PL374349A1 - Hcv fusion proteins with modified ns3 domains - Google Patents

Hcv fusion proteins with modified ns3 domains

Info

Publication number
PL374349A1
PL374349A1 PL03374349A PL37434903A PL374349A1 PL 374349 A1 PL374349 A1 PL 374349A1 PL 03374349 A PL03374349 A PL 03374349A PL 37434903 A PL37434903 A PL 37434903A PL 374349 A1 PL374349 A1 PL 374349A1
Authority
PL
Poland
Prior art keywords
domains
modified
fusion proteins
hcv fusion
hcv
Prior art date
Application number
PL03374349A
Other languages
English (en)
Polish (pl)
Inventor
Michael Houghton
Original Assignee
Chiron Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corporation filed Critical Chiron Corporation
Publication of PL374349A1 publication Critical patent/PL374349A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/503—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses
    • C12N9/506—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from viruses derived from RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/24011—Flaviviridae
    • C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
    • C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL03374349A 2002-07-02 2003-07-02 Hcv fusion proteins with modified ns3 domains PL374349A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39369402P 2002-07-02 2002-07-02
US39451002P 2002-07-08 2002-07-08

Publications (1)

Publication Number Publication Date
PL374349A1 true PL374349A1 (en) 2005-10-17

Family

ID=30118384

Family Applications (1)

Application Number Title Priority Date Filing Date
PL03374349A PL374349A1 (en) 2002-07-02 2003-07-02 Hcv fusion proteins with modified ns3 domains

Country Status (8)

Country Link
EP (1) EP1539809A4 (fr)
JP (2) JP2005532064A (fr)
CN (1) CN1678630A (fr)
AU (1) AU2003248818A1 (fr)
CA (1) CA2491508A1 (fr)
PL (1) PL374349A1 (fr)
RU (1) RU2005102484A (fr)
WO (1) WO2004005473A2 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7491808B2 (en) * 2000-06-15 2009-02-17 Novartis Vaccines And Diagnostics, Inc. HCV non-structural protein mutants and uses thereof
EP1576125A4 (fr) * 2002-10-25 2008-09-03 Novartis Vaccines & Diagnostic Activation de lymphocytes specifiques du vhc
US7439042B2 (en) 2002-12-16 2008-10-21 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
CA2566725A1 (fr) * 2004-05-17 2005-12-01 Chiron Corporation Domaine ns5 du virus de l'hepatite c tronque et proteines hybrides comprenant ce dernier
EP1802778B1 (fr) 2004-08-27 2011-10-05 Novartis Vaccines and Diagnostics, Inc. Antigenes de fusion a epitopes multiples hcv presentant des sites de clivage proteolytiques modifies et utilisations associees
AU2011254055B2 (en) * 2004-10-18 2012-12-20 Globeimmune, Inc. Yeast-based therapeutic for chronic hepatitis C infection
EP2460533A3 (fr) * 2004-10-18 2014-01-08 Globeimmune, Inc. Moyens thérapeutiques à base de levure contre l'infection par hépatite C chronique
CA2618429A1 (fr) * 2005-05-25 2007-03-22 Tripep Ab Gene de fusion ns3/4a non structurel de l'hepatite c
CA2623329A1 (fr) * 2005-10-13 2007-04-19 Virexx Medical Corp. Antigene chimere contenant un polypeptide du virus de l'hepatite c et un fragment fc destine a provoquer une reponse immunitaire
GB0524408D0 (en) * 2005-11-30 2006-01-11 Glaxosmithkline Biolog Sa Vaccines
ES2536426T3 (es) 2006-03-23 2015-05-25 Novartis Ag Compuestos de imidazoquinoxalina como inmunomoduladores
US8216590B2 (en) * 2006-08-25 2012-07-10 Novartis Ag HCV fusion polypeptides
WO2010033841A1 (fr) 2008-09-19 2010-03-25 Globeimmune, Inc. Immunothérapie pour infection chronique par le virus de l'hépatite c
WO2012038950A1 (fr) 2010-09-20 2012-03-29 Ramot At Tel-Aviv University Ltd. Complexes de toxine activables comprenant un peptide inhibiteur clivable
CA2980718C (fr) * 2015-03-27 2021-06-01 Ortho-Clinical Diagnostics, Inc. Polypeptides ns4a/ns3 modifie du vhc et leurs utilisations
CN106749672B (zh) * 2016-11-18 2020-06-30 江西农业大学 一种丙型肝炎病毒融合抗原蛋白及其应用
CN111153963B (zh) * 2020-01-19 2021-08-10 华南理工大学 抗炎五肽及其提取分离方法和在改善记忆中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE236981T1 (de) * 1993-11-04 2003-04-15 Innogenetics Nv Von menschlichen t-zellen immunodominante epiropen des virus der c-hepatitis
WO2001038360A2 (fr) * 1999-11-24 2001-05-31 Chiron Corporation Polypeptide non structurel du virus de l'hepatite c
WO2001090812A1 (fr) * 2000-05-23 2001-11-29 Massachusetts Institute Of Technology Dispositifs non lineaires de fluorure ultraviolet

Also Published As

Publication number Publication date
RU2005102484A (ru) 2006-01-20
JP2005532064A (ja) 2005-10-27
CN1678630A (zh) 2005-10-05
EP1539809A2 (fr) 2005-06-15
WO2004005473A2 (fr) 2004-01-15
AU2003248818A1 (en) 2004-01-23
JP2006265267A (ja) 2006-10-05
WO2004005473A3 (fr) 2004-04-01
EP1539809A4 (fr) 2006-03-08
CA2491508A1 (fr) 2004-01-15

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Legal Events

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