PL377345A1 - Sposób wytwarzania sterylnych zawiesin wodnych do inhalacji, zawierających rozdrobnione do mikrocząstek krystaliczne składniki aktywne - Google Patents

Sposób wytwarzania sterylnych zawiesin wodnych do inhalacji, zawierających rozdrobnione do mikrocząstek krystaliczne składniki aktywne

Info

Publication number
PL377345A1
PL377345A1 PL377345A PL37734503A PL377345A1 PL 377345 A1 PL377345 A1 PL 377345A1 PL 377345 A PL377345 A PL 377345A PL 37734503 A PL37734503 A PL 37734503A PL 377345 A1 PL377345 A1 PL 377345A1
Authority
PL
Poland
Prior art keywords
active ingredients
sterile aqueous
suspensions containing
crystalline active
micronized crystalline
Prior art date
Application number
PL377345A
Other languages
English (en)
Other versions
PL213704B1 (pl
Inventor
Andrea Capocchi
Fausto Pivetti
Original Assignee
Chiesi Farmaceutici S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiesi Farmaceutici S.P.A. filed Critical Chiesi Farmaceutici S.P.A.
Publication of PL377345A1 publication Critical patent/PL377345A1/pl
Publication of PL213704B1 publication Critical patent/PL213704B1/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02—Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/022—Filtration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00—Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05—Living organisms or biological materials
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/68—Treatment of water, waste water, or sewage by addition of specified substances, e.g. trace elements, for ameliorating potable water
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2103/00—Nature of the water, waste water, sewage or sludge to be treated
    • C02F2103/02—Non-contaminated water, e.g. for industrial water supply
    • C02F2103/026—Treating water for medical or cosmetic purposes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
PL377345A 2002-12-18 2003-12-17 Sposób wytwarzania sterylnych preparatów w postaci wodnej zawiesiny PL213704B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT002674A ITMI20022674A1 (it) 2002-12-18 2002-12-18 Procedimento per la preparazione di formulazioni sterili a base di principi attivi farmaceutici cristallini micronizzati da somministrare come sospensioni acquose per inalazione.

Publications (2)

Publication Number Publication Date
PL377345A1 true PL377345A1 (pl) 2006-01-23
PL213704B1 PL213704B1 (pl) 2013-04-30

Family

ID=32587870

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377345A PL213704B1 (pl) 2002-12-18 2003-12-17 Sposób wytwarzania sterylnych preparatów w postaci wodnej zawiesiny

Country Status (22)

Country Link
US (1) US8128909B2 (pl)
EP (1) EP1572153B1 (pl)
CN (1) CN100398095C (pl)
AT (1) ATE544445T1 (pl)
AU (1) AU2003294879A1 (pl)
BR (1) BRPI0316908B8 (pl)
CA (1) CA2510263C (pl)
DK (1) DK1572153T3 (pl)
EA (1) EA008122B1 (pl)
ES (1) ES2379349T3 (pl)
HR (1) HRP20050546B1 (pl)
IT (1) ITMI20022674A1 (pl)
MA (1) MA27702A1 (pl)
ME (2) MEP35208A (pl)
MX (1) MXPA05006441A (pl)
PL (1) PL213704B1 (pl)
PT (1) PT1572153E (pl)
RS (1) RS52151B (pl)
SI (1) SI1572153T1 (pl)
UA (1) UA87655C2 (pl)
WO (1) WO2004054545A1 (pl)
ZA (1) ZA200504897B (pl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9704186D0 (sv) 1997-11-14 1997-11-14 Astra Ab New composition of matter
ITMI20020808A1 (it) * 2002-04-17 2003-10-17 Chiesi Farma Spa Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione
US9808471B2 (en) * 2003-04-16 2017-11-07 Mylan Specialty Lp Nasal pharmaceutical formulations and methods of using the same
US8912174B2 (en) 2003-04-16 2014-12-16 Mylan Pharmaceuticals Inc. Formulations and methods for treating rhinosinusitis
US7811606B2 (en) * 2003-04-16 2010-10-12 Dey, L.P. Nasal pharmaceutical formulations and methods of using the same
ITMI20032054A1 (it) * 2003-10-22 2005-04-23 Monteres S R L Processo per la preparazione di sospensioni farmaceutiche da inalare.
PE20050941A1 (es) * 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
DE602005009012D1 (de) * 2004-10-12 2008-09-25 Generics Uk Ltd Rmulierungen, worin die partikel durch präzipition in einem aerosolbehälter gebildet werden
EP1949891A1 (en) * 2004-10-12 2008-07-30 Generics (UK) Limited Process for the preparation of suspension aerosol formulations, wherein the particles are formed by precipitation inside an aerosol canister
EP1683514B1 (en) 2005-01-20 2012-05-23 Eratech S.r.l. Process for the preparation of concentrated suspensions of drugs and kit thereof
EP1782797A1 (en) * 2005-11-02 2007-05-09 Pharmatex Italia Srl Process for the preparation of sterile powdered pharmaceutical compounds.
US20080262078A1 (en) * 2007-04-20 2008-10-23 Namdeo Alok B Pharmaceutical Compositions
SI2170279T1 (en) * 2007-07-31 2018-04-30 Otsuka Pharmaceutical Co., Ltd. Methods for producing aripiprazole suspension and freeze-dried formulation
BRPI0820745A2 (pt) * 2007-12-13 2015-06-16 Novartis Ag Compostos orgânicos
GB0806873D0 (en) * 2008-04-16 2008-05-21 Breath Ltd Steroid nebuliser formulation
CN101618019B (zh) * 2008-07-01 2011-08-03 上海通用药业股份有限公司 一种醋酸曲安奈德微粒及其制备方法和药物组合物
EP2663287A1 (en) 2011-01-12 2013-11-20 Intervet International B.V. Use of liquid medium exchange by cross flow filtration in the preparation of drug suspensions
ES2612257T3 (es) 2011-05-03 2017-05-16 Chiesi Farmaceutici S.P.A. Formulación de suspensión mejorada de dipropionato de beclometasona para administración mediante inhalación
JP4954345B1 (ja) * 2011-07-06 2012-06-13 アピ株式会社 医薬品原薬の無菌化精製装置
EP2847207B1 (en) * 2012-05-08 2019-03-27 Nicox Ophthalmics, Inc. Fluticasone propionate nanocrystals
DE102012221219B4 (de) * 2012-11-20 2014-05-28 Jesalis Pharma Gmbh Verfahren zur Vergrößerung der Partikelgröße kristalliner Wirkstoff-Mikropartikel
DK3689332T3 (da) 2014-09-09 2026-03-23 Vectura Ltd Formulering, som omfatter glycopyrrolat, fremgangsmåde og apparat
EP3153606B1 (fr) * 2015-10-09 2019-10-09 Bgh Procede pour cristalliser des clathrates hydrates, et procede de purification d'un liquide aqueux utilisant les clathrates hydrates ainsi cristallises
WO2024180569A1 (en) * 2023-03-01 2024-09-06 Ajaykumar Balraj Kanduri A synergistic aqueous nebulization suspension for management of infectious respiratory disorders and process of preparation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2107715B (en) * 1981-10-19 1985-11-13 Glaxo Group Ltd Micronised beclomethasone dipropionate monohydrate and powder inhalation compositions containing it
US6187765B1 (en) * 1997-10-09 2001-02-13 Schering Corporation Mometasone furoate suspensions for nebulization
ATE228823T1 (de) * 1998-04-18 2002-12-15 Glaxo Group Ltd Pharmazeutische aerosolformulierung
US6241969B1 (en) * 1998-06-26 2001-06-05 Elan Corporation Plc Aqueous compositions containing corticosteroids for nasal and pulmonary delivery
IT1303692B1 (it) * 1998-11-03 2001-02-23 Chiesi Farma Spa Procedimento per la preparazione di sospensioni di particelle difarmaci da somministrare per inalazione.
GB0015981D0 (en) * 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
GB0016040D0 (en) 2000-06-29 2000-08-23 Glaxo Group Ltd Novel process for preparing crystalline particles
WO2003070285A1 (en) 2002-02-19 2003-08-28 Resolution Chemicals Limited Solvent-based sterilisation of pharmaceuticals

Also Published As

Publication number Publication date
AU2003294879A1 (en) 2004-07-09
MEP35208A (bs) 2011-02-10
CA2510263A1 (en) 2004-07-01
US20070140980A1 (en) 2007-06-21
MXPA05006441A (es) 2005-09-08
RS72504A (sr) 2006-10-27
BRPI0316908B1 (pt) 2016-01-26
US8128909B2 (en) 2012-03-06
SI1572153T1 (sl) 2012-05-31
ITMI20022674A1 (it) 2004-06-19
BRPI0316908B8 (pt) 2021-05-25
EP1572153B1 (en) 2012-02-08
MA27702A1 (fr) 2006-01-02
CN100398095C (zh) 2008-07-02
EP1572153A1 (en) 2005-09-14
ME01084B (me) 2011-05-10
EA200500833A1 (ru) 2006-02-24
DK1572153T3 (da) 2012-03-05
PL213704B1 (pl) 2013-04-30
ES2379349T3 (es) 2012-04-25
HRP20050546B1 (hr) 2014-05-23
ATE544445T1 (de) 2012-02-15
CN1735403A (zh) 2006-02-15
HRP20050546A2 (en) 2005-10-31
ZA200504897B (en) 2006-09-27
PT1572153E (pt) 2012-03-22
HK1088217A1 (zh) 2006-11-03
EA008122B1 (ru) 2007-04-27
CA2510263C (en) 2012-07-03
WO2004054545A1 (en) 2004-07-01
RS52151B (sr) 2012-08-31
BR0316908A (pt) 2005-10-18
UA87655C2 (ru) 2009-08-10

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