PL3641730T3 - Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania - Google Patents

Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania

Info

Publication number
PL3641730T3
PL3641730T3 PL18821648T PL18821648T PL3641730T3 PL 3641730 T3 PL3641730 T3 PL 3641730T3 PL 18821648 T PL18821648 T PL 18821648T PL 18821648 T PL18821648 T PL 18821648T PL 3641730 T3 PL3641730 T3 PL 3641730T3
Authority
PL
Poland
Prior art keywords
camptothecin
particle
shell
core
preparation
Prior art date
Application number
PL18821648T
Other languages
English (en)
Inventor
Young Hwan Park
Il Hyun Lee
Original Assignee
SNBioScience Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SNBioScience Inc. filed Critical SNBioScience Inc.
Publication of PL3641730T3 publication Critical patent/PL3641730T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5089Processes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/70Nanostructure
    • Y10S977/773Nanoparticle, i.e. structure having three dimensions of 100 nm or less
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S977/00Nanotechnology
    • Y10S977/902Specified use of nanostructure
    • Y10S977/904Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
    • Y10S977/906Drug delivery

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
PL18821648T 2017-06-22 2018-06-22 Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania PL3641730T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20170079354 2017-06-22
PCT/KR2018/007114 WO2018236190A1 (en) 2017-06-22 2018-06-22 Particle and pharmaceutical composition comprising an insoluble camptothecin compound with double core-shell structure and method for manufacturing the same
EP18821648.5A EP3641730B1 (en) 2017-06-22 2018-06-22 Particle and pharmaceutical composition comprising an insoluble camptothecin compound with double core-shell structure and method for manufacturing the same

Publications (1)

Publication Number Publication Date
PL3641730T3 true PL3641730T3 (pl) 2021-08-23

Family

ID=64691301

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18821648T PL3641730T3 (pl) 2017-06-22 2018-06-22 Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania

Country Status (18)

Country Link
US (6) US10980796B2 (pl)
EP (1) EP3641730B1 (pl)
JP (1) JP7027666B2 (pl)
KR (1) KR102094543B1 (pl)
CN (1) CN110769813A (pl)
AU (1) AU2018289188B2 (pl)
CA (1) CA3064564C (pl)
DK (1) DK3641730T3 (pl)
ES (1) ES2865055T3 (pl)
HR (1) HRP20210767T1 (pl)
HU (1) HUE053929T2 (pl)
IL (1) IL270818B2 (pl)
NZ (1) NZ759175A (pl)
PL (1) PL3641730T3 (pl)
PT (1) PT3641730T (pl)
RU (1) RU2745070C1 (pl)
SI (1) SI3641730T1 (pl)
WO (1) WO2018236190A1 (pl)

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* Cited by examiner, † Cited by third party
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PL3641730T3 (pl) 2017-06-22 2021-08-23 SNBioScience Inc. Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania
EP3984630A1 (en) * 2020-10-13 2022-04-20 Paris Sciences et Lettres Freeze-dried microbubbles, their use, and method for producing the same
NZ801252A (en) * 2020-11-27 2026-03-27 Snbioscience Inc Pharmaceutical composition comprising insoluble camptothecin compound-containing nanoparticle for treatment of cancer and combination therapy thereof
CN114605600B (zh) * 2022-01-18 2023-01-06 华南理工大学 一种酯酶响应的两亲性线性聚合物及其制备方法与应用
WO2024138096A2 (en) * 2022-12-22 2024-06-27 Biopurification, Llc Taxane formulations
CN117017916B (zh) * 2023-09-20 2025-09-12 天津市人民医院 一种含伊立替康的聚合物胶束、制剂及用途
CN119822681B (zh) * 2025-03-18 2025-06-17 四川宇砼建材有限公司 一种耐低温早强型无碱液体速凝剂及其制备方法

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US6407117B1 (en) * 1998-06-18 2002-06-18 The George Washington University Method of administering camptothecin compounds for the treatment of cancer with reduced side effects
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KR100773078B1 (ko) 2001-06-21 2007-11-02 주식회사 삼양사 결정성이 높은 난용성 약물을 함유하는 고분자 미셀형약물 조성물
JP4994039B2 (ja) 2003-11-26 2012-08-08 スパーナス ファーマシューティカルズ インコーポレイテッド 脂溶性または疎水性化合物の送達に有用なミセル系
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JP2012512175A (ja) * 2008-12-15 2012-05-31 バインド バイオサイエンシズ インコーポレイテッド 治療薬を徐放するための長時間循環性ナノ粒子
EP2201935B1 (en) 2008-12-26 2020-07-08 Samyang Biopharmaceuticals Corporation Polymeric micelle composition containing a poorly soluble drug and preparation method of the same
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PL3641730T3 (pl) 2017-06-22 2021-08-23 SNBioScience Inc. Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania

Also Published As

Publication number Publication date
DK3641730T3 (da) 2021-05-03
CA3064564C (en) 2021-11-30
IL270818A (en) 2020-01-30
KR20190000325A (ko) 2019-01-02
US20210228569A1 (en) 2021-07-29
PT3641730T (pt) 2021-04-01
US11793804B2 (en) 2023-10-24
BR112019024744A2 (pt) 2020-06-16
US20210228568A1 (en) 2021-07-29
JP7027666B2 (ja) 2022-03-02
AU2018289188B2 (en) 2020-12-24
RU2745070C1 (ru) 2021-03-18
CN110769813A (zh) 2020-02-07
HRP20210767T1 (hr) 2021-07-23
EP3641730B1 (en) 2021-03-03
CA3064564A1 (en) 2018-12-27
HUE053929T2 (hu) 2021-07-28
US20210236480A1 (en) 2021-08-05
US10980796B2 (en) 2021-04-20
KR102094543B1 (ko) 2020-03-27
AU2018289188A1 (en) 2019-12-05
EP3641730A1 (en) 2020-04-29
US20180369231A1 (en) 2018-12-27
NZ759175A (en) 2022-07-01
IL270818B2 (en) 2025-06-01
JP2020524712A (ja) 2020-08-20
EP3641730A4 (en) 2020-06-24
IL270818B1 (en) 2025-02-01
US20210308122A1 (en) 2021-10-07
ES2865055T3 (es) 2021-10-14
US11793803B2 (en) 2023-10-24
WO2018236190A1 (en) 2018-12-27
US20240325377A1 (en) 2024-10-03
SI3641730T1 (sl) 2021-08-31

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