PL3597738T3 - Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu - Google Patents

Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu

Info

Publication number
PL3597738T3
PL3597738T3 PL19742120.9T PL19742120T PL3597738T3 PL 3597738 T3 PL3597738 T3 PL 3597738T3 PL 19742120 T PL19742120 T PL 19742120T PL 3597738 T3 PL3597738 T3 PL 3597738T3
Authority
PL
Poland
Prior art keywords
homoserine
derived
amino acid
producing
modified
Prior art date
Application number
PL19742120.9T
Other languages
English (en)
Inventor
Hyo Jin Kim
Lan HUH
Sang Jo Lim
Hyun Ah Kim
Hyung Joon Kim
Chang Il Seo
Seung Bin Lee
Ji Sun Lee
Original Assignee
Cj Cheiljedang Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cj Cheiljedang Corporation filed Critical Cj Cheiljedang Corporation
Publication of PL3597738T3 publication Critical patent/PL3597738T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y101/00—Oxidoreductases acting on the CH-OH group of donors (1.1)
    • C12Y101/01—Oxidoreductases acting on the CH-OH group of donors (1.1) with NAD+ or NADP+ as acceptor (1.1.1)
    • C12Y101/01003—Homoserine dehydrogenase (1.1.1.3)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
PL19742120.9T 2018-05-28 2019-05-21 Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu PL3597738T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180060445A KR101947959B1 (ko) 2018-05-28 2018-05-28 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법
PCT/KR2019/006083 WO2019231159A1 (ko) 2018-05-28 2019-05-21 변이형 호모세린 디하이드로게나제 및 이를 이용한 호모세린 또는 호모세린 유래 l-아미노산의 생산 방법

Publications (1)

Publication Number Publication Date
PL3597738T3 true PL3597738T3 (pl) 2023-07-17

Family

ID=65366474

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19742120.9T PL3597738T3 (pl) 2018-05-28 2019-05-21 Zmodyfikowana dehydrogenaza homoseryny i sposób wytwarzania homoseryny lub l-aminokwasu będącego pochodną homoseryny przy jej użyciu

Country Status (21)

Country Link
US (2) US11236374B2 (pl)
EP (1) EP3597738B1 (pl)
JP (1) JP6938795B2 (pl)
KR (1) KR101947959B1 (pl)
CN (2) CN110945121B (pl)
AR (1) AR115415A1 (pl)
AU (1) AU2019279282B2 (pl)
BR (1) BR112019020697B1 (pl)
CA (1) CA3091741C (pl)
ES (1) ES2944588T3 (pl)
HU (1) HUE062601T2 (pl)
MX (1) MX2020007591A (pl)
MY (1) MY206036A (pl)
PH (1) PH12020551031A1 (pl)
PL (1) PL3597738T3 (pl)
RU (1) RU2733426C1 (pl)
SA (1) SA520420007B1 (pl)
SG (1) SG11202006718YA (pl)
TW (1) TWI740150B (pl)
WO (1) WO2019231159A1 (pl)
ZA (1) ZA202004021B (pl)

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KR102175112B1 (ko) 2019-04-22 2020-11-06 씨제이제일제당 주식회사 L-쓰레오닌 생산능이 강화된 미생물 및 이를 이용한 쓰레오닌 생산방법
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KR102363913B1 (ko) * 2020-06-26 2022-02-18 씨제이제일제당 (주) L-쓰레오닌 디하이드라타아제의 신규 변이체 및 이를 이용한 l-이소류신 생산 방법
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WO2025183467A1 (ko) 2024-02-28 2025-09-04 씨제이제일제당 (주) 에드워드시엘라 탈다 유래 니코틴아미드 뉴클레오티드 트랜스하이드로게나제를 포함하는 미생물 및 이를 이용하여 ｌ-아미노산 또는 그 유도체를 생산하는 방법
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KR102935766B1 (ko) 2024-03-13 2026-03-06 씨제이제일제당 (주) 신규한 프로모터 및 이의 용도
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Also Published As

Publication number Publication date
EP3597738B1 (en) 2023-04-05
CN110945121A (zh) 2020-03-31
MX2020007591A (es) 2021-01-15
MY206036A (en) 2024-11-26
TWI740150B (zh) 2021-09-21
US11236374B2 (en) 2022-02-01
US11555213B2 (en) 2023-01-17
TW202000914A (zh) 2020-01-01
WO2019231159A1 (ko) 2019-12-05
ZA202004021B (en) 2021-09-29
US20210403962A1 (en) 2021-12-30
EP3597738A1 (en) 2020-01-22
BR112019020697B1 (pt) 2022-04-26
US20210002682A1 (en) 2021-01-07
KR101947959B1 (ko) 2019-02-13
EP3597738A4 (en) 2021-01-27
ES2944588T3 (es) 2023-06-22
AU2019279282A1 (en) 2020-07-16
JP2021513341A (ja) 2021-05-27
CN112143719B (zh) 2023-11-24
BR112019020697A2 (pt) 2021-02-17
HUE062601T2 (hu) 2023-11-28
JP6938795B2 (ja) 2021-09-22
CN112143719A (zh) 2020-12-29
RU2733426C1 (ru) 2020-10-01
CN110945121B (zh) 2021-09-28
SG11202006718YA (en) 2020-08-28
SA520420007B1 (ar) 2024-02-29
AU2019279282B2 (en) 2022-03-03
AR115415A1 (es) 2021-01-13
CA3091741A1 (en) 2019-12-05
CA3091741C (en) 2023-10-31
PH12020551031A1 (en) 2021-08-16

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