PL3740191T3 - Kompozycje oftalmiczne zawierające bilastynę, beta-cyklodektrynę i co najmniej jeden środek żelatujący - Google Patents

Kompozycje oftalmiczne zawierające bilastynę, beta-cyklodektrynę i co najmniej jeden środek żelatujący

Info

Publication number
PL3740191T3
PL3740191T3 PL19701154T PL19701154T PL3740191T3 PL 3740191 T3 PL3740191 T3 PL 3740191T3 PL 19701154 T PL19701154 T PL 19701154T PL 19701154 T PL19701154 T PL 19701154T PL 3740191 T3 PL3740191 T3 PL 3740191T3
Authority
PL
Poland
Prior art keywords
bilastine
cyclodextrin
beta
gelling agent
ophthalmic compositions
Prior art date
Application number
PL19701154T
Other languages
English (en)
Inventor
Gonzalo HERNÁNDEZ HERRERO
Ana GONZALO GOROSTIZA
Pablo MORÁN POLADURA
Arturo ZAZPE ARCE
Nieves FERNÁNDEZ HERNANDO
Tania GONZÁLEZ GARCÍA
Paloma Tato Cerdeiras
Francisco Javier Otero Espinar
Anxo FERNÁNDEZ FERREIRO
Victoria DÍAZ TOMÉ
Original Assignee
Faes Farma, S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Faes Farma, S.A. filed Critical Faes Farma, S.A.
Publication of PL3740191T3 publication Critical patent/PL3740191T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
PL19701154T 2018-01-18 2019-01-09 Kompozycje oftalmiczne zawierające bilastynę, beta-cyklodektrynę i co najmniej jeden środek żelatujący PL3740191T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP18382021 2018-01-18
EP19701154.7A EP3740191B1 (en) 2018-01-18 2019-01-09 Ophthalmic compositions comprising bilastine, a beta-cyclodextrin and at least one gelling agent
PCT/EP2019/050433 WO2019141563A1 (en) 2018-01-18 2019-01-09 Ophthalmic compositions comprising bilastine, a beta-cyclodextrin and at least one gelling agent

Publications (1)

Publication Number Publication Date
PL3740191T3 true PL3740191T3 (pl) 2021-11-29

Family

ID=61017875

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19701154T PL3740191T3 (pl) 2018-01-18 2019-01-09 Kompozycje oftalmiczne zawierające bilastynę, beta-cyklodektrynę i co najmniej jeden środek żelatujący

Country Status (28)

Country Link
US (2) US20210128544A1 (pl)
EP (2) EP3915539A1 (pl)
JP (1) JP7309729B2 (pl)
KR (1) KR102695627B1 (pl)
CN (1) CN111727035B (pl)
AR (1) AR114216A1 (pl)
AU (1) AU2019209214B2 (pl)
CA (1) CA3088740A1 (pl)
CL (1) CL2020001895A1 (pl)
CO (1) CO2020009992A2 (pl)
CY (1) CY1124270T1 (pl)
DK (1) DK3740191T3 (pl)
EA (1) EA202091725A1 (pl)
ES (1) ES2878107T3 (pl)
HR (1) HRP20211037T1 (pl)
HU (1) HUE054594T2 (pl)
LT (1) LT3740191T (pl)
MA (1) MA51612B1 (pl)
MX (1) MX2020007692A (pl)
PL (1) PL3740191T3 (pl)
PT (1) PT3740191T (pl)
PY (1) PY1903392A (pl)
SA (1) SA520412443B1 (pl)
SI (1) SI3740191T1 (pl)
TW (1) TWI833727B (pl)
UY (1) UY38055A (pl)
WO (1) WO2019141563A1 (pl)
ZA (1) ZA202005077B (pl)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025508704A (ja) 2022-02-17 2025-04-10 ファエス・ファルマ・ソシエダッド・アノニマ １日１回非経口投与のためのビラスチン組成物
CN116211795B (zh) * 2022-12-26 2025-09-26 深圳市贝美药业有限公司 一种比拉斯汀口服液体制剂及其制备方法
CN115970066B (zh) * 2022-12-29 2024-09-27 成都爱睿康乐医疗器械有限公司 基于主客体相互作用的载药纳米凝胶生物润滑剂及其制备方法和应用
WO2024224326A1 (en) * 2023-04-27 2024-10-31 Leiutis Pharmaceuticals Llp Liquid parenteral formulations of bilastine
WO2024224308A1 (en) * 2023-04-27 2024-10-31 Leiutis Pharmaceuticals Llp Liquid parenteral formulations of bilastine free of cyclodextrins
WO2024256956A1 (en) * 2023-06-13 2024-12-19 Leiutis Pharmaceuticals Llp Stable formulations of bilastine for nasal and ophthalmic use

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1229075B (it) * 1985-04-05 1991-07-17 Fidia Farmaceutici Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico
ES2048109B1 (es) 1992-07-20 1994-12-16 Espanola Prod Quimicos Procedimiento de preparacion de nuevos derivados piperidicos del bencimidazol.
JP3527256B2 (ja) 1992-12-09 2004-05-17 ロート製薬株式会社 抗アレルギー点眼剤
TW401300B (en) * 1992-12-25 2000-08-11 Senju Pharma Co Antiallergic composition for ophthalmic or nasal use
ES2124167B1 (es) 1996-06-04 1999-09-16 Espanola Prod Quimicos Nuevos derivados del bencimidazol con actividad antihistaminica.
DE10161149B4 (de) 2001-12-12 2007-03-08 Ursapharm Arzneimittel Gmbh & Co. Kg Verwendung von Heparin-haltigem Ophthalmikum
SI1505066T1 (sl) 2002-04-19 2007-04-30 Faes Farma Sa Polimorf 4-(2-(4-(1-(2-etoksietil)-1h-benzimidazol-2-il) -1-piperidinil)-alfa, alfa-dimetil-benzenocetne kisline
US20050239745A1 (en) 2004-03-03 2005-10-27 Ophthalmic Research Associates, Inc. Novel topical ophthalmic formulations
US7247623B2 (en) * 2005-08-19 2007-07-24 Inspire Pharmaceuticals, Inc. Method of treating dry eye disease with non-drying antihistamines
US20070082870A1 (en) 2005-10-11 2007-04-12 Buchanan Charles M Pharmaceutical formulations of cyclodextrins and antifungal azole compounds
JP5292277B2 (ja) 2006-03-31 2013-09-18 ビスタコン・フアーマシユーチカルズ・エルエルシー 眼アレルギーの処置
CN101460176B (zh) * 2006-03-31 2012-11-28 维斯塔肯药品有限责任公司 眼变态反应治疗
CN101795565A (zh) 2007-06-28 2010-08-04 锡德克斯药物公司 皮质类固醇水溶液的鼻部和眼部给药
WO2010107525A1 (en) 2009-03-17 2010-09-23 Aciex Therapeutics, Inc. Ophthalmic formulations of ketotifen and methods of use
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
CN103110575B (zh) * 2013-03-07 2014-11-05 宁夏康亚药业有限公司 一种美洛昔康滴眼液及其制备方法和应用
WO2014150899A1 (en) 2013-03-15 2014-09-25 Chapin Matthew J Topical ophthalmic formulations for treating migraine
CN103784462A (zh) * 2014-02-25 2014-05-14 宋俊智 包含比拉斯汀及甾族化合物的药物制剂
EP3040334A1 (en) 2014-12-29 2016-07-06 Faes Farma, S.A. New benzimidazole derivatives as antihistamine agents

Also Published As

Publication number Publication date
ZA202005077B (en) 2024-12-18
ES2878107T3 (es) 2021-11-18
AU2019209214A1 (en) 2020-08-13
HUE054594T2 (hu) 2021-09-28
KR102695627B1 (ko) 2024-08-16
AU2019209214B2 (en) 2023-11-23
MA51612B1 (fr) 2021-06-30
MX2020007692A (es) 2020-09-14
WO2019141563A1 (en) 2019-07-25
KR20200111727A (ko) 2020-09-29
UY38055A (es) 2019-08-30
AR114216A1 (es) 2020-08-05
JP7309729B2 (ja) 2023-07-18
US20210128544A1 (en) 2021-05-06
HRP20211037T1 (hr) 2021-10-01
TWI833727B (zh) 2024-03-01
LT3740191T (lt) 2021-08-10
CO2020009992A2 (es) 2021-01-18
SA520412443B1 (ar) 2022-09-01
JP2021511317A (ja) 2021-05-06
EP3915539A1 (en) 2021-12-01
TW201932110A (zh) 2019-08-16
EP3740191B1 (en) 2021-04-28
CL2020001895A1 (es) 2020-12-04
CN111727035A (zh) 2020-09-29
US20260027099A1 (en) 2026-01-29
CA3088740A1 (en) 2019-07-25
PT3740191T (pt) 2021-07-09
PY1903392A (es) 2019-08-01
BR112020014265A2 (pt) 2020-12-08
EP3740191A1 (en) 2020-11-25
DK3740191T3 (da) 2021-06-07
MA51612A (fr) 2020-11-25
SI3740191T1 (sl) 2021-09-30
CY1124270T1 (el) 2022-07-22
EA202091725A1 (ru) 2020-10-12
CN111727035B (zh) 2024-05-28

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