PL3638277T3 - Kompozycje i sposoby hamowania beta sekretazy - Google Patents

Kompozycje i sposoby hamowania beta sekretazy

Info

Publication number
PL3638277T3
PL3638277T3 PL18816475.0T PL18816475T PL3638277T3 PL 3638277 T3 PL3638277 T3 PL 3638277T3 PL 18816475 T PL18816475 T PL 18816475T PL 3638277 T3 PL3638277 T3 PL 3638277T3
Authority
PL
Poland
Prior art keywords
compositions
methods
beta secretase
secretase inhibition
inhibition
Prior art date
Application number
PL18816475.0T
Other languages
English (en)
Inventor
Muhammed Majeed
Kalyanam Nagabhushanam
Original Assignee
Sami Labs Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sami Labs Limited filed Critical Sami Labs Limited
Publication of PL3638277T3 publication Critical patent/PL3638277T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/3533,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2121/00Preparations for use in therapy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Confectionery (AREA)
PL18816475.0T 2017-06-15 2018-06-14 Kompozycje i sposoby hamowania beta sekretazy PL3638277T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762520141P 2017-06-15 2017-06-15
PCT/US2018/037454 WO2018232063A1 (en) 2017-06-15 2018-06-14 Compositions and methods for beta secretase inhibition

Publications (1)

Publication Number Publication Date
PL3638277T3 true PL3638277T3 (pl) 2025-03-10

Family

ID=64655980

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18816475.0T PL3638277T3 (pl) 2017-06-15 2018-06-14 Kompozycje i sposoby hamowania beta sekretazy
PL18817403.1T PL3638278T3 (pl) 2017-06-15 2018-06-15 Kompozycje neuroprotekcyjne i ich zastosowanie

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL18817403.1T PL3638278T3 (pl) 2017-06-15 2018-06-15 Kompozycje neuroprotekcyjne i ich zastosowanie

Country Status (9)

Country Link
US (2) US11458117B2 (pl)
EP (2) EP3638277B1 (pl)
JP (2) JP7209645B2 (pl)
KR (2) KR20190134809A (pl)
CA (2) CA3063751C (pl)
ES (1) ES3005508T3 (pl)
FI (1) FI3638277T3 (pl)
PL (2) PL3638277T3 (pl)
WO (2) WO2018232063A1 (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES3005508T3 (en) * 2017-06-15 2025-03-14 Sami Labs Ltd Compositions and methods for beta secretase inhibition
US12465585B2 (en) * 2018-06-15 2025-11-11 Sami-Sabinsa Group Limited Compositions for the management of seizure induced neurotoxicity
CN110115712A (zh) * 2019-07-04 2019-08-13 兰州大学 一种同时激活氧化磷酸化通路和抑制糖酵解途径的激活剂及其应用
US11351102B2 (en) * 2019-08-26 2022-06-07 Sami-Sabinsa Group Limited Plant actives and their anti-pollution effects thereof
CN114246879B (zh) * 2021-12-30 2023-10-27 沈阳兴齐眼药股份有限公司 木蝴蝶苷b在制备用于预防、控制和/或治疗眼部疾病药物中的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8034387B2 (en) * 2002-04-30 2011-10-11 Unigen, Inc. Formulation of a mixture of free-B-ring flavonoids and flavans for use in the prevention and treatment of cognitive decline and age-related memory impairments
BRPI0309689B1 (pt) * 2002-04-30 2021-06-29 Unigen, Inc Composições compreendendo uma mistura de flavonóides de anel-b-livre e flavanos e usos das mesmas
US8945518B2 (en) * 2002-04-30 2015-02-03 Unigen, Inc. Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions
EP1660109A4 (en) * 2003-09-02 2009-04-08 Unigen Pharmaceuticals Inc FORMULATION OF A MIXTURE OF FREE B-RING FLAVONOIDS AND FLAVANES FOR USE IN THE PREVENTION AND TREATMENT OF COGNITIVE WEAKNESSING AND AGING MEMORY DISORDERS
EP1976508A2 (en) * 2006-01-09 2008-10-08 Council of Scientific and Industrial Research Flavonoids isolated from oroxylum indicum for treatment of gastrointestinal toxicity, associated symptoms and ulcers
WO2007096739A2 (en) * 2006-02-21 2007-08-30 Council Of Scientific And Industrial Research Intestinal alpha-glucosidase inhibitors and a process for the isolation and use thereof
WO2007112288A2 (en) * 2006-03-23 2007-10-04 Mount Sinai School Of Medicine Cardiovascular composition and use the same for the treatment of alzheimers disease
KR20080008929A (ko) * 2006-11-20 2008-01-24 대한민국(관리부서 식품의약품 안전청장) 오록실린 a를 함유하는 인지 기능 장애 관련 질환의 예방및 개선용 건강기능식품
AU2013308693A1 (en) * 2012-08-29 2015-03-12 Mannkind Corporation Method and composition for treating hyperglycemia
EP3538089B1 (en) * 2016-11-11 2024-12-25 Sami-Sabinsa Group Limited Composition containing oroxylin a and method of extraction thereof
ES3005508T3 (en) * 2017-06-15 2025-03-14 Sami Labs Ltd Compositions and methods for beta secretase inhibition

Also Published As

Publication number Publication date
EP3638278A4 (en) 2021-03-17
US20180360801A1 (en) 2018-12-20
KR20190131589A (ko) 2019-11-26
US11458117B2 (en) 2022-10-04
JP2020523342A (ja) 2020-08-06
FI3638277T3 (fi) 2025-01-10
JP7209645B2 (ja) 2023-01-20
ES3005508T3 (en) 2025-03-14
WO2018232063A1 (en) 2018-12-20
EP3638277B1 (en) 2024-10-09
US10894029B2 (en) 2021-01-19
CA3063751C (en) 2023-01-03
PL3638278T3 (pl) 2022-10-03
CA3063751A1 (en) 2018-12-20
JP6796217B2 (ja) 2020-12-02
JP2020523372A (ja) 2020-08-06
US20180360800A1 (en) 2018-12-20
KR20190134809A (ko) 2019-12-04
EP3638277A1 (en) 2020-04-22
CA3063757C (en) 2023-08-01
EP3638277A4 (en) 2021-03-17
CA3063757A1 (en) 2018-12-20
EP3638278B1 (en) 2022-05-11
WO2018232224A1 (en) 2018-12-20
EP3638278A1 (en) 2020-04-22

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