PL368245A1 - Sposób wytwarzania kwetiapiny - Google Patents
Sposób wytwarzania kwetiapinyInfo
- Publication number
- PL368245A1 PL368245A1 PL04368245A PL36824504A PL368245A1 PL 368245 A1 PL368245 A1 PL 368245A1 PL 04368245 A PL04368245 A PL 04368245A PL 36824504 A PL36824504 A PL 36824504A PL 368245 A1 PL368245 A1 PL 368245A1
- Authority
- PL
- Poland
- Prior art keywords
- chem
- formula
- quetiapine
- manufacture
- metal
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- URKOMYMAXPYINW-UHFFFAOYSA-N quetiapine Chemical compound C1CN(CCOCCO)CCN1C1=NC2=CC=CC=C2SC2=CC=CC=C12 URKOMYMAXPYINW-UHFFFAOYSA-N 0.000 title abstract 2
- 229960004431 quetiapine Drugs 0.000 title abstract 2
- 239000002184 metal Substances 0.000 abstract 2
- 238000007126 N-alkylation reaction Methods 0.000 abstract 1
- TVWHTOUAJSGEKT-UHFFFAOYSA-N chlorine trioxide Chemical compound [O]Cl(=O)=O TVWHTOUAJSGEKT-UHFFFAOYSA-N 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 230000000737 periodic effect Effects 0.000 abstract 1
- 230000002829 reductive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D281/16—[b, f]-condensed
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL04368245A PL368245A1 (pl) | 2004-05-28 | 2004-05-28 | Sposób wytwarzania kwetiapiny |
| ES05460013T ES2296124T3 (es) | 2004-05-28 | 2005-05-27 | Metodo para la preparacion de quetiapina mediante n-alquilacion reductiva de 11-piperazinodibenzo(b,f) (1,4)tioazepina con un aldehido. |
| AT05460013T ATE376545T1 (de) | 2004-05-28 | 2005-05-27 | Verfahren zur hersterllung von quetiapin durch reduktive n-alkylierung von 11- piperazinodibenzo(b,f) (1,4)thioazepin mit einem aldehyd |
| PL05460013T PL1602650T3 (pl) | 2004-05-28 | 2005-05-27 | Sposób wytwarzania kwetiapiny przez redukcyjne N-alkilowanie 11-piperazynodibenzo(B,F)(1,4) tioazepiny za pomocą aldehydu |
| DE602005002972T DE602005002972D1 (de) | 2004-05-28 | 2005-05-27 | Verfahren zur Hersterllung von Quetiapin durch reduktive N-Alkylierung von 11-Piperazinodibenzo(B,F) (1,4)Thioazepin mit einem Aldehyd |
| PT05460013T PT1602650E (pt) | 2004-05-28 | 2005-05-27 | Processo para a preparação de quetiapina por n-alquilação redutiva de 11-piperazinodibenzo(b,f)(1,4)-tioazepina com um aldeído |
| EP05460013A EP1602650B1 (en) | 2004-05-28 | 2005-05-27 | Method for the preparation of quetiapine by reductive N-alkylation of 11-Piperazinodibenzo(B,F) (1,4)Thioazepin with an aldehyde |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PL04368245A PL368245A1 (pl) | 2004-05-28 | 2004-05-28 | Sposób wytwarzania kwetiapiny |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL368245A1 true PL368245A1 (pl) | 2005-12-12 |
Family
ID=34943351
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL04368245A PL368245A1 (pl) | 2004-05-28 | 2004-05-28 | Sposób wytwarzania kwetiapiny |
| PL05460013T PL1602650T3 (pl) | 2004-05-28 | 2005-05-27 | Sposób wytwarzania kwetiapiny przez redukcyjne N-alkilowanie 11-piperazynodibenzo(B,F)(1,4) tioazepiny za pomocą aldehydu |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL05460013T PL1602650T3 (pl) | 2004-05-28 | 2005-05-27 | Sposób wytwarzania kwetiapiny przez redukcyjne N-alkilowanie 11-piperazynodibenzo(B,F)(1,4) tioazepiny za pomocą aldehydu |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1602650B1 (pl) |
| AT (1) | ATE376545T1 (pl) |
| DE (1) | DE602005002972D1 (pl) |
| ES (1) | ES2296124T3 (pl) |
| PL (2) | PL368245A1 (pl) |
| PT (1) | PT1602650E (pl) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7687622B2 (en) | 2005-04-14 | 2010-03-30 | Teva Pharmaceutical Industries, Ltd | Process for preparing quetiapine fumarate |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8705574D0 (en) * | 1987-03-10 | 1987-04-15 | Ici Plc | Preparation of thiazepine compound |
-
2004
- 2004-05-28 PL PL04368245A patent/PL368245A1/pl unknown
-
2005
- 2005-05-27 ES ES05460013T patent/ES2296124T3/es not_active Expired - Lifetime
- 2005-05-27 PT PT05460013T patent/PT1602650E/pt unknown
- 2005-05-27 AT AT05460013T patent/ATE376545T1/de not_active IP Right Cessation
- 2005-05-27 DE DE602005002972T patent/DE602005002972D1/de not_active Expired - Lifetime
- 2005-05-27 PL PL05460013T patent/PL1602650T3/pl unknown
- 2005-05-27 EP EP05460013A patent/EP1602650B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1602650B1 (en) | 2007-10-24 |
| PT1602650E (pt) | 2008-01-22 |
| PL1602650T3 (pl) | 2008-03-31 |
| EP1602650A1 (en) | 2005-12-07 |
| ES2296124T3 (es) | 2008-04-16 |
| ATE376545T1 (de) | 2007-11-15 |
| DE602005002972D1 (de) | 2007-12-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DISC | Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications) |