PL3721880T3 - Kompozycja i sposób naprawy i regeneracji mięśni - Google Patents

Kompozycja i sposób naprawy i regeneracji mięśni

Info

Publication number
PL3721880T3
PL3721880T3 PL20171639T PL20171639T PL3721880T3 PL 3721880 T3 PL3721880 T3 PL 3721880T3 PL 20171639 T PL20171639 T PL 20171639T PL 20171639 T PL20171639 T PL 20171639T PL 3721880 T3 PL3721880 T3 PL 3721880T3
Authority
PL
Poland
Prior art keywords
regeneration
composition
muscle repair
muscle
repair
Prior art date
Application number
PL20171639T
Other languages
English (en)
Inventor
Masahiro Iwamoto
Maurizio Pacifici
Original Assignee
Thomas Jefferson University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45773490&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL3721880(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Thomas Jefferson University filed Critical Thomas Jefferson University
Publication of PL3721880T3 publication Critical patent/PL3721880T3/pl

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
PL20171639T 2010-09-01 2011-08-31 Kompozycja i sposób naprawy i regeneracji mięśni PL3721880T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37899610P 2010-09-01 2010-09-01
EP20171639.6A EP3721880B1 (en) 2010-09-01 2011-08-31 Composition and method for muscle repair and regeneration
EP11822537.4A EP2613776B1 (en) 2010-09-01 2011-08-31 Composition and method for muscle repair and regeneration
PCT/US2011/049905 WO2012030919A2 (en) 2010-09-01 2011-08-31 Composition and method for muscle repair and regeneration

Publications (1)

Publication Number Publication Date
PL3721880T3 true PL3721880T3 (pl) 2022-05-23

Family

ID=45773490

Family Applications (2)

Application Number Title Priority Date Filing Date
PL20171639T PL3721880T3 (pl) 2010-09-01 2011-08-31 Kompozycja i sposób naprawy i regeneracji mięśni
PL11822537T PL2613776T3 (pl) 2010-09-01 2011-08-31 Kompozycja oraz sposób naprawy i regeneracji mięśni

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL11822537T PL2613776T3 (pl) 2010-09-01 2011-08-31 Kompozycja oraz sposób naprawy i regeneracji mięśni

Country Status (20)

Country Link
US (6) US9789074B2 (pl)
EP (3) EP2613776B1 (pl)
JP (1) JP5986570B2 (pl)
CN (2) CN103200937B (pl)
AU (1) AU2011296080B2 (pl)
BR (1) BR112013004685B1 (pl)
CA (1) CA2809374C (pl)
CL (1) CL2013000580A1 (pl)
CO (1) CO6680694A2 (pl)
DK (2) DK2613776T3 (pl)
EA (1) EA026251B1 (pl)
ES (3) ES2912593T3 (pl)
HU (2) HUE051664T2 (pl)
IL (1) IL224973B (pl)
MX (2) MX361414B (pl)
NZ (1) NZ607547A (pl)
PL (2) PL3721880T3 (pl)
PT (1) PT2613776T (pl)
WO (1) WO2012030919A2 (pl)
ZA (1) ZA201301536B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUE051664T2 (hu) 2010-09-01 2021-03-29 Univ Jefferson Összetétel és módszer az izomjavításra és a regenerációra
US11026952B2 (en) 2011-06-16 2021-06-08 President And Fellows Of Harvard College Small molecules for mouse satellite cell proliferation
US9782417B2 (en) 2011-06-16 2017-10-10 Presidents And Fellows Of Harvard College Methods of increasing satellite cell proliferation with kinase inhibitors
US11963964B2 (en) 2011-06-16 2024-04-23 President And Fellows Of Harvard College Small molecules for mouse satellite cell proliferation
SG10201704687YA (en) * 2012-11-08 2017-07-28 Univ Yamaguchi Therapeutic agent for keratoconjunctive disorders
US9375439B2 (en) 2013-01-09 2016-06-28 International Stem Cell Corporation Small molecules that promote skin regeneration
BR112015029114B1 (pt) 2013-05-22 2020-11-24 Yamaguchi University composição
EP3152190B1 (en) 2014-06-04 2024-07-31 Haro Pharmaceutical Inc. 18-20 member bi-polycyclic compounds
US9784665B1 (en) * 2014-12-29 2017-10-10 Flagship Biosciences, Inc. Methods for quantitative assessment of muscle fibers in muscular dystrophy
HK1253090A1 (zh) * 2015-05-06 2019-06-06 南加利福尼亚大学 治疗高血压和脂质紊乱的禁食模仿和加强膳食
EP3091084A1 (en) * 2015-05-08 2016-11-09 Université Catholique De Louvain Methods for assessing the purity of a mesenchymal stem cells preparation
CA3016308A1 (en) * 2016-02-01 2017-08-10 President And Fellows Of Harvard College Small molecules for mouse satellite cell proliferation
WO2017210792A1 (en) 2016-06-08 2017-12-14 Clementia Pharmaceuticals Inc. Methods for treating heterotopic ossification
US10980778B2 (en) 2016-11-16 2021-04-20 Clementia Pharmaceuticals Inc. Methods for treating multiple osteochondroma (MO)
CA3019069A1 (en) * 2018-04-02 2019-10-02 Hubit Genomix, Inc. Prophylactic and/or therapeutic drug for diabetic nephropathy
US11135236B2 (en) * 2018-04-10 2021-10-05 Northwestern University Retinoic acid receptor gamma agonists to attenuate anthracycline-induced cardiotoxicity
GB201907647D0 (en) * 2019-05-30 2019-07-17 King S College London Therapeutic methods
FR3112684B1 (fr) * 2020-07-24 2022-08-12 Univ Grenoble Alpes Composés pour le traitement de l’hémophilie
CN116891497B (zh) * 2022-04-02 2025-12-16 上海旭成医药科技有限公司 视黄酸受体激动剂、其制备方法、中间体、药物组合物和应用
WO2023241717A1 (zh) * 2022-06-16 2023-12-21 中国科学院动物研究所 促进哺乳动物器官再生修复的物质及其应用

Family Cites Families (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3270960A (en) 1964-09-11 1966-09-06 Sperry Rand Corp Fluid sensor
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
EP0139676B1 (en) 1983-02-04 1992-11-25 Cytoclonal Pharmaceutics Inc. Production and characterization of hybridoma antibodies directed specifically against common determinant(s) present among closely related, but distinct proteins
GB2148299B (en) 1983-09-01 1988-01-06 Hybritech Inc Antibody compositions of therapeutic agents having an extended serum half-life
JPS6253981A (ja) 1985-09-02 1987-03-09 Koichi Shiyudo 新規安息香酸誘導体
KR0139216B1 (ko) 1988-04-11 1998-05-01 제임스 엠. 캐내지 레티노이드 유사활성을 갖는 페놀 또는 벤조산의 테트랄린 에스테르
CA2129773C (en) 1993-09-02 2007-05-01 Michael Klaus Aromatic carboxylic acid derivatives
US5408002A (en) 1993-09-09 1995-04-18 Minnesota Mining And Manufacturing Company Azlactone-functional polymer blends, articles produced therefrom and methods for preparing both
US5498795A (en) 1994-12-29 1996-03-12 Allergan, Inc. Acetylenes disubstituted with hydroxyaryl and aryl or heteroaryl groups having retinoid-like biological activity
US5843780A (en) 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
US5807900A (en) 1995-03-31 1998-09-15 Hoffmann-La Roche, Inc. Method for identifying compounds having increased activity for the repair of skin photodamage
US5624957A (en) 1995-06-06 1997-04-29 Bristol-Myers Squibb Company Rary-specific retinobenzoic acid derivatives
FR2739557B1 (fr) * 1995-10-09 1997-11-14 Cird Galderma Utilisation d'un ligand agoniste specifique rar-gamma
FR2739777B1 (fr) * 1995-10-11 1997-11-14 Cird Galderma Ligand antagoniste rar-gamma ou agoniste rar-alpha en tant qu'inhibiteur d'apoptose
US5726191A (en) 1995-11-16 1998-03-10 Hoffmann-La Roche Inc. Aromatic carboxylic acid esters
US5994619A (en) 1996-04-01 1999-11-30 University Of Massachusetts, A Public Institution Of Higher Education Of The Commonwealth Of Massachusetts, As Represented By Its Amherst Campus Production of chimeric bovine or porcine animals using cultured inner cell mass cells
FR2747041B1 (fr) 1996-04-05 1998-05-22 Cird Galderma Utilisation de derives benzonaphtaleniques pour la fabrication de medicaments destines au traitement des neuropathies
US5945577A (en) 1997-01-10 1999-08-31 University Of Massachusetts As Represented By Its Amherst Campus Cloning using donor nuclei from proliferating somatic cells
US5919970A (en) 1997-04-24 1999-07-06 Allergan Sales, Inc. Substituted diaryl or diheteroaryl methanes, ethers and amines having retinoid agonist, antagonist or inverse agonist type biological activity
WO1998051317A1 (en) * 1997-05-13 1998-11-19 Osiris Therapeutics, Inc. Osteoarthritis cartilage regeneration using human mesenchymal stem cells
US7514074B2 (en) * 1997-07-14 2009-04-07 Osiris Therapeutics, Inc. Cardiac muscle regeneration using mesenchymal stem cells
ES2292245T3 (es) 1998-05-29 2008-03-01 Osiris Therapeutics, Inc. Celulas madre mesenquimaticas cd45+ y/o fibroblasto+humanas.
JP2002526445A (ja) 1998-09-24 2002-08-20 ブリストルーマイヤーズ スクイブ カンパニー RARγ−特異的作用薬の活性エナンチオマー
JO2178B1 (en) 1999-10-19 2003-04-23 اف . هوفمان لاروش ايه جي Treatment of invasive diseases, using selected anti-PAR materials
US6313168B1 (en) 1999-12-15 2001-11-06 Allergan Sales, Inc. Use of retinoid receptor antagonists in the treatment of cartilage and bone pathologies
US20030114482A1 (en) 1999-12-15 2003-06-19 Maurizio Pacifici Use of retinoid receptor antagonists or agonists in the treatment of cartilage and bone pathologies
CA2402413A1 (en) 2000-03-14 2001-09-20 The University Of Western Ontario Compositions and methods for affecting osteogenesis
ATE328067T1 (de) 2000-04-28 2006-06-15 Childrens Medical Center Isolierung von mesenchymalen stammzellen und deren verwendung
DK1324970T3 (da) 2000-10-02 2009-01-05 Hoffmann La Roche Retinoider til behandling af emfysem
US7087726B2 (en) 2001-02-22 2006-08-08 Genentech, Inc. Anti-interferon-α antibodies
MXPA04002305A (es) 2001-09-18 2004-06-29 Hoffmann La Roche Agonistas ii de retinoides de urea sustituida.
BR0212583A (pt) 2001-09-18 2004-10-13 Hoffmann La Roche Agonistas i para retinóides de alquil uréia
AUPR892501A0 (en) * 2001-11-16 2001-12-13 Peter Maccallum Cancer Institute, The Method of enhancing self renewal of stem cells and uses thereof
US7592174B2 (en) 2002-05-31 2009-09-22 The Board Of Trustees Of The Leland Stanford Junior University Isolation of mesenchymal stem cells
CN1656065A (zh) * 2002-06-04 2005-08-17 盖尔德马研究及发展公司 作为rar受体抑制剂的配体
JP2005537253A (ja) * 2002-07-03 2005-12-08 フォンダッチォーネ・セントロ・サン・ラファエル・デル・モンテ・タボール 組織損傷の治療におけるおよび/または組織修復を促進するためのhmgb1の使用
AU2003242976A1 (en) 2002-07-16 2004-02-02 Yissum Research Development Company Of The Hebrew University Of Jerusalem Methods of implanting mesenchymal stem cells for tissue repair and formation
US20050101581A1 (en) 2002-08-28 2005-05-12 Reading Christopher L. Therapeutic treatment methods 2
KR101151477B1 (ko) 2003-12-10 2012-06-22 메다렉스, 인코포레이티드 인터페론 알파 항체 및 그의 용도
JP2005206544A (ja) 2004-01-23 2005-08-04 Yasuyoshi Uchida 筋肉再生剤
AU2005240078A1 (en) 2004-04-30 2005-11-17 Allergan, Inc. Retinoid-containing sustained release intraocular drug delivery systems and related methods of manufacturing
WO2005115304A2 (en) 2004-05-24 2005-12-08 Ab Science Use of c-kit inhibitors for treating fibrodysplasia
US7345931B2 (en) 2005-08-01 2008-03-18 Infineon Technologies Ag Maintaining internal voltages of an integrated circuit in response to a clocked standby mode
FR2894959B1 (fr) 2005-12-15 2008-02-29 Galderma Res & Dev Derives biphenyliques agonistes selectifs du recepteur rar-gamma
FR2894960B1 (fr) 2005-12-15 2008-02-29 Galderma Res & Dev Derives biphenyliques agonistes selectifs du recepteurs rar-gamma
EP1999626A4 (en) 2006-01-26 2009-11-25 Combinatorx Inc METHODS, COMPOSITIONS AND NEEDS FOR TREATING MUSCULOSKELETAL DISORDERS AND SYMPTOMS ASSOCIATED THEREWITH
US20090117203A1 (en) * 2006-03-23 2009-05-07 Tmrc Co., Ltd. Kit for cancer treatment and pharmaceutical composition for cancer treatment
WO2007113122A1 (en) 2006-03-31 2007-10-11 F. Hoffmann-La Roche Ag Process for preparing retinoid compounds
JP2009537540A (ja) 2006-05-16 2009-10-29 ビテ ファーマシューティカルズ, インコーポレイテッド 化学療法および/または放射線療法の副作用を処置するためのrarアンタゴニストまたはrarインバースアゴニストの使用
US9119777B2 (en) 2008-05-30 2015-09-01 Microdose Therapeutx, Inc. Methods and compositions for administration of oxybutynin
JP5638961B2 (ja) 2008-03-13 2014-12-10 ザ ジェネラル ホスピタル コーポレイション Bmpシグナル伝達経路のインヒビター
EP2379174A4 (en) 2008-12-18 2012-11-14 Astrazeneca Ab PHARMACEUTICAL PRODUCT USING A P38 KINASE INHIBITOR AND A SECOND ACTIVE SUBSTANCE
WO2010088735A1 (en) 2009-02-05 2010-08-12 Regenertech Pty Ltd Method of producing progenitor cells from differentiated cells
WO2011011513A1 (en) 2009-07-21 2011-01-27 University Of Washington Through Its Center For Commercialization Inhibition of pathological bone formation
UA50725U (ru) * 2009-12-01 2010-06-25 Институт Нейрохирургии Им. Акад. А.П. Ромоданова Амн Украины Способ лечения больных с прогрессирующей мышечной дистрофией трансплантацией миобластов эмбриона человека
HUE051664T2 (hu) 2010-09-01 2021-03-29 Univ Jefferson Összetétel és módszer az izomjavításra és a regenerációra
WO2012125724A1 (en) 2011-03-14 2012-09-20 Beth Israel Deaconess Medical Center Methods and compositions for the treatment of proliferative disorders
US9464065B2 (en) 2011-03-24 2016-10-11 The Scripps Research Institute Compounds and methods for inducing chondrogenesis
WO2013006372A1 (en) 2011-07-01 2013-01-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Method of treating pathologic heterotopic ossification
WO2013126608A1 (en) 2012-02-22 2013-08-29 Sanford-Burnham Medical Research Institute Sulfonamide compounds and uses as tnap inhibitors
DK2900238T3 (en) 2012-09-28 2018-03-12 Univ Vanderbilt CONDENSED HETEROCYCLIC COMPOUNDS AS SELECTIVE BMP INHIBITORS
EP2964651A4 (en) 2013-03-04 2016-11-30 Brigham & Womens Hospital BMP HEMMER AND METHOD OF USE THEREOF
US9682983B2 (en) 2013-03-14 2017-06-20 The Brigham And Women's Hospital, Inc. BMP inhibitors and methods of use thereof
BR112015029114B1 (pt) 2013-05-22 2020-11-24 Yamaguchi University composição
WO2016054406A1 (en) 2014-10-01 2016-04-07 The Brigham And Women's Hospital, Inc. Compositions and methods for inhibiting bmp
US20180311356A1 (en) 2015-10-19 2018-11-01 The Children's Medical Center Corporation Method to inhibit endothelial-to-mesenchymal transition
EP3393474B1 (en) 2015-12-24 2023-07-19 The Regents of The University of Michigan Method of treating heterotopic ossification
WO2017210792A1 (en) 2016-06-08 2017-12-14 Clementia Pharmaceuticals Inc. Methods for treating heterotopic ossification
JP6630255B2 (ja) 2016-09-30 2020-01-15 株式会社沖データ 画像形成装置及び通信システム

Also Published As

Publication number Publication date
CA2809374A1 (en) 2012-03-08
WO2012030919A2 (en) 2012-03-08
MX361414B (es) 2018-12-05
EP4066826B1 (en) 2024-03-06
US9314439B2 (en) 2016-04-19
US20180000762A1 (en) 2018-01-04
US20140363402A1 (en) 2014-12-11
CL2013000580A1 (es) 2013-07-12
US10292954B2 (en) 2019-05-21
CA2809374C (en) 2021-02-23
EP2613776B1 (en) 2020-07-29
DK2613776T3 (da) 2020-10-19
US11433039B2 (en) 2022-09-06
HUE059024T2 (hu) 2022-10-28
EP4066826A1 (en) 2022-10-05
DK3721880T3 (da) 2022-05-09
IL224973B (en) 2018-06-28
HUE051664T2 (hu) 2021-03-29
CO6680694A2 (es) 2013-05-31
ES2975123T3 (es) 2024-07-03
CN103200937B (zh) 2020-07-03
US12023312B2 (en) 2024-07-02
NZ607547A (en) 2015-06-26
JP2013536855A (ja) 2013-09-26
MX2018015032A (es) 2021-12-08
ES2912593T3 (es) 2022-05-26
WO2012030919A3 (en) 2012-07-05
US20140303223A1 (en) 2014-10-09
PL2613776T3 (pl) 2021-01-11
JP5986570B2 (ja) 2016-09-06
EP3721880A1 (en) 2020-10-14
BR112013004685B1 (pt) 2021-09-21
EP2613776A2 (en) 2013-07-17
US20250108022A1 (en) 2025-04-03
EP4066826C0 (en) 2024-03-06
EP2613776A4 (en) 2014-03-12
US20200069620A1 (en) 2020-03-05
MX2013002275A (es) 2013-05-22
CN111773213B (zh) 2023-02-24
EA201370051A1 (ru) 2014-03-31
CN103200937A (zh) 2013-07-10
EA026251B1 (ru) 2017-03-31
US20230201146A1 (en) 2023-06-29
AU2011296080B2 (en) 2014-12-04
AU2011296080A1 (en) 2013-03-14
CN111773213A (zh) 2020-10-16
PT2613776T (pt) 2020-10-21
EP3721880B1 (en) 2022-02-02
US9789074B2 (en) 2017-10-17
BR112013004685A2 (pt) 2019-04-24
ZA201301536B (en) 2015-06-24
ES2823234T3 (es) 2021-05-06

Similar Documents

Publication Publication Date Title
PL3721880T3 (pl) Kompozycja i sposób naprawy i regeneracji mięśni
ME03766B (me) Određeni amino-pirimidini, njihove kompozicije, i metode njihove upotrebe
EP2736974A4 (en) POLYMER COMPOSITIONS AND METHODS
IL223118A (en) Medicament inhaler and method for its assembly
EP2579816A4 (en) Implant components and methods
BR112013010725A2 (pt) método, e, composição
BR112014010450A2 (pt) composição e método
PL2734049T3 (pl) Kompozycje probiotyczne i sposoby
EP3797746C0 (en) COMPOSITE STRUCTURE AND METHOD FOR ITS MANUFACTURE
PL2841390T3 (pl) Stabilne wymiarowo kompozycje geopolimerów i metoda
BR112012027159A2 (pt) estrutura e método
ME02952B (me) Wnt antagonisti i metode tretiranja
BR112015002365A2 (pt) composição de borracha natural e método de produção de uma composição de borracha natural
EP2744519A4 (en) COMPOSITIONS AND METHODS FOR DERMAL REJUVENATION
BR112014008471A2 (pt) método de cimentação e composição de escória
PL2533761T3 (pl) Sposoby i kompozycje do wytwarzania aerozoli
BR112013007298A2 (pt) método para produzir composição de borracha
DK2661274T3 (da) Sammensætninger og fremgangsmåder med aloepolysaccharider
PL3400958T3 (pl) Kompozycje i metody leczenia celiakii
DE112011102437B8 (de) Klemmenverbindungsstruktur und Verfahren zum Herstellen derselben
FI20105423L (fi) Pinnoitusmenetelmä ja -laitteisto
BR112012029669A2 (pt) composição e método
EP2589489A4 (en) SHRINKABLE FILM AND METHOD FOR MANUFACTURING THE SAME
BR112014010860A2 (pt) composição e método
BR112014007779A2 (pt) método e composição