PL375821A1 - Sposób syntezy peptydów zawierających podstruktury 4-hydroksy-proliny - Google Patents

Sposób syntezy peptydów zawierających podstruktury 4-hydroksy-proliny

Info

Publication number: PL375821A1
Authority: PL; Poland
Prior art keywords: hydroxy; peptide synthesis; peptides containing; substructure; proline
Prior art date: 2002-12-12

Application number

PL03375821A

Other languages

English (en)

Other versions

PL206914B1 (pl

Inventor

Bernhard Wietfeld

Walter Prikoszovich

Bernhard Erb

Werner Pachinger

Original Assignee

Novartis Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-12-12

Filing date

2003-12-11

Publication date

2005-12-12

2002-12-12 Priority claimed from GB0229020A external-priority patent/GB0229020D0/en

2002-12-16 Priority claimed from GB0229280A external-priority patent/GB0229280D0/en

2003-12-11 Application filed by Novartis Ag filed Critical Novartis Ag

2005-12-12 Publication of PL375821A1 publication Critical patent/PL375821A1/pl

2010-10-29 Publication of PL206914B1 publication Critical patent/PL206914B1/pl

Links

238000000034 method Methods 0.000 title abstract 3
102000004196 processed proteins & peptides Human genes 0.000 title abstract 2
108090000765 processed proteins & peptides Proteins 0.000 title abstract 2
PMMYEEVYMWASQN-DMTCNVIQSA-N Hydroxyproline Chemical compound O[C@H]1CN[C@H](C(O)=O)C1 PMMYEEVYMWASQN-DMTCNVIQSA-N 0.000 title 1
PMMYEEVYMWASQN-UHFFFAOYSA-N dl-hydroxyproline Natural products OC1C[NH2+]C(C([O-])=O)C1 PMMYEEVYMWASQN-UHFFFAOYSA-N 0.000 title 1
229960002591 hydroxyproline Drugs 0.000 title 1
238000010647 peptide synthesis reaction Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C65/00—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C65/01—Compounds having carboxyl groups bound to carbon atoms of six—membered aromatic rings and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups containing hydroxy or O-metal groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Pyrrole Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

PL375821A 2002-12-12 2003-12-11 Sposób otrzymywania pochodnych 4-hydroksy-proliny do syntezy peptydów oraz pochodne 4-hydroksy-proliny PL206914B1 (pl)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB0229020A GB0229020D0 (en)	2002-12-12	2002-12-12	Organic compounds
GB0229280A GB0229280D0 (en)	2002-12-16	2002-12-16	Organic compounds

Publications (2)

Publication Number	Publication Date
PL375821A1 true PL375821A1 (pl)	2005-12-12
PL206914B1 PL206914B1 (pl)	2010-10-29

Family

ID=32510405

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL375821A PL206914B1 (pl)	2002-12-12	2003-12-11	Sposób otrzymywania pochodnych 4-hydroksy-proliny do syntezy peptydów oraz pochodne 4-hydroksy-proliny

Country Status (23)

Country	Link
US (3)	US7294722B2 (pl)
EP (1)	EP1572615B8 (pl)
JP (2)	JP4796303B2 (pl)
KR (1)	KR101018491B1 (pl)
AT (1)	ATE461173T1 (pl)
AU (1)	AU2003290019B2 (pl)
BR (2)	BR0317176A (pl)
CA (1)	CA2509363C (pl)
CO (1)	CO5700810A2 (pl)
CY (1)	CY1110639T1 (pl)
DE (1)	DE60331770D1 (pl)
DK (1)	DK1572615T3 (pl)
EC (1)	ECSP055846A (pl)
ES (1)	ES2341336T3 (pl)
IL (1)	IL168866A (pl)
MX (1)	MXPA05006267A (pl)
NO (1)	NO331836B1 (pl)
NZ (1)	NZ540441A (pl)
PL (1)	PL206914B1 (pl)
PT (1)	PT1572615E (pl)
RU (1)	RU2392265C2 (pl)
SI (1)	SI1572615T1 (pl)
WO (1)	WO2004052817A1 (pl)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE4306839A1 (de) *	1993-03-05	1994-09-08	Bayer Ernst Prof Dr	Tritylgruppe enthaltendes Festphasensystem, Verfahren zu seiner Herstellung und seine Verwendung in Festphasenreaktionen
GB9502152D0 (en) *	1995-02-03	1995-03-29	Zeneca Ltd	Proline derivatives
MY147327A (en) *	1995-06-29	2012-11-30	Novartis Ag	Somatostatin peptides
GB9625167D0 (en) *	1996-12-04	1997-01-22	Sandoz Ltd	Organic compounds
WO1999001579A1 (en) *	1997-07-01	1999-01-14	Isis Pharmaceuticals, Inc.	Compositions and methods for the delivery of oligonucleotides via the alimentary canal
GB0018891D0 (en)	2000-08-01	2000-09-20	Novartis Ag	Organic compounds

2003
- 2003-12-11 US US10/538,028 patent/US7294722B2/en not_active Expired - Lifetime
- 2003-12-11 EP EP03782373A patent/EP1572615B8/en not_active Expired - Lifetime
- 2003-12-11 AU AU2003290019A patent/AU2003290019B2/en not_active Expired
- 2003-12-11 DK DK03782373.9T patent/DK1572615T3/da active
- 2003-12-11 KR KR1020057010600A patent/KR101018491B1/ko not_active Expired - Fee Related
- 2003-12-11 RU RU2005121664/04A patent/RU2392265C2/ru active
- 2003-12-11 ES ES03782373T patent/ES2341336T3/es not_active Expired - Lifetime
- 2003-12-11 PL PL375821A patent/PL206914B1/pl unknown
- 2003-12-11 PT PT03782373T patent/PT1572615E/pt unknown
- 2003-12-11 MX MXPA05006267A patent/MXPA05006267A/es active IP Right Grant
- 2003-12-11 WO PCT/EP2003/014082 patent/WO2004052817A1/en not_active Ceased
- 2003-12-11 JP JP2004558073A patent/JP4796303B2/ja not_active Expired - Lifetime
- 2003-12-11 CA CA2509363A patent/CA2509363C/en not_active Expired - Lifetime
- 2003-12-11 BR BR0317176-0A patent/BR0317176A/pt not_active IP Right Cessation
- 2003-12-11 NZ NZ540441A patent/NZ540441A/en not_active IP Right Cessation
- 2003-12-11 AT AT03782373T patent/ATE461173T1/de active
- 2003-12-11 DE DE60331770T patent/DE60331770D1/de not_active Expired - Lifetime
- 2003-12-11 BR BRPI0317176-0A patent/BRPI0317176B1/pt unknown
- 2003-12-11 SI SI200331800T patent/SI1572615T1/sl unknown
2005
- 2005-05-30 IL IL168866A patent/IL168866A/en active IP Right Grant
- 2005-06-09 EC EC2005005846A patent/ECSP055846A/es unknown
- 2005-06-14 CO CO05057286A patent/CO5700810A2/es active IP Right Grant
- 2005-07-11 NO NO20053374A patent/NO331836B1/no not_active IP Right Cessation
2007
- 2007-08-16 US US11/839,565 patent/US7449587B2/en not_active Expired - Lifetime
2008
- 2008-08-25 US US12/197,657 patent/US20080312456A1/en not_active Abandoned
2010
- 2010-04-05 JP JP2010086682A patent/JP5249276B2/ja not_active Expired - Lifetime
- 2010-05-14 CY CY20101100426T patent/CY1110639T1/el unknown

Also Published As

Publication number	Publication date
NO20053374L (no)	2005-09-12
US20080312456A1 (en)	2008-12-18
US20080021225A1 (en)	2008-01-24
CO5700810A2 (es)	2006-11-30
PL206914B1 (pl)	2010-10-29
ES2341336T3 (es)	2010-06-18
RU2005121664A (ru)	2006-02-27
NZ540441A (en)	2007-10-26
NO331836B1 (no)	2012-04-16
CA2509363C (en)	2012-04-24
EP1572615B8 (en)	2010-07-14
MXPA05006267A (es)	2005-08-19
NO20053374D0 (no)	2005-07-11
US20060189814A1 (en)	2006-08-24
IL168866A (en)	2010-12-30
ATE461173T1 (de)	2010-04-15
JP5249276B2 (ja)	2013-07-31
DK1572615T3 (da)	2010-06-14
US7449587B2 (en)	2008-11-11
KR101018491B1 (ko)	2011-03-03
SI1572615T1 (sl)	2010-06-30
BRPI0317176B1 (pt)	2018-03-13
JP2006509796A (ja)	2006-03-23
EP1572615B1 (en)	2010-03-17
RU2392265C2 (ru)	2010-06-20
PT1572615E (pt)	2010-04-14
AU2003290019A1 (en)	2004-06-30
US7294722B2 (en)	2007-11-13
AU2003290019B2 (en)	2007-09-27
JP2010209077A (ja)	2010-09-24
JP4796303B2 (ja)	2011-10-19
EP1572615A1 (en)	2005-09-14
WO2004052817A1 (en)	2004-06-24
KR20050085543A (ko)	2005-08-29
BR0317176A (pt)	2005-10-25
CY1110639T1 (el)	2015-04-29
DE60331770D1 (de)	2010-04-29
HK1085459A1 (en)	2006-08-25
CA2509363A1 (en)	2004-06-24
ECSP055846A (es)	2005-09-20

Publication	Publication Date	Title
IL154809A0 (en)	2003-10-31	Substituted dipeptides as growth hormone secretagogues
SE9903291D0 (sv)	1999-09-15	New process
SG144736A1 (en)	2008-08-28	Synthesis of temozolomide and analogs
AU2003255483A1 (en)	2004-04-19	Process for the conversion of polysulfanes
CA2290252A1 (en)	2000-05-23	Process and intermediates for growth hormone secretagogues
GB0317920D0 (en)	2003-09-03	Solid-phase synthesis
SG143062A1 (en)	2008-06-27	Synthesis of temozolomide and analogs
WO2004056769A3 (en)	2004-09-16	Synthesis of amines and intermediates for the synthesis thereof
TW200633977A (en)	2006-10-01	Novel process for the manufacture of 3-pyrrolidin-2-yl-propionic acid derivatives
IL184080A0 (en)	2007-10-31	Synthesis of peptide t-20 using peptide intermediate fragments
IL184081A0 (en)	2007-10-31	Synthesis using peptide intermediate fragments iii
IL168866A (en)	2010-12-30	Process for the synthesis of peptides containing a 4 - hydroxy-proline substructure
AU2003220441A1 (en)	2003-10-27	Dipeptidic growth hormone secretagogues
MXPA05008108A (es)	2005-09-21	Exo-(2r)(+))-2-amino-7-azabiciclo[2.2.1]heptan-7-carboxilato de terc-butilo, compuestos intermedios y procedimiento para prepararlos y aislarlos.
WO2003084942A3 (en)	2004-05-06	Stereoselective alkylation of chiral 2-methyl-4-protected piperazines
PL374961A1 (pl)	2005-11-14	Sposób wytwarzania produktów pośrednich
PL372933A1 (pl)	2005-08-08	Metylotiofenokarboksyanilidy
GB2441840A (en)	2008-03-19	Process for the synthesis of arylfluorenes and analogues thereof
PL373083A1 (pl)	2005-08-08	Sposób wytwarzania chlorowodorku benazeprilu
MXPA05003881A (es)	2005-10-05	Preparacion de compuestos triazospiro.
GB9924759D0 (en)	1999-12-22	Process for preparing peptide intermediates
AU2003273953A8 (en)	2004-04-23	Method for synthesizing peptides comprising at least one glycine molecule
TW200420553A (en)	2004-10-16	Process for the synthesis of 3, 3a, 6, 6a-tetrahydro-2H-cyclopentan[b]furan-2-one
TW200420552A (en)	2004-10-16	Dihydro-furan-2-one derivatives, their intermediates and methods of manufacture
AU2002314622A1 (en)	2002-12-23	Compound of formula (xr5-)(y+), process for synthesis