PL370412A1 - Pseudopolimorficzne postacie karwedilolu - Google Patents

Pseudopolimorficzne postacie karwedilolu

Info

Publication number: PL370412A1
Authority: PL; Poland
Prior art keywords: carvedilol; pseudopolymorphic forms; forms; pseudopolymorphic; carbazolyloxy
Prior art date: 2001-09-28

Application number

PL02370412A

Other languages

English (en)

Inventor

Andre Gerard Bubendorf

Rolf-Dieter Gabel

Michael Hennig

Siegfried Krimmer

Guenter Neugebauer

Walter Preis

Alexander Wirl

Original Assignee

F.Hoffmann-La Roche Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-28

Filing date

2002-09-18

Publication date

2005-05-30

2002-09-18 Application filed by F.Hoffmann-La Roche Ag filed Critical F.Hoffmann-La Roche Ag

2005-05-30 Publication of PL370412A1 publication Critical patent/PL370412A1/pl

Links

NPAKNKYSJIDKMW-UHFFFAOYSA-N carvedilol Chemical compound COC1=CC=CC=C1OCCNCC(O)COC1=CC=CC2=NC3=CC=C[CH]C3=C12 NPAKNKYSJIDKMW-UHFFFAOYSA-N 0.000 title abstract 2
229960004195 carvedilol Drugs 0.000 title abstract 2
125000000031 ethylamino group Chemical group [H]C([H])([H])C([H])([H])N([H])[*] 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
Life Sciences & Earth Sciences (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Urology & Nephrology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Indole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL02370412A 2001-09-28 2002-09-18 Pseudopolimorficzne postacie karwedilolu PL370412A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01123422		2001-09-28

Publications (1)

Publication Number	Publication Date
PL370412A1 true PL370412A1 (pl)	2005-05-30

Family

ID=8178782

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02370412A PL370412A1 (pl)	2001-09-28	2002-09-18	Pseudopolimorficzne postacie karwedilolu

Country Status (20)

Country	Link
US (3)	US20030119893A1 (pl)
EP (1)	EP1432681B1 (pl)
JP (1)	JP2005507899A (pl)
KR (1)	KR100752549B1 (pl)
CN (1)	CN1308307C (pl)
AR (1)	AR036689A1 (pl)
AT (1)	ATE369339T1 (pl)
AU (1)	AU2002338726B2 (pl)
BR (1)	BR0212927A (pl)
CA (1)	CA2460486A1 (pl)
DE (1)	DE60221683T2 (pl)
ES (1)	ES2291503T3 (pl)
GT (1)	GT200200198A (pl)
MX (1)	MXPA04002826A (pl)
PA (1)	PA8555201A1 (pl)
PE (1)	PE20030448A1 (pl)
PL (1)	PL370412A1 (pl)
RU (1)	RU2308449C2 (pl)
UY (1)	UY27461A1 (pl)
WO (1)	WO2003029214A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL153688A0 (en) *	2000-06-28	2003-07-06	Teva Pharma	Carvedilol
PL371409A1 (pl) *	2002-01-15	2005-06-13	Teva Pharmaceutical Industries Ltd.	Krystaliczne substancje stałe karwedilolu i sposoby ich wytwarzania
MXPA04012923A (es)	2002-06-27	2005-03-31	Sb Pharmco Inc	Sales de fosfato de carvedilol y/o solvatos de las mismas, composiciones correspondientes y/o metodos de tratamiento.
SI21616A (sl) *	2003-09-02	2005-04-30	Krka, Tovarna Zdravil, D.D., Novo Mesto	Nove kristalne oblike karvedilola
EP1781611A1 (en) *	2005-06-09	2007-05-09	Teva Pharmaceutical Industries Ltd.	Crystalline forms of carvedilol and processes for their preparation
WO2008002683A2 (en) *	2006-06-28	2008-01-03	Teva Pharmaceutical Industries Ltd.	Polymorphous forms of carvedilol phosphate
US20090028935A1 (en) *	2006-12-01	2009-01-29	Kristin Arnold	Carvedilol forms, compositions, and methods of preparation thereof
US20080292695A1 (en) *	2006-12-01	2008-11-27	Kristin Arnold	Carvedilol forms, compositions, and methods of preparation thereof
US20080207726A1 (en) *	2007-02-26	2008-08-28	Santiago Ini	Process for the purification of carvedilol or its salts thereof
US20080249317A1 (en) *	2007-04-04	2008-10-09	Apotex Inc.	Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
TWI415604B (zh) *	2009-09-29	2013-11-21	Tsh Biopharm Corp Ltd	調控釋放卡菲蒂羅劑型
US20110229564A1 (en) *	2010-03-22	2011-09-22	Amneal Pharmaceuticals, L.L.C.	Pharmaceutical Compositions Of Carvedilol Salts And Process For Preparation Thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2815926A1 (de) *	1978-04-13	1979-10-18	Boehringer Mannheim Gmbh	Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) *	1983-05-26	1984-11-29	Boehringer Mannheim Gmbh, 6800 Mannheim	Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
GB9113802D0 (en) *	1991-06-26	1991-08-14	Smithkline Beecham Plc	Medicaments
US5393772A (en) *	1993-11-24	1995-02-28	Boehringer Mannheim Pharmaceuticals Corporation	Use of, and method of treatment using, hydroxycarbazole compounds for inhibition of smooth muscle migration and proliferation
EP0893440A1 (en) *	1997-07-22	1999-01-27	Roche Diagnostics GmbH	Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it
HU227441B1 (en) *	1997-11-24	2011-06-28	Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag	Process for producing carvedilol, enantiomers and salts thereof
US20010036959A1 (en) *	2000-04-03	2001-11-01	Gabel Rolf Dieter	Carvedilol-hydrophilic solutions
IL153688A0 (en) *	2000-06-28	2003-07-06	Teva Pharma	Carvedilol

2002
- 2002-09-18 WO PCT/EP2002/010451 patent/WO2003029214A1/en not_active Ceased
- 2002-09-18 DE DE60221683T patent/DE60221683T2/de not_active Expired - Fee Related
- 2002-09-18 AU AU2002338726A patent/AU2002338726B2/en not_active Ceased
- 2002-09-18 RU RU2004113209/04A patent/RU2308449C2/ru not_active IP Right Cessation
- 2002-09-18 EP EP02777139A patent/EP1432681B1/en not_active Expired - Lifetime
- 2002-09-18 JP JP2003532464A patent/JP2005507899A/ja active Pending
- 2002-09-18 BR BR0212927-2A patent/BR0212927A/pt not_active IP Right Cessation
- 2002-09-18 MX MXPA04002826A patent/MXPA04002826A/es active IP Right Grant
- 2002-09-18 KR KR1020047004578A patent/KR100752549B1/ko not_active Expired - Fee Related
- 2002-09-18 ES ES02777139T patent/ES2291503T3/es not_active Expired - Lifetime
- 2002-09-18 CA CA002460486A patent/CA2460486A1/en not_active Abandoned
- 2002-09-18 PL PL02370412A patent/PL370412A1/pl not_active Application Discontinuation
- 2002-09-18 CN CNB028187415A patent/CN1308307C/zh not_active Expired - Fee Related
- 2002-09-18 AT AT02777139T patent/ATE369339T1/de not_active IP Right Cessation
- 2002-09-24 PE PE2002000938A patent/PE20030448A1/es not_active Application Discontinuation
- 2002-09-25 PA PA20028555201A patent/PA8555201A1/es unknown
- 2002-09-26 US US10/255,290 patent/US20030119893A1/en not_active Abandoned
- 2002-09-27 GT GT200200198A patent/GT200200198A/es unknown
- 2002-09-27 AR ARP020103656A patent/AR036689A1/es not_active Application Discontinuation
- 2002-09-27 UY UY27461A patent/UY27461A1/es not_active Application Discontinuation
2004
- 2004-04-20 US US10/827,859 patent/US20040198812A1/en not_active Abandoned
2006
- 2006-01-05 US US11/325,754 patent/US20060148878A1/en not_active Abandoned

Also Published As

Publication number	Publication date
BR0212927A (pt)	2004-10-13
US20060148878A1 (en)	2006-07-06
DE60221683T2 (de)	2008-04-30
KR100752549B1 (ko)	2007-08-30
US20040198812A1 (en)	2004-10-07
RU2004113209A (ru)	2005-05-20
UY27461A1 (es)	2003-06-30
PA8555201A1 (es)	2003-12-10
AU2002338726B9 (en)	2003-04-14
KR20040047872A (ko)	2004-06-05
CN1558900A (zh)	2004-12-29
US20030119893A1 (en)	2003-06-26
WO2003029214A1 (en)	2003-04-10
EP1432681A1 (en)	2004-06-30
AU2002338726B2 (en)	2007-03-15
AR036689A1 (es)	2004-09-29
DE60221683D1 (en)	2007-09-20
EP1432681B1 (en)	2007-08-08
ATE369339T1 (de)	2007-08-15
JP2005507899A (ja)	2005-03-24
ES2291503T3 (es)	2008-03-01
CA2460486A1 (en)	2003-04-10
GT200200198A (es)	2003-06-19
CN1308307C (zh)	2007-04-04
RU2308449C2 (ru)	2007-10-20
PE20030448A1 (es)	2003-06-19
MXPA04002826A (es)	2004-07-02

Legal Events

Date	Code	Title	Description
2010-02-26	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)

Publication	Publication Date	Title
YU2200A (sh)	2002-03-18	Termodinamički stabilna modifikacija 1-(4-karbazoliloksi)-3-/2-(2-metoksifenoksi)etilamino/-2-propanola, postupak za njeno dobijanje i farmaceutske smeše koje je sadrže
NO20024891L (no)	2002-12-05	Farmasöytiske sammensetninger
BR9917007A (pt)	2001-10-30	Moduladores de ccr5
EA200000840A1 (ru)	2001-02-26	Антивирусные производные пиримидина
MY136767A (en)	2008-11-28	Formulations comprising an indolinone compound
AP9901534A0 (en)	1999-06-30	Pharmaceutical formulations.
AU2003291885A1 (en)	2004-06-30	Compounds and methods for the treatment or prevention of flavivirus infections
DE60330187D1 (de)	2009-12-31	Fluoralkoxy-substituierte 1, 3-dihydro-isoindolyl-verbindungen und ihre pharmazeutischen verwendungen
MXPA05001607A (es)	2005-09-20	Forma galenica para suministro de ingredientes activos dirigido al colon.
MXPA04002167A (es)	2004-06-29	Inhibidores de la 17 beta-hidroxiesteroide deshidrogenasa tipo 3 para el tratamiento de enfermedades androgeno-dependientes.
CY1107383T1 (el)	2012-12-19	Αναστολεις της φωσφολιπασης α2 του κυτοπλασμικου διαλυματος
DE69719755D1 (de)	2003-04-17	Polymorphe verbindungen
MXPA02012626A (es)	2003-04-25	Bis-arilsufonas.
MXPA03010761A (es)	2004-03-02	Combinaciones farmaceuticas.
MXPA04006041A (es)	2004-09-27	Antivirales de piridoquinoxalina.
BR0212927A (pt)	2004-10-13	Formas pseudopolimórficas de carvedilol
MXPA05008960A (es)	2005-11-04	Oxazolidinonas de indolona antibacteriales, intermedios para su preparacion y composiciones farmaceuticas que las contienen.
AU7616200A (en)	2001-04-30	Stable calcitriol solution for packaging in vials
MXPA04005809A (es)	2004-09-13	Inhibidores de proteinas quinasas.
AP2001002149A0 (en)	2001-06-30	Indole derivatives(Priority title)
AU2002211493A1 (en)	2002-05-15	Indole derivatives as pde5-inhibitors
AU2002248531A1 (en)	2002-09-24	Pyrazolopyriadine derivatives
BR9909260A (pt)	2000-11-21	Processo para o preparo de (r)-alfa-(2,3-dimetóxifenil)-1-[2-(4-fluoro-fenil)etil]-4-pi peridinametanol
PL390683A1 (pl)	2010-05-24	Zastosowanie pochodnych pirolu do wytwarzania leku
DE60212130D1 (en)	2006-07-20	Carvedilolpolymorph