PL3741744T3 - Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny - Google Patents

Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny

Info

Publication number
PL3741744T3
PL3741744T3 PL19460027T PL19460027T PL3741744T3 PL 3741744 T3 PL3741744 T3 PL 3741744T3 PL 19460027 T PL19460027 T PL 19460027T PL 19460027 T PL19460027 T PL 19460027T PL 3741744 T3 PL3741744 T3 PL 3741744T3
Authority
PL
Poland
Prior art keywords
pharmaceutical intermediate
preparing pimavanserin
pimavanserin
preparing
pharmaceutical
Prior art date
Application number
PL19460027T
Other languages
English (en)
Inventor
Adam Haluszczuk
Dorota Pogoda
Original Assignee
Zakłady Farmaceutyczne "Polpharma" S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zakłady Farmaceutyczne "Polpharma" S.A. filed Critical Zakłady Farmaceutyczne "Polpharma" S.A.
Publication of PL3741744T3 publication Critical patent/PL3741744T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C07D211/58—Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
PL19460027T 2019-05-22 2019-05-22 Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny PL3741744T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19460027.6A EP3741744B1 (en) 2019-05-22 2019-05-22 A pharmaceutical intermediate for preparing pimavanserin

Publications (1)

Publication Number Publication Date
PL3741744T3 true PL3741744T3 (pl) 2022-04-25

Family

ID=66951873

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19460027T PL3741744T3 (pl) 2019-05-22 2019-05-22 Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny

Country Status (5)

Country Link
US (2) US12215081B2 (pl)
EP (1) EP3741744B1 (pl)
ES (1) ES2906868T3 (pl)
PL (1) PL3741744T3 (pl)
WO (1) WO2020234383A1 (pl)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2908812T3 (es) * 2019-04-17 2022-05-04 Zakl Farmaceutyczne Polpharma S A Proceso para la preparación de un agente farmacéutico
TWI924824B (zh) * 2021-03-26 2026-05-11 大陸商上海雲晟研新生物科技股份有限公司 哌馬色林藥用鹽、製備方法、含其的藥物組合物及應用
CN120870375A (zh) * 2025-07-01 2025-10-31 广东隆赋药业股份有限公司 匹莫范色林起始物料n-甲基-4-哌啶酮有关物质的气相色谱分离检测方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101031548B (zh) * 2004-09-27 2011-04-06 阿卡蒂亚药品公司 N-(4-氟苄基)-n-(1-甲基哌啶-4-基)-n'-(4-(2-甲基丙氧基)-苯基甲基)脲的盐及其制备
US7790899B2 (en) 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
WO2009039461A2 (en) * 2007-09-21 2009-03-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
EP3271018B1 (en) 2015-03-02 2020-12-23 Pliva Hrvatska D.O.O. Processes and intermediates for the preparation of pimavanserin
WO2019040107A1 (en) * 2017-08-21 2019-02-28 Acadia Pharmaceuticals Inc. COMPOUNDS, CORRESPONDING SALTS AND METHODS FOR THE TREATMENT OF DISEASES
CN108358817A (zh) * 2018-03-05 2018-08-03 丽珠集团新北江制药股份有限公司 一种匹莫范色林中间体及匹莫范色林的制备方法

Also Published As

Publication number Publication date
EP3741744A1 (en) 2020-11-25
EP3741744B1 (en) 2022-01-05
ES2906868T3 (es) 2022-04-20
WO2020234383A1 (en) 2020-11-26
US20220213037A1 (en) 2022-07-07
US20250129026A1 (en) 2025-04-24
US12215081B2 (en) 2025-02-04

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