PL361061A1 - Postacie krystaliczne fluwastatyny sodowej - Google Patents

Postacie krystaliczne fluwastatyny sodowej

Info

Publication number: PL361061A1
Authority: PL; Poland
Prior art keywords: crystalline forms; fluvastatin sodium; fluvastatin; forms; crystalline
Prior art date: 2000-10-31

Application number

PL01361061A

Other languages

English (en)

Inventor

Der Schaaf Paul Adriaan Van

Heinz Wolleb

Annemarie Wolleb

Claudia Marcolli

Martin Szelagiewicz

Andreas Burkhard

Beat Freiermuth

Original Assignee

Ciba Specialty Chemicals Holding Inc.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-31

Filing date

2001-10-23

Publication date

2004-09-20

2001-10-23 Application filed by Ciba Specialty Chemicals Holding Inc. filed Critical Ciba Specialty Chemicals Holding Inc.

2004-09-20 Publication of PL361061A1 publication Critical patent/PL361061A1/pl

Links

ZGGHKIMDNBDHJB-NRFPMOEYSA-M (3R,5S)-fluvastatin sodium Chemical compound [Na+].C12=CC=CC=C2N(C(C)C)C(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)=C1C1=CC=C(F)C=C1 ZGGHKIMDNBDHJB-NRFPMOEYSA-M 0.000 title 1
229960000868 fluvastatin sodium Drugs 0.000 title 1
FJLGEFLZQAZZCD-MCBHFWOFSA-N (3R,5S)-fluvastatin Chemical compound C12=CC=CC=C2N(C(C)C)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C1C1=CC=C(F)C=C1 FJLGEFLZQAZZCD-MCBHFWOFSA-N 0.000 abstract 1
229960003765 fluvastatin Drugs 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)

PL01361061A 2000-10-31 2001-10-23 Postacie krystaliczne fluwastatyny sodowej PL361061A1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00811013		2000-10-31
PCT/EP2001/012239 WO2002036563A1 (en)	2000-10-31	2001-10-23	Crystalline forms of fluvastatin sodium

Publications (1)

Publication Number	Publication Date
PL361061A1 true PL361061A1 (pl)	2004-09-20

Family

ID=8175001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL01361061A PL361061A1 (pl)	2000-10-31	2001-10-23	Postacie krystaliczne fluwastatyny sodowej

Country Status (11)

Country	Link
US (1)	US6858643B2 (pl)
EP (1)	EP1330435B1 (pl)
JP (1)	JP2004513112A (pl)
CN (1)	CN1210260C (pl)
AT (1)	ATE302756T1 (pl)
AU (2)	AU2002223639B2 (pl)
CA (1)	CA2426395A1 (pl)
DE (1)	DE60112956T2 (pl)
ES (1)	ES2247193T3 (pl)
PL (1)	PL361061A1 (pl)
WO (1)	WO2002036563A1 (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL159861A0 (en) *	2001-08-03	2004-06-20	Ciba Sc Holding Ag	Crystalline forms of fluvastatin sodium
ATE409476T1 (de) *	2002-06-13	2008-10-15	Novartis Pharma Gmbh	Calciumsalze von statinen aus indol
AU2003250086A1 (en) *	2002-07-26	2004-02-23	Ciba Specialty Chemicals Holging Inc.	Crystalline polymorphic and amorphous forms of benazepril hydrochloride
DE10316087A1 (de) *	2003-04-08	2004-11-11	Ratiopharm Gmbh	Polymorphstabilisierung von Fluvastatin-Natrium in Pharmazeutischen Formulierungen
WO2004096765A2 (en) *	2003-05-01	2004-11-11	Morepen Laboratories Ltd.	A novel crystalline polymorph of fluvastatin sodium and a process for preparing it
JP4037898B2 (ja) *	2003-06-18	2008-01-23	テバファーマシューティカルインダストリーズリミティド	フルバスタチンナトリウム結晶形ｘｉｖ、ｌｘｘｉｉｉ、ｌｘｘｉｘ、ｌｘｘｘ及びｘｘｘｖｉｉ型、それらの調製方法、それらを含有する組成物及びそれらの使用方法
US7368468B2 (en)	2003-06-18	2008-05-06	Teva Pharmaceutical Industries Ltd.	Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
US7368581B2 (en)	2003-06-18	2008-05-06	Teva Pharmaceutical Industries Ltd.	Process for the preparation of fluvastatin sodium crystal from XIV
WO2005037787A1 (en) *	2003-10-16	2005-04-28	Ciba Specialty Chemicals Holding Inc.	Crystalline form of fluvastatin sodium
WO2006021967A1 (en) *	2004-08-26	2006-03-02	Biocon Limited	Process for the preparation of fluvastatin sodium form a.
EP1634870A1 (en) *	2004-08-27	2006-03-15	Zhejiang Hisun Pharmaceutical Co. Ltd.	Process and intermediates for the selective synthesis of Fluvastatin
US8115013B2 (en)	2004-10-05	2012-02-14	Biocon Limited	Process for the preparation of amorphous fluvastatin sodium
WO2006085338A2 (en) *	2005-02-11	2006-08-17	Jubilant Organosys Limited	Novel polymorphic forms of fluvastatin sodium and process for preparing the same
WO2006109147A1 (en) *	2005-04-12	2006-10-19	Glenmark Pharmaceuticals Limited	Substantially pure amorphous fluvastatin, processes for its preparation and pharmaceutical compositions containing same
JP2007246522A (ja) *	2006-02-27	2007-09-27	Teva Pharmaceutical Industries Ltd	フルバスタチンナトリウムの新規形及びその調製方法
CL2008000684A1 (es)	2007-03-09	2008-08-01	Indigene Pharmaceuticals Inc	Composicion farmaceutica que comprende metformina r-(+) lipoato y un inhibidor de reductasa hmg-coa; formulacion de dosis unitaria; y uso en el tratamiento de una complicacion diabetica.
US20110112053A1 (en) *	2008-04-16	2011-05-12	University Of Utah Research Foundation	Pharmacological targeting of vascular malformations
CA2811009A1 (en) *	2010-09-17	2012-03-22	Abbvie Inc.	Raman spectroscopy for bioprocess operations
CN102351776B (zh) *	2011-09-20	2012-09-26	海南美大制药有限公司	一种氟伐他汀钠化合物及其制法
BR112015016282A2 (en) *	2013-01-07	2017-07-11	Arog Pharmaceuticals, Inc.	crenolanib for treatment of mutated flt3 proliferative disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4739073A (en) *	1983-11-04	1988-04-19	Sandoz Pharmaceuticals Corp.	Intermediates in the synthesis of indole analogs of mevalonolactone and derivatives thereof
WO1997049681A1 (en)	1996-06-24	1997-12-31	Astra Aktiebolag (Publ)	Polymorphic compounds

2001
- 2001-10-23 US US10/130,043 patent/US6858643B2/en not_active Expired - Fee Related
- 2001-10-23 AT AT01992698T patent/ATE302756T1/de not_active IP Right Cessation
- 2001-10-23 ES ES01992698T patent/ES2247193T3/es not_active Expired - Lifetime
- 2001-10-23 WO PCT/EP2001/012239 patent/WO2002036563A1/en not_active Ceased
- 2001-10-23 JP JP2002539323A patent/JP2004513112A/ja not_active Withdrawn
- 2001-10-23 DE DE60112956T patent/DE60112956T2/de not_active Expired - Fee Related
- 2001-10-23 AU AU2002223639A patent/AU2002223639B2/en not_active Ceased
- 2001-10-23 CA CA002426395A patent/CA2426395A1/en not_active Abandoned
- 2001-10-23 PL PL01361061A patent/PL361061A1/pl not_active Application Discontinuation
- 2001-10-23 EP EP01992698A patent/EP1330435B1/en not_active Expired - Lifetime
- 2001-10-23 CN CNB01818278XA patent/CN1210260C/zh not_active Expired - Fee Related
- 2001-10-23 AU AU2363902A patent/AU2363902A/xx active Pending

Also Published As

Publication number	Publication date
DE60112956D1 (de)	2005-09-29
ES2247193T3 (es)	2006-03-01
US6858643B2 (en)	2005-02-22
CN1473151A (zh)	2004-02-04
EP1330435B1 (en)	2005-08-24
EP1330435A1 (en)	2003-07-30
DE60112956T2 (de)	2006-06-14
ATE302756T1 (de)	2005-09-15
CA2426395A1 (en)	2002-05-10
JP2004513112A (ja)	2004-04-30
CN1210260C (zh)	2005-07-13
US20030125569A1 (en)	2003-07-03
AU2363902A (en)	2002-05-15
AU2002223639B2 (en)	2006-06-22
WO2002036563A1 (en)	2002-05-10

Similar Documents

Publication	Publication Date	Title
AU2363902A (en)	2002-05-15	Crystalline forms of fluvastatin sodium
PL370292A1 (pl)	2005-05-16	Preparaty
MXPA05013752A (es)	2006-03-08	Procedimiento e intermediarios para la preparacion de (1r,2s,5s)-6,6-dimetil-3-azabiciclo[3,1,0]exan-2-carboxilatos o sales de los mismos.
GB0114286D0 (en)	2001-08-01	Nucleoside Derivatives
CA2431068A1 (en)	2002-07-04	Crystalline forms of atorvastatin
WO2003037860A3 (en)	2004-03-25	Purine analogs having hsp90-inhibiting activity
IL165715A0 (en)	2006-01-15	2-ureido-6-heteroaryl-3h-benzoimidazole-4-carboxylic acid derivatives, pharmaceutical compositions containing the same and methods for the preparation thereof
UA96449C2 (en)	2011-11-10	Stable laquinimod preparations
AU2001276420A1 (en)	2002-01-31	Novel gamma crystalline form of perindopril tert-butylamine salt, preparation method, and pharmaceutical compositions containing same.
WO2004093800A3 (en)	2005-01-06	Thyronamine derivatives and analogs and methods of use thereof
IL164440A0 (en)	2005-12-18	New pharmaceutical composition containing fibanserin polymorph a
AP1787A (en)	2007-10-04	Novel perindopril salt and pharmaceutical compositions containing same.
IL160171A0 (en)	2004-07-25	Depsipeptide derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
WO2004078105A3 (fr)	2004-10-28	Composition de fondaparinux sodique de haute purete
HUP0401141A3 (en)	2011-07-28	Crystalline forms of fluvastatin sodium, process for their preparation and pharmaceutical compositions containing them
AU2003231920A1 (en)	2003-10-13	Antiinfectve compounds, process for their preparation and pharmaceutical compositions containing them
WO2001029066A3 (en)	2001-11-01	Basic monocyclic compounds having nk2 antagonist action, processes for their preparation, and formulations containing them
AP2001002325A0 (en)	2001-12-31	Novel crystalline forms of a macrolide antibiotic
WO2004048381A3 (en)	2004-08-05	Pyrazoloazepine compounds as pharmaceutical agents
MXPA05007253A (es)	2005-12-14	Sales novedosas de derivados anticonvulsivantes.
MY142077A (en)	2010-08-30	Semi-solid systems containing azetidine derivatives
AU2002326391A1 (en)	2003-01-29	Carvedilol polymorph
GB2415377A (en)	2005-12-28	Hepatoprotective pharmaceutical composition comprising a mixture of coumarinolignoids and process for preparation thereof
GB0322994D0 (en)	2003-11-05	Organic compounds
DE69824410D1 (en)	2004-07-15	Antithrombosemittel

Legal Events

Date	Code	Title	Description
2009-04-30	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)