PL366690A1 - Nowe pochodne 4,5,6,7-tetrabromobenzimidazolu oraz sposób ich otrzymywania - Google Patents
Nowe pochodne 4,5,6,7-tetrabromobenzimidazolu oraz sposób ich otrzymywaniaInfo
- Publication number
- PL366690A1 PL366690A1 PL04366690A PL36669004A PL366690A1 PL 366690 A1 PL366690 A1 PL 366690A1 PL 04366690 A PL04366690 A PL 04366690A PL 36669004 A PL36669004 A PL 36669004A PL 366690 A1 PL366690 A1 PL 366690A1
- Authority
- PL
- Poland
- Prior art keywords
- tetrabromobenzimidazole
- obtaining
- new derivatives
- derivatives
- new
- Prior art date
Links
- LOEIRDBRYBHAJB-UHFFFAOYSA-N 4,5,6,7-tetrabromo-1h-benzimidazole Chemical class BrC1=C(Br)C(Br)=C2NC=NC2=C1Br LOEIRDBRYBHAJB-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/30—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL04366690A PL366690A1 (pl) | 2004-03-29 | 2004-03-29 | Nowe pochodne 4,5,6,7-tetrabromobenzimidazolu oraz sposób ich otrzymywania |
| EP05731805A EP1778647A1 (en) | 2004-03-29 | 2005-03-29 | New derivatives of 4, 5, 6, 7-tetrabromobenzimidazole and method of their preparation |
| PCT/PL2005/000022 WO2005092866A1 (en) | 2004-03-29 | 2005-03-29 | New derivatives of 4, 5, 6, 7-tetrabromobenzimidazole and method of their preparation |
| US10/599,499 US7528259B2 (en) | 2004-03-29 | 2005-03-29 | Derivatives of 4,5,6,7-tetrabromobenzimidazole and method of their preparation |
| US12/429,359 US20090239921A1 (en) | 2004-03-29 | 2009-04-24 | Methods for treating neoplasms with derivatives of 4,5,6,7-tetrabromobenzimidazole |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL04366690A PL366690A1 (pl) | 2004-03-29 | 2004-03-29 | Nowe pochodne 4,5,6,7-tetrabromobenzimidazolu oraz sposób ich otrzymywania |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL366690A1 true PL366690A1 (pl) | 2005-10-03 |
Family
ID=34965036
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04366690A PL366690A1 (pl) | 2004-03-29 | 2004-03-29 | Nowe pochodne 4,5,6,7-tetrabromobenzimidazolu oraz sposób ich otrzymywania |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US7528259B2 (pl) |
| EP (1) | EP1778647A1 (pl) |
| PL (1) | PL366690A1 (pl) |
| WO (1) | WO2005092866A1 (pl) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20090239921A1 (en) * | 2004-03-29 | 2009-09-24 | Selvita Sp. Z.O.O. | Methods for treating neoplasms with derivatives of 4,5,6,7-tetrabromobenzimidazole |
| WO2009032213A1 (en) * | 2007-08-30 | 2009-03-12 | Cleveland State University | Control of malignant cells by kinase inhibition |
| KR20100010894A (ko) * | 2008-07-23 | 2010-02-02 | 가부시키가이샤 키노파마 | Dyrk를 저해하는 화합물을 함유하는 의약 조성물 |
| WO2010096751A1 (en) * | 2009-02-23 | 2010-08-26 | The Board Of Trustees Of The University Of Illinois | Compositions and methods for treating a disease mediated by soluble oligomeric amyloid beta |
| EP2366695A1 (en) * | 2009-11-12 | 2011-09-21 | Selvita S.A. | A compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
| US8604217B2 (en) | 2009-11-12 | 2013-12-10 | Selvita S.A. | Compound, a process for its preparation, a pharmaceutical composition, use of a compound, a method for modulating or regulating serine/threonine kinases and a serine/threonine kinases modulating agent |
| JP2013510824A (ja) | 2009-11-12 | 2013-03-28 | セルビタ エス.エー. | セリン/トレオニンキナーゼを調節または制御するための化合物、その調製のための方法、医薬組成物、化合物の使用、方法ならびにセリン/トレオニンキナーゼ調節剤 |
| US20110230481A2 (en) * | 2009-11-12 | 2011-09-22 | Selvita S.A. | Derivatives of tetrabromobenzimidazole, a process for the preparation thereof, a pharmaceutical composition comprising the same, a method of using the same, a method for modulating or regulating serine/threonine kinases, and serine/threonine kinases modulating agent |
| AU2016315881B2 (en) | 2015-09-03 | 2019-09-19 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Small molecule inhibitors of DYRK1A and uses thereof |
| US12528810B2 (en) | 2018-03-01 | 2026-01-20 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Small molecule inhibitors of DYRK/CLK and uses thereof |
| US10666071B2 (en) | 2018-07-03 | 2020-05-26 | Xentris Wireless, Llc | Inertial user interface portable power bank and method of operation |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3705174A (en) | 1970-02-27 | 1972-12-05 | Merck & Co Inc | Polyhaloalkyl benzimidazoles |
| BR9609888A (pt) | 1995-08-10 | 1999-05-25 | Bayer Ag | Halogenobenzimidazóis |
| ES2367422T3 (es) * | 2001-10-09 | 2011-11-03 | Amgen Inc. | Derivados de imidazol como agentes antiinflamatorios. |
-
2004
- 2004-03-29 PL PL04366690A patent/PL366690A1/pl unknown
-
2005
- 2005-03-29 EP EP05731805A patent/EP1778647A1/en not_active Withdrawn
- 2005-03-29 WO PCT/PL2005/000022 patent/WO2005092866A1/en not_active Ceased
- 2005-03-29 US US10/599,499 patent/US7528259B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7528259B2 (en) | 2009-05-05 |
| US20070213385A1 (en) | 2007-09-13 |
| WO2005092866A1 (en) | 2005-10-06 |
| WO2005092866B1 (en) | 2005-11-17 |
| EP1778647A1 (en) | 2007-05-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DISC | Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications) |