PL3759233T3 - Bioczujnik bioluminescencyjny do wykrywania i oznaczania ilościowego biocząsteczek - Google Patents

Bioczujnik bioluminescencyjny do wykrywania i oznaczania ilościowego biocząsteczek

Info

Publication number
PL3759233T3
PL3759233T3 PL19721157.6T PL19721157T PL3759233T3 PL 3759233 T3 PL3759233 T3 PL 3759233T3 PL 19721157 T PL19721157 T PL 19721157T PL 3759233 T3 PL3759233 T3 PL 3759233T3
Authority
PL
Poland
Prior art keywords
detecting
quantifying biomolecules
bioluminescent
biosensor
bioluminescent biosensor
Prior art date
Application number
PL19721157.6T
Other languages
English (en)
Other versions
PL3759233T4 (pl
Inventor
Maarten Merkx
Yan Ni
Eva Anna VAN AALEN
Original Assignee
Technische Universiteit Eindhoven
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technische Universiteit Eindhoven filed Critical Technische Universiteit Eindhoven
Publication of PL3759233T3 publication Critical patent/PL3759233T3/pl
Publication of PL3759233T4 publication Critical patent/PL3759233T4/pl

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/66Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving luciferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • G01N21/763Bioluminescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6845Methods of identifying protein-protein interactions in protein mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Plasma & Fusion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
PL19721157.6T 2018-02-26 2019-02-26 Bioczujnik bioluminescencyjny do wykrywania i oznaczania ilościowego biocząsteczek PL3759233T4 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862635053P 2018-02-26 2018-02-26
PCT/NL2019/050122 WO2019164402A1 (en) 2018-02-26 2019-02-26 Bioluminescent biosensor for detecting and quantifying biomolecules

Publications (2)

Publication Number Publication Date
PL3759233T3 true PL3759233T3 (pl) 2022-08-29
PL3759233T4 PL3759233T4 (pl) 2022-10-10

Family

ID=66349611

Family Applications (1)

Application Number Title Priority Date Filing Date
PL19721157.6T PL3759233T4 (pl) 2018-02-26 2019-02-26 Bioczujnik bioluminescencyjny do wykrywania i oznaczania ilościowego biocząsteczek

Country Status (8)

Country Link
US (2) US20210215682A1 (pl)
EP (1) EP3759233B1 (pl)
JP (1) JP7248693B2 (pl)
CN (1) CN112352055A (pl)
DK (1) DK3759233T3 (pl)
ES (1) ES2923526T3 (pl)
PL (1) PL3759233T4 (pl)
WO (1) WO2019164402A1 (pl)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115427556A (zh) * 2019-11-27 2022-12-02 普洛麦格公司 多部分萤光素酶肽和多肽
EP3916388A1 (en) * 2020-05-27 2021-12-01 Miltenyi Biotec B.V. & Co. KG Reagents for detection of chimeric antigen receptor cells
EP4192976A1 (en) * 2020-08-10 2023-06-14 The United States of America, as represented by the Secretary, Department of Health and Human Services Real-time cellular thermal shift assay (rt-cetsa) for research and drug discovery
CN116042766B (zh) * 2021-10-28 2025-02-11 同济大学 一种基于生物发光测定蛋白连接酶活力的组合物、方法及其应用
CN116256505B (zh) * 2021-12-09 2025-11-25 深圳先进技术研究院 基于qd-lumabs的抗体定量检测的曲线建立方法、检测方法及其试剂盒
CN114540419A (zh) * 2022-03-04 2022-05-27 中国人民解放军军事科学院军事医学研究院 一种分析包膜病毒膜融合效率的三功能报告系统
WO2023212662A2 (en) * 2022-04-28 2023-11-02 Oregon Health & Science University Compositions and methods for modulating antigen binding activity
EP4700040A1 (en) * 2023-04-21 2026-02-25 Shenzhen Loggene Life Science & Technology Co., Ltd. Peptide and luminescent complex containing same
CN120958035A (zh) * 2023-04-21 2025-11-14 深圳琅技生命科技有限公司 用于检测降钙素原的融合多肽、试剂盒及其应用
WO2025244967A1 (en) * 2024-05-20 2025-11-27 The Brigham And Women's Hospital, Inc. Compositions and methods for donor-specific antibody screening and tissue typing
WO2026019976A1 (en) * 2024-07-17 2026-01-22 The Broad Institute, Inc. Universal covalent crosslinker for antibody-oligo conjugates
CN119506317A (zh) * 2024-11-29 2025-02-25 河南中医药大学第一附属医院 用于fret探针构建的模块化质粒载体及其构建方法和应用

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE311596T1 (de) * 2001-04-23 2005-12-15 Eiken Chemical Analyseverfahren mit intermolekularer wechselwirkung eines reporters (markers)
JP2007529718A (ja) * 2004-03-12 2007-10-25 ザ スクリップス リサーチ インスティチュート 蛋白質活性の検出および定量のための蛍光シグナル発光型生細胞バイオセンサー分子ならびに色素
US7741128B2 (en) * 2005-05-23 2010-06-22 University Of Hawaii Cooperative reporter systems, components, and methods for analyte detection
CN101278194A (zh) * 2005-05-23 2008-10-01 夏威夷大学 用于分析物检测的协同指示系统、组分以及方法
CN101473031A (zh) * 2006-04-03 2009-07-01 普罗美加公司 变换和非变换的萤光素酶生物传感器
WO2014049142A1 (en) * 2012-09-27 2014-04-03 Technische Universiteit Eindhoven Switchable reporter enzymes for homogenous antibody detection
US9797890B2 (en) * 2013-03-15 2017-10-24 Promega Corporation Activation of bioluminescence by structural complementation
CN105555964B (zh) * 2013-07-18 2020-04-17 洛桑联邦理工学院 生物样品中进行生物发光共振能量转移(bret)分析的方式和方法
WO2015067302A1 (en) * 2013-11-05 2015-05-14 Ecole Polytechnique Federale De Lausanne (Epfl) Sensor molecules and uses thereof
EP2913338A1 (en) * 2014-02-28 2015-09-02 Roche Diagniostics GmbH Soluable and immunoreactive variants of HTLV capsid antigen p24
CN105807064B (zh) * 2014-12-31 2017-07-28 中国科学院深圳先进技术研究院 一种荧光素酶互补量子点生物传感器及其构建方法及其应用

Also Published As

Publication number Publication date
WO2019164402A1 (en) 2019-08-29
EP3759233B1 (en) 2022-03-30
US20210215682A1 (en) 2021-07-15
JP7248693B2 (ja) 2023-03-29
US20250180547A1 (en) 2025-06-05
JP2021515216A (ja) 2021-06-17
WO2019164402A8 (en) 2021-01-14
DK3759233T3 (da) 2022-07-11
PL3759233T4 (pl) 2022-10-10
EP3759233A1 (en) 2021-01-06
ES2923526T3 (es) 2022-09-28
CN112352055A (zh) 2021-02-09

Similar Documents

Publication Publication Date Title
PL3759233T4 (pl) Bioczujnik bioluminescencyjny do wykrywania i oznaczania ilościowego biocząsteczek
IL276637A (en) Methods and reagents for the detection and testing of genotoxicity
IL287261A (en) Compounds and methods for detecting analytes using bioluminescence
IL289907A (en) Methods and systems for identification and analysis of tested material
IL277726A (en) Methods for detection and quantification of FGF21
IL265396A (en) Methods and compositions for detecting analytes
GB201901277D0 (en) Defect centre-based sensor
PL3138489T3 (pl) Zestaw do określania stężenia analitu
ZA201907514B (en) Diagnostic assays for detecting, quantifying, and/or tracking microbes and other analytes
IL291166A (en) A method for identifying biomarkers
GB2582499B (en) PH control for analyte detection
IL254687B1 (en) A bio-sensor system for rapid identification of an analyte
SG11202112680XA (en) Rapid aneuploidy detection
GB201915139D0 (en) Sensor determination
IL277890B (en) Methods for quantifying il-33
EP4018176C0 (en) PARTICLE CONCENTRATION SENSOR SAMPLER DEVICE
KR102272812B9 (ko) 생체분자 분석용 나노 플라즈모닉 센서, 키트 및 이를 이용한 생체분자 분석 방법
HUE071293T2 (hu) Elektrokémiai szenzor legalább egy analit detektálásához
EP3593122A4 (en) METHOD OF DETECTION OF ANALYTES
IL267568A (en) A universal biosensor system for analytical detection
LT3752836T (lt) Sudėtinių dalių aptikimo būdai ir aparatas
SG10202002244UA (en) Sensor for detecting gas analyte
EP4004536A4 (en) APPARATUS AND METHODS FOR DETECTION AND QUANTIFICATION OF ANALYTES
GB201517279D0 (en) Method and system for improving the evaluation of an interaction between an analyte and a ligand using a biosensor
SI3565902T1 (sl) Postopek zaznavanja in kvantificiranja cirkulirajoče dnk in uporabe