PL3698630T3 - Podawanie i monitorowanie poziomu tlenku azotu w płynach ex vivo - Google Patents

Podawanie i monitorowanie poziomu tlenku azotu w płynach ex vivo

Info

Publication number
PL3698630T3
PL3698630T3 PL20169811.5T PL20169811T PL3698630T3 PL 3698630 T3 PL3698630 T3 PL 3698630T3 PL 20169811 T PL20169811 T PL 20169811T PL 3698630 T3 PL3698630 T3 PL 3698630T3
Authority
PL
Poland
Prior art keywords
monitoring
fluid
nitrous oxide
vivo delivery
vivo
Prior art date
Application number
PL20169811.5T
Other languages
English (en)
Inventor
Jim POTENZIANO
Douglas R HANSELL
Jeff Griebel
Eddie COSTA
Lisa Cooper
Original Assignee
Mallinckrodt Pharmaceuticals Ireland Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Pharmaceuticals Ireland Limited filed Critical Mallinckrodt Pharmaceuticals Ireland Limited
Publication of PL3698630T3 publication Critical patent/PL3698630T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/12Chemical aspects of preservation
    • A01N1/122Preservation or perfusion media
    • A01N1/126Physiologically active agents, e.g. antioxidants or nutrients
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • A01N1/14Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142Apparatus
    • A01N1/143Apparatus for organ perfusion
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3623Means for actively controlling temperature of blood
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0634Cells from the blood or the immune system
    • C12N5/0641Erythrocytes
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10Preservation of living parts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/24Heavy metals; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Environmental Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dentistry (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • External Artificial Organs (AREA)
PL20169811.5T 2013-03-15 2014-12-01 Podawanie i monitorowanie poziomu tlenku azotu w płynach ex vivo PL3698630T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361787865P 2013-03-15 2013-03-15
US14/095,621 US9629358B2 (en) 2013-03-15 2013-12-03 Administration and monitoring of nitric oxide in ex vivo fluids

Publications (1)

Publication Number Publication Date
PL3698630T3 true PL3698630T3 (pl) 2024-08-05

Family

ID=51528684

Family Applications (1)

Application Number Title Priority Date Filing Date
PL20169811.5T PL3698630T3 (pl) 2013-03-15 2014-12-01 Podawanie i monitorowanie poziomu tlenku azotu w płynach ex vivo

Country Status (12)

Country Link
US (3) US9629358B2 (pl)
EP (2) EP3698630B1 (pl)
JP (2) JP6612231B2 (pl)
AU (3) AU2014357412B2 (pl)
CA (3) CA2931943C (pl)
DK (1) DK3698630T3 (pl)
ES (1) ES2805366T3 (pl)
FI (1) FI3698630T3 (pl)
MX (2) MX381625B (pl)
PL (1) PL3698630T3 (pl)
PT (1) PT3698630T (pl)
WO (1) WO2015084698A2 (pl)

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CN113287600B (zh) 2014-06-02 2022-08-19 特兰斯迈迪茨公司 对离体肝脏灌注的灌注回路和系统以及对其保存的系统
AU2015361996B2 (en) 2014-12-12 2019-09-26 Transmedics, Inc. Apparatus and method for organ perfusion
IL310004B2 (en) 2015-09-09 2025-04-01 Transmedics Inc Endotracheal tube for an extracorporeal organ therapy system
AU2016366699A1 (en) * 2015-12-11 2018-06-28 Vero Biotech LLC Method and apparatus for administering gases including nitric oxide to address fibrosis
KR102905144B1 (ko) * 2016-02-12 2025-12-31 말린크로트 파마슈티칼스 아일랜드 리미티드 좌심실 보조 장치에 의한 흡인성 일산화질소의 사용 및 모니터링
US11540509B2 (en) 2016-05-30 2023-01-03 Tevosol, Inc. Apparatus and method for ex vivo lung ventilation with a varying exterior pressure
CA3036361A1 (en) * 2016-09-10 2018-03-15 Vero Biotech LLC System and method for portable nitric oxide delivery
TWI656890B (zh) * 2017-07-12 2019-04-21 英屬開曼群島商怡忠國際有限公司 體外生命支持系統
CN111107742A (zh) * 2017-08-25 2020-05-05 马林克罗特医疗产品知识产权公司 提高器官生存能力的方法
US11881119B2 (en) * 2017-12-06 2024-01-23 Cilag Gmbh International Modeling air leaks in lungs
GB2587350B (en) * 2019-09-23 2021-12-15 Royal Papworth Hospital Nhs Found Trust Organ perfusion system and method
WO2021177164A1 (ja) * 2020-03-05 2021-09-10 テルモ株式会社 医療デバイス
GB2596041B (en) * 2020-03-26 2024-12-04 Univ Newcastle System and Method for Monitoring Body Tissue
CN113797404B (zh) * 2021-01-06 2023-05-09 郝云玲 一种向血液中补充一氧化氮(no)的装置
EP4137170A1 (en) 2021-07-29 2023-02-22 Tim Bast Purge fluid generator for membrane oxygenation
CN113975505B (zh) * 2021-11-08 2023-12-19 中山大学中山眼科中心 用于眼球灌注的体外循环系统
WO2024129417A1 (en) 2022-12-16 2024-06-20 Fresenius Medical Care Holdings, Inc. Systems and methods for using nitric oxide in dialysis
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WO2025213152A1 (en) * 2024-04-06 2025-10-09 The Board Of Trustees Of The Leland Stanford Junior University Cardiac ex vivo preservation system compatible for use with any oxygenator and pump

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Also Published As

Publication number Publication date
MX2016007057A (es) 2017-02-02
CA2931943C (en) 2021-11-30
EP3086638B1 (en) 2020-04-22
US20140272920A1 (en) 2014-09-18
AU2014357412B2 (en) 2018-03-01
MX2021001867A (es) 2021-04-19
FI3698630T3 (fi) 2024-05-24
US9629358B2 (en) 2017-04-25
CA3135254A1 (en) 2015-06-11
JP2020033368A (ja) 2020-03-05
MX381625B (es) 2025-03-12
EP3698630A1 (en) 2020-08-26
EP3086638A2 (en) 2016-11-02
JP6884190B2 (ja) 2021-06-09
WO2015084698A3 (en) 2015-11-05
US20150093738A1 (en) 2015-04-02
PT3698630T (pt) 2024-05-31
DK3698630T3 (da) 2024-05-21
JP2017503762A (ja) 2017-02-02
AU2018203630A1 (en) 2018-06-21
JP6612231B2 (ja) 2019-11-27
CA2931943A1 (en) 2015-06-11
CA3233961A1 (en) 2015-06-11
ES2805366T3 (es) 2021-02-11
CA3135254C (en) 2024-05-14
US11291202B2 (en) 2022-04-05
US20170215411A1 (en) 2017-08-03
WO2015084698A2 (en) 2015-06-11
AU2018203630B2 (en) 2019-08-29
AU2014357412A1 (en) 2016-06-16
EP3698630B1 (en) 2024-03-13
AU2019246828A1 (en) 2019-11-07
AU2019246828B2 (en) 2021-12-02

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