PL3645513T3 - Pochodne benzoazepiny - Google Patents
Pochodne benzoazepinyInfo
- Publication number
- PL3645513T3 PL3645513T3 PL18743103.6T PL18743103T PL3645513T3 PL 3645513 T3 PL3645513 T3 PL 3645513T3 PL 18743103 T PL18743103 T PL 18743103T PL 3645513 T3 PL3645513 T3 PL 3645513T3
- Authority
- PL
- Poland
- Prior art keywords
- benzoazepine derivatives
- benzoazepine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Vascular Medicine (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Gastroenterology & Hepatology (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/JP2017/024211 WO2019003433A1 (ja) | 2017-06-30 | 2017-06-30 | ベンゾアゼピン誘導体 |
| PCT/JP2018/024786 WO2019004421A1 (en) | 2017-06-30 | 2018-06-29 | BENZAZEPINE DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3645513T3 true PL3645513T3 (pl) | 2022-12-19 |
Family
ID=62976113
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18743103.6T PL3645513T3 (pl) | 2017-06-30 | 2018-06-29 | Pochodne benzoazepiny |
| PL22164702.7T PL4056557T3 (pl) | 2017-06-30 | 2018-06-29 | Pochodne benzoazepiny użyteczne jako leki |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL22164702.7T PL4056557T3 (pl) | 2017-06-30 | 2018-06-29 | Pochodne benzoazepiny użyteczne jako leki |
Country Status (23)
| Country | Link |
|---|---|
| US (4) | US10889570B2 (pl) |
| EP (2) | EP4056557B1 (pl) |
| JP (2) | JP6688436B2 (pl) |
| KR (1) | KR102632228B1 (pl) |
| CN (2) | CN110891939A (pl) |
| AU (1) | AU2018293081B2 (pl) |
| CA (1) | CA3068396A1 (pl) |
| DK (2) | DK4056557T3 (pl) |
| EA (1) | EA202090131A1 (pl) |
| ES (2) | ES2932854T3 (pl) |
| FI (1) | FI4056557T3 (pl) |
| HR (2) | HRP20221359T1 (pl) |
| HU (2) | HUE060855T2 (pl) |
| IL (1) | IL271665B2 (pl) |
| LT (2) | LT4056557T (pl) |
| PH (1) | PH12020500034A1 (pl) |
| PL (2) | PL3645513T3 (pl) |
| PT (2) | PT4056557T (pl) |
| SA (1) | SA519410888B1 (pl) |
| SG (1) | SG11201912757VA (pl) |
| SI (1) | SI4056557T1 (pl) |
| TW (1) | TWI798234B (pl) |
| WO (2) | WO2019003433A1 (pl) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6868089B2 (ja) * | 2018-12-28 | 2021-05-12 | 大塚製薬株式会社 | 医薬 |
| CA3160645A1 (en) | 2019-11-07 | 2021-05-14 | The Board Of Trustees Of The University Of Illinois | Inhibitors of influenza viral entry |
| CN111450879A (zh) * | 2020-05-08 | 2020-07-28 | 内蒙古自治区石油化工监督检验研究院 | 用于乙炔氢氯化反应的丙二胺改性低钌催化剂及制备方法 |
| JP7627343B2 (ja) * | 2020-11-26 | 2025-02-05 | シャンハイ ジェミンケア ファーマシューティカル カンパニー，リミティド | 新規ベンズアゼピンスピロ環式誘導体 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2089033T3 (es) | 1989-10-20 | 1996-10-01 | Otsuka Pharma Co Ltd | Compuestos benzoheterociclicos. |
| US5258510A (en) * | 1989-10-20 | 1993-11-02 | Otsuka Pharma Co Ltd | Benzoheterocyclic compounds |
| JP2905909B2 (ja) | 1991-04-19 | 1999-06-14 | 大塚製薬株式会社 | バソプレシン拮抗剤 |
| US5985869A (en) * | 1989-10-20 | 1999-11-16 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds |
| WO1994001113A1 (en) | 1992-07-02 | 1994-01-20 | Otsuka Pharmaceutical Company, Limited | Oxytocin antagonist |
| WO1994004525A1 (en) | 1992-08-20 | 1994-03-03 | Otsuka Pharmaceutical Company, Limited | Benzoheterocyclic compounds as oxytocin and vasopressin antagonists |
| JP2961291B2 (ja) * | 1992-08-20 | 1999-10-12 | 大塚製薬株式会社 | ベンゾヘテロ環化合物 |
| JP2913082B2 (ja) * | 1992-10-16 | 1999-06-28 | 大塚製薬株式会社 | バソプレシン拮抗剤及びオキシトシン拮抗剤 |
| TW270927B (pl) | 1992-10-16 | 1996-02-21 | Otsuka Pharma Co Ltd | |
| FI960867A0 (fi) * | 1993-08-26 | 1996-02-26 | Yamanouchi Pharma Co Ltd | Bentsatsepiinijohdannainen, sen farmaseuttinen seos ja välituote |
| ATE360617T1 (de) | 1994-06-15 | 2007-05-15 | Otsuka Pharma Co Ltd | Benzoheterocyclische verbindungen verwendbar als vasopressin- oder oxytocin-modulatoren |
| JPH09221476A (ja) | 1995-12-15 | 1997-08-26 | Otsuka Pharmaceut Co Ltd | 医薬組成物 |
| JPH10120592A (ja) | 1996-10-22 | 1998-05-12 | Otsuka Pharmaceut Co Ltd | メニエール病乃至メニエール症候群治療剤 |
| AUPP150098A0 (en) * | 1998-01-27 | 1998-02-19 | Fujisawa Pharmaceutical Co., Ltd. | Benzamide derivatives |
| JP4374088B2 (ja) * | 1999-01-14 | 2009-12-02 | 東ソ−・エフテック株式会社 | 新規な４，４−ジフルオロベンゾアゼピンケタール誘導体、およびそれを経由する４，４−ジフルオロベンゾアゼピン−５−オン誘導体の製造方法 |
| EP1627876A1 (en) * | 2004-08-20 | 2006-02-22 | Ferring B.V. | Heterocyclic condensed compounds useful as antidiuretic agents |
| TWI459947B (zh) * | 2007-06-26 | 2014-11-11 | Otsuka Pharma Co Ltd | 苯并氮呯化合物及藥學製劑 |
| CN102753530B (zh) * | 2009-10-26 | 2015-06-17 | 大塚制药株式会社 | 苯并氮杂*化合物 |
| US8025813B2 (en) | 2009-11-12 | 2011-09-27 | Rohm And Haas Electronic Materials Cmp Holdings, Inc. | Chemical mechanical polishing composition and methods relating thereto |
| JP2016513112A (ja) * | 2013-02-18 | 2016-05-12 | ザ スクリプス リサーチ インスティテュート | 治療的潜在能力を有するバソプレッシン受容体のモジュレーター |
| TW201605488A (zh) | 2013-10-15 | 2016-02-16 | 大塚製藥股份有限公司 | 用以預防及／或治療多囊腎病之藥物 |
-
2017
- 2017-06-30 WO PCT/JP2017/024211 patent/WO2019003433A1/ja not_active Ceased
-
2018
- 2018-06-29 SI SI201831037T patent/SI4056557T1/sl unknown
- 2018-06-29 KR KR1020207002409A patent/KR102632228B1/ko active Active
- 2018-06-29 EA EA202090131A patent/EA202090131A1/ru unknown
- 2018-06-29 EP EP22164702.7A patent/EP4056557B1/en active Active
- 2018-06-29 EP EP18743103.6A patent/EP3645513B1/en active Active
- 2018-06-29 WO PCT/JP2018/024786 patent/WO2019004421A1/en not_active Ceased
- 2018-06-29 ES ES18743103T patent/ES2932854T3/es active Active
- 2018-06-29 CN CN201880041463.9A patent/CN110891939A/zh active Pending
- 2018-06-29 HU HUE18743103A patent/HUE060855T2/hu unknown
- 2018-06-29 HR HRP20221359TT patent/HRP20221359T1/hr unknown
- 2018-06-29 PT PT221647027T patent/PT4056557T/pt unknown
- 2018-06-29 TW TW107122567A patent/TWI798234B/zh active
- 2018-06-29 HR HRP20231616TT patent/HRP20231616T1/hr unknown
- 2018-06-29 ES ES22164702T patent/ES2964569T3/es active Active
- 2018-06-29 CN CN202510106289.3A patent/CN120025312A/zh active Pending
- 2018-06-29 US US16/480,842 patent/US10889570B2/en active Active
- 2018-06-29 PL PL18743103.6T patent/PL3645513T3/pl unknown
- 2018-06-29 HU HUE22164702A patent/HUE065010T2/hu unknown
- 2018-06-29 JP JP2019536110A patent/JP6688436B2/ja active Active
- 2018-06-29 FI FIEP22164702.7T patent/FI4056557T3/fi active
- 2018-06-29 AU AU2018293081A patent/AU2018293081B2/en active Active
- 2018-06-29 DK DK22164702.7T patent/DK4056557T3/da active
- 2018-06-29 DK DK18743103.6T patent/DK3645513T3/da active
- 2018-06-29 PL PL22164702.7T patent/PL4056557T3/pl unknown
- 2018-06-29 PT PT187431036T patent/PT3645513T/pt unknown
- 2018-06-29 LT LTEP22164702.7T patent/LT4056557T/lt unknown
- 2018-06-29 SG SG11201912757VA patent/SG11201912757VA/en unknown
- 2018-06-29 CA CA3068396A patent/CA3068396A1/en active Pending
- 2018-06-29 LT LTEPPCT/JP2018/024786T patent/LT3645513T/lt unknown
-
2019
- 2019-12-23 IL IL271665A patent/IL271665B2/en unknown
- 2019-12-24 SA SA519410888A patent/SA519410888B1/ar unknown
-
2020
- 2020-01-02 PH PH12020500034A patent/PH12020500034A1/en unknown
- 2020-04-03 JP JP2020067672A patent/JP7055160B2/ja active Active
- 2020-11-24 US US17/103,319 patent/US11673878B2/en active Active
-
2023
- 2023-04-27 US US18/140,348 patent/US20230265073A1/en not_active Abandoned
-
2024
- 2024-10-25 US US18/927,326 patent/US20250051310A1/en active Pending
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