PL360248A1 - Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof - Google Patents

Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof

Info

Publication number: PL360248A1
Authority: PL; Poland
Prior art keywords: compounds; production; methods; medicaments containing; bicyclic heterocycles
Prior art date: 2000-08-26

Application number

PL36024801A

Other languages

Polish (pl)

Inventor

Frank Himmelsbach

Elke Langkopf

Birgit Jung

Stefan Blech

Flavio Solca

Original Assignee

Boehringer Ingelheim Pharma Gmbh & Co.Kg

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-08-26

Filing date

2001-08-18

Publication date

2004-09-06

2001-08-18 Application filed by Boehringer Ingelheim Pharma Gmbh & Co.Kg filed Critical Boehringer Ingelheim Pharma Gmbh & Co.Kg

2004-09-06 Publication of PL360248A1 publication Critical patent/PL360248A1/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Dermatology (AREA)
Immunology (AREA)
Gastroenterology & Hepatology (AREA)
Oncology (AREA)
Urology & Nephrology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

PL36024801A 2000-08-26 2001-08-18 Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof PL360248A1 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE10042058A DE10042058A1 (en)	2000-08-26	2000-08-26	Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
PCT/EP2001/009532 WO2002018351A1 (en)	2000-08-26	2001-08-18	Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof

Publications (1)

Publication Number	Publication Date
PL360248A1 true PL360248A1 (en)	2004-09-06

Family

ID=7653945

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL36024801A PL360248A1 (en)	2000-08-26	2001-08-18	Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof

Country Status (30)

Country	Link
EP (1)	EP1315705A1 (en)
JP (1)	JP4834282B2 (en)
KR (1)	KR100862873B1 (en)
CN (1)	CN100404517C (en)
AR (1)	AR033562A1 (en)
AU (2)	AU8769401A (en)
BG (1)	BG107559A (en)
BR (1)	BR0113519A (en)
CA (1)	CA2417897C (en)
CZ (1)	CZ302567B6 (en)
DE (1)	DE10042058A1 (en)
EA (1)	EA005679B1 (en)
EC (1)	ECSP034464A (en)
EE (1)	EE05269B1 (en)
HR (1)	HRP20030138A2 (en)
HU (1)	HUP0300819A3 (en)
IL (2)	IL154602A0 (en)
ME (1)	MEP58708A (en)
MX (1)	MXPA03001483A (en)
MY (1)	MY126132A (en)
NO (1)	NO324866B1 (en)
NZ (1)	NZ524668A (en)
PL (1)	PL360248A1 (en)
RS (1)	RS52279B (en)
SK (1)	SK287747B6 (en)
TW (1)	TWI294422B (en)
UA (1)	UA73004C2 (en)
UY (1)	UY26903A1 (en)
WO (1)	WO2002018351A1 (en)
ZA (1)	ZA200300991B (en)

Families Citing this family (41)

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EE04748B1 (en)	1999-06-21	2006-12-15	Boehringer Ingelheim Pharma Kg	Bicyclic heterocyclic compounds, drugs containing these compounds, their use and methods for their preparation
DE10042059A1 (en) *	2000-08-26	2002-03-07	Boehringer Ingelheim Pharma	Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
US7019012B2 (en)	2000-12-20	2006-03-28	Boehringer Ingelheim International Pharma Gmbh & Co. Kg	Quinazoline derivatives and pharmaceutical compositions containing them
TWI324597B (en)	2002-03-28	2010-05-11	Astrazeneca Ab	Quinazoline derivatives
US6924285B2 (en)	2002-03-30	2005-08-02	Boehringer Ingelheim Pharma Gmbh & Co.	Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
CA2476008C (en) *	2002-03-30	2011-12-13	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Bicyclic heterocyclic compounds, pharmaceutical compositions containing these compounds, their use and process for preparing them
DE10214412A1 (en) *	2002-03-30	2003-10-09	Boehringer Ingelheim Pharma	Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and process for their preparation
EP2280003B1 (en)	2002-07-15	2014-04-02	Symphony Evolution, Inc.	Process for preparing receptor-type kinase modulators
DE10326186A1 (en) *	2003-06-06	2004-12-23	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
DE10334226A1 (en) *	2003-07-28	2005-02-17	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Use of tyrosine kinase inhibitors for the treatment of inflammatory processes
GB0317665D0 (en)	2003-07-29	2003-09-03	Astrazeneca Ab	Qinazoline derivatives
ES2305844T3 (en)	2003-09-16	2008-11-01	Astrazeneca Ab	DERIVATIVES OF QUINAZOLINE AS INHIBITORS OF THYROSINE KINASE.
WO2005028469A1 (en)	2003-09-19	2005-03-31	Astrazeneca Ab	Quinazoline derivatives
PT2213661E (en)	2003-09-26	2011-12-15	Exelixis Inc	C-met modulators and methods of use
US7456189B2 (en)	2003-09-30	2008-11-25	Boehringer Ingelheim International Gmbh	Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation
DE10345875A1 (en) *	2003-09-30	2005-04-21	Boehringer Ingelheim Pharma	Bicyclic heterocycles, pharmaceutical compositions containing them, their use and methods of preparation
DE10350717A1 (en) *	2003-10-30	2005-06-02	Boehringer Ingelheim Pharma Gmbh & Co. Kg	Use of tyrosine kinase inhibitors for the treatment of inflammatory processes
US20060035893A1 (en)	2004-08-07	2006-02-16	Boehringer Ingelheim International Gmbh	Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
PE20060777A1 (en)	2004-12-24	2006-10-06	Boehringer Ingelheim Int	INDOLINONE DERIVATIVES FOR THE TREATMENT OR PREVENTION OF FIBROTIC DISEASES
MX2007010399A (en)	2005-02-26	2007-09-25	Astrazeneca Ab	Quinazoline derivatives as tyrosine kinase inhibitors.
KR100673775B1 (en) *	2005-04-08	2007-01-24	엘지전자 주식회사	Refrigerator Home Bar
CA2619037A1 (en) *	2005-08-22	2007-03-01	Boehringer Ingelheim International Gmbh	Bicyclic heterocycles medicaments comprising said compounds use and method for production thereof
CA2833706C (en)	2005-11-11	2014-10-21	Boehringer Ingelheim International Gmbh	Quinazoline derivatives for the treatment of cancer diseases
WO2007101782A1 (en) *	2006-03-09	2007-09-13	Boehringer Ingelheim International Gmbh	Bicyclic heterocycles, medicaments containing these compounds, their use and process for preparing them
AU2007299080B2 (en)	2006-09-18	2013-04-18	Boehringer Ingelheim International Gmbh	Method for treating cancer harboring EGFR mutations
EP1921070A1 (en)	2006-11-10	2008-05-14	Boehringer Ingelheim Pharma GmbH & Co. KG	Bicyclic heterocycles, medicaments comprising them, their use and process for their preparation
EP2118075A1 (en)	2007-02-06	2009-11-18	Boehringer Ingelheim International GmbH	Bicyclic heterocycles, drugs containing said compounds, use thereof, and method for production thereof
CA2711582A1 (en)	2008-02-07	2009-08-13	Boehringer Ingelheim International Gmbh	Spirocyclic heterocycles, formulations containing said compounds, use thereof and processes for the preparation thereof
EP2303276B1 (en)	2008-05-13	2013-11-13	AstraZeneca AB	Fumarate salt of 4-(3-chloro-2-fluoroanilino)-7-methoxy-6-{[1-(n-methylcarbamoylmethyl)piperidin-4-yl]oxy}quinazoline
CA2733153C (en)	2008-08-08	2016-11-08	Boehringer Ingelheim International Gmbh	Cyclohexyloxy substituted heterocycles, pharmaceutical compositions containing these compounds and processes for preparing them
SG173014A1 (en)	2009-01-16	2011-08-29	Exelixis Inc	Malate salt of n- (4- { [ 6, 7-bis (methyloxy) quin0lin-4-yl] oxy}phenyl)-n' - (4 -fluorophenyl) cyclopropane-1,1-dicarboxamide, and crystalline forms therof for the treatment of cancer
PL2451445T3 (en)	2009-07-06	2019-09-30	Boehringer Ingelheim International Gmbh	Process for drying of bibw2992, of its salts and of solid pharmaceutical formulations comprising this active ingredient
UA108618C2 (en)	2009-08-07	2015-05-25		APPLICATION OF C-MET-MODULATORS IN COMBINATION WITH THEMOSOLOMID AND / OR RADIATION THERAPY FOR CANCER TREATMENT
KR101317809B1 (en)	2011-06-07	2013-10-16	한미약품 주식회사	Pharmaceutical composition comprising amide derivative inhibiting the growth of cancer cell and non-metalic salt lubricant
KR20140096571A (en)	2013-01-28	2014-08-06	한미약품 주식회사	Method for preparing 1-(4-(4-(3,4-dichloro-2-fluorophenylamino)-7-methoxyquinazolin-6-yloxy)piperidin-1-yl)prop-2-en-1-one
CN105209456B (en)	2013-03-06	2018-05-08	阿斯利康(瑞典)有限公司	The quinazoline inhibitor of the activated mutated forms of EGF-R ELISA
US9242965B2 (en)	2013-12-31	2016-01-26	Boehringer Ingelheim International Gmbh	Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
RS60017B1 (en) *	2014-04-04	2020-04-30	H Lundbeck As	Halogenated quinazolin-thf-amines as pde1 inhibitors
US20170176028A1 (en)	2015-12-18	2017-06-22	Lg Electronics Inc.	Air conditioner
MA46852A (en)	2016-11-17	2019-09-25	Univ Texas	COMPOUNDS WITH ANTITUMOR ACTIVITY AGAINST CANCER CELLS CARRIER OF EGFR OR HER2 MUTATIONS EXON 20
CN112321814B (en) *	2020-12-30	2021-03-23	广州初曲科技有限公司	Preparation and application of gefitinib idebenone conjugate

Family Cites Families (8)

* Cited by examiner, † Cited by third party
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GB9508538D0 (en) *	1995-04-27	1995-06-14	Zeneca Ltd	Quinazoline derivatives
GB9624482D0 (en) *	1995-12-18	1997-01-15	Zeneca Phaema S A	Chemical compounds
BR9707495A (en) *	1996-02-13	1999-07-27	Zeneca Ltd	Quinazoline derivative process for the preparation of the same pharmaceutical composition and process for the production of an antiangiogenic effect and / or reduction of vascular permeability in a warm-blooded animal
GB9603095D0 (en) *	1996-02-14	1996-04-10	Zeneca Ltd	Quinazoline derivatives
US6291455B1 (en) *	1996-03-05	2001-09-18	Zeneca Limited	4-anilinoquinazoline derivatives
HU228446B1 (en) *	1996-04-12	2013-03-28	Warner Lambert Co	Kinazoline derivatives as irreversible inhibitors of protein-kinase, pharmaceutical compositions containing these compounds and use thereof
GB9718972D0 (en) *	1996-09-25	1997-11-12	Zeneca Ltd	Chemical compounds
DE19911509A1 (en) *	1999-03-15	2000-09-21	Boehringer Ingelheim Pharma	Bicyclic heterocycles, medicaments containing these compounds, their use and processes for their preparation

2000
- 2000-08-26 DE DE10042058A patent/DE10042058A1/en not_active Ceased
2001
- 2001-08-18 HR HR20030138A patent/HRP20030138A2/en not_active Application Discontinuation
- 2001-08-18 MX MXPA03001483A patent/MXPA03001483A/en active IP Right Grant
- 2001-08-18 UA UA2003032533A patent/UA73004C2/en unknown
- 2001-08-18 EA EA200300219A patent/EA005679B1/en not_active IP Right Cessation
- 2001-08-18 CA CA002417897A patent/CA2417897C/en not_active Expired - Fee Related
- 2001-08-18 HU HU0300819A patent/HUP0300819A3/en unknown
- 2001-08-18 EE EEP200300077A patent/EE05269B1/en not_active IP Right Cessation
- 2001-08-18 AU AU8769401A patent/AU8769401A/en active Pending
- 2001-08-18 RS YU14003A patent/RS52279B/en unknown
- 2001-08-18 BR BR0113519-8A patent/BR0113519A/en not_active Application Discontinuation
- 2001-08-18 WO PCT/EP2001/009532 patent/WO2002018351A1/en not_active Ceased
- 2001-08-18 JP JP2002523469A patent/JP4834282B2/en not_active Expired - Fee Related
- 2001-08-18 KR KR1020037002744A patent/KR100862873B1/en not_active Expired - Fee Related
- 2001-08-18 EP EP01967285A patent/EP1315705A1/en not_active Ceased
- 2001-08-18 PL PL36024801A patent/PL360248A1/en not_active Application Discontinuation
- 2001-08-18 AU AU2001287694A patent/AU2001287694B2/en not_active Ceased
- 2001-08-18 ME MEP-587/08A patent/MEP58708A/en unknown
- 2001-08-18 IL IL15460201A patent/IL154602A0/en unknown
- 2001-08-18 NZ NZ524668A patent/NZ524668A/en not_active IP Right Cessation
- 2001-08-18 CN CNB01814635XA patent/CN100404517C/en not_active Expired - Fee Related
- 2001-08-18 CZ CZ20030870A patent/CZ302567B6/en not_active IP Right Cessation
- 2001-08-18 SK SK231-2003A patent/SK287747B6/en not_active IP Right Cessation
- 2001-08-23 UY UY26903A patent/UY26903A1/en not_active Application Discontinuation
- 2001-08-24 AR ARP010104041A patent/AR033562A1/en unknown
- 2001-08-24 MY MYPI20013985A patent/MY126132A/en unknown
- 2001-08-24 TW TW090120905A patent/TWI294422B/en not_active IP Right Cessation
2003
- 2003-02-03 EC EC2003004464A patent/ECSP034464A/en unknown
- 2003-02-05 ZA ZA200300991A patent/ZA200300991B/en unknown
- 2003-02-14 BG BG107559A patent/BG107559A/en unknown
- 2003-02-24 IL IL154602A patent/IL154602A/en not_active IP Right Cessation
- 2003-02-25 NO NO20030870A patent/NO324866B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR20030024914A (en)	2003-03-26
NO20030870L (en)	2003-02-25
HUP0300819A2 (en)	2003-09-29
CN1449390A (en)	2003-10-15
KR100862873B1 (en)	2008-10-15
EA005679B1 (en)	2005-04-28
NO324866B1 (en)	2007-12-17
AU2001287694B2 (en)	2007-09-06
EE200300077A (en)	2004-12-15
AU8769401A (en)	2002-03-13
EE05269B1 (en)	2010-02-15
RS52279B (en)	2012-10-31
IL154602A (en)	2008-07-08
MY126132A (en)	2006-09-29
CA2417897C (en)	2009-03-31
IL154602A0 (en)	2003-09-17
WO2002018351A1 (en)	2002-03-07
CN100404517C (en)	2008-07-23
NO20030870D0 (en)	2003-02-25
SK287747B6 (en)	2011-08-04
SK2312003A3 (en)	2003-10-07
HK1057557A1 (en)	2004-04-08
AR033562A1 (en)	2003-12-26
MEP58708A (en)	2011-05-10
MXPA03001483A (en)	2003-06-06
EP1315705A1 (en)	2003-06-04
CZ302567B6 (en)	2011-07-13
TWI294422B (en)	2008-03-11
UY26903A1 (en)	2002-03-22
ZA200300991B (en)	2004-04-16
NZ524668A (en)	2006-06-30
UA73004C2 (en)	2005-05-16
HUP0300819A3 (en)	2008-03-28
YU14003A (en)	2006-01-16
BR0113519A (en)	2003-07-01
ECSP034464A (en)	2003-03-31
DE10042058A1 (en)	2002-03-07
HRP20030138A2 (en)	2005-04-30
JP2004507529A (en)	2004-03-11
BG107559A (en)	2003-10-31
CA2417897A1 (en)	2003-01-30
JP4834282B2 (en)	2011-12-14
EA200300219A1 (en)	2003-08-28

Legal Events

Date	Code	Title	Description
2013-03-29	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
HUP0300819A3 (en)	2008-03-28	Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof
IL147133A0 (en)	2002-08-14	Bicyclic heterocycles, medicaments containing these compounds, their use and methods for the production thereof
AU2001295481A1 (en)	2002-03-13	Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof
AU2001287694A1 (en)	2002-06-06	Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof
MXPA03001510A (en)	2003-06-09	Bicyclic heterocycles, medicaments containing these compounds, their use, and methods for the production thereof.
IL156552A0 (en)	2004-01-04	Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
AU6383101A (en)	2001-10-23	Bicyclic heterocylces, medicaments containing said compounds, the use thereof and method for producing them
HRP20030501A2 (en)	2005-04-30	Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use
MXPA03000873A (en)	2003-06-06	Quinazoline derivatives, medicaments containing these compounds, their use, and methods for the production thereof.
HUS1400005I1 (en)	2017-08-28	Quinazoline derivatives, medicaments containing said compounds, their utilization and method for the production thereof
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