PL3710457T3 - Inhibitory immunoproteasomu - Google Patents

Inhibitory immunoproteasomu

Info

Publication number
PL3710457T3
PL3710457T3 PL18812554.6T PL18812554T PL3710457T3 PL 3710457 T3 PL3710457 T3 PL 3710457T3 PL 18812554 T PL18812554 T PL 18812554T PL 3710457 T3 PL3710457 T3 PL 3710457T3
Authority
PL
Poland
Prior art keywords
immunoproteasome inhibitors
immunoproteasome
inhibitors
Prior art date
Application number
PL18812554.6T
Other languages
English (en)
Inventor
Yan Lou
Timothy Duncan Owens
Kenneth Albert Brameld
David Michael Goldstein
Original Assignee
Principia Biopharma Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Principia Biopharma Inc. filed Critical Principia Biopharma Inc.
Publication of PL3710457T3 publication Critical patent/PL3710457T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/025—Boronic and borinic acid compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/02—Boron compounds
    • C07F5/027—Organoboranes and organoborohydrides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/69—Boron compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PL18812554.6T 2017-11-16 2018-11-14 Inhibitory immunoproteasomu PL3710457T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201762587375P 2017-11-16 2017-11-16
PCT/US2018/061132 WO2019099576A1 (en) 2017-11-16 2018-11-14 Immunoproteasome inhibitors

Publications (1)

Publication Number Publication Date
PL3710457T3 true PL3710457T3 (pl) 2023-02-20

Family

ID=64572584

Family Applications (1)

Application Number Title Priority Date Filing Date
PL18812554.6T PL3710457T3 (pl) 2017-11-16 2018-11-14 Inhibitory immunoproteasomu

Country Status (18)

Country Link
US (1) US12024531B2 (pl)
EP (1) EP3710457B1 (pl)
JP (1) JP7333321B2 (pl)
KR (1) KR102647050B1 (pl)
CN (1) CN111491939B (pl)
AU (1) AU2018369787B2 (pl)
CA (1) CA3080958A1 (pl)
DK (1) DK3710457T3 (pl)
ES (1) ES2928787T3 (pl)
HR (1) HRP20221292T1 (pl)
HU (1) HUE060020T2 (pl)
LT (1) LT3710457T (pl)
MX (1) MX2020005036A (pl)
PL (1) PL3710457T3 (pl)
PT (1) PT3710457T (pl)
RS (1) RS63666B1 (pl)
SI (1) SI3710457T1 (pl)
WO (1) WO2019099576A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE054460T2 (hu) 2017-01-18 2021-09-28 Principia Biopharma Inc Immunproteaszóma-gátlók
WO2019099582A1 (en) 2017-11-16 2019-05-23 Principia Biopharma Inc. Immunoproteasome inhibitors

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4107288A (en) 1974-09-18 1978-08-15 Pharmaceutical Society Of Victoria Injectable compositions, nanoparticles useful therein, and process of manufacturing same
US4963655A (en) 1988-05-27 1990-10-16 Mayo Foundation For Medical Education And Research Boron analogs of amino acid/peptide protease inhibitors
US5145684A (en) 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
IL111175A0 (en) * 1993-10-07 1994-12-29 Du Pont Merck Pharma Electrophilic peptide analogs as inhibitors of trypsin-like serine proteases and pharmaceutical compositions containing them
US6083903A (en) * 1994-10-28 2000-07-04 Leukosite, Inc. Boronic ester and acid compounds, synthesis and uses
US7576206B2 (en) * 2003-08-14 2009-08-18 Cephalon, Inc. Proteasome inhibitors and methods of using the same
AU2005216970B2 (en) 2004-02-23 2011-07-07 Trustees Of Tufts College Inhibitors of dipeptidylpeptidase IV for regulating glucose metabolism
SG10201605152SA (en) 2011-12-22 2016-08-30 Ares Trading Sa Alpha-amino boronic acid derivatives, selective immunoproteasome inhibitors
NZ705040A (en) * 2012-07-20 2017-07-28 Cleave Biosciences Inc Fused pyrimidines as inhibitors of p97 complex
US10654843B2 (en) 2014-06-20 2020-05-19 Principia Biopharma Inc. LMP7 inhibitors
AU2015327345B9 (en) * 2014-10-01 2020-06-18 Merck Patent Gmbh Boronic acid derivatives
HUE054460T2 (hu) * 2017-01-18 2021-09-28 Principia Biopharma Inc Immunproteaszóma-gátlók
WO2019099582A1 (en) 2017-11-16 2019-05-23 Principia Biopharma Inc. Immunoproteasome inhibitors

Also Published As

Publication number Publication date
PT3710457T (pt) 2022-10-25
ES2928787T3 (es) 2022-11-22
US20230133165A1 (en) 2023-05-04
RS63666B1 (sr) 2022-11-30
US12024531B2 (en) 2024-07-02
CA3080958A1 (en) 2019-05-23
EP3710457A1 (en) 2020-09-23
CN111491939B (zh) 2023-12-26
KR20200090810A (ko) 2020-07-29
JP2021503467A (ja) 2021-02-12
SI3710457T1 (sl) 2023-02-28
DK3710457T3 (da) 2022-10-24
AU2018369787B2 (en) 2023-04-20
MX2020005036A (es) 2020-08-17
EP3710457B1 (en) 2022-08-03
AU2018369787A1 (en) 2020-05-14
LT3710457T (lt) 2022-11-10
HUE060020T2 (hu) 2023-01-28
KR102647050B1 (ko) 2024-03-14
JP7333321B2 (ja) 2023-08-24
HRP20221292T1 (hr) 2022-12-23
WO2019099576A1 (en) 2019-05-23
CN111491939A (zh) 2020-08-04

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