PL3658122T3 - Kompozycja farmaceutyczna zawierająca sakubitryl i walsartan - Google Patents

Kompozycja farmaceutyczna zawierająca sakubitryl i walsartan

Info

Publication number
PL3658122T3
PL3658122T3 PL18759256T PL18759256T PL3658122T3 PL 3658122 T3 PL3658122 T3 PL 3658122T3 PL 18759256 T PL18759256 T PL 18759256T PL 18759256 T PL18759256 T PL 18759256T PL 3658122 T3 PL3658122 T3 PL 3658122T3
Authority
PL
Poland
Prior art keywords
sacubitril
valsartan
pharmaceutical composition
pharmaceutical
composition
Prior art date
Application number
PL18759256T
Other languages
English (en)
Inventor
Bohumil Dymacek
Marta VIVANCOS MARTINEZ
Luis Nogueiras Nieto
Lisardo ÁLVAREZ FERNÁNDEZ
Rohit Kumar
Jose VELADA CALZADA
Petr MITAS
Original Assignee
Synthon B.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthon B.V. filed Critical Synthon B.V.
Publication of PL3658122T3 publication Critical patent/PL3658122T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/225—Polycarboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL18759256T 2017-07-28 2018-07-25 Kompozycja farmaceutyczna zawierająca sakubitryl i walsartan PL3658122T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17183859 2017-07-28
EP18759256.3A EP3658122B1 (en) 2017-07-28 2018-07-25 Pharmaceutical composition comprising sacubitril and valsartan
PCT/EP2018/070212 WO2019020706A1 (en) 2017-07-28 2018-07-25 PHARMACEUTICAL COMPOSITION COMPRISING SACUBITRIL AND VALSARTAN

Publications (1)

Publication Number Publication Date
PL3658122T3 true PL3658122T3 (pl) 2021-10-18

Family

ID=59501295

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18759256T PL3658122T3 (pl) 2017-07-28 2018-07-25 Kompozycja farmaceutyczna zawierająca sakubitryl i walsartan

Country Status (7)

Country Link
US (1) US10588892B2 (pl)
EP (1) EP3658122B1 (pl)
EA (1) EA202090398A1 (pl)
ES (1) ES2881317T3 (pl)
MX (1) MX391562B (pl)
PL (1) PL3658122T3 (pl)
WO (1) WO2019020706A1 (pl)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3508479A4 (en) * 2016-09-02 2020-02-19 Noratech Pharmaceuticals, Inc. CRYSTALLINE FORMS OF VALSARTAN DISODIUM SALT
EP4088715A1 (en) 2021-05-14 2022-11-16 KRKA, d.d., Novo mesto Pharmaceutical formulation of valsartan and sacubitril
TR2022006846A1 (tr) * 2022-04-26 2023-11-21 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Kuru granülasyon yöntemi̇yle hazirlanan sakubi̇tri̇l ve valsartan i̇çeren bi̇r tablet
EP4268806A3 (en) * 2022-04-26 2023-12-27 Sanovel Ilac Sanayi Ve Ticaret A.S. A tablet comprising sacubitril and valsartan processed with dry granulation

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0443983B1 (de) 1990-02-19 1996-02-28 Ciba-Geigy Ag Acylverbindungen
EP0498361A3 (en) 1991-02-06 1992-09-02 Schering Corporation Combination of an angiotensin ii antagonist or renin inhibitor with a neutral endopeptidase inhibitor
US5217996A (en) 1992-01-22 1993-06-08 Ciba-Geigy Corporation Biaryl substituted 4-amino-butyric acid amides
CA2168066A1 (en) 1995-02-08 1996-08-09 James R. Powell Treatment of hypertension and congestive heart failure
US6204281B1 (en) 1998-07-10 2001-03-20 Novartis Ag Method of treatment and pharmaceutical composition
CZ303389B6 (cs) 2000-07-19 2012-08-29 Novartis Ag Sul valsartanu a farmaceutický prípravek obsahující tuto sul
DE60315795T2 (de) 2002-01-17 2008-06-05 Novartis Ag Pharmazeutische zusammensetzung enthaltend valsartan und nep-inhibitoren
US7468390B2 (en) 2002-01-17 2008-12-23 Novartis Ag Methods of treatment and pharmaceutical composition
AR057882A1 (es) 2005-11-09 2007-12-26 Novartis Ag Compuestos de accion doble de bloqueadores del receptor de angiotensina e inhibidores de endopeptidasa neutra
KR101589317B1 (ko) 2007-11-06 2016-01-28 노파르티스 아게 안지오텐신 수용체 길항제/차단제 (arb) 및 중성 엔도펩티다제 (nep) 억제제의 초구조에 기초한 이중-작용 제약 조성물
WO2013181455A1 (en) * 2012-05-30 2013-12-05 Robert Gellibolian Water bottle with flow meter
CN105837464A (zh) 2015-01-15 2016-08-10 四川海思科制药有限公司 沙库比曲钠的晶型及其制备方法和用途
EP3828175A1 (en) * 2015-06-12 2021-06-02 Teva Pharmaceuticals International GmbH Solid state forms of trisodium valsartan: sacubitril
WO2017012600A1 (en) 2015-07-20 2017-01-26 Zentiva, K.S. A pharmaceutical composition containing valsartan and sacubitril and methods for preparation and stabilization thereof
MX2018007129A (es) * 2015-12-11 2018-11-09 Zentiva Ks Formas solidas de ester etilico del acido (2r,4s)-5-(bifenil-4-il) -4-[(3-carboxipropionil)amino]-2-metil-pentanoico, sus sales y un metodo de preparacion.
US10722471B2 (en) * 2016-02-03 2020-07-28 Novartis Ag Galenic formulations of organic compounds

Also Published As

Publication number Publication date
ES2881317T3 (es) 2021-11-29
US10588892B2 (en) 2020-03-17
WO2019020706A1 (en) 2019-01-31
EA202090398A1 (ru) 2020-05-15
MX391562B (es) 2025-03-21
EP3658122B1 (en) 2021-04-07
EP3658122A1 (en) 2020-06-03
US20190030000A1 (en) 2019-01-31

Similar Documents

Publication Publication Date Title
ZA201802125B (en) Pharmaceutical composition and application thereof
IL269061A (en) A pharmaceutical preparation containing Selexifag
PT3603620T (pt) Composição lipossomal e composição farmacêutica
IL254552A0 (en) Polycyclic carbamoylpyridone compounds and their pharmaceutical uses
IL271986A (en) pharmaceutical preparation
EP3307265A4 (en) Pharmaceutical combination and uses thereof
IL273339A (en) Griseofulbin compound and its medical use
GB201712159D0 (en) Pharmaceutical composition
PL3583943T3 (pl) Kompozycja farmaceutyczna
IL272419A (en) Pharmaceutical composition
GB201719447D0 (en) Pharmaceutical composition
PL3646867T3 (pl) Kompozycja farmaceutyczna
PL3302483T3 (pl) Kompozycje farmaceutyczne i ich zastosowanie
IL257621B (en) A catechol derivative and a pharmaceutical preparation that includes it
ZA202000959B (en) Adamantylmethylamine derivative and use thereof as pharmaceutical
GB201519644D0 (en) Therapy and pharmaceutical composition
ZA201903341B (en) Pharmaceutical compositions and uses thereof
GB201713920D0 (en) Pharmaceutical compositions and uses thereof
AU2015901459A0 (en) Pharmaceutical powder composition and use
GB201708328D0 (en) Pharmaceutical composition
GB201708329D0 (en) Pharmaceutical composition
GB201604810D0 (en) Pharmaceutical compositions and uses
GB201705661D0 (en) Pharmaceutical composition
GB201716745D0 (en) New formulations and uses thereof
AU2015902260A0 (en) Pharmaceutical Combination and Uses Thereof