PL357780A1 PL 357780 A1 PL357780 A1 PL 357780A1 PL 01357780 A PL01357780 A PL 01357780A PL 35778001 A PL35778001 A PL 35778001A PL 357780 A1 PL357780 A1 PL 357780A1
- Authority
- PL
- Poland
- Prior art keywords
- treatement
- ylidene
- piperidin
- hydroxyphenyl
- pain
- Prior art date
Links
- VCTJCAQVWZSOSM-UHFFFAOYSA-N 4-hydroxy-2-methyl-3-phenyl-n-piperidin-4-ylidenebenzamide Chemical class CC1=C(C(=O)N=C2CCNCC2)C=CC(O)=C1C1=CC=CC=C1 VCTJCAQVWZSOSM-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0001207A SE0001207D0 (sv) | 2000-04-04 | 2000-04-04 | Novel compounds |
| PCT/SE2001/000707 WO2001074804A1 (en) | 2000-04-04 | 2001-03-30 | Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL357780A1 true PL357780A1 (pl) | 2004-07-26 |
Family
ID=20279146
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL01357780A PL357780A1 (pl) | 2000-04-04 | 2001-03-30 | Pochodne hydroksyfenylopiperydyn-4-ylidenometylobenzamidu do leczenia bólu |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US6756387B2 (pl) |
| EP (1) | EP1282616B1 (pl) |
| JP (1) | JP2003529596A (pl) |
| KR (1) | KR20020084285A (pl) |
| CN (1) | CN1185228C (pl) |
| AR (1) | AR027983A1 (pl) |
| AT (1) | ATE269324T1 (pl) |
| AU (1) | AU2001244981A1 (pl) |
| BR (1) | BR0109816A (pl) |
| CA (1) | CA2404386A1 (pl) |
| CZ (1) | CZ20023289A3 (pl) |
| DE (1) | DE60103889T2 (pl) |
| DK (1) | DK1282616T3 (pl) |
| EE (1) | EE200200571A (pl) |
| ES (1) | ES2220748T3 (pl) |
| HU (1) | HUP0300427A2 (pl) |
| IL (1) | IL151890A0 (pl) |
| IS (1) | IS6575A (pl) |
| MX (1) | MXPA02009757A (pl) |
| NO (1) | NO20024775L (pl) |
| NZ (1) | NZ522142A (pl) |
| PL (1) | PL357780A1 (pl) |
| PT (1) | PT1282616E (pl) |
| RU (1) | RU2002125495A (pl) |
| SE (1) | SE0001207D0 (pl) |
| SK (1) | SK14232002A3 (pl) |
| WO (1) | WO2001074804A1 (pl) |
| ZA (1) | ZA200207968B (pl) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW548271B (en) | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| SE0101771D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101766D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101769D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101768D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101770D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101765D0 (sv) | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101767D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0101773D0 (sv) * | 2001-05-18 | 2001-05-18 | Astrazeneca Ab | Novel compounds |
| SE0103313D0 (sv) * | 2001-10-03 | 2001-10-03 | Astrazeneca Ab | Novel compounds |
| PL372096A1 (pl) | 2002-01-02 | 2005-07-11 | Ardent Pharmaceuticals, Inc. | Metoda leczenia zaburzeń czynności seksualnych przez związki będące agonistami receptorów delta opioidowych |
| US8476280B2 (en) * | 2002-05-09 | 2013-07-02 | Versi Group, Llc | Compositions and methods for combating lower urinary tract dysfunctions with delta opioid receptor agonists |
| SE0203301D0 (sv) * | 2002-11-07 | 2002-11-07 | Astrazeneca Ab | Novel Compounds |
| SE0300104D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0300103D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0300105D0 (sv) * | 2003-01-16 | 2003-01-16 | Astrazeneca Ab | Diarylmethylidene piperdine derivatives, preparations thereof and uses thereof |
| SE0300987D0 (sv) * | 2003-04-03 | 2003-04-03 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301445D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301441D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| RU2005136524A (ru) * | 2003-05-16 | 2006-06-27 | Астразенека Аб (Se) | Производные диарилметилиденпиперидина, способы их получения и их применение |
| SE0301443D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0301442D0 (sv) * | 2003-05-16 | 2003-05-16 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations therof and uses thereof |
| US7589103B2 (en) * | 2003-06-27 | 2009-09-15 | Janssen Pharmaceutica N.V. | Tricyclic-bridged piperidinylidene derivatives as 8-opioid modulators |
| SE0400026D0 (sv) * | 2004-01-09 | 2004-01-09 | Astrazeneca Ab | Diarylmethylidene piperidine derivatives, preparations thereof and uses thereof |
| SE0402485D0 (sv) | 2004-10-13 | 2004-10-13 | Astrazeneca Ab | Polymorph of N,N-Diethyl-4-(3-Fluorophenyl-Piperidin-4-Ylidene-Methyl)-Benzamide Hydrochloride salt |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2898339A (en) | 1957-07-29 | 1959-08-04 | Wm S Merrell Co | N-substituted benzhydrol, benzhydryl, and benzhydrylidene piperidine |
| US4581171A (en) | 1983-07-27 | 1986-04-08 | Janssen Pharmaceutica, N.V. | [[Bis(aryl)methylene]-1-piperidinyl]alkyl-pyrimidinones useful for treating psychotropic disorders |
| US4816586A (en) | 1987-07-29 | 1989-03-28 | Regents Of The University Of Minnesota | Delta opioid receptor antagonists |
| US5140029A (en) | 1989-01-09 | 1992-08-18 | Janssen Pharmaceutica N.V. | 2-aminopyrimidinone derivatives |
| US4939137A (en) | 1989-06-28 | 1990-07-03 | Ortho Pharmaceutical Corporation | Ring-fused thienopyrimidinedione derivatives |
| US5683998A (en) | 1991-04-23 | 1997-11-04 | Toray Industries, Inc. | Tricyclic triazolo derivatives, processes for producing the same and the uses of the same |
| GB9202238D0 (en) | 1992-02-03 | 1992-03-18 | Wellcome Found | Compounds |
| US5985880A (en) * | 1996-06-05 | 1999-11-16 | Delta Pharmaceuticals | Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds |
| US5574159A (en) | 1992-02-03 | 1996-11-12 | Delta Pharmaceuticals, Inc. | Opioid compounds and methods for making therefor |
| SE9504661D0 (sv) * | 1995-12-22 | 1995-12-22 | Astra Pharma Inc | New compounds |
| TW548271B (en) | 1996-12-20 | 2003-08-21 | Astra Pharma Inc | Novel piperidine derivatives having an exocyclic double bond with analgesic effects |
| CA2316341A1 (en) | 1997-12-24 | 1999-07-08 | Ortho-Mcneil Pharmaceutical, Inc. | 4-[aryl(piperidin-4-yl)] aminobenzamides which bind to the delta-opioid receptor |
-
2000
- 2000-04-04 SE SE0001207A patent/SE0001207D0/xx unknown
-
2001
- 2001-03-28 AR ARP010101477A patent/AR027983A1/es not_active Application Discontinuation
- 2001-03-30 CA CA002404386A patent/CA2404386A1/en not_active Abandoned
- 2001-03-30 CZ CZ20023289A patent/CZ20023289A3/cs unknown
- 2001-03-30 CN CNB018105939A patent/CN1185228C/zh not_active Expired - Fee Related
- 2001-03-30 IL IL15189001A patent/IL151890A0/xx unknown
- 2001-03-30 AT AT01918113T patent/ATE269324T1/de not_active IP Right Cessation
- 2001-03-30 HU HU0300427A patent/HUP0300427A2/hu unknown
- 2001-03-30 KR KR1020027013207A patent/KR20020084285A/ko not_active Withdrawn
- 2001-03-30 WO PCT/SE2001/000707 patent/WO2001074804A1/en not_active Ceased
- 2001-03-30 ES ES01918113T patent/ES2220748T3/es not_active Expired - Lifetime
- 2001-03-30 JP JP2001572494A patent/JP2003529596A/ja active Pending
- 2001-03-30 RU RU2002125495/04A patent/RU2002125495A/ru not_active Application Discontinuation
- 2001-03-30 US US10/240,038 patent/US6756387B2/en not_active Expired - Fee Related
- 2001-03-30 EE EEP200200571A patent/EE200200571A/xx unknown
- 2001-03-30 MX MXPA02009757A patent/MXPA02009757A/es unknown
- 2001-03-30 SK SK1423-2002A patent/SK14232002A3/sk not_active Application Discontinuation
- 2001-03-30 PL PL01357780A patent/PL357780A1/pl not_active Application Discontinuation
- 2001-03-30 AU AU2001244981A patent/AU2001244981A1/en not_active Abandoned
- 2001-03-30 EP EP01918113A patent/EP1282616B1/en not_active Expired - Lifetime
- 2001-03-30 PT PT01918113T patent/PT1282616E/pt unknown
- 2001-03-30 NZ NZ522142A patent/NZ522142A/en unknown
- 2001-03-30 BR BR0109816-0A patent/BR0109816A/pt not_active IP Right Cessation
- 2001-03-30 DK DK01918113T patent/DK1282616T3/da active
- 2001-03-30 DE DE60103889T patent/DE60103889T2/de not_active Expired - Fee Related
-
2002
- 2002-09-30 IS IS6575A patent/IS6575A/is unknown
- 2002-10-03 ZA ZA200207968A patent/ZA200207968B/en unknown
- 2002-10-03 NO NO20024775A patent/NO20024775L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| PT1282616E (pt) | 2004-10-29 |
| CN1432009A (zh) | 2003-07-23 |
| CN1185228C (zh) | 2005-01-19 |
| EP1282616A1 (en) | 2003-02-12 |
| ZA200207968B (en) | 2004-04-07 |
| KR20020084285A (ko) | 2002-11-04 |
| NO20024775L (no) | 2002-12-03 |
| DE60103889D1 (de) | 2004-07-22 |
| HUP0300427A2 (hu) | 2003-06-28 |
| CZ20023289A3 (cs) | 2003-03-12 |
| US20030187022A1 (en) | 2003-10-02 |
| IL151890A0 (en) | 2003-04-10 |
| EP1282616B1 (en) | 2004-06-16 |
| WO2001074804A1 (en) | 2001-10-11 |
| AU2001244981A1 (en) | 2001-10-15 |
| NZ522142A (en) | 2004-06-25 |
| JP2003529596A (ja) | 2003-10-07 |
| IS6575A (is) | 2002-09-30 |
| ATE269324T1 (de) | 2004-07-15 |
| DE60103889T2 (de) | 2005-08-25 |
| SK14232002A3 (sk) | 2003-06-03 |
| BR0109816A (pt) | 2003-01-21 |
| DK1282616T3 (da) | 2004-09-20 |
| AR027983A1 (es) | 2003-04-23 |
| US6756387B2 (en) | 2004-06-29 |
| MXPA02009757A (es) | 2003-05-27 |
| ES2220748T3 (es) | 2004-12-16 |
| RU2002125495A (ru) | 2004-04-10 |
| SE0001207D0 (sv) | 2000-04-04 |
| EE200200571A (et) | 2004-04-15 |
| HK1051690A1 (en) | 2003-08-15 |
| CA2404386A1 (en) | 2001-10-11 |
| NO20024775D0 (no) | 2002-10-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IL196301A0 (en) | Medicament for the treatment of hapatitis c | |
| GB0023983D0 (en) | Therapeutic compounds | |
| GB0008710D0 (en) | Therapeutic compounds | |
| GB0016681D0 (en) | Therapeutic compounds | |
| GB0003397D0 (en) | Therapeutic agents | |
| IL151890A0 (en) | Hydroxyphenyl-piperidin 4-ylidene-methyl-benzamide derivatives for the treatment of pain | |
| GB0013383D0 (en) | Therapeutic benzamide derivatives | |
| PL355101A1 (pl) | Zastosowanie antagonisty H 1 i bezpiecznego steroidu do leczenia chorób oczu | |
| IL151765A0 (en) | Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain | |
| GB0013346D0 (en) | Therapeutic benzamide derivatives | |
| GB0028583D0 (en) | Therapeutic compounds | |
| IL151891A0 (en) | Quinolinyl-piperidin 4-ylidene-methyl-benzamide derivatives for the treatment of pain | |
| CA91213S (en) | Rollator | |
| PL352409A1 (en) | Derivatives of 1-trifluorometyl-4-hydroxy-7-piperidinyl-aminomethylochromane | |
| PL350963A1 (en) | Use of arylalkanoylpyridazines | |
| SI1282616T1 (en) | Hydroxyphenyl-piperidin-4-ylidene-methyl-benzamide derivatives for the treatement of pain | |
| GB0013105D0 (en) | Therapeutic compounds | |
| GB0021927D0 (en) | Use of pharmaceutical combination | |
| PL340617A1 (en) | Derivatives of 2-acylpyridine | |
| HK1051687A (en) | Hydroxyphenyl-piperazinyl-methyl-benzamide derivatives for the treatment of pain | |
| GB0001615D0 (en) | Therapeutic heterocycles | |
| GB0001624D0 (en) | Therapeutic heterocycles | |
| GB0005551D0 (en) | Therapeutic heterocycles | |
| GB0005550D0 (en) | Therapeutic heterocycles | |
| GB0013386D0 (en) | Therapeutic benzamide derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |