PL371681A1 - Związki przydatne do wytwarzania pochodnych kamptotecyny - Google Patents

Związki przydatne do wytwarzania pochodnych kamptotecyny

Info

Publication number
PL371681A1
PL371681A1 PL03371681A PL37168103A PL371681A1 PL 371681 A1 PL371681 A1 PL 371681A1 PL 03371681 A PL03371681 A PL 03371681A PL 37168103 A PL37168103 A PL 37168103A PL 371681 A1 PL371681 A1 PL 371681A1
Authority
PL
Poland
Prior art keywords
compounds useful
camptothecin derivatives
preparing camptothecin
preparing
derivatives
Prior art date
Application number
PL03371681A
Other languages
English (en)
Inventor
Kevin E. Henegar
Original Assignee
Pharmacia Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Corporation filed Critical Pharmacia Corporation
Publication of PL371681A1 publication Critical patent/PL371681A1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
PL03371681A 2002-04-17 2003-04-16 Związki przydatne do wytwarzania pochodnych kamptotecyny PL371681A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37372702P 2002-04-17 2002-04-17

Publications (1)

Publication Number Publication Date
PL371681A1 true PL371681A1 (pl) 2005-06-27

Family

ID=29251068

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03371681A PL371681A1 (pl) 2002-04-17 2003-04-16 Związki przydatne do wytwarzania pochodnych kamptotecyny

Country Status (15)

Country Link
US (1) US6723729B2 (pl)
EP (1) EP1501799A1 (pl)
JP (1) JP3839813B2 (pl)
KR (1) KR20050009293A (pl)
CN (1) CN1646491A (pl)
AU (1) AU2003224973A1 (pl)
BR (1) BR0309284A (pl)
CA (1) CA2482712A1 (pl)
IL (1) IL164311A0 (pl)
MX (1) MXPA04009426A (pl)
PL (1) PL371681A1 (pl)
RS (1) RS91304A (pl)
RU (1) RU2287527C2 (pl)
WO (1) WO2003089413A1 (pl)
ZA (1) ZA200407821B (pl)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050197355A1 (en) * 2004-03-02 2005-09-08 Henegar Kevin E. Compounds useful in preparing camptothecin derivatives
WO2006016203A1 (en) * 2004-08-09 2006-02-16 Shilpa Medicare Limited An improved process for the preparation of irinotecan hydrochloride trihydrate
ATE446299T1 (de) * 2005-02-07 2009-11-15 Fermion Oy Verfahren zur herstellung von 7-ethyl-10- hydroxycamptothecin
EP1928883B1 (en) * 2005-02-08 2013-10-30 Fermion Oy Process for the preparation of irinotecan hydrochloride
ES2430375T3 (es) * 2005-02-08 2013-11-20 Fermion Oy Procedimiento para la producción de cloruro de [1,4']bipiperidinil-1'-carbonilo o su clorhidrato
TWI375678B (en) * 2005-06-09 2012-11-01 Yakult Honsha Kk A method of preparation of a tricyclic ketone
WO2008035377A2 (en) * 2006-09-18 2008-03-27 Shilpa Medicare Ltd. Novel intermediates for the preparation of camptothecin analogues
US8546573B2 (en) * 2009-11-18 2013-10-01 Cadila Healthcare Limited Process for the preparation of 7-ethyl-10-[4-(1-piperidino)-1-piperdino] carbonyloxy-camptothecin hydrochloride trihydrate
WO2012032531A1 (en) * 2010-09-06 2012-03-15 Avra Laboratories Pvt. Ltd. Process for the manufacture of irinotecan hydrochloride by total synthesis
EP2881396A1 (en) * 2013-12-03 2015-06-10 Synbias Pharma AG Method for the synthesis of irinotecan

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3682874D1 (de) * 1985-10-21 1992-01-23 Daiichi Seiyaku Co Pyranoindolizinderivate und verfahren zu ihrer herstellung.
US5952354A (en) * 1993-07-21 1999-09-14 American Home Products Corporation Tris carbamic acid esters: inhibitors of cholesterol absorption
TW438775B (en) 1995-04-07 2001-06-07 Pharmacia & Upjohn Co Llc Novel intermediates and process for the manufacture of camptothecin derivatives (CPT-11) and related compounds

Also Published As

Publication number Publication date
AU2003224973A1 (en) 2003-11-03
JP3839813B2 (ja) 2006-11-01
RU2287527C2 (ru) 2006-11-20
RU2004130493A (ru) 2005-04-20
RS91304A (sr) 2007-02-05
MXPA04009426A (es) 2005-01-25
ZA200407821B (en) 2005-06-29
US6723729B2 (en) 2004-04-20
WO2003089413A1 (en) 2003-10-30
KR20050009293A (ko) 2005-01-24
CN1646491A (zh) 2005-07-27
JP2005523324A (ja) 2005-08-04
US20040048832A1 (en) 2004-03-11
EP1501799A1 (en) 2005-02-02
IL164311A0 (en) 2005-12-18
CA2482712A1 (en) 2003-10-30
BR0309284A (pt) 2005-02-22

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Legal Events

Date Code Title Description
REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)