PL370346A1 - An enantiomerically pure diarylmethylpiperazine and methods of using same - Google Patents

An enantiomerically pure diarylmethylpiperazine and methods of using same

Info

Publication number
PL370346A1
PL370346A1 PL02370346A PL37034602A PL370346A1 PL 370346 A1 PL370346 A1 PL 370346A1 PL 02370346 A PL02370346 A PL 02370346A PL 37034602 A PL37034602 A PL 37034602A PL 370346 A1 PL370346 A1 PL 370346A1
Authority
PL
Poland
Prior art keywords
diarylmethylpiperazine
methods
same
enantiomerically pure
enantiomerically
Prior art date
Application number
PL02370346A
Other languages
English (en)
Polish (pl)
Inventor
Kwen-Jen Chang
Original Assignee
Ardent Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ardent Pharmaceuticals, Inc. filed Critical Ardent Pharmaceuticals, Inc.
Publication of PL370346A1 publication Critical patent/PL370346A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/32—Alcohol-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Addiction (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Otolaryngology (AREA)
  • Transplantation (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
PL02370346A 2001-09-25 2002-09-25 An enantiomerically pure diarylmethylpiperazine and methods of using same PL370346A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32471201P 2001-09-25 2001-09-25

Publications (1)

Publication Number Publication Date
PL370346A1 true PL370346A1 (en) 2005-05-16

Family

ID=23264757

Family Applications (1)

Application Number Title Priority Date Filing Date
PL02370346A PL370346A1 (en) 2001-09-25 2002-09-25 An enantiomerically pure diarylmethylpiperazine and methods of using same

Country Status (16)

Country Link
US (1) US6924288B2 (fr)
EP (1) EP1438051A4 (fr)
JP (1) JP2005505575A (fr)
KR (1) KR20040041171A (fr)
CN (1) CN1558765B (fr)
AU (1) AU2002341832B2 (fr)
BR (1) BR0212742A (fr)
CA (1) CA2459577C (fr)
IL (2) IL160794A0 (fr)
MX (1) MXPA04002813A (fr)
NO (1) NO325958B1 (fr)
NZ (1) NZ531875A (fr)
PL (1) PL370346A1 (fr)
RU (1) RU2309153C2 (fr)
WO (1) WO2003026660A1 (fr)
ZA (1) ZA200402325B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7189725B2 (en) * 2001-09-25 2007-03-13 Mount Cook Biosciences, Inc. Enantiomerically pure opioid diarylmethylpiperazine as a cardioprotection agent
US7314880B2 (en) * 2003-01-02 2008-01-01 Mount Cook Biosciences, Inc. Cardioprotective delta opioid receptor agonists and methods of using same
WO2006113468A2 (fr) * 2005-04-14 2006-10-26 Mount Cook Biosciences, Inc. Compositions de nouveaux composes opioides et methode d'utilisation associee
US20070197786A1 (en) * 2005-07-22 2007-08-23 Kwen-Jen Chang Enantiomerically pure opioid diarylmethylpiperazine
KR101319390B1 (ko) * 2007-04-25 2013-10-17 엘지전자 주식회사 대중 교통 정보를 제공하고 이를 이용하는 방법 및 장치
CN105646332B (zh) * 2014-11-09 2018-05-25 复旦大学 氨基甲基哌啶类衍生物及其制备方法和药物用途
CA3061323C (fr) 2017-04-30 2023-09-26 Versi Group, Llc Opioide destine a etre utilise pour reduire et/ou traiter la pharmacodependance

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020052007A1 (en) 1992-02-03 2002-05-02 Chang Kwen Jen Diarylmethylbenzylpiperazines and corresponding halobenzyl derivatives
US5985880A (en) * 1996-06-05 1999-11-16 Delta Pharmaceuticals Compositions and methods for reducing respiratory depression and attendant side effects of mu opioid compounds
GB9202238D0 (en) * 1992-02-03 1992-03-18 Wellcome Found Compounds
US5807858A (en) * 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
PT711289E (pt) * 1993-07-30 2001-02-28 Delta Pharmaceuticals Inc Compostos piperazina utilizados em terapia

Also Published As

Publication number Publication date
EP1438051A4 (fr) 2005-01-05
JP2005505575A (ja) 2005-02-24
NO20041729L (no) 2004-06-25
KR20040041171A (ko) 2004-05-14
CN1558765A (zh) 2004-12-29
RU2309153C2 (ru) 2007-10-27
IL160794A0 (en) 2004-08-31
BR0212742A (pt) 2004-10-05
NO325958B1 (no) 2008-08-25
CN1558765B (zh) 2012-01-04
AU2002341832B2 (en) 2008-10-30
CA2459577C (fr) 2012-01-24
WO2003026660A1 (fr) 2003-04-03
EP1438051A1 (fr) 2004-07-21
IL160794A (en) 2012-08-30
US20030114462A1 (en) 2003-06-19
US6924288B2 (en) 2005-08-02
CA2459577A1 (fr) 2003-04-03
ZA200402325B (en) 2005-01-13
NZ531875A (en) 2006-10-27
RU2004107850A (ru) 2005-04-20
MXPA04002813A (es) 2005-06-06

Similar Documents

Publication Publication Date Title
AU2002364528A8 (en) Bio-implant and method of making the same
PL375691A1 (en) Imidazolopyridines and methods of making and using the same
AU2002314466A1 (en) Withasol and methods of use
AU2002324775A8 (en) Architecture tool and methods of use
AU2003275311A1 (en) Solid micro-perforators and methods of use
AU2003288902A1 (en) Microcapsules and methods of use
AU2002250331A1 (en) 7-pyrollyl tetracycline compounds and methods of use thereof
AU2002255752A1 (en) 9-aminoacyl tetracycline compounds and methods of use thereof
AU2003259717A8 (en) Modulators of rabggt and methods of use thereof
AU2002225954A1 (en) Dipeptidylpeptidases and methods of use
IL160835A0 (en) Catheter and method of using same
EP1438387A4 (fr) Procedes de fabrication de glycomolecules a activite amelioree, et utilisations de ces dernieres
AU1334602A (en) Osteopontin-coated surfaces and methods of use
IL211958A0 (en) Lactone formulations and method of use
GB2390505B (en) Loudspeaker and method of making same
AU2002324895A8 (en) Cosmetic kit and method
AU2002363938A8 (en) Methods and use of motoneuronotropic factors
IL160794A0 (en) An enantiomerically pure diarylmethylpiperazine and methods of using same
AU2003287802A1 (en) Palpometer and methods of use thereof
AU2003216354A8 (en) Modulators of paraptosis and related methods
GB0121776D0 (en) Television system and method of use thereof
GB2394359B (en) Microelctronic device and method of its manufacture
AU2002306845A1 (en) Telomerase inhibitors and methods of their use
EP1414427A4 (fr) Compositions a base de kavalactone et leurs procedes d'utilisation
WO2003016502A9 (fr) Tramdorines et procede d'utilisation de tramdorines

Legal Events

Date Code Title Description
DISC Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications)