PL368550A1 - Sposób wytwarzania szybkorozpuszczalnych, wysokoobciążonych kompozycji rybawiryny - Google Patents

Sposób wytwarzania szybkorozpuszczalnych, wysokoobciążonych kompozycji rybawiryny

Info

Publication number: PL368550A1
Authority: PL; Poland
Prior art keywords: high loading; quick dissolving; preparing quick; ribavirin compositions; loading ribavirin
Prior art date: 2001-11-02

Application number

PL02368550A

Other languages

English (en)

Inventor

Amol Singh Matharu

Mahendra R. Patel

Original Assignee

Sandoz Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-11-02

Filing date

2002-10-31

Publication date

2005-04-04

2002-10-31 Application filed by Sandoz Ag filed Critical Sandoz Ag

2005-04-04 Publication of PL368550A1 publication Critical patent/PL368550A1/pl

Links

IWUCXVSUMQZMFG-AFCXAGJDSA-N Ribavirin Chemical compound N1=C(C(=O)N)N=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](CO)O1 IWUCXVSUMQZMFG-AFCXAGJDSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
239000000203 mixture Substances 0.000 title 1
229960000329 ribavirin Drugs 0.000 title 1
HZCAHMRRMINHDJ-DBRKOABJSA-N ribavirin Natural products O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1N=CN=C1 HZCAHMRRMINHDJ-DBRKOABJSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/7056—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Organic Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Oncology (AREA)
Gastroenterology & Hepatology (AREA)
Communicable Diseases (AREA)
Virology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Saccharide Compounds (AREA)

PL02368550A 2001-11-02 2002-10-31 Sposób wytwarzania szybkorozpuszczalnych, wysokoobciążonych kompozycji rybawiryny PL368550A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US33685301P	2001-11-02	2001-11-02

Publications (1)

Publication Number	Publication Date
PL368550A1 true PL368550A1 (pl)	2005-04-04

Family

ID=23317956

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02368550A PL368550A1 (pl)	2001-11-02	2002-10-31	Sposób wytwarzania szybkorozpuszczalnych, wysokoobciążonych kompozycji rybawiryny

Country Status (16)

Country	Link
US (1)	US20030104050A1 (pl)
EP (1)	EP1443911A1 (pl)
JP (1)	JP2005511587A (pl)
KR (1)	KR20050042035A (pl)
CN (1)	CN1585631A (pl)
AU (1)	AU2002350082B9 (pl)
BR (1)	BR0213861A (pl)
CA (1)	CA2465159A1 (pl)
HR (1)	HRP20040384A2 (pl)
HU (1)	HUP0402364A2 (pl)
IL (1)	IL161697A0 (pl)
MX (1)	MXPA04004181A (pl)
NO (1)	NO20042143L (pl)
PL (1)	PL368550A1 (pl)
RU (1)	RU2004116821A (pl)
WO (1)	WO2003039517A1 (pl)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6720000B2 (en)	2001-03-19	2004-04-13	Three Rivers Pharmaceutical, Llc	Process for producing wet ribavirin pellets
US7538094B2 (en) *	2002-09-19	2009-05-26	Three Rivers Pharmacueticals, Llc	Composition containing ribavirin and use thereof
CZ298224B6 (cs) *	2003-04-29	2007-07-25	Pliva Istrazivanje I Razvoj D.O.O.	Farmaceutická kompozice obsahující jako úcinnou látku ribavirin a zpusob její výroby
GEP20094681B (en) *	2004-05-24	2009-05-10	Nycomed Pharma As	Agglomeration of calcium-containing compound obtained by roller compaction
US20080124400A1 (en) *	2004-06-24	2008-05-29	Angiotech International Ag	Microparticles With High Loadings Of A Bioactive Agent
US7723310B2 (en) *	2004-10-18	2010-05-25	Three Rivers Pharmaceuticals, Llc	Large dose ribavirin formulations
US20060110479A1 (en) *	2004-11-24	2006-05-25	Mitra Shankar K	Natural composition for curing hepatitis-B, methods for making the same and pharmaceutical formulations thereof
US8263137B2 (en)	2005-08-04	2012-09-11	Vertical Pharmaceuticals, Inc.	Nutritional supplement for women
US7901710B2 (en)	2005-08-04	2011-03-08	Vertical Pharmaceuticals, Inc.	Nutritional supplement for use under physiologically stressful conditions
US8202546B2 (en)	2005-08-04	2012-06-19	Vertical Pharmaceuticals, Inc.	Nutritional supplement for use under physiologically stressful conditions
MX2009006699A (es) *	2006-12-21	2009-06-30	Mallinckrodt Inc	Composicion y metodo para preparar tabletas oralmente disgregantes que contienen una alta dosis de ingredientes farmaceuticamente activos.
US8202996B2 (en) *	2007-12-21	2012-06-19	Bristol-Myers Squibb Company	Crystalline forms of N-(tert-butoxycarbonyl)-3-methyl-L-valyl-(4R)-4-((7-chloro-4-methoxy-1-isoquinolinyl)oxy)-N- ((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-L-prolinamide
WO2010062996A2 (en) *	2008-11-28	2010-06-03	Adamas Pharmaceuticals, Inc.	Ribavirin composition
EP2295037A1 (en)	2009-09-11	2011-03-16	Ratiopharm GmbH	Pharmaceutical formulation containing Ribavirin
EP2583681A4 (en) *	2010-06-08	2014-01-01	Diagnostico Gam S A Lab De	ORAL VETERINARY COMPOSITION FOR SALMONIDS COMPRISING 1-BETA-D-RIBOFURANOSYL-1H-1,2,4-TRIAZOL-3-CARBOXAMIDE AND USE FOR THE TREATMENT OF INFECTIOUS SALMON ANEMIA (ISA) IN SALMONIDS
EP3307327A1 (en) *	2015-06-09	2018-04-18	Commonwealth Scientific and Industrial Research Organisation	Antiviral conjugates of polyanionic polymer and antiviral drug
CN106806345B (zh) *	2015-11-27	2020-10-13	北京科信必成医药科技发展有限公司	一种利巴韦林掩味颗粒及其制备方法
CN108464972A (zh) *	2018-07-02	2018-08-31	福州大学	一种含有斯诺普利的抗肺动脉高压口服片剂及其制备方法
AU2021292406B2 (en)	2020-06-18	2024-03-14	XWPharma Ltd.	Controlled release granulations of water-soluble active pharmaceutical ingredients
AU2021357705B2 (en)	2020-10-05	2024-09-26	XWPharma Ltd.	Modified release compositions of a gamma-hydroxybutyric acid derivative
CN113304114B (zh) *	2021-06-08	2022-06-10	药大制药有限公司	一种利巴韦林颗粒及其制备方法

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US3277520A (en) *	1963-06-18	1966-10-11	Fuji Denki Kogyo Kabushiki Kai	Method and apparatus for making spherical granules
US3927216A (en) *	1971-06-01	1975-12-16	Icn Pharmaceuticals	1,2,4-Triazol E-3-carboxamides for inhibiting virus infections
US3798209A (en) *	1971-06-01	1974-03-19	Icn Pharmaceuticals	1,2,4-triazole nucleosides
US4211771A (en) *	1971-06-01	1980-07-08	Robins Ronald K	Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
US3976545A (en) *	1973-03-12	1976-08-24	Icn Pharmaceuticals, Inc.	1,2,4-Triazol E-3-carboxamides as antiviral agents
US3948885A (en) *	1973-03-19	1976-04-06	Icn Pharmaceuticals, Inc.	5-Hydroxyl-1,2,3-triazole-4-carboxamide nucleoside
US4138547A (en) *	1977-12-22	1979-02-06	Icn Pharmaceuticals, Inc.	Process for preparing 1,2,4-triazole nucleosides
US4439453A (en) *	1980-12-22	1984-03-27	Monsanto Company	Directly compressible acetaminophen granulation
GB9009861D0 (en) *	1990-05-02	1990-06-27	Glaxo Group Ltd	Chemical compounds
US5405837A (en) *	1993-05-18	1995-04-11	Indiana University Foundation	Method for the treatment of neoplastic disease utilizing tiazofurin and ribavirin
ES2214551T3 (es) *	1995-11-02	2004-09-16	Schering Corporation	Terapia de infusion continua de citocinas a baja dosis.
US5908621A (en) *	1995-11-02	1999-06-01	Schering Corporation	Polyethylene glycol modified interferon therapy
US6150337A (en) *	1996-01-23	2000-11-21	Icn Pharmaceuticals, Inc.	Specific modulation of Th1/Th2 cytokine expression by Ribavirin in activated T-lymphocytes
US5767097A (en) *	1996-01-23	1998-06-16	Icn Pharmaceuticals, Inc.	Specific modulation of Th1/Th2 cytokine expression by ribavirin in activated T-lymphocytes
SK284054B6 (sk) *	1996-10-16	2004-08-03	Icn Pharmaceuticals, Inc.	Substituované triazolové nukleozidy, farmaceutický prostriedok s ich obsahom a ich použitie
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US6472373B1 (en) *	1997-09-21	2002-10-29	Schering Corporation	Combination therapy for eradicating detectable HCV-RNA in antiviral treatment naive patients having chronic hepatitis C infection
US5914128A (en) *	1997-12-22	1999-06-22	Schering Corporation	Orally administrable solid dosage form
DK0991415T3 (da) *	1997-12-22	2003-06-16	Schering Corp	Faste, oralt indgivelige dosisformer for ribavirin og fremgangsmåde til fremstilling af disse
US5916594A (en) *	1997-12-22	1999-06-29	Schering Corporation	Process of making solid ribavirin dosage forms
US20030104048A1 (en) *	1999-02-26	2003-06-05	Lipocine, Inc.	Pharmaceutical dosage forms for highly hydrophilic materials
US6541014B2 (en) *	2000-10-13	2003-04-01	Advancis Pharmaceutical Corp.	Antiviral product, use and formulation thereof
US6720000B2 (en) *	2001-03-19	2004-04-13	Three Rivers Pharmaceutical, Llc	Process for producing wet ribavirin pellets

2002
- 2002-10-31 PL PL02368550A patent/PL368550A1/pl not_active Application Discontinuation
- 2002-10-31 AU AU2002350082A patent/AU2002350082B9/en not_active Ceased
- 2002-10-31 EP EP02786613A patent/EP1443911A1/en not_active Withdrawn
- 2002-10-31 WO PCT/US2002/034899 patent/WO2003039517A1/en not_active Ceased
- 2002-10-31 KR KR1020047006543A patent/KR20050042035A/ko not_active Withdrawn
- 2002-10-31 MX MXPA04004181A patent/MXPA04004181A/es unknown
- 2002-10-31 CN CNA028222172A patent/CN1585631A/zh active Pending
- 2002-10-31 HR HR20040384A patent/HRP20040384A2/hr not_active Application Discontinuation
- 2002-10-31 BR BR0213861-1A patent/BR0213861A/pt not_active IP Right Cessation
- 2002-10-31 US US10/285,188 patent/US20030104050A1/en not_active Abandoned
- 2002-10-31 RU RU2004116821/15A patent/RU2004116821A/ru not_active Application Discontinuation
- 2002-10-31 CA CA002465159A patent/CA2465159A1/en not_active Abandoned
- 2002-10-31 JP JP2003541808A patent/JP2005511587A/ja active Pending
- 2002-10-31 HU HU0402364A patent/HUP0402364A2/hu unknown
- 2002-10-31 IL IL16169702A patent/IL161697A0/xx unknown
2004
- 2004-05-25 NO NO20042143A patent/NO20042143L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
KR20050042035A (ko)	2005-05-04
NO20042143L (no)	2004-05-25
EP1443911A1 (en)	2004-08-11
CN1585631A (zh)	2005-02-23
AU2002350082B2 (en)	2006-07-20
CA2465159A1 (en)	2003-05-15
MXPA04004181A (es)	2005-01-25
JP2005511587A (ja)	2005-04-28
WO2003039517A1 (en)	2003-05-15
HUP0402364A2 (hu)	2005-02-28
HRP20040384A2 (en)	2005-08-31
AU2002350082B9 (en)	2006-08-31
BR0213861A (pt)	2004-12-21
IL161697A0 (en)	2004-09-27
US20030104050A1 (en)	2003-06-05
RU2004116821A (ru)	2005-04-20

Legal Events

Date	Code	Title	Description
2010-03-31	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
IL161697A0 (en)	2004-09-27	Process for preparing quick dissolving, high loading ribavirin compositions
IL165977A (en)	2010-12-30	Substituted pyrimidinylaminobenzamides , process for the preparation thereof and pharmaceutical compositions comprising the same
HUP0402264A3 (en)	2010-03-29	Substituted 2-thio-3,5-dicyano-4-phenyl-6-aminopyridines process for preparing them, pharmaceutical compositions containing them and use thereof
HRP20050328A2 (en)	2005-06-30	Process for the preparation of (s,s)-cis-2-benzhyd
EG23299A (en)	2004-11-30	Process for preparing 1-octene.
IL156219A0 (en)	2003-12-23	Process for preparing stabilized compositions based on polyamide
HUP0401296A3 (en)	2004-11-29	Novel processes for producing pyrimidinon derivatives
MY137678A (en)	2009-02-27	Process for preparing formaldehyde
IL159994A0 (en)	2004-06-20	Process for preparing 4-aminodiphenylamine
IL166698A0 (en)	2006-01-15	Process for preparing paste-extruded sulfonamide compositions
ZA200402472B (en)	2004-12-14	Method for preparing benzenesulfonyl compounds.
ZA200408857B (en)	2005-10-05	Low isoflavones, high saponins soy protein productand process for producing the same.
SG115596A1 (en)	2005-10-28	Process for preparing tert-butanol
PL375695A1 (pl)	2005-12-12	Sposób wytwarzania (S) pantoprazolu
ZA200108623B (en)	2002-06-07	Process for preparing imidachloprid.
PL1561754T3 (pl)	2007-07-31	Sposób wytwarzania związków kompleksowych 1,2-diaminocykloheksan-platyna(II)
PL364836A1 (pl)	2004-12-27	Predyspersje, sposób ich wytwarzania, kompozycje do ich wytwarzania i sposób wytwarzania takich kompozycji
HUP0201837A3 (en)	2013-07-29	Process for preparation n-carboxy-anhydrides
TW484471U (en)	2002-04-21	Extension sideboard structure for round saw machine
ZA200305338B (en)	2004-07-12	An improved process for preparing pure ondansetron hydrochloride dihydrate.
AP2005003229A0 (en)	2005-03-31	Process for preparing of paclitaxel.
HK1070811A (en)	2005-06-30	Process for preparing quick dissolving, high loading ribavirin compositions
SI1888537T1 (sl)	2014-01-31	Postopek priprave 4-((1,6-dihidro-6-okso-2-pirimidinil)amino benzonitrila
PL371913A1 (pl)	2005-07-11	Sposoby syntezy beta-L-5-fluoro-2',3'-dideoksy-2',3'-didehydrocytydyny (beta-L-FD4C)
AU2003248987A8 (en)	2004-02-23	Process for preparing 7-azaindoles