PL3641730T3 - Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania - Google Patents
Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzaniaInfo
- Publication number
- PL3641730T3 PL3641730T3 PL18821648T PL18821648T PL3641730T3 PL 3641730 T3 PL3641730 T3 PL 3641730T3 PL 18821648 T PL18821648 T PL 18821648T PL 18821648 T PL18821648 T PL 18821648T PL 3641730 T3 PL3641730 T3 PL 3641730T3
- Authority
- PL
- Poland
- Prior art keywords
- camptothecin
- particle
- shell
- core
- preparation
- Prior art date
Links
- VSJKWCGYPAHWDS-FQEVSTJZSA-N camptothecin Chemical class C1=CC=C2C=C(CN3C4=CC5=C(C3=O)COC(=O)[C@]5(O)CC)C4=NC2=C1 VSJKWCGYPAHWDS-FQEVSTJZSA-N 0.000 title 1
- 230000009977 dual effect Effects 0.000 title 1
- 239000002245 particle Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poly(lactide-co-glycolide)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5089—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/70—Nanostructure
- Y10S977/773—Nanoparticle, i.e. structure having three dimensions of 100 nm or less
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20170079354 | 2017-06-22 | ||
| EP18821648.5A EP3641730B1 (en) | 2017-06-22 | 2018-06-22 | Particle and pharmaceutical composition comprising an insoluble camptothecin compound with double core-shell structure and method for manufacturing the same |
| PCT/KR2018/007114 WO2018236190A1 (en) | 2017-06-22 | 2018-06-22 | Particle and pharmaceutical composition comprising an insoluble camptothecin compound with double core-shell structure and method for manufacturing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3641730T3 true PL3641730T3 (pl) | 2021-08-23 |
Family
ID=64691301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18821648T PL3641730T3 (pl) | 2017-06-22 | 2018-06-22 | Cząstka i kompozycja farmaceutyczna zawierająca nierozpuszczalną pochodną kamptotecyny z podwójną strukturą rdzenia i powłoki oraz sposób ich wytwarzania |
Country Status (18)
| Country | Link |
|---|---|
| US (6) | US10980796B2 (pl) |
| EP (1) | EP3641730B1 (pl) |
| JP (1) | JP7027666B2 (pl) |
| KR (1) | KR102094543B1 (pl) |
| CN (1) | CN110769813A (pl) |
| AU (1) | AU2018289188B2 (pl) |
| CA (1) | CA3064564C (pl) |
| DK (1) | DK3641730T3 (pl) |
| ES (1) | ES2865055T3 (pl) |
| HR (1) | HRP20210767T1 (pl) |
| HU (1) | HUE053929T2 (pl) |
| IL (1) | IL270818B2 (pl) |
| NZ (1) | NZ759175A (pl) |
| PL (1) | PL3641730T3 (pl) |
| PT (1) | PT3641730T (pl) |
| RU (1) | RU2745070C1 (pl) |
| SI (1) | SI3641730T1 (pl) |
| WO (1) | WO2018236190A1 (pl) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL270818B2 (en) * | 2017-06-22 | 2025-06-01 | Snbioscience Inc | Particle and pharmaceutical composition comprising an insoluble camptothecin compound with double core-shell structure and method for manufacturing the same |
| EP3984630A1 (en) * | 2020-10-13 | 2022-04-20 | Paris Sciences et Lettres | Freeze-dried microbubbles, their use, and method for producing the same |
| IL303103A (en) | 2020-11-27 | 2023-07-01 | Snbioscience Inc | A pharmaceutical composition that includes insoluble nanoparticles containing a camptothecin compound for the treatment of cancer and its combined treatment |
| CN114605600B (zh) * | 2022-01-18 | 2023-01-06 | 华南理工大学 | 一种酯酶响应的两亲性线性聚合物及其制备方法与应用 |
| WO2024138096A2 (en) * | 2022-12-22 | 2024-06-27 | Biopurification, Llc | Taxane formulations |
| CN117017916B (zh) * | 2023-09-20 | 2025-09-12 | 天津市人民医院 | 一种含伊立替康的聚合物胶束、制剂及用途 |
| CN119822681B (zh) * | 2025-03-18 | 2025-06-17 | 四川宇砼建材有限公司 | 一种耐低温早强型无碱液体速凝剂及其制备方法 |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100289074B1 (ko) * | 1998-02-04 | 2001-07-12 | 김윤 | 난용성약물함유시스템 |
| US6407117B1 (en) * | 1998-06-18 | 2002-06-18 | The George Washington University | Method of administering camptothecin compounds for the treatment of cancer with reduced side effects |
| US7217770B2 (en) | 2000-05-17 | 2007-05-15 | Samyang Corporation | Stable polymeric micelle-type drug composition and method for the preparation thereof |
| KR100773078B1 (ko) | 2001-06-21 | 2007-11-02 | 주식회사 삼양사 | 결정성이 높은 난용성 약물을 함유하는 고분자 미셀형약물 조성물 |
| JP4994039B2 (ja) | 2003-11-26 | 2012-08-08 | スパーナス ファーマシューティカルズ インコーポレイテッド | 脂溶性または疎水性化合物の送達に有用なミセル系 |
| CN101106995B (zh) | 2004-11-05 | 2011-10-19 | 株式会社三养社 | 在非水极性溶剂中增加溶解度的10-羟基喜树碱类化合物的药物制剂 |
| US20140314864A1 (en) * | 2006-03-31 | 2014-10-23 | Massachusetts Institute Of Technology | System for Targeted Delivery of Therapeutic Agents |
| DK2644192T3 (en) * | 2007-09-28 | 2017-06-26 | Pfizer | Cancer cell targeting using nanoparticles |
| CN101199857B (zh) * | 2007-12-12 | 2011-04-13 | 中国药科大学 | mPEG-PLA-喜树碱类药物的结合物 |
| EA021422B1 (ru) * | 2008-06-16 | 2015-06-30 | Бинд Терапьютикс, Инк. | Полимерные наночастицы, содержащие терапевтическое средство, и способ их получения |
| EP2379064B1 (en) * | 2008-12-15 | 2020-02-26 | Pfizer Inc. | Long circulating nanoparticles for sustained release of therapeutic agents |
| EP2201935B1 (en) * | 2008-12-26 | 2020-07-08 | Samyang Biopharmaceuticals Corporation | Polymeric micelle composition containing a poorly soluble drug and preparation method of the same |
| US20100203150A1 (en) * | 2009-02-06 | 2010-08-12 | National Tsing Hua University | Novel amphiphilic copolymers and fabrication method thereof |
| US8299178B2 (en) * | 2009-03-25 | 2012-10-30 | National Tsing Hua University | Stable micelles formed with diblock copolymers of critical micelle concentration copolymer and temperature-sensitive copolymer |
| CN101869712B (zh) | 2009-04-21 | 2016-01-20 | 财团法人工业技术研究院 | 使用包囊抗肿瘤药物的聚合胶束用于治疗肿瘤的药物组合物 |
| CN101628919B (zh) * | 2009-08-20 | 2011-11-23 | 浙江大学 | 喜树碱及其衍生物的自乳化药物前体及其应用 |
| CA3037168A1 (en) | 2009-12-18 | 2011-06-23 | Interface Biologics, Inc. | Local delivery of drugs from self assembled coatings |
| JP5971769B2 (ja) | 2011-03-15 | 2016-08-17 | ザ ユニバーシティー オブ ノースカロライナ アット チャペル ヒル | アントラサイクリン療法を用いて乳癌を処置する方法 |
| CN102746314B (zh) | 2011-04-18 | 2016-07-06 | 华东师范大学 | 含有稳定7元内酯环的喜树碱类化合物、制备方法和用途 |
| WO2014059022A1 (en) * | 2012-10-09 | 2014-04-17 | The Brigham And Women's Hospital, Inc. | Nanoparticles for targeted delivery of multiple therapeutic agents and methods of use |
| CN102961332A (zh) * | 2012-12-05 | 2013-03-13 | 复旦大学 | 提高喜树碱类衍生物活性闭环率的液体胶束制剂及其制备方法和应用 |
| CN103638027B (zh) * | 2013-11-08 | 2016-03-09 | 浙江大学 | 利用双亲性药物包载疏水性抗肿瘤药物的方法及制剂 |
| GB201412841D0 (en) | 2014-07-18 | 2014-09-03 | Univ Liverpool | Particles |
| KR102498088B1 (ko) | 2015-12-30 | 2023-02-09 | 코웨이 주식회사 | 폐수의 재활용이 가능한 이동식 헤어 클리닝 시스템 |
| IL270818B2 (en) | 2017-06-22 | 2025-06-01 | Snbioscience Inc | Particle and pharmaceutical composition comprising an insoluble camptothecin compound with double core-shell structure and method for manufacturing the same |
-
2018
- 2018-06-22 IL IL270818A patent/IL270818B2/en unknown
- 2018-06-22 WO PCT/KR2018/007114 patent/WO2018236190A1/en not_active Ceased
- 2018-06-22 NZ NZ759175A patent/NZ759175A/en unknown
- 2018-06-22 ES ES18821648T patent/ES2865055T3/es active Active
- 2018-06-22 KR KR1020180072357A patent/KR102094543B1/ko active Active
- 2018-06-22 PT PT188216485T patent/PT3641730T/pt unknown
- 2018-06-22 PL PL18821648T patent/PL3641730T3/pl unknown
- 2018-06-22 CA CA3064564A patent/CA3064564C/en active Active
- 2018-06-22 US US16/015,470 patent/US10980796B2/en active Active
- 2018-06-22 JP JP2020520413A patent/JP7027666B2/ja active Active
- 2018-06-22 CN CN201880041446.5A patent/CN110769813A/zh active Pending
- 2018-06-22 AU AU2018289188A patent/AU2018289188B2/en active Active
- 2018-06-22 HR HRP20210767TT patent/HRP20210767T1/hr unknown
- 2018-06-22 DK DK18821648.5T patent/DK3641730T3/da active
- 2018-06-22 HU HUE18821648A patent/HUE053929T2/hu unknown
- 2018-06-22 RU RU2019136373A patent/RU2745070C1/ru active
- 2018-06-22 SI SI201830281T patent/SI3641730T1/sl unknown
- 2018-06-22 EP EP18821648.5A patent/EP3641730B1/en active Active
-
2021
- 2021-04-16 US US17/233,040 patent/US11793803B2/en active Active
- 2021-04-16 US US17/233,069 patent/US11793804B2/en active Active
- 2021-04-16 US US17/233,091 patent/US20210228569A1/en not_active Abandoned
- 2021-04-16 US US17/233,153 patent/US20210308122A1/en not_active Abandoned
-
2023
- 2023-10-06 US US18/377,679 patent/US20240325377A1/en not_active Abandoned
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