PL367837A1 - Roztwór do przechowywania i perfuzji organów przeznaczonych do transplantacji - Google Patents

Roztwór do przechowywania i perfuzji organów przeznaczonych do transplantacji

Info

Publication number: PL367837A1
Authority: PL; Poland
Prior art keywords: solution; storage; physiologically acceptable; perfusion; awaiting transplantation
Prior art date: 2001-06-14

Application number

PL02367837A

Other languages

English (en)

Other versions

PL206312B1 (pl

Inventor

Arduino Arduini

Tommaso Aureli

Original Assignee

Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-06-14

Filing date

2002-06-13

Publication date

2005-03-07

2002-06-13 Application filed by Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. filed Critical Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.

2005-03-07 Publication of PL367837A1 publication Critical patent/PL367837A1/pl

2010-07-30 Publication of PL206312B1 publication Critical patent/PL206312B1/pl

Links

210000000056 organ Anatomy 0.000 title abstract 2
238000002054 transplantation Methods 0.000 title abstract 2
230000010412 perfusion Effects 0.000 title 1
229910019142 PO4 Inorganic materials 0.000 abstract 2
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 2
239000010452 phosphate Substances 0.000 abstract 2
150000003839 salts Chemical class 0.000 abstract 2
PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical compound C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 abstract 1
BVKZGUZCCUSVTD-UHFFFAOYSA-M Bicarbonate Chemical compound OC([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-M 0.000 abstract 1
VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
230000002378 acidificating effect Effects 0.000 abstract 1
-1 alkanoyl L-carnitine Chemical compound 0.000 abstract 1
239000003963 antioxidant agent Substances 0.000 abstract 1
235000006708 antioxidants Nutrition 0.000 abstract 1
239000002738 chelating agent Substances 0.000 abstract 1
239000008103 glucose Substances 0.000 abstract 1
229910052700 potassium Inorganic materials 0.000 abstract 1
239000011591 potassium Substances 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Substances 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Dentistry (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Zoology (AREA)
Environmental Sciences (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)
Medicinal Preparation (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL367837A 2001-06-14 2002-06-13 Roztwór do utrzymywania i perfuzji organów przeznaczonych do transplantacji PL206312B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IT2001RM000337A ITRM20010337A1 (it)	2001-06-14	2001-06-14	Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
PCT/IT2002/000391 WO2002102149A1 (en)	2001-06-14	2002-06-13	Solution for the storage and perfusion of organs awaiting transplantation

Publications (2)

Publication Number	Publication Date
PL367837A1 true PL367837A1 (pl)	2005-03-07
PL206312B1 PL206312B1 (pl)	2010-07-30

Family

ID=11455594

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL367837A PL206312B1 (pl)	2001-06-14	2002-06-13	Roztwór do utrzymywania i perfuzji organów przeznaczonych do transplantacji

Country Status (15)

Country	Link
US (3)	US7422844B2 (pl)
EP (1)	EP1401270B1 (pl)
JP (1)	JP4268036B2 (pl)
KR (1)	KR100844191B1 (pl)
AT (1)	ATE336166T1 (pl)
CA (1)	CA2450623C (pl)
CY (1)	CY1106202T1 (pl)
DE (1)	DE60213990T2 (pl)
DK (1)	DK1401270T3 (pl)
ES (1)	ES2271290T3 (pl)
IT (1)	ITRM20010337A1 (pl)
MX (1)	MXPA03011461A (pl)
PL (1)	PL206312B1 (pl)
PT (1)	PT1401270E (pl)
WO (1)	WO2002102149A1 (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ITRM20010337A1 (it) *	2001-06-14	2002-12-16	Sigma Tau Ind Farmaceuti	Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.
JP2005095152A (ja) *	2003-08-29	2005-04-14	Japan Tissue Engineering:Kk	培養組織の保存方法
WO2006026304A1 (en) *	2004-08-25	2006-03-09	Ivax Corporation	Cardioprotective formulations and uses thereof
TWI388318B (zh) *	2005-03-10	2013-03-11	西格瑪陶製藥廠	具有改良之生物相容性的含有肉毒鹼之腹膜透析溶液
JP2006347935A (ja) *	2005-06-15	2006-12-28	Masanori Ogata	炎症性サイトカインの産生が関与する疾患の予防及び／又は治療のための医薬
GB0612877D0 (en) *	2006-06-29	2006-08-09	Univ Edinburgh	Organ preservation solution
CN105123670B (zh)	2007-02-17	2018-12-14	哈佛学院董事会	用于进行组织保存的组合物以及方法
CA2715634A1 (en)	2008-02-15	2009-08-27	President And Fellows Of Harvard College	Blood substitute solution
WO2010147111A1 (ja) *	2009-06-15	2010-12-23	トヨタ自動車株式会社	無細胞タンパク質合成溶液、無細胞タンパク質合成キット及びタンパク質合成方法
RU2707532C1 (ru) *	2018-10-11	2019-11-27	Российская Федерация, от имени которой выступает ФОНД ПЕРСПЕКТИВНЫХ ИССЛЕДОВАНИЙ	Способ повышения безопасности и эффективности хранения и транспортировки трансплантируемого органа под давлением консервирующей газовой смеси и устройство на его основе
CN109511650B (zh) *	2018-11-21	2021-06-15	嘉兴莱普晟医疗科技有限公司	一种可以扩大供肝来源的常温机械灌注液
IT201900007446A1 (it)	2019-05-29	2020-11-29	Giuseppe Castellano	Composizione comprendente citrato e carnitina in grado di attivare la produzione della proteina klotho
US20230087020A1 (en) *	2020-03-10	2023-03-23	University Of Florida Research Foundation, Incorporated	Composition for extending viable preservation and shelf-life of organs and tissues

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5498427A (en) *	1990-11-20	1996-03-12	Pasteur Merieux Serums Et Vaccines	Solutions for the perfusion, preservation and reperfusion of organs
IT1261695B (it) *	1993-06-02	1996-05-29	Sigma Tau Ind Farmaceuti	Impiego di l-carnitina e alcanoil l-carnitine nella conservazione del sangue per trasfusioni e soluzioni stabilizzatrici che le contengono.
WO1996018293A1 (en)	1994-12-12	1996-06-20	Charlotte-Mecklenburg Hospital Authority	Organ transplant solutions and method for transplanting an organ
US5707971A (en) *	1995-06-07	1998-01-13	Life Resuscitation Technologies, Inc.	Modulation of glycolytic ATP production
US5834178C1 (en) *	1997-07-09	2002-04-23	Univ Wayne State	Flush-storage solution for donor organs
CA2352485A1 (en) *	1998-11-26	2000-06-02	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Use of fumarate salt of l-carnitine or its alkanoyl derivatives in ischaemia
AU1073400A (en) *	1999-10-11	2001-04-23	Sigma-Tau Industrie Farmaceutiche Riunite S.P.A.	Use of l-carnitine and its alkanoyl derivatives as osmotic agents in solutions for medical use
ITRM20010337A1 (it) *	2001-06-14	2002-12-16	Sigma Tau Ind Farmaceuti	Soluzione per la conservazione e perfuzione di organi in attesa che vengano trapiantati.

2001
- 2001-06-14 IT IT2001RM000337A patent/ITRM20010337A1/it unknown
2002
- 2002-06-13 WO PCT/IT2002/000391 patent/WO2002102149A1/en not_active Ceased
- 2002-06-13 US US10/480,824 patent/US7422844B2/en not_active Expired - Fee Related
- 2002-06-13 PL PL367837A patent/PL206312B1/pl not_active IP Right Cessation
- 2002-06-13 KR KR1020037016372A patent/KR100844191B1/ko not_active Expired - Fee Related
- 2002-06-13 PT PT02745791T patent/PT1401270E/pt unknown
- 2002-06-13 CA CA2450623A patent/CA2450623C/en not_active Expired - Fee Related
- 2002-06-13 DE DE60213990T patent/DE60213990T2/de not_active Expired - Lifetime
- 2002-06-13 EP EP02745791A patent/EP1401270B1/en not_active Expired - Lifetime
- 2002-06-13 DK DK02745791T patent/DK1401270T3/da active
- 2002-06-13 AT AT02745791T patent/ATE336166T1/de active
- 2002-06-13 JP JP2003504747A patent/JP4268036B2/ja not_active Expired - Fee Related
- 2002-06-13 ES ES02745791T patent/ES2271290T3/es not_active Expired - Lifetime
- 2002-06-13 MX MXPA03011461A patent/MXPA03011461A/es active IP Right Grant
2006
- 2006-10-16 CY CY20061101484T patent/CY1106202T1/el unknown
2008
- 2008-01-31 US US12/010,931 patent/US8007993B2/en not_active Expired - Fee Related
- 2008-02-01 US US12/068,055 patent/US7989158B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR20040010712A (ko)	2004-01-31
US7422844B2 (en)	2008-09-09
ES2271290T3 (es)	2007-04-16
KR100844191B1 (ko)	2008-07-04
EP1401270A1 (en)	2004-03-31
ITRM20010337A1 (it)	2002-12-16
EP1401270B1 (en)	2006-08-16
CY1106202T1 (el)	2011-06-08
PL206312B1 (pl)	2010-07-30
US20080166695A1 (en)	2008-07-10
CA2450623A1 (en)	2002-12-27
PT1401270E (pt)	2006-10-31
ATE336166T1 (de)	2006-09-15
JP2004529205A (ja)	2004-09-24
JP4268036B2 (ja)	2009-05-27
DE60213990D1 (de)	2006-09-28
WO2002102149A1 (en)	2002-12-27
ITRM20010337A0 (it)	2001-06-14
MXPA03011461A (es)	2004-07-01
US7989158B2 (en)	2011-08-02
US20080199844A1 (en)	2008-08-21
DK1401270T3 (da)	2006-12-27
CA2450623C (en)	2011-05-10
DE60213990T2 (de)	2007-03-15
US8007993B2 (en)	2011-08-30
US20040156990A1 (en)	2004-08-12

Legal Events

Date	Code	Title	Description
2013-08-30	LAPS	Decisions on the lapse of the protection rights	Effective date: 20120613

Publication	Publication Date	Title
PT1401270E (pt)	2006-10-31	Solucao para o armazenamento e perfusao de orgaos que aguardam transplantacao
DE69127888D1 (de)	1997-11-13	Konservierungslösung für Zellen
NO974108L (no)	1997-11-06	Kryopreserveringsopplösning
FR2785501B1 (fr)	2001-01-05	Solution de perfusion et/ou de conservation et/ou de reperfusion lors de la transplantation d'organes
MX9704374A (es)	1998-02-28	Soluciones para trasplantes de organos y metodo para trasplantar un organo.
AU2696001A (en)	2001-07-31	Physiological medium for perfusing, preserving and storing isolated cell, tissueand organ samples
AU7560994A (en)	1995-03-14	Rinse solution for organs and tissues
IT1247945B (it)	1995-01-05	Agente avente attivita' batteriostatica e battericida
BR9911236A (pt)	2001-03-06	Solução e método de limpeza
MX9800446A (es)	1998-04-30	Sarcosinatos como adyuvantes y activadores de fluazifop-butilo.
ES2039215T3 (es)	1993-09-16	Compuesto inyectable de cefalosporina.
FI853962L (fi)	1986-04-13	Buffrade glutaraldehyd innehaollande steriliserande och desinficerande kompositioner.
CA2266012A1 (en)	1999-01-21	Flush-storage solution for donor organs
MXPA01003046A (es)	2002-07-22	Sarcosinatos como auxiliares de glufosinato.
GB2250439B (en)	1994-07-13	Control of parasitic nematodes
RU95117286A (ru)	1998-01-10	Ирригационный раствор для офтальмологических операций
ES2010682B3 (es)	1989-12-01	Agentes que contienen cobre para la lucha contra los hongos y las bacterias.
EA199900710A1 (ru)	2000-04-24	Кристаллическая гидратированная натриевая соль (е)-4,6-дихлор-3-(2-оксо-1-фенилпирролидин-3-илиденметил)-1н-индол-2-карбоновой кислоты
AR246946A1 (es)	1994-10-31	Procedimiento para la preparacion de cloruro de 2,3-dibromopropionilo.
CA2383324A1 (en)	2001-03-29	Solution for the preservation of hearts
DK1067907T3 (da)	2004-05-17	Okulær udskylningsoplösning
GR3021162T3 (en)	1996-12-31	IMPROVEMENTS IN OR RELATING TO GLASS pH ELECTRODES
UA12350A (uk)	1997-02-28	Спосіб деконсервації сперми бугаїв
RU99123859A (ru)	2001-08-20	Среда инкубации для определения активности каталазы в плазме крови
PT1071410E (pt)	2002-11-29	Composicoes aquosas ionicas que contem levomentol