PL3741744T3 - Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny - Google Patents

Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny

Info

Publication number
PL3741744T3
PL3741744T3 PL19460027T PL19460027T PL3741744T3 PL 3741744 T3 PL3741744 T3 PL 3741744T3 PL 19460027 T PL19460027 T PL 19460027T PL 19460027 T PL19460027 T PL 19460027T PL 3741744 T3 PL3741744 T3 PL 3741744T3
Authority
PL
Poland
Prior art keywords
pharmaceutical intermediate
preparing pimavanserin
pimavanserin
preparing
pharmaceutical
Prior art date
Application number
PL19460027T
Other languages
English (en)
Inventor
Adam Haluszczuk
Dorota Pogoda
Original Assignee
Zakłady Farmaceutyczne "Polpharma" S.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zakłady Farmaceutyczne "Polpharma" S.A. filed Critical Zakłady Farmaceutyczne "Polpharma" S.A.
Publication of PL3741744T3 publication Critical patent/PL3741744T3/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56Nitrogen atoms
    • C07D211/58Nitrogen atoms attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
PL19460027T 2019-05-22 2019-05-22 Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny PL3741744T3 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP19460027.6A EP3741744B1 (en) 2019-05-22 2019-05-22 A pharmaceutical intermediate for preparing pimavanserin

Publications (1)

Publication Number Publication Date
PL3741744T3 true PL3741744T3 (pl) 2022-04-25

Family

ID=66951873

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19460027T PL3741744T3 (pl) 2019-05-22 2019-05-22 Farmaceutyczny produkt pośredni do wytwarzania pimawanseryny

Country Status (5)

Country Link
US (2) US12215081B2 (pl)
EP (1) EP3741744B1 (pl)
ES (1) ES2906868T3 (pl)
PL (1) PL3741744T3 (pl)
WO (1) WO2020234383A1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3725774B1 (en) * 2019-04-17 2022-02-23 Zaklady Farmaceutyczne Polpharma S.A. Process for the preparation of a pharmaceutical agent
WO2022199707A1 (zh) * 2021-03-26 2022-09-29 上海博志研新药物技术有限公司 哌马色林药用盐、制备方法、含其的药物组合物及应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7790899B2 (en) 2004-09-27 2010-09-07 Acadia Pharmaceuticals, Inc. Synthesis of N-(4-fluorobenzyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl)carbamide and its tartrate salt and crystalline forms
JP4996467B2 (ja) * 2004-09-27 2012-08-08 アカディア ファーマシューティカルズ インコーポレイテッド N−(4−フルオロベンジル)−n−(1−メチルピペリジン−4−イル)−n’−(4−(2−メチルプロピルオキシ)フェニルメチル)カルバミド、並びにその酒石酸塩及び結晶形態の合成
WO2009039461A2 (en) * 2007-09-21 2009-03-26 Acadia Pharmaceuticals, Inc. N-substituted piperidine derivatives as serotonin receptor agents
WO2016141003A1 (en) 2015-03-02 2016-09-09 Teva Pharmaceutical Industries Ltd. Processes and intermediates for the preparation of pimavanserin
SG11202001062XA (en) * 2017-08-21 2020-03-30 Acadia Pharm Inc Compounds, salts thereof and methods for treatment of diseases
CN108358817A (zh) * 2018-03-05 2018-08-03 丽珠集团新北江制药股份有限公司 一种匹莫范色林中间体及匹莫范色林的制备方法

Also Published As

Publication number Publication date
US20220213037A1 (en) 2022-07-07
EP3741744A1 (en) 2020-11-25
US20250129026A1 (en) 2025-04-24
WO2020234383A1 (en) 2020-11-26
US12215081B2 (en) 2025-02-04
EP3741744B1 (en) 2022-01-05
ES2906868T3 (es) 2022-04-20

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