PL362704A1 - Zmodyfikowany rzęskowy czynnik neurotropowy (CNTF) o obniżonej immunogeniczności - Google Patents

Zmodyfikowany rzęskowy czynnik neurotropowy (CNTF) o obniżonej immunogeniczności

Info

Publication number
PL362704A1
PL362704A1 PL02362704A PL36270402A PL362704A1 PL 362704 A1 PL362704 A1 PL 362704A1 PL 02362704 A PL02362704 A PL 02362704A PL 36270402 A PL36270402 A PL 36270402A PL 362704 A1 PL362704 A1 PL 362704A1
Authority
PL
Poland
Prior art keywords
cntf
neurotrophic factor
reduced immunogenicity
ciliary neurotrophic
modified ciliary
Prior art date
Application number
PL02362704A
Other languages
English (en)
Inventor
Francis J. Carr
Graham Carter
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL362704A1 publication Critical patent/PL362704A1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/185—Nerve growth factor [NGF]; Brain derived neurotrophic factor [BDNF]; Ciliary neurotrophic factor [CNTF]; Glial derived neurotrophic factor [GDNF]; Neurotrophins, e.g. NT-3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Psychology (AREA)
  • Neurosurgery (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL02362704A 2001-03-02 2002-02-27 Zmodyfikowany rzęskowy czynnik neurotropowy (CNTF) o obniżonej immunogeniczności PL362704A1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01105089 2001-03-02
PCT/EP2002/002084 WO2002070698A2 (en) 2001-03-02 2002-02-27 Modified ciliary neurotrophic factor (cntf) with reduced immunogenicity

Publications (1)

Publication Number Publication Date
PL362704A1 true PL362704A1 (pl) 2004-11-02

Family

ID=8176647

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02362704A PL362704A1 (pl) 2001-03-02 2002-02-27 Zmodyfikowany rzęskowy czynnik neurotropowy (CNTF) o obniżonej immunogeniczności

Country Status (13)

Country Link
US (1) US20040087503A1 (pl)
EP (1) EP1379655A2 (pl)
JP (1) JP2004529629A (pl)
KR (1) KR20030081480A (pl)
CN (1) CN1494593A (pl)
BR (1) BR0207705A (pl)
CA (1) CA2439682A1 (pl)
HU (1) HUP0303310A2 (pl)
MX (1) MXPA03007839A (pl)
PL (1) PL362704A1 (pl)
RU (1) RU2003129069A (pl)
WO (1) WO2002070698A2 (pl)
ZA (1) ZA200307678B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050064555A1 (en) * 2003-07-09 2005-03-24 Xencor, Inc. Ciliary neurotrophic factor variants
US20050069987A1 (en) * 2003-09-30 2005-03-31 Daly Thomas J. Modified ciliary neurotrophic factor polypeptides with reduced antigenicity
EP2009103A1 (en) * 2007-03-16 2008-12-31 Ebewe Pharma Ges.m.b.H. Nfg. KG Neurotrophic peptides
US8592374B2 (en) 2007-03-16 2013-11-26 Research Foundation For Mental Hygiene, Inc. Neurotrophic peptides
WO2009014835A2 (en) * 2007-06-21 2009-01-29 Angelica Therapeutics, Inc. Modified toxins
EP2268297A4 (en) * 2008-02-29 2011-11-16 Angelica Therapeutics Inc MODIFIED TOXINS
DE102011104822A1 (de) 2011-06-18 2012-12-20 Christian-Albrechts-Universität Zu Kiel Ciliary-Neutrophic-Factor-Varianten
HK1220376A1 (zh) 2013-03-15 2017-05-05 Angelica Therapeutics, Inc. 修饰的毒素
WO2016077823A2 (en) * 2014-11-14 2016-05-19 D. E. Shaw Research, Llc Suppressing interaction between bonded particles
CA3045925A1 (en) * 2016-12-06 2018-06-14 The Board Of Trustees Of The Leland Stanford Junior University Ciliary neurotrophic factor receptor ligand-binding agents and methods of using the same

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593857A (en) * 1991-08-23 1997-01-14 Scios Inc. Production of homogeneous truncated CNTF
CA2123234A1 (en) * 1991-11-11 1993-05-27 Lanfranco Callegaro Synthesis and purification of truncated and mutein forms of human ciliary neuronotrophic factor
US5939534A (en) * 1993-12-29 1999-08-17 Sumitomo Pharmaceuticals Company, Limited Factors mutated in the D1 cap region
IT1288388B1 (it) * 1996-11-19 1998-09-22 Angeletti P Ist Richerche Bio Uso di sostanze che attivano il recettore del cntf ( fattore neurotrofico ciliare) per la preparazione di farmaci per la terapia
EP1200589A1 (en) * 1999-08-13 2002-05-02 Regeneron Pharmaceuticals, Inc. Modified ciliary neurotrophic factor, method of making and methods of use thereof

Also Published As

Publication number Publication date
BR0207705A (pt) 2004-03-23
HUP0303310A2 (hu) 2003-12-29
WO2002070698A3 (en) 2003-11-20
JP2004529629A (ja) 2004-09-30
EP1379655A2 (en) 2004-01-14
US20040087503A1 (en) 2004-05-06
MXPA03007839A (es) 2003-12-08
CA2439682A1 (en) 2002-09-12
KR20030081480A (ko) 2003-10-17
RU2003129069A (ru) 2005-04-20
WO2002070698A2 (en) 2002-09-12
CN1494593A (zh) 2004-05-05
ZA200307678B (en) 2004-08-31

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Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)