PL373872A1 - Pochodne indoloamidu, które posiadają aktywność hamowania fosforylazy glikogenowej - Google Patents
Pochodne indoloamidu, które posiadają aktywność hamowania fosforylazy glikogenowejInfo
- Publication number
- PL373872A1 PL373872A1 PL03373872A PL37387203A PL373872A1 PL 373872 A1 PL373872 A1 PL 373872A1 PL 03373872 A PL03373872 A PL 03373872A PL 37387203 A PL37387203 A PL 37387203A PL 373872 A1 PL373872 A1 PL 373872A1
- Authority
- PL
- Poland
- Prior art keywords
- indolamid
- derivatives
- inhibitory activity
- glycogen phosphorylase
- phosphorylase inhibitory
- Prior art date
Links
- VFHUJFBEFDVZPJ-UHFFFAOYSA-N 1h-indole-2-carboxamide Chemical class C1=CC=C2NC(C(=O)N)=CC2=C1 VFHUJFBEFDVZPJ-UHFFFAOYSA-N 0.000 title 1
- 102000007390 Glycogen Phosphorylase Human genes 0.000 title 1
- 108010046163 Glycogen Phosphorylase Proteins 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0205176.1A GB0205176D0 (en) | 2002-03-06 | 2002-03-06 | Chemical compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL373872A1 true PL373872A1 (pl) | 2005-09-19 |
Family
ID=9932340
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL03373872A PL373872A1 (pl) | 2002-03-06 | 2003-03-04 | Pochodne indoloamidu, które posiadają aktywność hamowania fosforylazy glikogenowej |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US7138415B2 (pl) |
| EP (1) | EP1483240A1 (pl) |
| JP (1) | JP2005524667A (pl) |
| KR (1) | KR20040097145A (pl) |
| CN (1) | CN100374420C (pl) |
| AR (1) | AR038889A1 (pl) |
| AU (1) | AU2003216988A1 (pl) |
| BR (1) | BR0308144A (pl) |
| CA (1) | CA2477717A1 (pl) |
| GB (1) | GB0205176D0 (pl) |
| IL (1) | IL163823A0 (pl) |
| IS (1) | IS7435A (pl) |
| MX (1) | MXPA04008612A (pl) |
| NO (1) | NO20044032L (pl) |
| NZ (1) | NZ534683A (pl) |
| PL (1) | PL373872A1 (pl) |
| RU (1) | RU2004125182A (pl) |
| TW (1) | TW200304817A (pl) |
| WO (1) | WO2003074484A1 (pl) |
| ZA (1) | ZA200406681B (pl) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0222912D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| GB0222909D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
| CA2503727A1 (en) * | 2002-11-07 | 2004-05-21 | Pfizer Products Inc. | Anti-diabetic agents |
| GB0318464D0 (en) * | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0319690D0 (en) * | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| WO2005020985A1 (en) * | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Indolamide derivatives which possess glycogen phosphorylase inhibitory activity |
| WO2006053274A2 (en) * | 2004-11-15 | 2006-05-18 | Bristol-Myers Squibb Company | 2-amino-1-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| US7223786B2 (en) | 2004-11-15 | 2007-05-29 | Bristol-Myers Squibb Company | 2-aminonaphthalene derivatives and related glycogen phosphorylase inhibitors |
| US7226942B2 (en) | 2004-11-15 | 2007-06-05 | Bristol-Myers Squibb Company | 2-amino-4-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| WO2006055463A2 (en) * | 2004-11-15 | 2006-05-26 | Bristol-Myers Squibb Company | 2-amino-3-functionalized tetralin derivatives and related glycogen phosphorylase inhibitors |
| EP1848693A1 (en) * | 2005-02-05 | 2007-10-31 | AstraZeneca AB | Indan-amide derivatives with glycogen phosphorylase inhibitory activity |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| BR112017004612A2 (pt) * | 2014-09-10 | 2018-01-30 | Epizyme, Inc. | compostos, composição farmacêutica, usos de um composto, e kit |
| CN112442022B (zh) * | 2019-09-02 | 2022-05-20 | 承德医学院 | 苯并嗪-4-酮类化合物、其制备方法及医药用途 |
| CN114403150B (zh) * | 2022-02-09 | 2022-11-04 | 中国农业大学 | 一种吲哚酰胺类化合物作为海藻糖-6-磷酸合成酶抑制剂的应用 |
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| DE200740C (pl) | ||||
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| GB0205165D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205170D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205166D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205175D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
| GB0205162D0 (en) | 2002-03-06 | 2002-04-17 | Astrazeneca Ab | Chemical compounds |
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| GB0222909D0 (en) | 2002-10-03 | 2002-11-13 | Astrazeneca Ab | Novel process and intermediates |
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| GB0318463D0 (en) | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0318464D0 (en) | 2003-08-07 | 2003-09-10 | Astrazeneca Ab | Chemical compounds |
| GB0319759D0 (en) | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| GB0319690D0 (en) | 2003-08-22 | 2003-09-24 | Astrazeneca Ab | Chemical compounds |
| WO2005020985A1 (en) | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Indolamide derivatives which possess glycogen phosphorylase inhibitory activity |
| WO2005020986A1 (en) | 2003-08-29 | 2005-03-10 | Astrazeneca Ab | Heterocyclic amide derivatives which posses glycogen phosphorylase inhibitory activity |
| GB0320422D0 (en) | 2003-08-30 | 2003-10-01 | Astrazeneca Ab | Chemical compounds |
-
2002
- 2002-03-06 GB GBGB0205176.1A patent/GB0205176D0/en not_active Ceased
-
2003
- 2003-03-04 CN CNB038053098A patent/CN100374420C/zh not_active Expired - Fee Related
- 2003-03-04 JP JP2003572954A patent/JP2005524667A/ja not_active Withdrawn
- 2003-03-04 RU RU2004125182/04A patent/RU2004125182A/ru not_active Application Discontinuation
- 2003-03-04 CA CA002477717A patent/CA2477717A1/en not_active Abandoned
- 2003-03-04 PL PL03373872A patent/PL373872A1/pl not_active Application Discontinuation
- 2003-03-04 EP EP03712310A patent/EP1483240A1/en not_active Withdrawn
- 2003-03-04 AU AU2003216988A patent/AU2003216988A1/en not_active Abandoned
- 2003-03-04 MX MXPA04008612A patent/MXPA04008612A/es active IP Right Grant
- 2003-03-04 US US10/506,554 patent/US7138415B2/en not_active Expired - Fee Related
- 2003-03-04 IL IL16382303A patent/IL163823A0/xx unknown
- 2003-03-04 KR KR10-2004-7013859A patent/KR20040097145A/ko not_active Ceased
- 2003-03-04 BR BR0308144-3A patent/BR0308144A/pt not_active IP Right Cessation
- 2003-03-04 WO PCT/GB2003/000883 patent/WO2003074484A1/en not_active Ceased
- 2003-03-04 NZ NZ534683A patent/NZ534683A/en unknown
- 2003-03-05 TW TW092104668A patent/TW200304817A/zh unknown
- 2003-03-06 AR ARP030100769A patent/AR038889A1/es unknown
-
2004
- 2004-08-23 ZA ZA200406681A patent/ZA200406681B/en unknown
- 2004-09-02 IS IS7435A patent/IS7435A/is unknown
- 2004-09-24 NO NO20044032A patent/NO20044032L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| IS7435A (is) | 2004-09-02 |
| EP1483240A1 (en) | 2004-12-08 |
| NO20044032L (no) | 2004-10-05 |
| JP2005524667A (ja) | 2005-08-18 |
| CN1639120A (zh) | 2005-07-13 |
| KR20040097145A (ko) | 2004-11-17 |
| GB0205176D0 (en) | 2002-04-17 |
| IL163823A0 (en) | 2005-12-18 |
| RU2004125182A (ru) | 2005-06-10 |
| NZ534683A (en) | 2006-02-24 |
| AR038889A1 (es) | 2005-02-02 |
| BR0308144A (pt) | 2004-12-07 |
| ZA200406681B (en) | 2005-09-22 |
| MXPA04008612A (es) | 2004-12-06 |
| CN100374420C (zh) | 2008-03-12 |
| AU2003216988A1 (en) | 2003-09-16 |
| US7138415B2 (en) | 2006-11-21 |
| US20050107362A1 (en) | 2005-05-19 |
| WO2003074484A1 (en) | 2003-09-12 |
| CA2477717A1 (en) | 2003-09-12 |
| TW200304817A (en) | 2003-10-16 |
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|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |