PL373247A1 - Sposób leczenia nowotworów drogą podawania tegafuru, uracylu, kwasu folinowego i cyklofosfoamidu - Google Patents

Sposób leczenia nowotworów drogą podawania tegafuru, uracylu, kwasu folinowego i cyklofosfoamidu

Info

Publication number: PL373247A1
Authority: PL; Poland
Prior art keywords: tegafur; cyclophosphamide; uracil; administration; folinic acid
Prior art date: 2001-04-26

Application number

PL02373247A

Other languages

English (en)

Inventor

Eric Winer

Craig Bunnell

Jody Ressler-Tatro

Terry Dugan

Original Assignee

Bristol-Myers Squibb Company

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-04-26

Filing date

2002-04-22

Publication date

2005-08-22

2002-04-22 Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company

2005-08-22 Publication of PL373247A1 publication Critical patent/PL373247A1/pl

Links

ISAKRJDGNUQOIC-UHFFFAOYSA-N Uracil Chemical compound O=C1C=CNC(=O)N1 ISAKRJDGNUQOIC-UHFFFAOYSA-N 0.000 title 2
VVIAGPKUTFNRDU-UHFFFAOYSA-N 6S-folinic acid Natural products C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-UHFFFAOYSA-N 0.000 title 1
CMSMOCZEIVJLDB-UHFFFAOYSA-N Cyclophosphamide Chemical compound ClCCN(CCCl)P1(=O)NCCCO1 CMSMOCZEIVJLDB-UHFFFAOYSA-N 0.000 title 1
MPJKWIXIYCLVCU-UHFFFAOYSA-N Folinic acid Natural products NC1=NC2=C(N(C=O)C(CNc3ccc(cc3)C(=O)NC(CCC(=O)O)CC(=O)O)CN2)C(=O)N1 MPJKWIXIYCLVCU-UHFFFAOYSA-N 0.000 title 1
206010028980 Neoplasm Diseases 0.000 title 1
229960004397 cyclophosphamide Drugs 0.000 title 1
VVIAGPKUTFNRDU-ABLWVSNPSA-N folinic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2N(C=O)C1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 VVIAGPKUTFNRDU-ABLWVSNPSA-N 0.000 title 1
235000008191 folinic acid Nutrition 0.000 title 1
239000011672 folinic acid Substances 0.000 title 1
229960001691 leucovorin Drugs 0.000 title 1
WFWLQNSHRPWKFK-ZCFIWIBFSA-N tegafur Chemical compound O=C1NC(=O)C(F)=CN1[C@@H]1OCCC1 WFWLQNSHRPWKFK-ZCFIWIBFSA-N 0.000 title 1
229960001674 tegafur Drugs 0.000 title 1
229940035893 uracil Drugs 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
- A61K31/7072—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid having two oxo groups directly attached to the pyrimidine ring, e.g. uridine, uridylic acid, thymidine, zidovudine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

PL02373247A 2001-04-26 2002-04-22 Sposób leczenia nowotworów drogą podawania tegafuru, uracylu, kwasu folinowego i cyklofosfoamidu PL373247A1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US28672901P	2001-04-26	2001-04-26

Publications (1)

Publication Number	Publication Date
PL373247A1 true PL373247A1 (pl)	2005-08-22

Family

ID=23099905

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL02373247A PL373247A1 (pl)	2001-04-26	2002-04-22	Sposób leczenia nowotworów drogą podawania tegafuru, uracylu, kwasu folinowego i cyklofosfoamidu

Country Status (10)

Country	Link
US (1)	US6620816B2 (pl)
EP (1)	EP1399021A1 (pl)
JP (1)	JP2004533434A (pl)
CA (1)	CA2445262A1 (pl)
CZ (1)	CZ20032835A3 (pl)
HU (1)	HUP0303953A3 (pl)
MX (1)	MXPA03009681A (pl)
NO (1)	NO20034690D0 (pl)
PL (1)	PL373247A1 (pl)
WO (1)	WO2002087335A1 (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4596220B2 (ja)	2001-06-26	2010-12-08	ソニー株式会社	画像処理装置および方法、記録媒体、並びにプログラム
EP1798689B1 (en) *	2001-06-26	2008-12-03	Sony Corporation	Image processing apparatus and method, and image-capturing apparatus
US7951780B2 (en) *	2004-02-25	2011-05-31	Astellas Pharma Inc.	Antitumor agent
JP2006160664A (ja) *	2004-12-07	2006-06-22	Vitamin C60 Bioresearch Kk	フリーラジカル疾患予防治療用組成物
ES2373867T3 (es) *	2007-03-02	2012-02-09	The University Of Wollongong	Composiciones y procedimientos para el suministro de agentes anticancerosos.
US20160067182A1 (en) *	2013-04-09	2016-03-10	Merrimack Pharmaceuticals, Inc.	Methods and compositions for improving outcomes of liposomal chemotherapy

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4328229A (en)	1978-03-29	1982-05-04	Taiho Pharmaceutical Company Limited	Anti-cancer composition for delivering 5-fluorouracil to cancer tissues
US5534513A (en) *	1991-09-05	1996-07-09	Taiho Pharmaceutical Company, Ltd.	Antitumor potentiator and antitumor composition
US5688773A (en) *	1994-08-17	1997-11-18	The General Hospital Corporation	Method of selectively destroying neoplastic cells

2002
- 2002-04-19 US US10/126,745 patent/US6620816B2/en not_active Expired - Fee Related
- 2002-04-22 MX MXPA03009681A patent/MXPA03009681A/es unknown
- 2002-04-22 EP EP02766793A patent/EP1399021A1/en not_active Withdrawn
- 2002-04-22 WO PCT/US2002/012769 patent/WO2002087335A1/en not_active Ceased
- 2002-04-22 PL PL02373247A patent/PL373247A1/pl not_active Application Discontinuation
- 2002-04-22 HU HU0303953A patent/HUP0303953A3/hu unknown
- 2002-04-22 CZ CZ20032835A patent/CZ20032835A3/cs unknown
- 2002-04-22 JP JP2002584700A patent/JP2004533434A/ja not_active Withdrawn
- 2002-04-22 CA CA002445262A patent/CA2445262A1/en not_active Abandoned
2003
- 2003-10-20 NO NO20034690A patent/NO20034690D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
US20020187956A1 (en)	2002-12-12
US6620816B2 (en)	2003-09-16
CZ20032835A3 (cs)	2007-06-20
HUP0303953A3 (en)	2005-05-30
JP2004533434A (ja)	2004-11-04
EP1399021A1 (en)	2004-03-24
NO20034690L (no)	2003-10-20
CA2445262A1 (en)	2002-11-07
MXPA03009681A (es)	2004-02-12
HUP0303953A2 (hu)	2004-04-28
WO2002087335A1 (en)	2002-11-07
NO20034690D0 (no)	2003-10-20

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Legal Events

Date	Code	Title	Description
2010-01-29	REFS	Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)