PL371217A1 - Inhibitory integryny alfaVbeta6 - Google Patents
Inhibitory integryny alfaVbeta6Info
- Publication number
- PL371217A1 PL371217A1 PL03371217A PL37121703A PL371217A1 PL 371217 A1 PL371217 A1 PL 371217A1 PL 03371217 A PL03371217 A PL 03371217A PL 37121703 A PL37121703 A PL 37121703A PL 371217 A1 PL371217 A1 PL 371217A1
- Authority
- PL
- Poland
- Prior art keywords
- integrin
- inhibitors
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title 1
- 108010004788 integrin alphavbeta6 Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Virology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Reproductive Health (AREA)
- Tropical Medicine & Parasitology (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10204789A DE10204789A1 (de) | 2002-02-06 | 2002-02-06 | Inhibitoren des Integrins alpha¶v¶beta6 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL371217A1 true PL371217A1 (pl) | 2005-06-13 |
Family
ID=27588391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL03371217A PL371217A1 (pl) | 2002-02-06 | 2003-01-15 | Inhibitory integryny alfaVbeta6 |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US7138417B2 (pl) |
| EP (1) | EP1472224B1 (pl) |
| JP (1) | JP4589628B2 (pl) |
| CN (1) | CN1628101A (pl) |
| AR (1) | AR038354A1 (pl) |
| AU (1) | AU2003208325B2 (pl) |
| CA (1) | CA2475930C (pl) |
| DE (1) | DE10204789A1 (pl) |
| ES (1) | ES2389300T3 (pl) |
| PL (1) | PL371217A1 (pl) |
| RU (1) | RU2004126944A (pl) |
| WO (1) | WO2003066594A2 (pl) |
| ZA (1) | ZA200407035B (pl) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10112771A1 (de) * | 2001-03-16 | 2002-09-26 | Merck Patent Gmbh | Inhibitoren des Integrins alpha¶v¶beta¶6¶ |
| WO2004052277A2 (en) * | 2002-12-05 | 2004-06-24 | Wisconsin Alumni Research Foundation | Anthrax antitoxins |
| KR20060109247A (ko) * | 2005-04-13 | 2006-10-19 | 엘지전자 주식회사 | 베이스 레이어 픽처를 이용하는 영상신호의 엔코딩/디코딩방법 및 장치 |
| US7838252B2 (en) * | 2005-02-17 | 2010-11-23 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for treating a subject having an anthrax toxin mediated condition |
| EP2730282A1 (en) * | 2007-11-08 | 2014-05-14 | The General Hospital Corporation | Methods and compositions for the treatment of proteinuric diseases |
| WO2012085081A1 (en) | 2010-12-22 | 2012-06-28 | Basf Se | Sulfoximinamide compounds for combating invertebrate pests ii |
| WO2018106945A1 (en) | 2016-12-07 | 2018-06-14 | Progenity Inc. | Gastrointestinal tract detection methods, devices and systems |
| US20200253506A1 (en) | 2016-12-14 | 2020-08-13 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| MA52117A (fr) | 2017-02-28 | 2022-04-06 | Morphic Therapeutic Inc | Inhibiteurs de l'intégrine (alpha-v) (bêta-6) |
| MX394210B (es) | 2017-02-28 | 2025-03-04 | Morphic Therapeutic Inc | INHIBIDORES DE INTEGRINA AVß6. |
| US20230033021A1 (en) | 2018-06-20 | 2023-02-02 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with an integrin inhibitor |
| WO2020047208A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | Inhibitors of (alpha-v)(beta-6) integrin |
| WO2020047239A1 (en) | 2018-08-29 | 2020-03-05 | Morphic Therapeutic, Inc. | INHIBITING αV β6 INTEGRIN |
| SI3844162T1 (sl) | 2018-08-29 | 2025-06-30 | Morphic Therapeutic, Inc. | Zaviralci integrina alfa v beta6 |
| EP3883635A1 (en) | 2018-11-19 | 2021-09-29 | Progenity, Inc. | Methods and devices for treating a disease with biotherapeutics |
| CN115666704B (zh) | 2019-12-13 | 2025-09-26 | 比特比德科有限责任公司 | 用于将治疗剂递送至胃肠道的可摄取装置 |
| CN115989235A (zh) * | 2020-05-07 | 2023-04-18 | 普利安特治疗公司 | 使用氨基酸化合物治疗呼吸系统疾病的方法 |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3087828A (en) | 1961-06-28 | 1963-04-30 | Du Pont | Nacreous pigment compositions |
| US3658552A (en) | 1969-05-22 | 1972-04-25 | Gen Foods Corp | Clouding agent |
| BE759469A (fr) | 1969-11-29 | 1971-05-26 | Merck Patent Gmbh | Pigment a brillant nacre et leurs procedes de |
| US3875890A (en) | 1973-02-06 | 1975-04-08 | Cava Carl | Side warning device for cycles |
| DE2429762C2 (de) | 1974-06-21 | 1984-08-30 | Merck Patent Gmbh, 6100 Darmstadt | Farbstoffhaltige Glanzpigmente |
| US4968351A (en) | 1988-11-02 | 1990-11-06 | The Mearl Corporation | Nacreous pigments colored by adsorbed dyes |
| GB2257433A (en) | 1991-07-12 | 1993-01-13 | Bipin Chandra Muljibhai Patel | Dental material usable as e.g. fissure sealant |
| GB9115154D0 (en) | 1991-07-12 | 1991-08-28 | Patel Bipin C M | Sol-gel composition for producing glassy coatings |
| JP2835796B2 (ja) | 1992-02-06 | 1998-12-14 | メルク・ジヤパン株式会社 | 新規な薄片状顔料 |
| DE4212304A1 (de) * | 1992-04-13 | 1993-10-14 | Cassella Ag | Asparaginsäurederivate, ihre Herstellung und Verwendung |
| DE4215367A1 (de) | 1992-05-08 | 1993-11-11 | Gerhard Ruth Gmbh & Co Kg | Farbpigmentpartikel für eine Lebensmittelfarbe |
| US6306840B1 (en) * | 1995-01-23 | 2001-10-23 | Biogen, Inc. | Cell adhesion inhibitors |
| FR2745493B1 (fr) | 1996-03-01 | 1998-04-24 | Oreal | Composition anhydre sous forme de poudre et utilisation d'un ester comme liant de poudres |
| DE19618564A1 (de) | 1996-05-09 | 1997-11-13 | Merck Patent Gmbh | Plättchenförmiges Titandioxidpigment |
| US5885342A (en) | 1997-05-09 | 1999-03-23 | Engelhard Corporation | Blended nacreous pigments, colorants and adjuvants |
| GB9723789D0 (en) * | 1997-11-12 | 1998-01-07 | Zeneca Ltd | Chemical compounds |
| US6139615A (en) | 1998-02-27 | 2000-10-31 | Engelhard Corporation | Pearlescent pigments containing ferrites |
| KR20010042614A (ko) * | 1998-04-10 | 2001-05-25 | 윌리암스 로저 에이 | 비트로넥틴 길항제로서 복소환식 글리실 베타-알라닌 유도체 |
| PL350057A1 (en) * | 1999-02-20 | 2002-11-04 | Merck Patent Gmbh | β-ALANINE DERIVATIVES |
| US6165260A (en) | 1999-03-30 | 2000-12-26 | Engelhard Corporation | Pearlescent pigments exhibiting color travel |
| WO2000066618A1 (de) * | 1999-04-28 | 2000-11-09 | Basf Aktiengesellschaft | Integrinrezeptorantagonisten |
| US6471762B1 (en) | 2000-08-23 | 2002-10-29 | Engelhard Corp. | Bonded metal-hydroxide-organic composite polymer films on lamellar pigments |
| DE10063173A1 (de) | 2000-12-18 | 2002-06-20 | Merck Patent Gmbh | Harnstoff- und Urethanderivate |
-
2002
- 2002-02-06 DE DE10204789A patent/DE10204789A1/de not_active Withdrawn
-
2003
- 2003-01-15 CA CA2475930A patent/CA2475930C/en not_active Expired - Fee Related
- 2003-01-15 WO PCT/EP2003/000327 patent/WO2003066594A2/de not_active Ceased
- 2003-01-15 US US10/503,616 patent/US7138417B2/en not_active Expired - Fee Related
- 2003-01-15 PL PL03371217A patent/PL371217A1/pl unknown
- 2003-01-15 CN CNA038034476A patent/CN1628101A/zh active Pending
- 2003-01-15 RU RU2004126944/04A patent/RU2004126944A/ru not_active Application Discontinuation
- 2003-01-15 EP EP03706358A patent/EP1472224B1/de not_active Expired - Lifetime
- 2003-01-15 JP JP2003565968A patent/JP4589628B2/ja not_active Expired - Fee Related
- 2003-01-15 ES ES03706358T patent/ES2389300T3/es not_active Expired - Lifetime
- 2003-01-15 AU AU2003208325A patent/AU2003208325B2/en not_active Ceased
- 2003-02-05 AR ARP030100360A patent/AR038354A1/es unknown
-
2004
- 2004-10-02 ZA ZA200407035A patent/ZA200407035B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2475930A1 (en) | 2003-08-14 |
| RU2004126944A (ru) | 2006-02-10 |
| EP1472224A2 (de) | 2004-11-03 |
| ES2389300T3 (es) | 2012-10-25 |
| WO2003066594A3 (de) | 2003-11-27 |
| JP4589628B2 (ja) | 2010-12-01 |
| JP2005519929A (ja) | 2005-07-07 |
| AU2003208325B2 (en) | 2009-04-30 |
| CN1628101A (zh) | 2005-06-15 |
| AR038354A1 (es) | 2005-01-12 |
| CA2475930C (en) | 2011-09-27 |
| WO2003066594A2 (de) | 2003-08-14 |
| US20050153902A1 (en) | 2005-07-14 |
| ZA200407035B (en) | 2006-06-28 |
| US7138417B2 (en) | 2006-11-21 |
| EP1472224B1 (de) | 2012-07-11 |
| DE10204789A1 (de) | 2003-08-14 |
| AU2003208325A1 (en) | 2003-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| DISC | Decisions on discontinuance of the proceedings (taken after the publication of the particulars of the applications) |