PL377504A1 - Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives as pharmaceutical agents - Google Patents
Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives as pharmaceutical agentsInfo
- Publication number
- PL377504A1 PL377504A1 PL377504A PL37750403A PL377504A1 PL 377504 A1 PL377504 A1 PL 377504A1 PL 377504 A PL377504 A PL 377504A PL 37750403 A PL37750403 A PL 37750403A PL 377504 A1 PL377504 A1 PL 377504A1
- Authority
- PL
- Poland
- Prior art keywords
- arylene
- phenyl
- amino
- carboxylic acid
- pharmaceutical agents
- Prior art date
Links
- 239000008177 pharmaceutical agent Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D333/40—Thiophene-2-carboxylic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/77—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/42—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having nitrogen atoms of amino groups bound to the carbon skeleton of the acid part, further acylated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/04—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms
- C07C275/20—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton
- C07C275/24—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/10—Systems containing only non-condensed rings with a five-membered ring the ring being unsaturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02027579 | 2002-12-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL377504A1 true PL377504A1 (en) | 2006-02-06 |
Family
ID=32479720
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL377504A PL377504A1 (en) | 2002-12-10 | 2003-12-09 | Arylene-carboxylic acid (2-amino-phenyl)-amide derivatives as pharmaceutical agents |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7098247B2 (en) |
| EP (1) | EP1572625A1 (en) |
| JP (1) | JP2006509021A (en) |
| KR (1) | KR100759744B1 (en) |
| CN (2) | CN101279927A (en) |
| AR (1) | AR042341A1 (en) |
| AU (1) | AU2003289992A1 (en) |
| BR (1) | BR0317027A (en) |
| CA (1) | CA2507137A1 (en) |
| GT (1) | GT200300274A (en) |
| MX (1) | MXPA05005977A (en) |
| PA (1) | PA8590901A1 (en) |
| PE (1) | PE20040768A1 (en) |
| PL (1) | PL377504A1 (en) |
| RU (1) | RU2345061C2 (en) |
| TW (1) | TW200426138A (en) |
| UY (1) | UY28108A1 (en) |
| WO (1) | WO2004052838A1 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7154002B1 (en) | 2002-10-08 | 2006-12-26 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| US7250514B1 (en) | 2002-10-21 | 2007-07-31 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| CA2518318A1 (en) | 2003-03-17 | 2004-09-30 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| DK1696898T3 (en) * | 2003-12-02 | 2016-02-22 | Univ Ohio State Res Found | ZN2 + -CHELATING DESIGN-BASED SHORT-CHAIN FAT ACIDS AS AN UNKNOWN CLASS OF HISTONDEACETYLASE INHIBITORS |
| JP2008524246A (en) * | 2004-12-16 | 2008-07-10 | タケダ サン ディエゴ インコーポレイテッド | Histone deacetylase inhibitor |
| US7642253B2 (en) | 2005-05-11 | 2010-01-05 | Takeda San Diego, Inc. | Histone deacetylase inhibitors |
| EA200800321A1 (en) | 2005-07-14 | 2008-06-30 | Такеда Сан Диего, Инк. | HISTONDEACETYLASE INHIBITORS |
| JP2009528354A (en) * | 2006-02-28 | 2009-08-06 | メルク エンド カムパニー インコーポレーテッド | Inhibitors of histone deacetylase |
| EP2135620A4 (en) * | 2007-03-28 | 2010-12-29 | Santen Pharmaceutical Co Ltd | Ocular hypotensive agent comprising compound capable of inhibiting histone deacetylase as active ingredient |
| WO2008117862A1 (en) | 2007-03-28 | 2008-10-02 | Santen Pharmaceutical Co., Ltd. | Novel (2-aminophenyl)pyridinecarboxamide derivative having urea structure |
| JP2011501746A (en) * | 2007-10-10 | 2011-01-13 | オーキッド リサーチ ラボラトリーズ リミテッド | Novel histone deacetylase inhibitor |
| US8198271B2 (en) | 2008-05-23 | 2012-06-12 | Santen Pharmaceutical Co., Ltd. | Thiophenediamine derivative having urea structure |
| EP2330894B8 (en) | 2008-09-03 | 2017-04-19 | BioMarin Pharmaceutical Inc. | Compositions including 6-aminohexanoic acid derivatives as hdac inhibitors |
| WO2010144378A2 (en) * | 2009-06-08 | 2010-12-16 | Gilead Colorado, Inc. | Cycloalkylcarbamate benzamide aniline hdac inhibitor compounds |
| US10059723B2 (en) | 2011-02-28 | 2018-08-28 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| US8957066B2 (en) | 2011-02-28 | 2015-02-17 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| US9540395B2 (en) | 2011-02-28 | 2017-01-10 | Biomarin Pharmaceutical Inc. | Histone deacetylase inhibitors |
| WO2014143666A1 (en) | 2013-03-15 | 2014-09-18 | Biomarin Pharmaceutical Inc. | Hdac inhibitors |
| PL237497B1 (en) * | 2018-09-17 | 2021-04-19 | Univ Medyczny Im Piastow Slaskich We Wroclawiu | N'-[(anthracen-9-yl)methylene]-2 [4,6-dimethyl-2-sulfanyl-pyridin-3-yl-carboxamido]acetic acid hydrazide, its preparation and use |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1033046B (en) | 1970-10-31 | 1979-07-10 | Finotto Martino | PROCESS FOR MANUFACTURING SUBSTITUTED BENZIMIDAZOLES |
| DE2201062A1 (en) | 1972-01-11 | 1973-07-26 | Bayer Ag | N-ALKOXYCARBONYL- OR N-ALKYLTHIOCARBONYL-2- (2'-THIENYL) -ENZIMIDAZOLE, A METHOD FOR THEIR PRODUCTION AND USE AS FUNGICIDES |
| NZ219974A (en) * | 1986-04-22 | 1989-08-29 | Goedecke Ag | N-(2'-aminophenyl)-benzamide derivatives, process for their preparation and their use in the control of neoplastic diseases |
| JPH0242851A (en) * | 1988-08-02 | 1990-02-13 | Nec Corp | Line selecting device |
| ES2176252T3 (en) * | 1993-07-02 | 2002-12-01 | Altana Pharma Ag | BENZAMIDS REPLACED WITH FLUORO-ALCOXI AND ITS USE AS INHIBITING AGENTS OF PHOSPHODIESTERASES OF CYCLIC NUCLEOTIDES. |
| JPH0847992A (en) * | 1994-08-05 | 1996-02-20 | Nippon Petrochem Co Ltd | Three-dimensional composite reinforcement by high elastic mesh web and its manufacturing method |
| US6174905B1 (en) * | 1996-09-30 | 2001-01-16 | Mitsui Chemicals, Inc. | Cell differentiation inducer |
-
2003
- 2003-12-04 TW TW092134188A patent/TW200426138A/en unknown
- 2003-12-05 PA PA20038590901A patent/PA8590901A1/en unknown
- 2003-12-08 UY UY28108A patent/UY28108A1/en not_active Application Discontinuation
- 2003-12-08 GT GT200300274A patent/GT200300274A/en unknown
- 2003-12-09 PL PL377504A patent/PL377504A1/en not_active Application Discontinuation
- 2003-12-09 EP EP03782343A patent/EP1572625A1/en not_active Withdrawn
- 2003-12-09 CN CNA2008100962769A patent/CN101279927A/en active Pending
- 2003-12-09 JP JP2004558040A patent/JP2006509021A/en active Pending
- 2003-12-09 CA CA002507137A patent/CA2507137A1/en not_active Abandoned
- 2003-12-09 KR KR1020057010551A patent/KR100759744B1/en not_active Expired - Fee Related
- 2003-12-09 CN CNA2003801054973A patent/CN1723192A/en active Pending
- 2003-12-09 AU AU2003289992A patent/AU2003289992A1/en not_active Abandoned
- 2003-12-09 BR BR0317027-6A patent/BR0317027A/en not_active IP Right Cessation
- 2003-12-09 WO PCT/EP2003/013941 patent/WO2004052838A1/en not_active Ceased
- 2003-12-09 RU RU2005121662/04A patent/RU2345061C2/en not_active IP Right Cessation
- 2003-12-09 MX MXPA05005977A patent/MXPA05005977A/en active IP Right Grant
- 2003-12-09 AR ARP030104526A patent/AR042341A1/en unknown
- 2003-12-09 PE PE2003001241A patent/PE20040768A1/en not_active Application Discontinuation
- 2003-12-10 US US10/732,026 patent/US7098247B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7098247B2 (en) | 2006-08-29 |
| CN101279927A (en) | 2008-10-08 |
| KR100759744B1 (en) | 2007-10-04 |
| MXPA05005977A (en) | 2005-08-18 |
| RU2345061C2 (en) | 2009-01-27 |
| PA8590901A1 (en) | 2004-11-26 |
| CA2507137A1 (en) | 2004-06-24 |
| CN1723192A (en) | 2006-01-18 |
| KR20050088421A (en) | 2005-09-06 |
| RU2005121662A (en) | 2006-01-27 |
| UY28108A1 (en) | 2004-06-30 |
| US20040138270A1 (en) | 2004-07-15 |
| AR042341A1 (en) | 2005-06-15 |
| BR0317027A (en) | 2005-10-25 |
| WO2004052838A1 (en) | 2004-06-24 |
| TW200426138A (en) | 2004-12-01 |
| PE20040768A1 (en) | 2004-11-20 |
| JP2006509021A (en) | 2006-03-16 |
| AU2003289992A1 (en) | 2004-06-30 |
| EP1572625A1 (en) | 2005-09-14 |
| GT200300274A (en) | 2004-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REFS | Decisions on refusal to grant patents (taken after the publication of the particulars of the applications) |