PL3621950T3 - Związki stanowiące modulator trpv1 - Google Patents

Związki stanowiące modulator trpv1

Info

Publication number
PL3621950T3
PL3621950T3 PL18721827T PL18721827T PL3621950T3 PL 3621950 T3 PL3621950 T3 PL 3621950T3 PL 18721827 T PL18721827 T PL 18721827T PL 18721827 T PL18721827 T PL 18721827T PL 3621950 T3 PL3621950 T3 PL 3621950T3
Authority
PL
Poland
Prior art keywords
modulator compounds
trpv1 modulator
trpv1
compounds
modulator
Prior art date
Application number
PL18721827T
Other languages
English (en)
Inventor
Isabel Devesa Giner
Armando GENAZZANI
Tracey Pirali
Asia Fernandez Carvajal
Antonio Vicente Ferrer Montiel
Original Assignee
Antalgenics, S.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antalgenics, S.L. filed Critical Antalgenics, S.L.
Publication of PL3621950T3 publication Critical patent/PL3621950T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/08—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/232—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having three or more double bonds, e.g. etretinate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/06—Preparation of carboxylic acid amides from nitriles by transformation of cyano groups into carboxamide groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Amplitude Modulation (AREA)
PL18721827T 2017-05-11 2018-05-10 Związki stanowiące modulator trpv1 PL3621950T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17382266.9A EP3401307A1 (en) 2017-05-11 2017-05-11 Trpv1 modulator compounds
EP18721827.6A EP3621950B1 (en) 2017-05-11 2018-05-10 Trpv1 modulator compounds
PCT/EP2018/062169 WO2018206742A1 (en) 2017-05-11 2018-05-10 Trpv1 modulator compounds

Publications (1)

Publication Number Publication Date
PL3621950T3 true PL3621950T3 (pl) 2022-04-19

Family

ID=58707459

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18721827T PL3621950T3 (pl) 2017-05-11 2018-05-10 Związki stanowiące modulator trpv1

Country Status (14)

Country Link
US (1) US11274073B2 (pl)
EP (2) EP3401307A1 (pl)
JP (1) JP7245404B2 (pl)
KR (1) KR102649310B1 (pl)
CN (1) CN110621654B (pl)
AU (1) AU2018265460B2 (pl)
DK (1) DK3621950T3 (pl)
ES (1) ES2909024T3 (pl)
HU (1) HUE057959T2 (pl)
PL (1) PL3621950T3 (pl)
PT (1) PT3621950T (pl)
TW (1) TWI780150B (pl)
WO (1) WO2018206742A1 (pl)
ZA (1) ZA201907406B (pl)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023161264A1 (en) 2022-02-23 2023-08-31 Prospera Biotech, S.L. Compositions for treating hyperhidrosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3689557A (en) * 1969-06-09 1972-09-05 American Home Prod Phenethylamides
DE102005023588A1 (de) * 2005-05-18 2006-11-23 Grünenthal GmbH Salze substituierter Allophansäureester und deren Verwendung in Arzneimitteln
WO2007120012A1 (en) * 2006-04-19 2007-10-25 Amorepacific Corporation Novel compounds, isomer thereof, or pharmaceutically acceptable salts thereof as vanilloid receptor antagonist; and pharmaceutical compositions containing the same
JP2010513557A (ja) * 2006-12-20 2010-04-30 アボット・ラボラトリーズ 疼痛治療のためのtrpv1バニロイド受容体アンタゴニストとしてのn−(5,6,7,8−テトラヒドロナフタレン−1−イル)尿素誘導体および関連化合物
WO2010056044A2 (ko) * 2008-11-11 2010-05-20 (주)아모레퍼시픽 바닐로이드 수용체 길항제로 작용하는 신규 화합물, 이의 이성질체 또는 이의 약제학적으로 허용 가능한 염 및 이를 포함하는 약학 조성물
US8343971B2 (en) * 2009-09-15 2013-01-01 Rutgers, The State University Of New Jersey Pharmacologically-active vanilloid carbamates
WO2015160842A1 (en) * 2014-04-14 2015-10-22 Flex Pharma, Inc. Methods and formulatiions of capsaicinoids and capsinoids

Also Published As

Publication number Publication date
EP3621950A1 (en) 2020-03-18
WO2018206742A1 (en) 2018-11-15
US20200199063A1 (en) 2020-06-25
CN110621654A (zh) 2019-12-27
CA3062592A1 (en) 2018-11-15
KR20200007804A (ko) 2020-01-22
JP2020519636A (ja) 2020-07-02
EP3621950B1 (en) 2021-12-15
EP3401307A1 (en) 2018-11-14
ES2909024T3 (es) 2022-05-05
US11274073B2 (en) 2022-03-15
HUE057959T2 (hu) 2022-06-28
CN110621654B (zh) 2022-11-01
KR102649310B1 (ko) 2024-03-19
PT3621950T (pt) 2022-03-10
JP7245404B2 (ja) 2023-03-24
TW201900603A (zh) 2019-01-01
AU2018265460B2 (en) 2022-08-18
DK3621950T3 (da) 2022-03-21
AU2018265460A1 (en) 2019-11-28
ZA201907406B (en) 2021-01-27
TWI780150B (zh) 2022-10-11

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