PL3658132T3 - Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related diseases - Google Patents

Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related diseases

Info

Publication number
PL3658132T3
PL3658132T3 PL18753465.6T PL18753465T PL3658132T3 PL 3658132 T3 PL3658132 T3 PL 3658132T3 PL 18753465 T PL18753465 T PL 18753465T PL 3658132 T3 PL3658132 T3 PL 3658132T3
Authority
PL
Poland
Prior art keywords
compositions
treatment
amino acids
related diseases
mitochondrial dysfunction
Prior art date
Application number
PL18753465.6T
Other languages
Polish (pl)
Inventor
Paolo Luca Maria Giorgetti
Original Assignee
Professional Dietetics S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Professional Dietetics S.P.A. filed Critical Professional Dietetics S.P.A.
Publication of PL3658132T3 publication Critical patent/PL3658132T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/194Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404Indoles, e.g. pindolol
    • A61K31/405Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A61K31/51Thiamines, e.g. vitamin B1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
PL18753465.6T 2017-07-28 2018-07-20 Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related diseases PL3658132T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT102017000087359A IT201700087359A1 (en) 2017-07-28 2017-07-28 COMPOSITIONS INCLUDING AMINO ACIDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION
PCT/IB2018/055425 WO2019021135A1 (en) 2017-07-28 2018-07-20 Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related diseases

Publications (1)

Publication Number Publication Date
PL3658132T3 true PL3658132T3 (en) 2022-08-01

Family

ID=60628070

Family Applications (2)

Application Number Title Priority Date Filing Date
PL18753465.6T PL3658132T3 (en) 2017-07-28 2018-07-20 Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related diseases
PL21174744.9T PL3915553T3 (en) 2017-07-28 2018-07-20 Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related neurodegenerative diseases

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL21174744.9T PL3915553T3 (en) 2017-07-28 2018-07-20 Compositions comprising amino acids for use in the treatment of mitochondrial dysfunction-related neurodegenerative diseases

Country Status (22)

Country Link
US (2) US11337946B2 (en)
EP (2) EP3658132B1 (en)
JP (2) JP7266767B2 (en)
KR (3) KR20240063205A (en)
CN (1) CN110996935A (en)
AU (2) AU2018306540B2 (en)
BR (1) BR112020001471A2 (en)
CA (1) CA3070197C (en)
CL (1) CL2020000220A1 (en)
DK (2) DK3658132T3 (en)
ES (2) ES3031608T3 (en)
HU (1) HUE059050T2 (en)
IT (1) IT201700087359A1 (en)
LT (1) LT3658132T (en)
MX (2) MX395240B (en)
MY (1) MY200975A (en)
PH (1) PH12020500190A1 (en)
PL (2) PL3658132T3 (en)
PT (2) PT3915553T (en)
RS (1) RS63422B1 (en)
SG (1) SG11201912103TA (en)
WO (1) WO2019021135A1 (en)

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IT201700087376A1 (en) 2017-07-28 2019-01-28 Professional Dietetics Spa COMPOSITIONS INCLUDING AMINO ACIDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION
IT201700087359A1 (en) * 2017-07-28 2019-01-28 Professional Dietetics Spa COMPOSITIONS INCLUDING AMINO ACIDS FOR USE IN THE TREATMENT OF DISEASES ASSOCIATED WITH MITOCHONDRIAL DYSFUNCTION
IT201800006725A1 (en) 2018-06-27 2019-12-27 COMPOSITIONS INCLUDING AMINO ACIDS FOR USE IN THE PREVENTION AND TREATMENT OF LIVER DISEASES
IT201900002109A1 (en) * 2019-02-13 2020-08-13 Professional Dietetics Spa COMPOSITIONS INCLUDING AMINO ACIDS FOR USE IN THE TREATMENT OF INJURIES OF THE CENTRAL NERVOUS SYSTEM
JP2021038147A (en) * 2019-08-30 2021-03-11 国立大学法人 鹿児島大学 Mitochondrial biosynthesis promoter
IT202000000454A1 (en) * 2020-01-13 2021-07-13 Professional Dietetics Spa COMPOSITIONS INCLUDING AMINO ACIDS FOR THE PREVENTION AND TREATMENT OF CANCER
IT202000000442A1 (en) 2020-01-13 2021-07-13 Professional Dietetics Spa COMPOSITIONS INCLUDING AMINO ACIDS FOR USE IN THE PREVENTION AND TREATMENT OF SIDE EFFECTS OF CHEMOTHERAPY
WO2021198400A1 (en) * 2020-04-01 2021-10-07 Société des Produits Nestlé S.A. Compositions containing amino acids and methods of using such compositions for treating sarcopenia
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TW202308604A (en) * 2021-05-10 2023-03-01 國立大學法人東北大學 Composition for increasing muscle mass
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CN120661636A (en) * 2025-06-12 2025-09-19 中国医学科学院医学实验动物研究所 Gene delivery system for expressing PPM1K specifically and preparation method and application thereof

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Also Published As

Publication number Publication date
NZ761073A (en) 2025-02-28
ES2923126T3 (en) 2022-09-23
CA3070197C (en) 2025-07-08
PT3658132T (en) 2022-07-08
US20220249418A1 (en) 2022-08-11
KR20230117642A (en) 2023-08-08
MY200975A (en) 2024-01-27
PL3915553T3 (en) 2025-08-04
PH12020500190A1 (en) 2020-09-28
LT3658132T (en) 2022-07-25
RU2019141152A (en) 2021-08-30
US11957651B2 (en) 2024-04-16
AU2023266256B2 (en) 2025-01-23
JP7513311B2 (en) 2024-07-09
DK3658132T3 (en) 2022-07-04
CA3070197A1 (en) 2019-01-31
ES3031608T3 (en) 2025-07-09
EP3915553B1 (en) 2025-03-26
HUE059050T2 (en) 2022-10-28
WO2019021135A1 (en) 2019-01-31
BR112020001471A2 (en) 2020-09-15
MX395240B (en) 2025-03-25
CN110996935A (en) 2020-04-10
JP2020528400A (en) 2020-09-24
US11337946B2 (en) 2022-05-24
EP3658132A1 (en) 2020-06-03
KR20240063205A (en) 2024-05-09
AU2018306540B2 (en) 2023-11-30
KR20200033872A (en) 2020-03-30
RU2770660C2 (en) 2022-04-20
JP2023071939A (en) 2023-05-23
EP3915553A1 (en) 2021-12-01
SG11201912103TA (en) 2020-01-30
DK3915553T3 (en) 2025-06-23
MX2020001083A (en) 2022-08-31
RU2019141152A3 (en) 2021-09-10
JP7266767B2 (en) 2023-05-01
AU2023266256A1 (en) 2023-12-07
AU2018306540A1 (en) 2020-02-20
CL2020000220A1 (en) 2020-07-31
PT3915553T (en) 2025-06-23
RS63422B1 (en) 2022-08-31
EP3658132B1 (en) 2022-04-13
US20200230093A1 (en) 2020-07-23
IT201700087359A1 (en) 2019-01-28
MX2022010774A (en) 2023-02-23
KR102566297B1 (en) 2023-08-10

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