PL375632A1 - Synergistyczna kombinacja zawierająca roflumilasti (R, R)-formoterol - Google Patents

Synergistyczna kombinacja zawierająca roflumilasti (R, R)-formoterol

Info

Publication number: PL375632A1
Authority: PL; Poland
Prior art keywords: roflumilast; formoterol; synergistic combination; treatment; relates
Prior art date: 2002-11-27

Application number

PL03375632A

Other languages

English (en)

Other versions

PL214869B1 (pl

Inventor

Rolf Beume

Daniela Bundschuh

Degenhard Marx

Christian Weimar

Stefan-Lutz Wollin

Original Assignee

Altana Pharma Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-11-27

Filing date

2003-11-26

Publication date

2005-12-12

2003-11-26 Application filed by Altana Pharma Ag filed Critical Altana Pharma Ag

2005-12-12 Publication of PL375632A1 publication Critical patent/PL375632A1/pl

2013-09-30 Publication of PL214869B1 publication Critical patent/PL214869B1/pl

Links

BPZSYCZIITTYBL-YJYMSZOUSA-N R-Formoterol Chemical compound C1=CC(OC)=CC=C1C[C@@H](C)NC[C@H](O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-YJYMSZOUSA-N 0.000 title abstract 2
MNDBXUUTURYVHR-UHFFFAOYSA-N roflumilast Chemical compound FC(F)OC1=CC=C(C(=O)NC=2C(=CN=CC=2Cl)Cl)C=C1OCC1CC1 MNDBXUUTURYVHR-UHFFFAOYSA-N 0.000 title abstract 2
229960002586 roflumilast Drugs 0.000 title abstract 2
239000011885 synergistic combination Substances 0.000 title 1
208000018569 Respiratory Tract disease Diseases 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators

Landscapes

Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Pain & Pain Management (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL375632A 2002-11-27 2003-11-26 Synergistyczna kombinacja zawierajaca roflumilast i (R, R)-formoterol PL214869B1 (pl)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP02026504		2002-11-27

Publications (2)

Publication Number	Publication Date
PL375632A1 true PL375632A1 (pl)	2005-12-12
PL214869B1 PL214869B1 (pl)	2013-09-30

Family

ID=32338001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL375632A PL214869B1 (pl)	2002-11-27	2003-11-26	Synergistyczna kombinacja zawierajaca roflumilast i (R, R)-formoterol

Country Status (31)

Country	Link
US (1)	US20060199865A1 (pl)
EP (1)	EP1567140B1 (pl)
JP (1)	JP2006508993A (pl)
KR (1)	KR20050094810A (pl)
CN (1)	CN1713902A (pl)
AT (1)	ATE399544T1 (pl)
AU (1)	AU2003288169B8 (pl)
BR (1)	BR0316475A (pl)
CA (1)	CA2506956C (pl)
CO (1)	CO5690571A2 (pl)
CY (1)	CY1110368T1 (pl)
DE (1)	DE60321954D1 (pl)
DK (1)	DK1567140T3 (pl)
EA (1)	EA009990B1 (pl)
ES (1)	ES2309374T3 (pl)
HR (1)	HRP20050580B1 (pl)
IL (1)	IL168307A (pl)
IS (1)	IS2576B (pl)
MA (1)	MA27538A1 (pl)
ME (1)	ME00488B (pl)
MX (1)	MXPA05005438A (pl)
NO (1)	NO334148B1 (pl)
NZ (1)	NZ540658A (pl)
PL (1)	PL214869B1 (pl)
PT (1)	PT1567140E (pl)
RS (1)	RS51082B (pl)
SI (1)	SI1567140T1 (pl)
TN (1)	TNSN05130A1 (pl)
UA (1)	UA83017C2 (pl)
WO (1)	WO2004047828A1 (pl)
ZA (1)	ZA200503307B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MY140561A (en) *	2002-02-20	2009-12-31	Nycomed Gmbh	Dosage form containing pde 4 inhibitor as active ingredient
EA009985B1 (ru)	2003-03-10	2008-04-28	Никомед Гмбх	Новый способ получения рофлумиласта
ES2421916T3 (es)	2005-03-16	2013-09-06	Nycomed Gmbh	Forma farmacéutica de sabor enmascarado que contiene roflumilast
WO2013077830A1 (en) *	2011-11-25	2013-05-30	Mahmut Bilgic	Synergistilly active combinations of roflumilast and carmoterol
CN103784443A (zh) *	2014-02-18	2014-05-14	青岛市城阳区人民医院	一种包含沙美特罗和罗氟司特的药物组合产品

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5795564A (en) *	1991-04-05	1998-08-18	Sepracor, Inc.	Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
WO1998021175A1 (en) *	1996-11-11	1998-05-22	Sepracor, Inc.	Process for the preparation of optically pure isomers of formoterol
TR199901772T2 (pl) *	1997-02-17	1999-09-21	Byk Gulden Lomberg Chemische Fabrik Gmbh
PT975347E (pt) *	1997-02-28	2008-05-23	Nycomed Gmbh	Combinação sinérgica de inibidores da pde e agonistas da adenilato ciclase ou agonistas da guanil ciclise
US6624181B1 (en) *	1997-02-28	2003-09-23	Altana Pharma Ag	Synergistic combination
CA2341488A1 (en) *	1998-08-26	2000-03-09	Smithkline Beecham Corporation	Therapies for treating pulmonary diseases
US6303145B2 (en) *	1999-05-10	2001-10-16	Sepracor Inc.	(S,R) formoterol methods and compositions
PL200923B1 (pl) *	1999-08-21	2009-02-27	Nycomed Gmbh	Lek zawierający inhibitor PDE w połączeniu z agonistą receptoraß₂ -adrenergicznego oraz zastosowanie połączenia roflumilastu i salmeterolu
GB0103630D0 (en) *	2001-02-14	2001-03-28	Glaxo Group Ltd	Chemical compounds
ATE381537T1 (de) *	2001-03-22	2008-01-15	Glaxo Group Ltd	Formanilid-derivative als beta2-adrenorezeptor- agonisten
AR033290A1 (es) *	2001-04-30	2003-12-10	Glaxo Group Ltd	Derivados antiinflamatorios de androstano

2003
- 2003-11-26 DE DE60321954T patent/DE60321954D1/de not_active Expired - Lifetime
- 2003-11-26 CA CA2506956A patent/CA2506956C/en not_active Expired - Fee Related
- 2003-11-26 DK DK03780056T patent/DK1567140T3/da active
- 2003-11-26 HR HRP20050580AA patent/HRP20050580B1/hr not_active IP Right Cessation
- 2003-11-26 PL PL375632A patent/PL214869B1/pl unknown
- 2003-11-26 EP EP03780056A patent/EP1567140B1/en not_active Expired - Lifetime
- 2003-11-26 CN CNA2003801036335A patent/CN1713902A/zh active Pending
- 2003-11-26 ES ES03780056T patent/ES2309374T3/es not_active Expired - Lifetime
- 2003-11-26 RS YUP-2005/0383A patent/RS51082B/sr unknown
- 2003-11-26 NZ NZ540658A patent/NZ540658A/en not_active IP Right Cessation
- 2003-11-26 EA EA200500865A patent/EA009990B1/ru not_active IP Right Cessation
- 2003-11-26 PT PT03780056T patent/PT1567140E/pt unknown
- 2003-11-26 ME MEP-2008-781A patent/ME00488B/me unknown
- 2003-11-26 AU AU2003288169A patent/AU2003288169B8/en not_active Ceased
- 2003-11-26 WO PCT/EP2003/013266 patent/WO2004047828A1/en not_active Ceased
- 2003-11-26 UA UAA200505965A patent/UA83017C2/uk unknown
- 2003-11-26 AT AT03780056T patent/ATE399544T1/de active
- 2003-11-26 KR KR1020057009176A patent/KR20050094810A/ko not_active Ceased
- 2003-11-26 US US10/535,817 patent/US20060199865A1/en not_active Abandoned
- 2003-11-26 JP JP2004554476A patent/JP2006508993A/ja active Pending
- 2003-11-26 MX MXPA05005438A patent/MXPA05005438A/es active IP Right Grant
- 2003-11-26 SI SI200331345T patent/SI1567140T1/sl unknown
- 2003-11-26 BR BR0316475-6A patent/BR0316475A/pt not_active IP Right Cessation
2005
- 2005-04-25 ZA ZA200503307A patent/ZA200503307B/en unknown
- 2005-05-01 IL IL168307A patent/IL168307A/en not_active IP Right Cessation
- 2005-05-10 TN TNP2005000130A patent/TNSN05130A1/en unknown
- 2005-06-16 MA MA28342A patent/MA27538A1/fr unknown
- 2005-06-20 NO NO20053023A patent/NO334148B1/no not_active IP Right Cessation
- 2005-06-20 IS IS7899A patent/IS2576B/is unknown
- 2005-06-27 CO CO05062790A patent/CO5690571A2/es not_active Application Discontinuation
2008
- 2008-09-17 CY CY20081101016T patent/CY1110368T1/el unknown

Also Published As

Publication number	Publication date
CO5690571A2 (es)	2006-10-31
SI1567140T1 (sl)	2008-12-31
NO334148B1 (no)	2013-12-16
DK1567140T3 (da)	2008-11-03
US20060199865A1 (en)	2006-09-07
ZA200503307B (en)	2006-11-29
ES2309374T3 (es)	2008-12-16
RS51082B (sr)	2010-10-31
JP2006508993A (ja)	2006-03-16
ME00488B (me)	2011-10-10
EA009990B1 (ru)	2008-04-28
NO20053023L (no)	2005-06-20
AU2003288169B2 (en)	2010-01-07
ATE399544T1 (de)	2008-07-15
RS20050383A (sr)	2007-08-03
CA2506956A1 (en)	2004-06-10
PL214869B1 (pl)	2013-09-30
MXPA05005438A (es)	2005-08-03
HRP20050580B1 (hr)	2014-04-11
HRP20050580A2 (en)	2006-08-31
NZ540658A (en)	2007-03-30
EP1567140A1 (en)	2005-08-31
EP1567140B1 (en)	2008-07-02
MA27538A1 (fr)	2005-09-01
TNSN05130A1 (en)	2007-05-14
KR20050094810A (ko)	2005-09-28
BR0316475A (pt)	2005-10-11
UA83017C2 (uk)	2008-06-10
IS7899A (is)	2005-06-20
CN1713902A (zh)	2005-12-28
AU2003288169B8 (en)	2010-08-26
HK1081862A1 (en)	2006-05-26
CY1110368T1 (el)	2015-04-29
IS2576B (is)	2010-02-15
IL168307A (en)	2010-12-30
PT1567140E (pt)	2008-09-24
AU2003288169A1 (en)	2004-06-18
EA200500865A1 (ru)	2005-12-29
CA2506956C (en)	2012-10-02
DE60321954D1 (de)	2008-08-14
WO2004047828A1 (en)	2004-06-10

Publication	Publication Date	Title
MXPA03011515A (es)	2004-03-18	Nuevas composiciones de medicamentos sobre la base de agentes anticolinergicos, corticoesteroides y agentes betamimeticos.
EP1558220A4 (en)	2006-07-12	ORAL COMPOSITIONS FOR THE TREATMENT OF DISEASES
HU229439B1 (hu)	2013-12-30	Roflumilast és salmeterol szinergetikus kombinációja
MXPA05012358A (es)	2006-02-02	Combinacion farmaceutica que comprende modafinilo y otra droga.
CY1110369T1 (el)	2015-04-29	Νεος συνεργιστικος συνδυασμος ο οποιος περιεχει ροφλουμιλαστη και φορμοτερολη
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CY1110368T1 (el)	2015-04-29	Συνεργιστικος συνδυασμος ο οποιος περιλαμβανει ροφλουμιλαστη και (r,r)-φορμοτερολη
TWI347845B (en)	2011-09-01	Pharmaceutical compositions,combinations,and kits for the treatment of respiratory diseases and use of the same
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