PL3702775T3 - Sposób oznaczania zdolności wiązania w układzie chromatograficznym - Google Patents
Sposób oznaczania zdolności wiązania w układzie chromatograficznymInfo
- Publication number
- PL3702775T3 PL3702775T3 PL20168846.2T PL20168846T PL3702775T3 PL 3702775 T3 PL3702775 T3 PL 3702775T3 PL 20168846 T PL20168846 T PL 20168846T PL 3702775 T3 PL3702775 T3 PL 3702775T3
- Authority
- PL
- Poland
- Prior art keywords
- binding capacity
- chromatographic system
- determining binding
- determining
- chromatographic
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
- B01D15/428—Frontal mode
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/42—Flow patterns using counter-current
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/26—Conditioning of the fluid carrier; Flow patterns
- G01N30/38—Flow patterns
- G01N30/46—Flow patterns using more than one column
- G01N30/468—Flow patterns using more than one column involving switching between different column configurations
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/78—Detectors specially adapted therefor using more than one detector
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
- G01N2030/889—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 monitoring the quality of the stationary phase; column performance
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/86—Signal analysis
- G01N30/8665—Signal analysis for calibrating the measuring apparatus
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0950494 | 2009-06-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3702775T3 true PL3702775T3 (pl) | 2026-03-30 |
Family
ID=43386770
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL20168846.2T PL3702775T3 (pl) | 2009-06-26 | 2010-06-21 | Sposób oznaczania zdolności wiązania w układzie chromatograficznym |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20120091063A1 (pl) |
| EP (2) | EP2446257B1 (pl) |
| CN (1) | CN102472731B (pl) |
| PL (1) | PL3702775T3 (pl) |
| WO (1) | WO2010151214A1 (pl) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2578286A1 (en) | 2011-10-04 | 2013-04-10 | Merck Patent GmbH | Method and apparatus for chromatographic purification |
| US10201767B2 (en) | 2013-02-19 | 2019-02-12 | Ge Healthcare Bio-Sciences Ab | Chromatography system and method |
| US10948483B2 (en) | 2013-04-08 | 2021-03-16 | Chromacon Ag | Method for control, monitoring and/or optimization of a chromatographic process |
| US10099156B2 (en) * | 2013-04-08 | 2018-10-16 | Chromacon Ag | Chromatographic purification method |
| DE102014010353B4 (de) | 2014-07-10 | 2024-09-12 | Sartorius Stedim Biotech Gmbh | Vorrichtung, Verwendung dieser Vorrichtung und Verfahren für die Stofftrennung mit verbesserter Ausnutzung der Kapazität chromatographischer Medien |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| EP3234590B1 (en) | 2014-12-18 | 2021-10-06 | Cytiva Sweden AB | Method and system for determining saturation level of a chromatography column based on pressure detection |
| US11835501B2 (en) * | 2015-07-13 | 2023-12-05 | Sartorius Stedim Chromatography Systems Ltd. | Optimizing operating binding capacity for a multiple column chromatography process |
| GB201517282D0 (en) * | 2015-09-30 | 2015-11-11 | Ge Healthcare Bio Sciences Ab | A chromatography system and a method therefor |
| EP3173782A1 (de) | 2015-11-26 | 2017-05-31 | Karlsruher Institut für Technologie | Verfahren zur steuerung kontinuierlicher chromatographie und multisäulen-chromatographie-anordnung |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| US10513537B2 (en) | 2016-05-11 | 2019-12-24 | Ge Healthcare Bioprocess R&D Ab | Separation matrix |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| WO2017194593A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of cleaning and/or sanitizing a separation matrix |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| WO2017194592A1 (en) | 2016-05-11 | 2017-11-16 | Ge Healthcare Bioprocess R&D Ab | Method of storing a separation matrix |
| US11519851B2 (en) * | 2016-09-17 | 2022-12-06 | C Technologies Inc. | Monitoring of compounds |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| GB201622342D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in continuos chromatography |
| GB201622343D0 (en) * | 2016-12-29 | 2017-02-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| EP3586123B1 (en) * | 2017-02-21 | 2023-03-08 | Cytiva Sweden AB | Methods and systems for adapting pathlength and/or wavelength of a uv-absorbance cell in a chromatography system |
| GB201703258D0 (en) * | 2017-02-28 | 2017-04-12 | Ge Healthcare Bio Sciences Ab | Parallel separation and washing |
| EP3381530A1 (fr) | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| EP3381529A1 (fr) | 2017-03-29 | 2018-10-03 | EMD Millipore Corporation | Installation de traitement de liquide biologique |
| JP6990902B2 (ja) * | 2017-03-31 | 2022-01-12 | 株式会社日立ハイテクサイエンス | 液体クロマトグラフ装置 |
| GB201709531D0 (en) * | 2017-06-15 | 2017-08-02 | Ge Healthcare Bio Sciences Ab | Method and apparatus for determining one or more buffer composition recipes |
| US11119079B2 (en) * | 2017-08-17 | 2021-09-14 | Daylight Solutions, Inc. | Liquid chromatography analyzer system with on-line analysis of eluting fractions |
| PL3512616T5 (pl) * | 2017-11-16 | 2022-12-19 | Chromacon Ag | Sposób monitorowania, oceny i sterowania cyklicznym procesem oczyszczania techniką chromatograficzną |
| JP7366020B2 (ja) * | 2017-12-11 | 2023-10-20 | マルバーン パナリティカル リミテッド | サイズ排除クロマトグラフィーによる粒径分布の決定 |
| GB201810772D0 (en) | 2018-06-29 | 2018-08-15 | Ge Healthcare Bio Sciences Ab | Method in bioprocess purification system |
| WO2020076818A1 (en) * | 2018-10-09 | 2020-04-16 | C Technologies, Inc. | Mass control system for chromatography |
| CN111068360A (zh) * | 2018-10-22 | 2020-04-28 | 信达生物制药(苏州)有限公司 | 组合式层析装置和连续流层析方法 |
| US11867673B2 (en) * | 2019-03-22 | 2024-01-09 | Indian Institute Of Technology Delhi | NIR based real-time control of loading in protein a chromatography |
| GB201916889D0 (en) * | 2019-11-20 | 2020-01-01 | Ge Healthcare Bio Sciences Ab | Method for determining an operating flow rate for a chromatographic column in an hplc system |
| CN117377875A (zh) | 2021-05-25 | 2024-01-09 | 勃林格殷格翰国际公司 | 用于连续生物生产的使用紫外测量的滴定法 |
| WO2023043718A1 (en) * | 2021-09-14 | 2023-03-23 | Sanofi | Chromatography system |
| DE102021130958A1 (de) * | 2021-11-25 | 2023-05-25 | MionTec GmbH | Ionenaustauscheranlage zur Verwendung in Ionenaustauschprozessen |
| EP4273542A1 (en) | 2022-05-06 | 2023-11-08 | Sartorius Stedim Biotech GmbH | Method of referencing an analyte measurement in a purification system |
| CN114832439A (zh) * | 2022-06-07 | 2022-08-02 | 杭州奕安济世生物药业有限公司 | 一种自动控制连续层析上样载量的方法和层析方法 |
| EP4498079A1 (en) | 2023-07-28 | 2025-01-29 | Sartorius Stedim Biotech GmbH | Method of controlling a biopharmaceutical purification process |
| EP4610645A1 (en) | 2024-02-29 | 2025-09-03 | Sartorius Stedim Biotech GmbH | Methods for processing and/or purification of a biological product involving multi-angle light scattering as analytical tool for process control |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3291726A (en) | 1964-05-04 | 1966-12-13 | Universal Oil Prod Co | Continuous simulated countercurrent sorption process employing desorbent made in said process |
| WO1992002815A2 (en) * | 1990-08-10 | 1992-02-20 | Perseptive Biosystems, Inc. | Quantitative analysis and monitoring of protein structure by subtractive chromatography |
| CA2120327A1 (en) * | 1991-09-30 | 1993-04-15 | Noubar B. Afeyan | Protein chromatography system |
| US5457260A (en) | 1993-12-27 | 1995-10-10 | Uop | Control process for simulated moving adsorbent bed separations |
| US6054047A (en) * | 1998-03-27 | 2000-04-25 | Synsorb Biotech, Inc. | Apparatus for screening compound libraries |
| DE10105728B4 (de) | 2001-02-08 | 2005-09-15 | Siemens Ag | Verfahren zur gaschromatographischen Analyse einer Probe |
| US7178386B1 (en) * | 2003-04-10 | 2007-02-20 | Nanostream, Inc. | Parallel fluid processing systems and methods |
| US7396973B1 (en) * | 2005-02-02 | 2008-07-08 | Winter George R | Simulated moving bed adsorptive separation process for handling multiple feedstocks |
| EP1716900A1 (en) | 2005-04-29 | 2006-11-02 | Eidgenössische Technische Hochschule Zürich | Method and device for chromatographic purification |
| US8920645B2 (en) * | 2005-12-07 | 2014-12-30 | Tarpon Biosystems Inc. | Disposable chromatography valves and system |
| WO2008153472A1 (en) | 2007-06-15 | 2008-12-18 | Ge Healthcare Bio-Sciences Ab | Chromatography method |
| CN201116921Y (zh) * | 2007-11-20 | 2008-09-17 | 北京佰尔发玛科技发展有限公司 | 一种多功能大β值高效逆流色谱仪 |
| US8968560B2 (en) | 2007-12-06 | 2015-03-03 | Schlumberger Technology Corporation | Chromatography using multiple detectors |
-
2010
- 2010-06-21 PL PL20168846.2T patent/PL3702775T3/pl unknown
- 2010-06-21 EP EP10792416.9A patent/EP2446257B1/en active Active
- 2010-06-21 WO PCT/SE2010/050700 patent/WO2010151214A1/en not_active Ceased
- 2010-06-21 EP EP20168846.2A patent/EP3702775B1/en active Active
- 2010-06-21 US US13/380,170 patent/US20120091063A1/en not_active Abandoned
- 2010-06-21 CN CN201080029549.3A patent/CN102472731B/zh active Active
-
2020
- 2020-08-18 US US16/995,933 patent/US20200378934A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP3702775A1 (en) | 2020-09-02 |
| US20120091063A1 (en) | 2012-04-19 |
| EP2446257A4 (en) | 2014-09-10 |
| CN102472731A (zh) | 2012-05-23 |
| EP3702775B1 (en) | 2026-01-07 |
| EP2446257B1 (en) | 2020-06-03 |
| US20200378934A1 (en) | 2020-12-03 |
| WO2010151214A1 (en) | 2010-12-29 |
| CN102472731B (zh) | 2016-01-13 |
| EP2446257A1 (en) | 2012-05-02 |
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